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ONTOLOGY REPORT - ANNOTATIONS


Term:chondrocyte differentiation
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Accession:GO:0002062 term browser browse the term
Definition:The process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte. A chondrocyte is a polymorphic cell that forms cartilage.


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chondrocyte differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arid5a AT-rich interaction domain 5A JBrowse link 9 42,871,907 42,886,725 RGD:1624291
G Bmp2 bone morphogenetic protein 2 JBrowse link 3 126,335,963 126,346,771 RGD:1624291
RGD:1600115
G Bmp4 bone morphogenetic protein 4 JBrowse link 15 20,776,060 20,791,013 RGD:1600115
RGD:1624291
G Bmpr1a bone morphogenetic protein receptor type 1A JBrowse link 16 10,758,278 10,852,170 RGD:1624291
RGD:1600115
G Bmpr1b bone morphogenetic protein receptor type 1B JBrowse link 2 247,392,195 247,662,026 RGD:1624291
RGD:1600115
G Ccn3 cellular communication network factor 3 JBrowse link 7 94,375,134 94,382,154 RGD:10400852
RGD:1600115
RGD:1624291
G Col11a2 collagen type XI alpha 2 chain JBrowse link 20 3,829,324 3,859,022 RGD:1624291
RGD:1600115
G Col2a1 collagen type II alpha 1 chain JBrowse link 7 139,454,945 139,484,403 RGD:5134342
RGD:1624291
RGD:1600115
G Col9a1 collagen type IX alpha 1 chain JBrowse link 9 30,419,001 30,502,307 RGD:1600950
G Creb3l2 cAMP responsive element binding protein 3-like 2 JBrowse link 4 64,869,285 64,981,519 RGD:1624291
RGD:1600115
G Cst5 cystatin D JBrowse link 3 144,569,502 144,574,112 RGD:1624291
G Cytl1 cytokine like 1 JBrowse link 14 77,805,137 77,810,147 RGD:1624291
RGD:1600115
G Fgf9 fibroblast growth factor 9 JBrowse link 15 38,341,657 38,386,945 RGD:1624291
RGD:1600115
G Fgfr1 Fibroblast growth factor receptor 1 JBrowse link 16 71,265,390 71,319,046 RGD:1624291
RGD:1600115
G Gli2 GLI family zinc finger 2 JBrowse link 13 34,829,021 35,049,172 RGD:1624291
G Gpld1 glycosylphosphatidylinositol specific phospholipase D1 JBrowse link 17 42,085,027 42,131,344 RGD:1624291
RGD:1600115
G Hes5 hes family bHLH transcription factor 5 JBrowse link 5 172,364,421 172,365,188 RGD:1624291
RGD:1600115
G Hmga2 high mobility group AT-hook 2 JBrowse link 7 65,159,944 65,275,408 RGD:1624291
RGD:1600115
G Hspg2 heparan sulfate proteoglycan 2 JBrowse link 5 155,812,096 155,913,751 RGD:1624291
G Ift80 intraflagellar transport 80 JBrowse link 2 165,506,878 165,600,748 RGD:1624291
RGD:1600115
G Mapk14 mitogen activated protein kinase 14 JBrowse link 20 5,933,290 5,995,137 RGD:1600115
RGD:1624291
G Matn1 matrilin 1 JBrowse link 5 149,077,412 149,086,957 RGD:1624291
G Mef2c myocyte enhancer factor 2C JBrowse link 2 11,658,534 11,822,788 RGD:1624291
RGD:1600115
G Mef2d myocyte enhancer factor 2D JBrowse link 2 187,511,775 187,541,285 RGD:1624291
RGD:1600115
G Mustn1 musculoskeletal, embryonic nuclear protein 1 JBrowse link 16 6,962,737 6,964,987 RGD:1600115
G Nfib nuclear factor I/B JBrowse link 5 100,436,343 100,647,962 RGD:1624291
RGD:1600115
G Osr1 odd-skipped related transcription factor 1 JBrowse link 6 35,314,431 35,321,458 RGD:1624291
RGD:1600115
G Osr2 odd-skipped related transciption factor 2 JBrowse link 7 74,047,820 74,055,096 RGD:1624291
RGD:1600115
G Prkca protein kinase C, alpha JBrowse link 10 96,186,509 96,585,168 RGD:1624291
G Pth1r parathyroid hormone 1 receptor JBrowse link 8 118,984,531 119,012,803 RGD:1624291
RGD:1600115
G Runx1 RUNX family transcription factor 1 JBrowse link 11 32,765,147 33,003,061 RGD:13792537
G Runx2 RUNX family transcription factor 2 JBrowse link 9 18,564,743 18,773,092 RGD:1624291
RGD:13792537
G Runx3 RUNX family transcription factor 3 JBrowse link 5 153,507,093 153,531,137 RGD:1624291
RGD:13792537
G Scx scleraxis bHLH transcription factor JBrowse link 7 117,519,075 117,521,093 RGD:1624291
RGD:1600115
G Shox2 short stature homeobox 2 JBrowse link 2 164,118,175 164,126,783 RGD:1624291
G Six2 SIX homeobox 2 JBrowse link 6 8,952,572 8,955,893 RGD:1624291
RGD:1600115
G Snx19 sorting nexin 19 JBrowse link 8 31,497,034 31,534,077 RGD:1624291
RGD:1600115
G Sox9 SRY-box transcription factor 9 JBrowse link 10 101,288,528 101,294,030 RGD:1624291
RGD:13792537
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:1624291
RGD:1600115
G Tgfbi transforming growth factor, beta induced JBrowse link 17 8,400,123 8,429,338 RGD:1599388
G Trps1 transcriptional repressor GATA binding 1 JBrowse link 7 90,085,895 90,320,430 RGD:1624291
G Wnt10b Wnt family member 10B JBrowse link 7 140,448,284 140,466,159 RGD:1624291
RGD:1600115
G Wnt2b Wnt family member 2B JBrowse link 2 207,433,771 207,457,094 RGD:1624291
RGD:1600115
G Wnt5b Wnt family member 5B JBrowse link 4 151,500,962 151,516,894 RGD:1624291
RGD:1600115
G Wnt7a Wnt family member 7A JBrowse link 4 122,994,425 123,040,609 RGD:1624291
RGD:1600115
chondrocyte development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acan aggrecan JBrowse link 1 140,762,758 140,824,441 RGD:1624291
RGD:1600115
G Bmpr2 bone morphogenetic protein receptor type 2 JBrowse link 9 66,568,074 66,683,019 RGD:1624291
RGD:1600115
G Chst11 carbohydrate sulfotransferase 11 JBrowse link 7 26,641,856 26,890,503 RGD:1624291
RGD:1600115
G Chsy1 chondroitin sulfate synthase 1 JBrowse link 1 127,010,587 127,071,570 RGD:1624291
RGD:1600115
G Col11a1 collagen type XI alpha 1 chain JBrowse link 2 216,863,423 217,056,523 RGD:1624291
RGD:1600115
G Comp cartilage oligomeric matrix protein JBrowse link 16 20,798,437 20,807,070 RGD:1624291
RGD:1600115
G Ecm1 extracellular matrix protein 1 JBrowse link 2 197,855,468 197,860,973 RGD:1624291
RGD:1600115
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 JBrowse link 4 98,648,513 98,709,695 RGD:1624291
G Fgf18 fibroblast growth factor 18 JBrowse link 10 18,047,109 18,082,290 RGD:1624291
RGD:1600115
G Impad1 inositol monophosphatase domain containing 1 JBrowse link 17 90,191,119 90,218,013 RGD:1624291
G Mia3 MIA SH3 domain ER export factor 3 JBrowse link 13 101,727,434 101,770,127 RGD:1624291
G Msx2 msh homeobox 2 JBrowse link 17 11,683,862 11,689,527 RGD:1624291
RGD:1600115
G Rarg retinoic acid receptor, gamma JBrowse link 7 143,840,739 143,863,206 RGD:1624291
G Runx2 RUNX family transcription factor 2 JBrowse link 9 18,564,743 18,773,092 RGD:1624291
RGD:1600115
G Sfrp2 secreted frizzled-related protein 2 JBrowse link 2 182,723,732 182,731,277 RGD:1624291
RGD:1600115
G Shox2 short stature homeobox 2 JBrowse link 2 164,118,175 164,126,783 RGD:1624291
G Smpd3 sphingomyelin phosphodiesterase 3 JBrowse link 19 38,237,963 38,321,572 RGD:1624291
G Sox9 SRY-box transcription factor 9 JBrowse link 10 101,288,528 101,294,030 RGD:1624291
G Sulf1 sulfatase 1 JBrowse link 5 5,999,520 6,186,901 RGD:1624291
RGD:1600115
G Sulf2 sulfatase 2 JBrowse link 3 162,791,349 162,872,984 RGD:1624291
RGD:1600115
chondrocyte development involved in endochondral bone morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Serpinh1 serpin family H member 1 JBrowse link 1 164,301,010 164,308,306 RGD:1624291
RGD:1600115
G Smpd3 sphingomyelin phosphodiesterase 3 JBrowse link 19 38,237,963 38,321,572 RGD:1624291
RGD:1600115
chondrocyte differentiation involved in endochondral bone morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Axin2 axin 2 JBrowse link 10 97,212,483 97,238,824 RGD:1624291
RGD:1600115
G Ihh Indian hedgehog signaling molecule JBrowse link 9 82,208,223 82,214,440 RGD:1624291
RGD:1600115
G Scube2 signal peptide, CUB domain and EGF like domain containing 2 JBrowse link 1 174,428,056 174,495,356 RGD:1624291
G Sox9 SRY-box transcription factor 9 JBrowse link 10 101,288,528 101,294,030 RGD:1624291
RGD:1600115
G Trip11 thyroid hormone receptor interactor 11 JBrowse link 6 125,741,520 125,812,926 RGD:1624291
RGD:1600115
chondrocyte hypertrophy term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mex3c mex-3 RNA binding family member C JBrowse link 18 69,549,937 69,571,736 RGD:1624291
G Sox9 SRY-box transcription factor 9 JBrowse link 10 101,288,528 101,294,030 RGD:1624291
RGD:1600115
growth plate cartilage chondrocyte development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Col27a1 collagen type XXVII alpha 1 chain JBrowse link 5 79,054,004 79,172,442 RGD:1624291
RGD:1600115
G Poc1a POC1 centriolar protein A JBrowse link 8 114,982,764 115,050,844 RGD:1624291
RGD:1600115
growth plate cartilage chondrocyte differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Anxa6 annexin A6 JBrowse link 10 40,320,581 40,375,605 RGD:13792537
G Nppc natriuretic peptide C JBrowse link 9 93,731,436 93,735,636 RGD:1624291
RGD:1600115
growth plate cartilage chondrocyte growth term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Rarg retinoic acid receptor, gamma JBrowse link 7 143,840,739 143,863,206 RGD:1624291
RGD:1600115
G Tgfbr2 transforming growth factor, beta receptor 2 JBrowse link 8 124,310,288 124,399,345 RGD:1624291
RGD:1600115
growth plate cartilage chondrocyte morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Coch cochlin JBrowse link 6 72,359,702 72,373,710 RGD:13792537
G Col12a1 collagen type XII alpha 1 chain JBrowse link 8 87,042,820 87,150,701 RGD:13792537
G Col14a1 collagen type XIV alpha 1 chain JBrowse link 7 95,054,877 95,274,073 RGD:13792537
G Col20a1 collagen type XX alpha 1 chain JBrowse link 3 176,491,292 176,526,009 RGD:13792537
G Col6a2 collagen type VI alpha 2 chain JBrowse link 20 12,773,472 12,801,179 RGD:13792537
G Col7a1 collagen type VII alpha 1 chain JBrowse link 8 117,694,441 117,726,844 RGD:13792537
G LOC100911854 mannose-binding protein C-like JBrowse link 1 248,723,370 248,730,969 RGD:13792537
G Matn1 matrilin 1 JBrowse link 5 149,077,412 149,086,957 RGD:1624291
RGD:13792537
G Matn2 matrilin 2 JBrowse link 7 72,985,832 73,210,093 RGD:13792537
G Matn3 matrilin 3 JBrowse link 6 34,071,428 34,091,048 RGD:13792537
G Matn4 matrilin 4 JBrowse link 3 160,838,632 160,853,650 RGD:13792537
G Mbl1 mannose-binding lectin (protein A) 1 JBrowse link 16 18,736,154 18,742,193 RGD:13792537
G Mbl2 mannose binding lectin 2 JBrowse link 1 248,435,069 248,442,669 RGD:13792537
G Vit vitrin JBrowse link 6 1,091,817 1,208,888 RGD:13792537
G Vwa1 von Willebrand factor A domain containing 1 JBrowse link 5 173,216,737 173,221,923 RGD:13792537
G Vwa2 von Willebrand factor A domain containing 2 JBrowse link 1 277,689,478 277,730,407 RGD:13792537
negative regulation of chondrocyte development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pthlh parathyroid hormone-like hormone JBrowse link 4 181,663,425 181,674,181 RGD:1624291
G Rflna refilin A JBrowse link 12 37,038,732 37,047,628 RGD:1624291
RGD:13792537
G Rflnb refilin B JBrowse link 10 64,196,103 64,202,380 RGD:1624291
RGD:13792537
negative regulation of chondrocyte differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adamts12 ADAM metallopeptidase with thrombospondin type 1 motif, 12 JBrowse link 2 61,039,072 61,340,687 RGD:1624291
RGD:1600115
G Adamts7 ADAM metallopeptidase with thrombospondin type 1 motif, 7 JBrowse link 8 97,535,777 97,575,661 RGD:1624291
RGD:1600115
G Bmp4 bone morphogenetic protein 4 JBrowse link 15 20,776,060 20,791,013 RGD:1624291
RGD:1600115
G Ccn4 cellular communication network factor 4 JBrowse link 7 107,695,227 107,723,759 RGD:1600115
RGD:1624291
G Chadl chondroadherin-like JBrowse link 7 122,915,847 122,929,127 RGD:1624291
RGD:1600115
G Ctnnb1 catenin beta 1 JBrowse link 8 129,601,511 129,628,378 RGD:1624291
RGD:1600115
G Efemp1 EGF containing fibulin extracellular matrix protein 1 JBrowse link 14 113,202,382 113,294,993 RGD:1600115
RGD:1624291
G Gdf5 growth differentiation factor 5 JBrowse link 3 151,482,672 151,487,129 RGD:1624291
RGD:1600115
G Gli2 GLI family zinc finger 2 JBrowse link 13 34,829,021 35,049,172 RGD:1624291
G Grem1 gremlin 1, DAN family BMP antagonist JBrowse link 3 105,203,309 105,214,989 RGD:1624291
RGD:1600115
G Ltbp3 latent transforming growth factor beta binding protein 3 JBrowse link 1 221,099,155 221,116,096 RGD:1624291
RGD:1600115
G Nkx3-2 NK3 homeobox 2 JBrowse link 14 73,813,531 73,818,489 RGD:1624291
G Pth parathyroid hormone JBrowse link 1 178,215,829 178,218,761 RGD:12793028
G Pthlh parathyroid hormone-like hormone JBrowse link 4 181,663,425 181,674,181 RGD:1624291
G Rarb retinoic acid receptor, beta JBrowse link 15 9,915,223 10,262,599 RGD:1624291
RGD:1600115
G Rarg retinoic acid receptor, gamma JBrowse link 7 143,840,739 143,863,206 RGD:1624291
RGD:1600115
G Snai2 snail family transcriptional repressor 2 JBrowse link 11 90,404,421 90,406,730 RGD:1624291
G Sox9 SRY-box transcription factor 9 JBrowse link 10 101,288,528 101,294,030 RGD:1624291
RGD:1600115
G Tgfbr1 transforming growth factor, beta receptor 1 JBrowse link 5 63,056,071 63,119,635 RGD:1624291
G Wnt9a Wnt family member 9A JBrowse link 10 45,659,045 45,686,103 RGD:1624291
positive regulation of chondrocyte differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Anxa2 annexin A2 JBrowse link 8 75,687,134 75,723,589 RGD:13792537
G Anxa9 annexin A9 JBrowse link 2 196,470,318 196,481,568 RGD:13792537
G Bmp6 bone morphogenetic protein 6 JBrowse link 17 26,955,142 27,112,820 RGD:7242190
G Fgf18 fibroblast growth factor 18 JBrowse link 10 18,047,109 18,082,290 RGD:1624291
RGD:1600115
G Gdf5 growth differentiation factor 5 JBrowse link 3 151,482,672 151,487,129 RGD:1624291
RGD:1600115
G Gdf6 growth differentiation factor 6 JBrowse link 5 23,056,345 23,072,666 RGD:1624291
RGD:1600115
G Gli3 GLI family zinc finger 3 JBrowse link 17 52,294,942 52,569,036 RGD:1624291
RGD:1600115
G Hoxa11 homeobox A11 JBrowse link 4 82,296,888 82,301,419 RGD:1624291
G Hoxd11 homeobox D11 JBrowse link 3 61,604,256 61,606,874 RGD:1624291
G Loxl2 lysyl oxidase-like 2 JBrowse link 15 51,276,022 51,365,238 RGD:1600115
RGD:1624291
G Mustn1 musculoskeletal, embryonic nuclear protein 1 JBrowse link 16 6,962,737 6,964,987 RGD:1624291
RGD:1600115
G Pkdcc protein kinase domain containing, cytoplasmic JBrowse link 6 6,427,657 6,436,974 RGD:1624291
G Por cytochrome p450 oxidoreductase JBrowse link 12 23,998,411 24,017,063 RGD:2316785
G Rela RELA proto-oncogene, NF-kB subunit JBrowse link 1 220,992,770 221,003,249 RGD:2298851
G Runx2 RUNX family transcription factor 2 JBrowse link 9 18,564,743 18,773,092 RGD:1624291
RGD:1600115
G Smad3 SMAD family member 3 JBrowse link 8 68,569,530 68,678,349 RGD:1624291
RGD:1600115
G Sox5 SRY-box transcription factor 5 JBrowse link 4 178,062,267 179,031,991 RGD:1624291
RGD:13792537
G Sox6 SRY-box transcription factor 6 JBrowse link 1 185,631,702 186,186,192 RGD:1624291
RGD:13792537
G Sox9 SRY-box transcription factor 9 JBrowse link 10 101,288,528 101,294,030 RGD:1600115
RGD:13792537
RGD:1624291
G Thrb thyroid hormone receptor beta JBrowse link 15 8,890,578 9,239,815 RGD:1601663
G Zbtb16 zinc finger and BTB domain containing 16 JBrowse link 8 52,980,226 53,146,765 RGD:1624291
RGD:1600115
G Zfp219 zinc finger protein 219 JBrowse link 15 28,402,412 28,417,379 RGD:1600115
RGD:1624291
regulation of chondrocyte development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Axin2 axin 2 JBrowse link 10 97,212,483 97,238,824 RGD:1624291
RGD:1600115
regulation of chondrocyte differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ccn2 cellular communication network factor 2 JBrowse link 1 21,851,657 21,854,773 RGD:1624291
RGD:1600115
G Glg1 golgi glycoprotein 1 JBrowse link 19 42,983,879 43,088,074 RGD:1624291
RGD:1600115
G Hoxa11 homeobox A11 JBrowse link 4 82,296,888 82,301,419 RGD:1624291
G Hoxd11 homeobox D11 JBrowse link 3 61,604,256 61,606,874 RGD:1624291
G Lnpk lunapark, ER junction formation factor JBrowse link 3 61,432,128 61,494,828 RGD:1624291
RGD:1600115
G Maf MAF bZIP transcription factor JBrowse link 19 48,179,826 48,200,995 RGD:1624291
RGD:1600115
G Mdk midkine JBrowse link 3 80,841,003 80,843,895 RGD:1600115
RGD:1624291
G Shox2 short stature homeobox 2 JBrowse link 2 164,118,175 164,126,783 RGD:1624291
G Six2 SIX homeobox 2 JBrowse link 6 8,952,572 8,955,893 RGD:1624291
RGD:1600115
G Trps1 transcriptional repressor GATA binding 1 JBrowse link 7 90,085,895 90,320,430 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19245
    cellular process 17125
      cellular developmental process 4400
        cell differentiation 4180
          chondrocyte differentiation 128
            chondrocyte development + 45
            chondrocyte differentiation involved in endochondral bone morphogenesis + 29
            negative regulation of chondrocyte differentiation + 22
            positive regulation of chondrocyte differentiation + 22
            regulation of chondrocyte differentiation + 51
Path 2
Term Annotations click to browse term
  biological_process 19245
    developmental process 6597
      anatomical structure development 6063
        multicellular organism development 5534
          system development 5081
            animal organ development 3881
              cartilage development 220
                chondrocyte differentiation 128
                  chondrocyte development + 45
                  chondrocyte differentiation involved in endochondral bone morphogenesis + 29
                  negative regulation of chondrocyte differentiation + 22
                  positive regulation of chondrocyte differentiation + 22
                  regulation of chondrocyte differentiation + 51
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.