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ONTOLOGY REPORT - ANNOTATIONS


Term:G protein-coupled receptor internalization
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Accession:GO:0002031 term browser browse the term
Definition:The process that results in the uptake of a G protein-coupled receptor into an endocytic vesicle.


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G protein-coupled receptor internalization term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adm adrenomedullin ISO (PMID:10882736) RGD PMID:10882736 NCBI chr 1:175,443,189...175,447,260
Ensembl chr 1:175,445,088...175,447,259
JBrowse link
G Arr3 arrestin 3 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:70,438,590...70,452,140
Ensembl chr  X:70,438,617...70,452,067
JBrowse link
G Arrb1 arrestin, beta 1 ISO
IBA
(PMID:10521508), (PMID:12582207)
PMID:21873635
RGD PMID:10521508, PMID:12582207, PMID:21873635 RGD:13792537 NCBI chr 1:164,502,099...164,573,947
Ensembl chr 1:164,502,389...164,593,139
JBrowse link
G Arrb2 arrestin, beta 2 ISO
IBA
(PMID:10644702), (PMID:12582207)
PMID:21873635
RGD PMID:10644702, PMID:12582207, PMID:21873635 RGD:13792537 NCBI chr10:57,040,252...57,048,045
Ensembl chr10:57,040,267...57,048,134
JBrowse link
G Calca calcitonin-related polypeptide alpha ISO (PMID:10882736) RGD PMID:10882736 NCBI chr 1:184,184,018...184,188,922
Ensembl chr 1:184,184,020...184,188,911
JBrowse link
G Dnm1 dynamin 1 IMP RGD PMID:14709338 RGD:9685157 NCBI chr 3:11,338,081...11,382,043
Ensembl chr 3:11,338,083...11,382,043
JBrowse link
G Dnm2 dynamin 2 IMP RGD PMID:14709338 RGD:9685157 NCBI chr 8:22,458,869...22,540,649
Ensembl chr 8:22,458,899...22,540,524
JBrowse link
G Drd2 dopamine receptor D2 IDA RGD PMID:14617818 RGD:1581465 NCBI chr 8:53,678,777...53,743,643
Ensembl chr 8:53,678,777...53,743,642
JBrowse link
G Drd3 dopamine receptor D3 IDA
ISO
(PMID:18424554) RGD PMID:18424554, PMID:14617818 RGD:1581465 NCBI chr11:61,819,102...61,883,223
Ensembl chr11:61,822,077...61,874,327
JBrowse link
G Grk4 G protein-coupled receptor kinase 4 IMP RGD PMID:12519791 RGD:1304268 NCBI chr14:81,261,708...81,339,516
Ensembl chr14:81,265,672...81,339,526
JBrowse link
G Htr1b 5-hydroxytryptamine receptor 1B ISO (MGI:MGI:4821070|PMID:17325130) RGD PMID:17325130 MGI:MGI:4821070 NCBI chr 8:89,113,984...89,130,830
Ensembl chr 8:89,129,453...89,130,991
JBrowse link
G Htr2b 5-hydroxytryptamine receptor 2B IEA
ISO
GO_REF:0000107
(MGI:MGI:4821070|PMID:17325130)
Ensembl
RGD
PMID:17325130 GO_REF:0000107, MGI:MGI:4821070 NCBI chr 9:93,112,781...93,130,135
Ensembl chr 9:93,112,805...93,125,014
JBrowse link
G Pld2 phospholipase D2 ISO (MGI:MGI:3042801|PMID:14718562) RGD PMID:14718562 MGI:MGI:3042801 NCBI chr10:57,161,921...57,181,148
Ensembl chr10:57,163,174...57,179,730
JBrowse link
G Sag S-antigen visual arrestin IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:94,926,901...94,972,162
Ensembl chr 9:94,928,489...94,972,027
JBrowse link
negative regulation of G protein-coupled receptor internalization term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Necab2 N-terminal EF-hand calcium binding protein 2 ISO (PMID:17689978) RGD PMID:17689978 NCBI chr19:52,086,325...52,112,633
Ensembl chr19:52,086,325...52,112,629
JBrowse link
G Ubqln2 ubiquilin 2 ISO (PMID:18199683) RGD PMID:18199683 NCBI chr  X:18,723,313...18,726,732
Ensembl chr  X:18,723,341...18,726,732
JBrowse link
positive regulation of G protein-coupled receptor internalization term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apln apelin IDA
ISO
PMID:11359874
(MGI:MGI:5902690|PMID:11359874)
(PMID:11359874)
RGD PMID:11359874, PMID:11359874 MGI:MGI:5902690, RGD:12907555 NCBI chr  X:134,856,719...134,866,210
Ensembl chr  X:134,856,726...134,866,210
JBrowse link
G App amyloid beta precursor protein ISO (PMID:18723082) RGD PMID:18723082 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858
JBrowse link
prostaglandin receptor internalization term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptger3 prostaglandin E receptor 3 IMP RGD PMID:15937517 RGD:10043344 NCBI chr 2:263,895,093...263,979,682
Ensembl chr 2:263,895,241...263,979,698
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20027
    cellular process 18798
      signal transduction 7011
        negative regulation of signal transduction 1235
          negative adaptation of signaling pathway 30
            desensitization of G protein-coupled receptor signaling pathway 30
              G protein-coupled receptor internalization 19
                negative regulation of G protein-coupled receptor internalization 2
                positive regulation of G protein-coupled receptor internalization 2
                prostaglandin receptor internalization 1
                regulation of G protein-coupled receptor internalization + 4
Path 2
Term Annotations click to browse term
  biological_process 20027
    biological regulation 13773
      regulation of biological process 13075
        regulation of cellular process 12561
          signal transduction 7011
            regulation of signal transduction 2934
              negative regulation of signal transduction 1235
                negative adaptation of signaling pathway 30
                  desensitization of G protein-coupled receptor signaling pathway 30
                    G protein-coupled receptor internalization 19
                      negative regulation of G protein-coupled receptor internalization 2
                      positive regulation of G protein-coupled receptor internalization 2
                      prostaglandin receptor internalization 1
                      regulation of G protein-coupled receptor internalization + 4
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.