ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of the force of heart contraction
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Accession:GO:0002026 term browser browse the term
Definition:Any process that modulates the extent of heart contraction, changing the force with which blood is propelled.
Synonyms:exact_synonym: cardiac inotropy;   heart inotropy


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regulation of the force of heart contraction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adm adrenomedullin JBrowse link 1 175,443,189 175,447,260 RGD:2325635
G Apln apelin JBrowse link X 134,856,719 134,866,210 RGD:1626171
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 JBrowse link 2 204,003,742 204,032,023 RGD:1624291
RGD:1600115
G Atp1a2 ATPase Na+/K+ transporting subunit alpha 2 JBrowse link 13 90,651,682 90,676,629 RGD:1624291
RGD:1600115
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 JBrowse link 12 39,553,903 39,603,326 RGD:1624291
RGD:1600115
G Cav1 caveolin 1 JBrowse link 4 44,597,123 44,630,206 RGD:1624291
G Chga chromogranin A JBrowse link 6 126,434,226 126,445,569 RGD:6906968
G Csrp3 cysteine and glycine rich protein 3 JBrowse link 1 104,147,205 104,166,389 RGD:1624291
RGD:1600115
G Gaa glucosidase, alpha, acid JBrowse link 10 108,395,873 108,412,999 RGD:1624291
RGD:1600115
G Glrx3 glutaredoxin 3 JBrowse link 1 209,768,696 209,799,912 RGD:1624291
RGD:1600115
G Grk2 G protein-coupled receptor kinase 2 JBrowse link 1 219,536,220 219,544,329 RGD:1624291
G Ifng interferon gamma JBrowse link 7 61,337,383 61,341,419 RGD:2311499
G Myh6 myosin heavy chain 6 JBrowse link 15 33,605,653 33,629,730 RGD:1624291
RGD:1600115
G Myh7 myosin heavy chain 7 JBrowse link 15 33,605,769 33,657,761 RGD:1624291
RGD:1600115
G Myl2 myosin light chain 2 JBrowse link 12 39,951,863 39,959,065 RGD:10400860
G Myl3 myosin light chain 3 JBrowse link 8 119,030,852 119,036,996 RGD:1624291
RGD:1600115
G Myl4 myosin, light chain 4 JBrowse link 10 92,628,356 92,638,100 RGD:1624291
RGD:1600115
G Pbp2 phosphatidylethanolamine binding protein 2 JBrowse link 4 169,091,841 169,093,135 RGD:13792537
G Pde5a phosphodiesterase 5A JBrowse link 2 226,899,604 227,044,916 RGD:2314467
G Pebp1 phosphatidylethanolamine binding protein 1 JBrowse link 12 45,026,948 45,031,148 RGD:2302820
RGD:13792537
G Pln phospholamban JBrowse link 20 34,633,157 34,642,904 RGD:1624291
G Prkca protein kinase C, alpha JBrowse link 10 96,186,509 96,585,168 RGD:1624291
G Slc8a1 solute carrier family 8 member A1 JBrowse link 6 4,244,076 4,564,262 RGD:1624291
G Slc9a1 solute carrier family 9 member A1 JBrowse link 5 151,573,122 151,626,360 RGD:6771329
negative regulation of the force of heart contraction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atp2b4 ATPase plasma membrane Ca2+ transporting 4 JBrowse link 13 50,091,644 50,153,808 RGD:1624291
RGD:1600115
negative regulation of the force of heart contraction by chemical signal term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Grk2 G protein-coupled receptor kinase 2 JBrowse link 1 219,536,220 219,544,329 RGD:1624291
RGD:1600115
positive regulation of the force of heart contraction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Myl2 myosin light chain 2 JBrowse link 12 39,951,863 39,959,065 RGD:1600115
RGD:1624291
G Nos1 nitric oxide synthase 1 JBrowse link 12 44,214,949 44,405,530 RGD:1624291
RGD:1600115
G Ryr2 ryanodine receptor 2 JBrowse link 17 65,533,998 65,955,606 RGD:1624291
RGD:1600115
G Slc8a1 solute carrier family 8 member A1 JBrowse link 6 4,244,076 4,564,262 RGD:1624291
RGD:1600115
G Slc9a1 solute carrier family 9 member A1 JBrowse link 5 151,573,122 151,626,360 RGD:1624291
RGD:1600115
positive regulation of the force of heart contraction by epinephrine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adrb2 adrenoceptor beta 2 JBrowse link 18 57,513,792 57,515,834 RGD:5129126
positive regulation of the force of heart contraction by epinephrine-norepinephrine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adra1a adrenoceptor alpha 1A JBrowse link 15 43,296,997 43,398,314 RGD:1624291
RGD:1600115
G Adra1b adrenoceptor alpha 1B JBrowse link 10 29,392,762 29,450,644 RGD:1624291
G Adrb1 adrenoceptor beta 1 JBrowse link 1 277,537,585 277,538,985 RGD:1600115
RGD:1624291
positive regulation of the force of heart contraction by norepinephrine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adrb1 adrenoceptor beta 1 JBrowse link 1 277,537,585 277,538,985 RGD:5129126
regulation of the force of heart contraction by cardiac conduction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pln phospholamban JBrowse link 20 34,633,157 34,642,904 RGD:1624291
RGD:1600115
G Slc9a1 solute carrier family 9 member A1 JBrowse link 5 151,573,122 151,626,360 RGD:1624291
RGD:1600115
regulation of the force of heart contraction by chemical signal term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cav1 caveolin 1 JBrowse link 4 44,597,123 44,630,206 RGD:1624291
RGD:1600115
G Nos3 nitric oxide synthase 3 JBrowse link 4 7,321,908 7,342,404 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17896
    biological regulation 12607
      regulation of biological quality 4125
        regulation of the force of heart contraction 32
          negative regulation of the force of heart contraction 1
          positive regulation of the force of heart contraction 5
          regulation of the force of heart contraction by cardiac conduction 2
          regulation of the force of heart contraction by chemical signal + 7
Path 2
Term Annotations click to browse term
  biological_process 17896
    multicellular organismal process 8524
      system process 3249
        circulatory system process 518
          blood circulation 509
            heart contraction 231
              regulation of heart contraction 189
                regulation of the force of heart contraction 32
                  negative regulation of the force of heart contraction 1
                  positive regulation of the force of heart contraction 5
                  regulation of the force of heart contraction by cardiac conduction 2
                  regulation of the force of heart contraction by chemical signal + 7
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.