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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of heart rate
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Accession:GO:0002027 term browser browse the term
Definition:Any process that modulates the frequency or rate of heart contraction.
Synonyms:exact_synonym: cardiac chronotropy;   regulation of heart contraction rate;   regulation of rate of heart contraction


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regulation of heart rate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGT angiotensinogen IEA Ensembl GO_REF:0000107 NCBI chr 1:230,702,523...230,745,583
Ensembl chr 1:230,702,523...230,714,122
JBrowse link
G ANK2 ankyrin 2 IMP (PMID:18832177) BHF-UCL PMID:18832177 NCBI chr 4:112,705,622...113,383,736
Ensembl chr 4:112,818,032...113,384,221
JBrowse link
G BVES blood vessel epicardial substance IEA Ensembl GO_REF:0000107 NCBI chr 6:105,096,822...105,137,157
Ensembl chr 6:105,096,822...105,137,157
JBrowse link
G CACNA1E calcium voltage-gated channel subunit alpha1 E ISO (MGI:MGI:3614618|PMID:14976402) MGI PMID:14976402 MGI:MGI:3614618 NCBI chr 1:181,317,712...181,808,084
Ensembl chr 1:181,317,690...181,808,084
JBrowse link
G CACNA1G calcium voltage-gated channel subunit alpha1 G ISO (MGI:MGI:3714901|PMID:16690884) MGI PMID:16690884 MGI:MGI:3714901 NCBI chr17:50,560,715...50,629,625
Ensembl chr17:50,560,715...50,627,474
JBrowse link
G CALCA calcitonin related polypeptide alpha ISO (MGI:MGI:2445452|PMID:11717154) MGI PMID:11717154 MGI:MGI:2445452 NCBI chr11:14,966,668...14,972,361
Ensembl chr11:14,966,668...14,972,354
JBrowse link
G CALM1 calmodulin 1 IMP (PMID:23040497) BHF-UCL PMID:23040497 NCBI chr14:90,396,502...90,408,268
Ensembl chr14:90,396,502...90,408,268
JBrowse link
G CALM2 calmodulin 2 IMP (PMID:23040497) BHF-UCL PMID:23040497 NCBI chr 2:47,160,082...47,176,936
Ensembl chr 2:47,160,083...47,176,921
JBrowse link
G CALM3 calmodulin 3 IMP (PMID:23040497) BHF-UCL PMID:23040497 NCBI chr19:46,601,074...46,610,782
Ensembl chr19:46,601,074...46,610,782
JBrowse link
G CASQ2 calsequestrin 2 IMP (PMID:15485681), (PMID:16601229), (PMID:16908766) UniProtKB PMID:15485681, PMID:16601229, PMID:16908766 NCBI chr 1:115,700,021...115,768,714
Ensembl chr 1:115,700,021...115,768,714
Ensembl chr 1:115,700,021...115,768,714
JBrowse link
G CAV3 caveolin 3 IMP (PMID:17060380) BHF-UCL PMID:17060380 NCBI chr 3:8,733,802...8,746,758
Ensembl chr 3:8,733,802...8,841,808
Ensembl chr 3:8,733,802...8,841,808
JBrowse link
G DMD dystrophin IMP
IEA
(PMID:19027585) BHF-UCL
Ensembl
PMID:19027585 GO_REF:0000107 NCBI chr  X:31,119,219...33,339,460
Ensembl chr  X:31,097,677...33,339,441
JBrowse link
G DRD2 dopamine receptor D2 ISS BHF-UCL GO_REF:0000024 NCBI chr11:113,409,605...113,475,398
Ensembl chr11:113,409,605...113,475,691
JBrowse link
G EPAS1 endothelial PAS domain protein 1 IEA Ensembl GO_REF:0000107 NCBI chr 2:46,297,407...46,386,697
Ensembl chr 2:46,293,667...46,386,697
JBrowse link
G FKBP1B FKBP prolyl isomerase 1B ISO (MGI:MGI:3639647|PMID:16672364) MGI PMID:16672364 MGI:MGI:3639647 NCBI chr 2:24,033,205...24,067,743
Ensembl chr 2:24,049,701...24,063,681
JBrowse link
G FPGT-TNNI3K FPGT-TNNI3K readthrough IMP
IGI
(PMID:24925317)
(PMID:23236294)
BHF-UCL PMID:23236294, PMID:24925317 NCBI chr 1:74,198,242...74,544,428
Ensembl chr 1:74,198,235...74,544,393
JBrowse link
G GPD1L glycerol-3-phosphate dehydrogenase 1 like IMP (PMID:17967977), (PMID:19666841) BHF-UCL PMID:17967977, PMID:19666841 NCBI chr 3:32,106,620...32,168,715
Ensembl chr 3:32,105,689...32,168,713
Ensembl chr 3:32,105,689...32,168,713
JBrowse link
G HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4 IMP (PMID:16407510) UniProtKB PMID:16407510 NCBI chr15:73,319,859...73,368,958
Ensembl chr15:73,319,859...73,368,958
JBrowse link
G HRC histidine rich calcium binding protein IMP (PMID:18617481) BHF-UCL PMID:18617481 NCBI chr19:49,151,198...49,155,464
Ensembl chr19:49,151,198...49,155,396
JBrowse link
G IRX5 iroquois homeobox 5 IEA Ensembl GO_REF:0000107 NCBI chr16:54,930,865...54,934,485
Ensembl chr16:54,930,865...54,934,485
JBrowse link
G MC3R melanocortin 3 receptor IEA Ensembl GO_REF:0000107 NCBI chr20:56,248,732...56,249,815
Ensembl chr20:56,248,732...56,249,815
JBrowse link
G MDM2 MDM2 proto-oncogene IEA Ensembl GO_REF:0000107 NCBI chr12:68,808,149...68,850,686
Ensembl chr12:68,808,177...68,850,686
JBrowse link
G MDM4 MDM4 regulator of p53 ISO (MGI:MGI:5440773|PMID:22821713) MGI PMID:22821713 MGI:MGI:5440773 NCBI chr 1:204,516,377...204,558,120
Ensembl chr 1:204,516,379...204,558,120
JBrowse link
G MYBPC3 myosin binding protein C3 ISO (MGI:MGI:1352072|PMID:10532952) MGI PMID:10532952 MGI:MGI:1352072 NCBI chr11:47,331,406...47,352,702
Ensembl chr11:47,331,406...47,352,702
JBrowse link
G MYH6 myosin heavy chain 6 IDA (PMID:15621050) HGNC PMID:15621050 NCBI chr14:23,381,987...23,408,273
Ensembl chr14:23,381,982...23,408,273
JBrowse link
G MYH7 myosin heavy chain 7 IDA (PMID:15621050) HGNC PMID:15621050 NCBI chr14:23,412,740...23,435,677
Ensembl chr14:23,412,740...23,435,660
JBrowse link
G OXT oxytocin/neurophysin I prepropeptide IEA Ensembl GO_REF:0000107 NCBI chr20:3,068,871...3,072,517
Ensembl chr20:3,071,620...3,072,517
JBrowse link
G PDE4D phosphodiesterase 4D ISS (PMID:16213210) BHF-UCL PMID:16213210 NCBI chr 5:58,969,038...60,524,329
Ensembl chr 5:58,969,038...60,522,120
JBrowse link
G PMCH pro-melanin concentrating hormone ISO RGD PMID:17045349 RGD:1642492 NCBI chr12:102,196,459...102,199,540
Ensembl chr12:102,196,459...102,197,833
JBrowse link
G POPDC2 popeye domain containing 2 ISS UniProtKB GO_REF:0000024 NCBI chr 3:119,642,056...119,660,589
Ensembl chr 3:119,636,457...119,665,324
JBrowse link
G PRKACA protein kinase cAMP-activated catalytic subunit alpha TAS (PMID:23507255) BHF-UCL PMID:23507255 NCBI chr19:14,091,688...14,117,762
Ensembl chr19:14,091,688...14,118,084
JBrowse link
G RANGRF RAN guanine nucleotide release factor TAS (PMID:21621375) BHF-UCL PMID:21621375 NCBI chr17:8,288,670...8,290,087
Ensembl chr17:8,288,654...8,290,092
JBrowse link
G RYR2 ryanodine receptor 2 IMP (PMID:11159936), (PMID:12919952), (PMID:15197150) BHF-UCL PMID:11159936, PMID:12919952, PMID:15197150 NCBI chr 1:237,042,184...237,833,988
Ensembl chr 1:237,042,184...237,833,988
JBrowse link
G SCN10A sodium voltage-gated channel alpha subunit 10 IMP (PMID:20062061), (PMID:21041692) BHF-UCL PMID:20062061, PMID:21041692 NCBI chr 3:38,696,807...38,816,217
Ensembl chr 3:38,696,802...38,816,286
JBrowse link
G SCN5A sodium voltage-gated channel alpha subunit 5 IMP
IBA
(PMID:10471492), (PMID:18065446), (PMID:18616619), (PMID:21895525), (PMID:22529811), (PMID:23085483), (PMID:26279430), (PMID:26392562)
(PMID:21873635)
BHF-UCL
GO_Central
PMID:10471492, PMID:18065446, PMID:18616619, PMID:21873635, PMID:21895525, PMID:22529811, PMID:23085483, PMID:26279430, PMID:26392562 NCBI chr 3:38,548,061...38,649,687
Ensembl chr 3:38,548,057...38,649,687
Ensembl chr 3:38,548,057...38,649,687
JBrowse link
G SEMA3A semaphorin 3A IEA Ensembl GO_REF:0000107 NCBI chr 7:83,955,777...84,515,189
Ensembl chr 7:83,955,777...84,492,724
JBrowse link
G SLC8A1 solute carrier family 8 member A1 ISS BHF-UCL GO_REF:0000024 NCBI chr 2:40,094,523...40,512,452
Ensembl chr 2:40,097,270...40,611,053
JBrowse link
G SNTA1 syntrophin alpha 1 IMP (PMID:18591664) BHF-UCL PMID:18591664 NCBI chr20:33,407,957...33,443,853
Ensembl chr20:33,407,957...33,443,763
Ensembl chr20:33,407,957...33,443,763
JBrowse link
G TNNI3K TNNI3 interacting kinase IMP
IGI
(PMID:24925317)
(PMID:23236294)
BHF-UCL PMID:23236294, PMID:24925317 NCBI chr 1:74,235,387...74,544,428
Ensembl chr 1:74,235,387...74,544,428
JBrowse link
G TRPV4 transient receptor potential cation channel subfamily V member 4 NOT ISO PMID:23136043 UniProt PMID:23136043 RGD:10400856 NCBI chr12:109,783,087...109,833,398
Ensembl chr12:109,783,087...109,833,406
Ensembl chr12:109,783,087...109,833,406
JBrowse link
adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PDE4D phosphodiesterase 4D IC BHF-UCL GO_REF:0000036 NCBI chr 5:58,969,038...60,524,329
Ensembl chr 5:58,969,038...60,522,120
JBrowse link
negative regulation of heart rate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGTR2 angiotensin II receptor type 2 ISS BHF-UCL GO_REF:0000024 NCBI chr  X:116,170,744...116,174,974
Ensembl chr  X:116,170,744...116,174,974
JBrowse link
G FKBP1B FKBP prolyl isomerase 1B ISS BHF-UCL GO_REF:0000024 NCBI chr 2:24,033,205...24,067,743
Ensembl chr 2:24,049,701...24,063,681
JBrowse link
G NPFF neuropeptide FF-amide peptide precursor IEA Ensembl GO_REF:0000107 NCBI chr12:53,506,688...53,507,484
Ensembl chr12:53,506,690...53,507,638
JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 ISO RGD PMID:19015400 RGD:4108483 NCBI chr 5:68,215,737...68,301,821
Ensembl chr 5:68,215,756...68,301,821
JBrowse link
G PLN phospholamban IMP (PMID:16432188) BHF-UCL PMID:16432188 NCBI chr 6:118,548,296...118,561,716
Ensembl chr 6:118,548,296...118,561,716
JBrowse link
G RNLS renalase, FAD dependent amine oxidase IDA (PMID:15841207) UniProtKB PMID:15841207 NCBI chr10:88,176,052...88,584,480
Ensembl chr10:88,273,864...88,584,530
JBrowse link
G SPTBN4 spectrin beta, non-erythrocytic 4 ISS BHF-UCL GO_REF:0000024 NCBI chr19:40,467,001...40,576,464
Ensembl chr19:40,466,241...40,576,464
JBrowse link
G SPX spexin hormone ISS UniProtKB GO_REF:0000024 NCBI chr12:21,526,296...21,532,947
Ensembl chr12:21,526,296...21,541,249
JBrowse link
G SRI sorcin IMP (PMID:12754254) BHF-UCL PMID:12754254 NCBI chr 7:88,205,115...88,226,976
Ensembl chr 7:88,205,118...88,226,993
Ensembl chr 7:88,205,118...88,226,993
JBrowse link
G TAC1 tachykinin precursor 1 IEA Ensembl GO_REF:0000107 NCBI chr 7:97,732,086...97,740,472
Ensembl chr 7:97,732,084...97,740,472
JBrowse link
G TNF tumor necrosis factor ISO RGD PMID:7875478 RGD:14975128 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
JBrowse link
G TRPV1 transient receptor potential cation channel subfamily V member 1 IEA Ensembl GO_REF:0000107 NCBI chr17:3,565,446...3,609,411
Ensembl chr17:3,565,444...3,609,411
JBrowse link
G UTS2 urotensin 2 ISO RGD PMID:12217424 RGD:2306871 NCBI chr 1:7,846,345...7,913,615
Ensembl chr 1:7,843,083...7,853,512
JBrowse link
negative regulation of heart rate by acetylcholine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CHRM3 cholinergic receptor muscarinic 3 ISO RGD PMID:9316844 RGD:2303391 NCBI chr 1:239,386,565...239,915,450
Ensembl chr 1:239,386,565...239,915,452
JBrowse link
negative regulation of heart rate involved in baroreceptor response to increased systemic arterial blood pressure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADRA1A adrenoceptor alpha 1A IEA Ensembl GO_REF:0000107 NCBI chr 8:26,738,113...26,870,994
Ensembl chr 8:26,748,150...26,867,278
JBrowse link
positive regulation of heart rate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADA adenosine deaminase IEA Ensembl GO_REF:0000107 NCBI chr20:44,619,522...44,651,699
Ensembl chr20:44,619,522...44,652,233
JBrowse link
G ADM adrenomedullin IDA (PMID:18434369) UniProtKB PMID:18434369 NCBI chr11:10,305,073...10,307,397
Ensembl chr11:10,305,073...10,307,397
JBrowse link
G ADM5 adrenomedullin 5 (putative) ISO (PMID:18434369) UniProt PMID:18434369 NCBI chr19:49,688,685...49,690,990
Ensembl chr19:49,688,664...49,690,575
JBrowse link
G ADRA1A adrenoceptor alpha 1A ISO RGD PMID:22040923 RGD:5688308 NCBI chr 8:26,738,113...26,870,994
Ensembl chr 8:26,748,150...26,867,278
JBrowse link
G ADRB1 adrenoceptor beta 1 ISO RGD PMID:9089896 RGD:5129112 NCBI chr10:114,043,866...114,046,904
Ensembl chr10:114,043,866...114,046,904
JBrowse link
G ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 TAS (PMID:22679139) BHF-UCL PMID:22679139 NCBI chr12:110,281,247...110,351,093
Ensembl chr12:110,280,756...110,351,093
JBrowse link
G ATP5PF ATP synthase peripheral stalk subunit F6 IEA Ensembl GO_REF:0000107 NCBI chr21:25,724,500...25,735,653
Ensembl chr21:25,716,503...25,735,673
JBrowse link
G AVPR1A arginine vasopressin receptor 1A IEA Ensembl GO_REF:0000107 NCBI chr12:63,142,759...63,151,201
Ensembl chr12:63,142,759...63,150,942
Ensembl chr12:63,142,759...63,150,942
JBrowse link
G CRHR2 corticotropin releasing hormone receptor 2 ISO RGD PMID:20060787 RGD:5130949 NCBI chr 7:30,649,406...30,700,103
Ensembl chr 7:30,651,942...30,700,129
JBrowse link
G EDN1 endothelin 1 IDA (PMID:2649896) BHF-UCL PMID:2649896 NCBI chr 6:12,256,463...12,297,194
Ensembl chr 6:12,290,361...12,297,194
JBrowse link
G EDN2 endothelin 2 IDA (PMID:2649896) BHF-UCL PMID:2649896 NCBI chr 1:41,478,775...41,484,699
Ensembl chr 1:41,478,775...41,484,683
JBrowse link
G EDN3 endothelin 3 IDA (PMID:2649896) BHF-UCL PMID:2649896 NCBI chr20:59,300,415...59,325,992
Ensembl chr20:59,300,443...59,325,992
JBrowse link
G GCH1 GTP cyclohydrolase 1 IEA Ensembl GO_REF:0000107 NCBI chr14:54,842,016...54,902,826
Ensembl chr14:54,842,008...54,902,826
JBrowse link
G HEY2 hes related family bHLH transcription factor with YRPW motif 2 IEA Ensembl GO_REF:0000107 NCBI chr 6:125,747,639...125,762,243
Ensembl chr 6:125,747,664...125,761,269
JBrowse link
G HRC histidine rich calcium binding protein IGI (PMID:24125847) BHF-UCL PMID:24125847 NCBI chr19:49,151,198...49,155,464
Ensembl chr19:49,151,198...49,155,396
JBrowse link
G KCNQ1 potassium voltage-gated channel subfamily Q member 1 IMP (PMID:19646991) BHF-UCL PMID:19646991 NCBI chr11:2,445,008...2,849,110
Ensembl chr11:2,444,684...2,849,105
Ensembl chr11:2,444,684...2,849,105
JBrowse link
G NMU neuromedin U IEA Ensembl GO_REF:0000107 NCBI chr 4:55,595,231...55,636,793
Ensembl chr 4:55,595,229...55,636,698
JBrowse link
G NPPA natriuretic peptide A IMP (PMID:19646991) BHF-UCL PMID:19646991 NCBI chr 1:11,845,709...11,847,783
Ensembl chr 1:11,845,709...11,848,345
JBrowse link
G RGS4 regulator of G protein signaling 4 IEA Ensembl GO_REF:0000107 NCBI chr 1:163,068,871...163,076,802
Ensembl chr 1:163,068,775...163,076,802
JBrowse link
G RYR2 ryanodine receptor 2 ISS BHF-UCL GO_REF:0000024 NCBI chr 1:237,042,184...237,833,988
Ensembl chr 1:237,042,184...237,833,988
JBrowse link
G SCN3B sodium voltage-gated channel beta subunit 3 ISS BHF-UCL GO_REF:0000024 NCBI chr11:123,629,187...123,654,624
Ensembl chr11:123,629,187...123,655,244
JBrowse link
G SCN5A sodium voltage-gated channel alpha subunit 5 ISO RGD PMID:17259145 RGD:6484226 NCBI chr 3:38,548,061...38,649,687
Ensembl chr 3:38,548,057...38,649,687
Ensembl chr 3:38,548,057...38,649,687
JBrowse link
G SIRT1 sirtuin 1 ISO RGD PMID:22113495 RGD:7240568 NCBI chr10:67,884,656...67,918,390
Ensembl chr10:67,884,656...67,918,390
JBrowse link
G SLC1A1 solute carrier family 1 member 1 IEA Ensembl GO_REF:0000107 NCBI chr 9:4,490,466...4,587,469
Ensembl chr 9:4,490,468...4,587,469
JBrowse link
G TACR3 tachykinin receptor 3 IEA Ensembl GO_REF:0000107 NCBI chr 4:103,586,031...103,719,985
Ensembl chr 4:103,586,031...103,719,985
JBrowse link
G TRPM4 transient receptor potential cation channel subfamily M member 4 ISS BHF-UCL GO_REF:0000024 NCBI chr19:49,157,792...49,211,841
Ensembl chr19:49,157,741...49,211,836
JBrowse link
G UTS2 urotensin 2 ISO RGD PMID:12217424, PMID:18597948 RGD:2306810, RGD:2306871 NCBI chr 1:7,846,345...7,913,615
Ensembl chr 1:7,843,083...7,853,512
JBrowse link
positive regulation of heart rate by epinephrine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TPM1 tropomyosin 1 ISS (PMID:17556658) BHF-UCL PMID:17556658 NCBI chr15:63,042,698...63,071,915
Ensembl chr15:63,042,632...63,071,915
JBrowse link
positive regulation of heart rate by epinephrine-norepinephrine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADRA1A adrenoceptor alpha 1A IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 8:26,738,113...26,870,994
Ensembl chr 8:26,748,150...26,867,278
JBrowse link
G ADRA1B adrenoceptor alpha 1B IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 5:159,916,482...159,989,205
Ensembl chr 5:159,865,080...159,973,012
JBrowse link
G ADRA1D adrenoceptor alpha 1D IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr20:4,220,630...4,249,287
Ensembl chr20:4,220,630...4,249,287
JBrowse link
G ADRB1 adrenoceptor beta 1 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr10:114,043,866...114,046,904
Ensembl chr10:114,043,866...114,046,904
JBrowse link
positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CHRFAM7A CHRNA7 (exons 5-10) and FAM7A (exons A-E) fusion IEA Ensembl GO_REF:0000107 NCBI chr15:30,360,566...30,393,849
Ensembl chr15:30,357,766...30,393,849
Ensembl chr15:30,357,766...30,393,849
JBrowse link
G CHRNA7 cholinergic receptor nicotinic alpha 7 subunit IEA Ensembl GO_REF:0000107 NCBI chr15:32,030,462...32,173,018
Ensembl chr15:31,923,438...32,173,018
JBrowse link
regulation of heart rate by cardiac conduction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKAP9 A-kinase anchoring protein 9 IMP (PMID:18093912) BHF-UCL PMID:18093912 NCBI chr 7:91,940,862...92,112,908
Ensembl chr 7:91,940,867...92,110,673
Ensembl chr 7:91,940,867...92,110,673
JBrowse link
G ANK2 ankyrin 2 ISS
IMP
(PMID:12571597), (PMID:15178757), (PMID:17242276), (PMID:21859974) BHF-UCL PMID:12571597, PMID:15178757, PMID:17242276, PMID:21859974 GO_REF:0000024 NCBI chr 4:112,705,622...113,383,736
Ensembl chr 4:112,818,032...113,384,221
JBrowse link
G BIN1 bridging integrator 1 ISS ARUK-UCL GO_REF:0000024 NCBI chr 2:127,048,023...127,107,154
Ensembl chr 2:127,048,027...127,107,288
JBrowse link
G CACNA1C calcium voltage-gated channel subunit alpha1 C IMP (PMID:15454078), (PMID:15863612), (PMID:17224476), (PMID:26253506) BHF-UCL PMID:15454078, PMID:15863612, PMID:17224476, PMID:26253506 NCBI chr12:1,969,552...2,697,950
Ensembl chr12:1,970,786...2,697,950
JBrowse link
G CACNA1D calcium voltage-gated channel subunit alpha1 D IMP (PMID:21131953) BHF-UCL PMID:21131953 NCBI chr 3:53,494,611...53,813,733
Ensembl chr 3:53,328,963...53,813,733
JBrowse link
G CACNA1G calcium voltage-gated channel subunit alpha1 G ISS BHF-UCL GO_REF:0000024 NCBI chr17:50,560,715...50,629,625
Ensembl chr17:50,560,715...50,627,474
JBrowse link
G CACNA2D1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 IMP (PMID:25527503) BHF-UCL PMID:25527503 NCBI chr 7:81,946,444...82,443,956
Ensembl chr 7:81,946,444...82,443,777
JBrowse link
G CACNB2 calcium voltage-gated channel auxiliary subunit beta 2 IMP (PMID:17224476) BHF-UCL PMID:17224476 NCBI chr10:18,140,424...18,545,881
Ensembl chr10:18,140,677...18,543,557
Ensembl chr10:18,140,677...18,543,557
JBrowse link
G CAMK2D calcium/calmodulin dependent protein kinase II delta IC (PMID:22514276) BHF-UCL PMID:22514276 NCBI chr 4:113,451,032...113,762,177
Ensembl chr 4:113,451,032...113,761,927
JBrowse link
G CAV1 caveolin 1 ISS BHF-UCL GO_REF:0000024 NCBI chr 7:116,525,009...116,561,185
Ensembl chr 7:116,525,001...116,561,184
JBrowse link
G CTNNA3 catenin alpha 3 IMP (PMID:23136403) BHF-UCL PMID:23136403 NCBI chr10:65,912,523...67,696,217
Ensembl chr10:65,912,523...67,696,195
JBrowse link
G DSC2 desmocollin 2 IMP (PMID:23863954) BHF-UCL PMID:23863954 NCBI chr18:31,058,840...31,102,421
Ensembl chr18:31,058,840...31,102,522
JBrowse link
G DSG2 desmoglein 2 IMP (PMID:16505173), (PMID:23381804) BHF-UCL PMID:16505173, PMID:23381804 NCBI chr18:31,498,177...31,549,008
Ensembl chr18:31,498,177...31,549,008
JBrowse link
G DSP desmoplakin IMP (PMID:12373648) BHF-UCL PMID:12373648 NCBI chr 6:7,541,671...7,586,714
Ensembl chr 6:7,541,617...7,586,714
JBrowse link
G GJA5 gap junction protein alpha 5 IEA Ensembl GO_REF:0000107 NCBI chr 1:147,756,199...147,781,127
Ensembl chr 1:147,756,199...147,773,362
JBrowse link
G HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4 IMP (PMID:12750403) BHF-UCL PMID:12750403 NCBI chr15:73,319,859...73,368,958
Ensembl chr15:73,319,859...73,368,958
JBrowse link
G JUP junction plakoglobin IMP (PMID:17924338) BHF-UCL PMID:17924338 NCBI chr17:41,754,608...41,786,711
Ensembl chr17:41,754,604...41,786,931
JBrowse link
G KCNA5 potassium voltage-gated channel subfamily A member 5 IMP (PMID:19343045), (PMID:23264583) BHF-UCL PMID:19343045, PMID:23264583 NCBI chr12:5,043,879...5,046,788
Ensembl chr12:5,043,879...5,046,788
JBrowse link
G KCND3 potassium voltage-gated channel subfamily D member 3 IMP (PMID:21349352) BHF-UCL PMID:21349352 NCBI chr 1:111,770,662...111,989,668
Ensembl chr 1:111,770,662...111,989,155
JBrowse link
G KCNE1 potassium voltage-gated channel subfamily E regulatory subunit 1 IMP
IBA
(PMID:10400998)
(PMID:21873635)
BHF-UCL
GO_Central
PMID:10400998, PMID:21873635 NCBI chr21:34,446,688...34,512,210
Ensembl chr21:34,446,688...34,512,210
JBrowse link
G KCNE1B potassium voltage-gated channel subfamily E regulatory subunit 1B IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr21:7,816,677...7,829,632
Ensembl chr21:7,816,675...7,829,926
JBrowse link
G KCNE2 potassium voltage-gated channel subfamily E regulatory subunit 2 IMP
IBA
(PMID:10219239)
(PMID:21873635)
BHF-UCL
GO_Central
PMID:10219239, PMID:21873635 NCBI chr21:34,364,006...34,371,381
Ensembl chr21:34,364,024...34,371,389
JBrowse link
G KCNE3 potassium voltage-gated channel subfamily E regulatory subunit 3 IMP
IBA
(PMID:22987075)
(PMID:21873635)
BHF-UCL
GO_Central
PMID:21873635, PMID:22987075 NCBI chr11:74,454,841...74,467,729
Ensembl chr11:74,454,841...74,467,729
JBrowse link
G KCNE4 potassium voltage-gated channel subfamily E regulatory subunit 4 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 2:223,052,190...223,055,637
Ensembl chr 2:223,051,814...223,198,399
JBrowse link
G KCNE5 potassium voltage-gated channel subfamily E regulatory subunit 5 IMP
IBA
(PMID:18313602), (PMID:21493962)
(PMID:21873635)
BHF-UCL
GO_Central
PMID:18313602, PMID:21493962, PMID:21873635 NCBI chr  X:109,623,700...109,625,172
Ensembl chr  X:109,623,700...109,625,172
JBrowse link
G KCNH2 potassium voltage-gated channel subfamily H member 2 IMP
IBA
(PMID:21536673), (PMID:7889573)
(PMID:21873635)
BHF-UCL
GO_Central
PMID:7889573, PMID:21536673, PMID:21873635 NCBI chr 7:150,944,956...150,978,321
Ensembl chr 7:150,944,961...150,978,321
JBrowse link
G KCNH6 potassium voltage-gated channel subfamily H member 6 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr17:63,523,334...63,548,992
Ensembl chr17:63,523,334...63,548,977
JBrowse link
G KCNJ2 potassium inwardly rectifying channel subfamily J member 2 IMP (PMID:15761194) BHF-UCL PMID:15761194 NCBI chr17:70,169,532...70,180,044
Ensembl chr17:70,168,673...70,180,044
Ensembl chr17:70,168,673...70,180,044
JBrowse link
G KCNJ3 potassium inwardly rectifying channel subfamily J member 3 IC (PMID:20560207) BHF-UCL PMID:20560207 NCBI chr 2:154,698,695...154,858,354
Ensembl chr 2:154,697,855...154,858,354
JBrowse link
G KCNJ5 potassium inwardly rectifying channel subfamily J member 5 IMP (PMID:20560207) BHF-UCL PMID:20560207 NCBI chr11:128,891,356...128,921,163
Ensembl chr11:128,891,356...128,921,163
JBrowse link
G KCNQ1 potassium voltage-gated channel subfamily Q member 1 IMP (PMID:8528244) BHF-UCL PMID:8528244 NCBI chr11:2,445,008...2,849,110
Ensembl chr11:2,444,684...2,849,105
Ensembl chr11:2,444,684...2,849,105
JBrowse link
G PKP2 plakophilin 2 IMP (PMID:17980246), (PMID:22889254) BHF-UCL PMID:17980246, PMID:22889254 NCBI chr12:32,790,755...32,896,777
Ensembl chr12:32,790,745...32,896,840
Ensembl chr12:32,790,745...32,896,840
JBrowse link
G RBFOX2 RNA binding fox-1 homolog 2 ISO (MGI:MGI:6402838|PMID:32109384) MGI PMID:32109384 MGI:MGI:6402838 NCBI chr22:35,738,736...36,028,892
Ensembl chr22:35,738,736...36,028,824
JBrowse link
G SCN1B sodium voltage-gated channel beta subunit 1 IMP
IBA
(PMID:19808477)
(PMID:21873635)
BHF-UCL
GO_Central
PMID:19808477, PMID:21873635 NCBI chr19:35,030,470...35,040,449
Ensembl chr19:35,030,470...35,040,449
JBrowse link
G SCN2B sodium voltage-gated channel beta subunit 2 IMP (PMID:19808477) BHF-UCL PMID:19808477 NCBI chr11:118,162,806...118,176,639
Ensembl chr11:118,157,849...118,176,639
Ensembl chr11:118,157,849...118,176,639
JBrowse link
G SCN3B sodium voltage-gated channel beta subunit 3 IMP
IBA
(PMID:20042427), (PMID:21051419)
(PMID:21873635)
BHF-UCL
GO_Central
PMID:20042427, PMID:21051419, PMID:21873635 NCBI chr11:123,629,187...123,654,624
Ensembl chr11:123,629,187...123,655,244
JBrowse link
G SCN4B sodium voltage-gated channel beta subunit 4 IMP (PMID:17592081) BHF-UCL PMID:17592081 NCBI chr11:118,133,377...118,152,823
Ensembl chr11:118,133,377...118,152,888
JBrowse link
G SCN5A sodium voltage-gated channel alpha subunit 5 IMP (PMID:21895525) BHF-UCL PMID:21895525 NCBI chr 3:38,548,061...38,649,687
Ensembl chr 3:38,548,057...38,649,687
Ensembl chr 3:38,548,057...38,649,687
JBrowse link
G TRPM4 transient receptor potential cation channel subfamily M member 4 IMP (PMID:27207958) BHF-UCL PMID:27207958 NCBI chr19:49,157,792...49,211,841
Ensembl chr19:49,157,741...49,211,836
JBrowse link
G YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon IC (PMID:11953308) BHF-UCL PMID:11953308 NCBI chr17:1,344,275...1,400,229
Ensembl chr17:1,344,275...1,400,222
JBrowse link
regulation of heart rate by chemical signal term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FFAR3 free fatty acid receptor 3 ISO (MGI:MGI:5009064|PMID:21518883) MGI PMID:21518883 MGI:MGI:5009064 NCBI chr19:35,358,106...35,360,491
Ensembl chr19:35,358,460...35,360,489
JBrowse link
G NOS1AP nitric oxide synthase 1 adaptor protein IMP (PMID:19247217) BHF-UCL PMID:19247217 NCBI chr 1:162,069,691...162,370,475
Ensembl chr 1:162,069,691...162,370,475
JBrowse link
G SREBF1 sterol regulatory element binding transcription factor 1 IEA Ensembl GO_REF:0000107 NCBI chr17:17,811,334...17,837,017
Ensembl chr17:17,810,399...17,837,011
JBrowse link
regulation of heart rate by hormone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KCNH2 potassium voltage-gated channel subfamily H member 2 TAS (PMID:11953308) BHF-UCL PMID:11953308 NCBI chr 7:150,944,956...150,978,321
Ensembl chr 7:150,944,961...150,978,321
JBrowse link
G YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon NAS (PMID:11953308) BHF-UCL PMID:11953308 NCBI chr17:1,344,275...1,400,229
Ensembl chr17:1,344,275...1,400,222
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18626
    biological regulation 13272
      regulation of biological quality 4603
        regulation of heart rate 117
          circadian regulation of heart rate + 0
          modulation of heart rate in other organism + 0
          negative regulation of heart rate + 15
          positive regulation of heart rate + 33
          regulation of heart rate by cardiac conduction 40
          regulation of heart rate by chemical signal + 8
Path 2
Term Annotations click to browse term
  biological_process 18626
    multicellular organismal process 8777
      system process 2666
        circulatory system process 717
          blood circulation 635
            heart contraction 317
              regulation of heart contraction 279
                regulation of heart rate 117
                  circadian regulation of heart rate + 0
                  modulation of heart rate in other organism + 0
                  negative regulation of heart rate + 15
                  positive regulation of heart rate + 33
                  regulation of heart rate by cardiac conduction 40
                  regulation of heart rate by chemical signal + 8
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.