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ONTOLOGY REPORT - ANNOTATIONS


Term:chondrocyte differentiation
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Accession:GO:0002062 term browser browse the term
Definition:The process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte. A chondrocyte is a polymorphic cell that forms cartilage.


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chondrocyte differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arid5a AT-rich interaction domain 5A JBrowse link NW_004955470 3,951,010 3,964,391 RGD:9068941
G Bmp2 bone morphogenetic protein 2 JBrowse link NW_004955415 17,048,374 17,058,172 RGD:9068941
G Bmp4 bone morphogenetic protein 4 JBrowse link NW_004955409 9,432,835 9,439,680 RGD:9068941
G Bmpr1a bone morphogenetic protein receptor type 1A JBrowse link NW_004955510 5,812,571 5,936,312 RGD:9068941
G Bmpr1b bone morphogenetic protein receptor type 1B JBrowse link NW_004955405 5,408,171 5,784,930 RGD:9068941
G Ccn3 cellular communication network factor 3 JBrowse link NW_004955417 25,218,613 25,225,755 RGD:9068941
G Col11a2 collagen type XI alpha 2 chain JBrowse link NW_004955437 1,739,426 1,767,087 RGD:9068941
G Col2a1 collagen type II alpha 1 chain JBrowse link NW_004955500 6,860,771 6,885,466 RGD:9068941
G Col9a1 collagen type IX alpha 1 chain JBrowse link NW_004955488 5,296,895 5,384,940 RGD:9068941
G Creb3l2 cAMP responsive element binding protein 3 like 2 JBrowse link NW_004955494 5,014,509 5,094,220 RGD:9068941
G Cytl1 cytokine like 1 JBrowse link NW_004955514 4,826,792 4,831,424 RGD:9068941
G Ext1 exostosin glycosyltransferase 1 JBrowse link NW_004955417 23,798,044 24,067,759 RGD:9068941
G Fgf9 fibroblast growth factor 9 JBrowse link NW_004955497 2,199,424 2,232,088 RGD:9068941
G Fgfr1 fibroblast growth factor receptor 1 JBrowse link NW_004955463 14,013,247 14,064,354 RGD:9068941
G Gli2 GLI family zinc finger 2 JBrowse link NW_004955459 8,892,917 9,124,672 RGD:9068941
G Gpld1 glycosylphosphatidylinositol specific phospholipase D1 JBrowse link NW_004955483 2,501,751 2,552,855 RGD:9068941
G Hes5 hes family bHLH transcription factor 5 JBrowse link NW_004955486 8,700,212 8,701,581 RGD:9068941
G Hmga2 high mobility group AT-hook 2 JBrowse link NW_004955458 12,493,790 12,624,805 RGD:9068941
G Hspg2 heparan sulfate proteoglycan 2 JBrowse link NW_004955452 2,056,428 2,141,937 RGD:9068941
G Ift80 intraflagellar transport 80 JBrowse link NW_004955448 10,808,940 10,819,655 RGD:9068941
G Mapk14 mitogen-activated protein kinase 14 JBrowse link NW_004955437 3,836,331 3,884,083 RGD:9068941
G Matn1 matrilin 1 JBrowse link NW_004955452 9,317,726 9,325,803 RGD:9068941
G Mef2c myocyte enhancer factor 2C JBrowse link NW_004955418 22,537,388 22,701,434 RGD:9068941
G Mef2d myocyte enhancer factor 2D JBrowse link NW_004955545 2,569,399 2,602,580 RGD:9068941
G Nfib nuclear factor I B JBrowse link NW_004955434 17,192,188 17,603,503 RGD:9068941
G Osr1 odd-skipped related transcription factor 1 JBrowse link NW_004955469 1,954,470 1,961,344 RGD:9068941
G Osr2 odd-skipped related transciption factor 2 JBrowse link NW_004955417 14,502,450 14,510,015 RGD:9068941
G Prkca protein kinase C alpha JBrowse link NW_004955478 5,686,639 6,090,356 RGD:9068941
G Pth1r parathyroid hormone 1 receptor JBrowse link NW_004955420 25,274,269 25,291,984 RGD:9068941
G Runx2 RUNX family transcription factor 2 JBrowse link NW_004955437 10,598,145 10,885,858 RGD:9068941
G Runx3 RUNX family transcription factor 3 JBrowse link NW_004955452 4,580,444 4,606,820 RGD:9068941
G Scx scleraxis bHLH transcription factor JBrowse link NW_004955454 2,886,981 2,888,829 RGD:9068941
G Shox2 short stature homeobox 2 JBrowse link NW_004955448 8,937,656 8,947,890 RGD:9068941
G Six2 SIX homeobox 2 JBrowse link NW_004955441 12,029,530 12,033,214 RGD:9068941
G Slc39a14 solute carrier family 39 member 14 JBrowse link NW_004955403 45,828,247 45,867,309 RGD:9068941
G Snx19 sorting nexin 19 JBrowse link NW_004955412 31,747,519 31,791,022 RGD:9068941
G Sox5 SRY-box transcription factor 5 JBrowse link NW_004955413 18,831,931 19,676,371 RGD:9068941
G Sox6 SRY-box transcription factor 6 JBrowse link NW_004955414 30,965,626 31,532,473 RGD:9068941
G Sox9 SRY-box transcription factor 9 JBrowse link NW_004955478 941,684 945,563 RGD:9068941
G Tgfb1 transforming growth factor beta 1 JBrowse link NW_004955555 274,405 288,441 RGD:9068941
G Tgfbi transforming growth factor beta induced JBrowse link NW_004955408 31,093,450 31,124,715 RGD:9068941
G Trps1 transcriptional repressor GATA binding 1 JBrowse link NW_004955417 21,674,545 21,913,137 RGD:9068941
G Wnt10b Wnt family member 10B JBrowse link NW_004955500 7,782,782 7,800,281 RGD:9068941
G Wnt2b Wnt family member 2B JBrowse link NW_004955435 15,948,262 15,962,958 RGD:9068941
G Wnt5b Wnt family member 5B JBrowse link NW_004955454 4,158,648 4,192,709 RGD:9068941
G Wnt7a Wnt family member 7A JBrowse link NW_004955429 12,647,993 12,693,998 RGD:9068941
chondrocyte development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acan aggrecan JBrowse link NW_004955416 16,125,536 16,186,046 RGD:9068941
G Bmpr2 bone morphogenetic protein receptor type 2 JBrowse link NW_004955457 12,235,780 12,315,680 RGD:9068941
G Bpnt2 3'(2'), 5'-bisphosphate nucleotidase 2 JBrowse link NW_004955454 15,899,820 15,918,222 RGD:9068941
G Chst11 carbohydrate sulfotransferase 11 JBrowse link NW_004955405 38,985,046 39,134,130 RGD:9068941
G Chsy1 chondroitin sulfate synthase 1 JBrowse link NW_004955416 28,070,981 28,136,848 RGD:9068941
G Col11a1 collagen type XI alpha 1 chain JBrowse link NW_004955435 7,352,617 7,545,235 RGD:9068941
G Ecm1 extracellular matrix protein 1 JBrowse link NW_004955413 293,295 299,293 RGD:9068941
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 JBrowse link NW_004955424 210,867 279,267 RGD:9068941
G Fgf18 fibroblast growth factor 18 JBrowse link NW_004955408 24,225,459 24,260,057 RGD:9068941
G Mia3 MIA SH3 domain ER export factor 3 JBrowse link NW_004955520 1,853,145 1,890,338 RGD:9068941
G Msx2 msh homeobox 2 JBrowse link NW_004955408 27,323,405 27,329,484 RGD:9068941
G Rarg retinoic acid receptor gamma JBrowse link NW_004955458 480,257 501,172 RGD:9068941
G Runx2 RUNX family transcription factor 2 JBrowse link NW_004955437 10,598,145 10,885,858 RGD:9068941
G Sfrp2 secreted frizzled related protein 2 JBrowse link NW_004955471 8,103,937 8,112,596 RGD:9068941
G Shox2 short stature homeobox 2 JBrowse link NW_004955448 8,937,656 8,947,890 RGD:9068941
G Smpd3 sphingomyelin phosphodiesterase 3 JBrowse link NW_004955484 8,207,686 8,298,164 RGD:9068941
G Sox9 SRY-box transcription factor 9 JBrowse link NW_004955478 941,684 945,563 RGD:9068941
G Sulf1 sulfatase 1 JBrowse link NW_004955444 9,902,334 10,066,929 RGD:9068941
G Sulf2 sulfatase 2 JBrowse link NW_004955445 9,919,472 10,020,491 RGD:9068941
chondrocyte development involved in endochondral bone morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Serpinh1 serpin family H member 1 JBrowse link NW_004955414 16,284,845 16,292,828 RGD:9068941
G Smpd3 sphingomyelin phosphodiesterase 3 JBrowse link NW_004955484 8,207,686 8,298,164 RGD:9068941
chondrocyte differentiation involved in endochondral bone morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Axin2 axin 2 JBrowse link NW_004955478 4,952,551 4,982,223 RGD:9068941
G Ihh Indian hedgehog signaling molecule JBrowse link NW_004955453 14,376,665 14,382,536 RGD:9068941
G Scube2 signal peptide, CUB domain and EGF like domain containing 2 JBrowse link NW_004955414 24,751,134 24,818,338 RGD:9068941
G Sox9 SRY-box transcription factor 9 JBrowse link NW_004955478 941,684 945,563 RGD:9068941
G Trip11 thyroid hormone receptor interactor 11 JBrowse link NW_004955438 14,327,400 14,394,022 RGD:9068941
chondrocyte hypertrophy term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mex3c mex-3 RNA binding family member C JBrowse link NW_004955402 36,049,461 36,065,765 RGD:9068941
G Sox9 SRY-box transcription factor 9 JBrowse link NW_004955478 941,684 945,563 RGD:9068941
growth plate cartilage chondrocyte development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Col27a1 collagen type XXVII alpha 1 chain JBrowse link NW_004955419 13,289,006 13,411,118 RGD:9068941
G Poc1a POC1 centriolar protein A JBrowse link NW_004955532 3,707,680 3,790,565 RGD:9068941
growth plate cartilage chondrocyte differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nppc natriuretic peptide C JBrowse link NW_004955453 3,884,580 3,888,494 RGD:9068941
growth plate cartilage chondrocyte growth term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Rarg retinoic acid receptor gamma JBrowse link NW_004955458 480,257 501,172 RGD:9068941
G Sox9 SRY-box transcription factor 9 JBrowse link NW_004955478 941,684 945,563 RGD:9068941
G Tgfbr2 transforming growth factor beta receptor 2 JBrowse link NW_004955430 21,919,338 21,999,688 RGD:9068941
growth plate cartilage chondrocyte morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Matn1 matrilin 1 JBrowse link NW_004955452 9,317,726 9,325,803 RGD:9068941
negative regulation of chondrocyte development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G LOC102011120 filamin-interacting protein FAM101A JBrowse link NW_004955482 5,034,075 5,044,162 RGD:9068941
G Pthlh parathyroid hormone like hormone JBrowse link NW_004955505 6,834,533 6,846,909 RGD:9068941
G Rflnb refilin B JBrowse link NW_004955481 2,102,576 2,107,947 RGD:9068941
negative regulation of chondrocyte differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adamts12 ADAM metallopeptidase with thrombospondin type 1 motif 12 JBrowse link NW_004955426 19,146,288 19,471,880 RGD:9068941
G Adamts7 ADAM metallopeptidase with thrombospondin type 1 motif 7 JBrowse link NW_004955450 525,313 581,006 RGD:9068941
G Bmp4 bone morphogenetic protein 4 JBrowse link NW_004955409 9,432,835 9,439,680 RGD:9068941
G Ccn4 cellular communication network factor 4 JBrowse link NW_004955461 7,748,399 7,780,359 RGD:9068941
G Chadl chondroadherin like JBrowse link NW_004955413 26,846,714 26,862,082 RGD:9068941
G Ctnnb1 catenin beta 1 JBrowse link NW_004955420 29,030,716 29,047,447 RGD:9068941
G Efemp1 EGF containing fibulin extracellular matrix protein 1 JBrowse link NW_004955424 27,181,717 27,240,067 RGD:9068941
G Gdf5 growth differentiation factor 5 JBrowse link NW_004955422 25,992,081 25,997,122 RGD:9068941
G Gli2 GLI family zinc finger 2 JBrowse link NW_004955459 8,892,917 9,124,672 RGD:9068941
G Grem1 gremlin 1, DAN family BMP antagonist JBrowse link NW_004955416 1,812,725 1,825,528 RGD:9068941
G Ltbp3 latent transforming growth factor beta binding protein 3 JBrowse link NW_004955422 19,714,161 19,730,344 RGD:9068941
G Nkx3-2 NK3 homeobox 2 JBrowse link NW_004955480 10,212,929 10,215,814 RGD:9068941
G Pth parathyroid hormone JBrowse link NW_004955414 28,828,389 28,831,417 RGD:9068941
G Pthlh parathyroid hormone like hormone JBrowse link NW_004955505 6,834,533 6,846,909 RGD:9068941
G Ptpn11 protein tyrosine phosphatase non-receptor type 11 JBrowse link NW_004955482 8,934,734 9,031,230 RGD:9068941
G Rarb retinoic acid receptor beta JBrowse link NW_004955430 17,067,536 17,457,558 RGD:9068941
G Rarg retinoic acid receptor gamma JBrowse link NW_004955458 480,257 501,172 RGD:9068941
G Snai2 snail family transcriptional repressor 2 JBrowse link NW_004955454 8,759,860 8,763,603 RGD:9068941
G Sox9 SRY-box transcription factor 9 JBrowse link NW_004955478 941,684 945,563 RGD:9068941
G Tgfbr1 transforming growth factor beta receptor 1 JBrowse link NW_004955419 26,490,899 26,546,349 RGD:9068941
G Wnt9a Wnt family member 9A JBrowse link NW_004955581 422,028 438,321 RGD:9068941
positive regulation of chondrocyte differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp6 bone morphogenetic protein 6 JBrowse link NW_004955465 6,053,600 6,201,254 RGD:9068941
G Fgf18 fibroblast growth factor 18 JBrowse link NW_004955408 24,225,459 24,260,057 RGD:9068941
G Gdf5 growth differentiation factor 5 JBrowse link NW_004955422 25,992,081 25,997,122 RGD:9068941
G Gdf6 growth differentiation factor 6 JBrowse link NW_004955417 12,152,448 12,169,173 RGD:9068941
G Gli3 GLI family zinc finger 3 JBrowse link NW_004955460 1,528,457 1,805,584 RGD:9068941
G Hoxa11 homeobox A11 JBrowse link NW_004955410 28,875,780 28,879,643 RGD:9068941
G Hoxd11 homeobox D11 JBrowse link NW_004955403 20,541,870 20,556,574 RGD:9068941
G Loxl2 lysyl oxidase like 2 JBrowse link NW_004955403 46,503,226 46,583,807 RGD:9068941
G Mustn1 musculoskeletal, embryonic nuclear protein 1 JBrowse link NW_004955430 2,790,090 2,793,880 RGD:9068941
G Pkdcc protein kinase domain containing, cytoplasmic JBrowse link NW_004955441 9,462,530 9,471,446 RGD:9068941
G Por P450 (cytochrome) oxidoreductase JBrowse link NW_004955456 14,698,589 14,748,520 RGD:9068941
G Rela RELA proto-oncogene, NF-kB subunit JBrowse link NW_004955422 19,602,930 19,612,263 RGD:9068941
G Runx2 RUNX family transcription factor 2 JBrowse link NW_004955437 10,598,145 10,885,858 RGD:9068941
G Smad3 SMAD family member 3 JBrowse link NW_004955450 8,747,651 8,842,003 RGD:9068941
G Sox5 SRY-box transcription factor 5 JBrowse link NW_004955413 18,831,931 19,676,371 RGD:9068941
G Sox6 SRY-box transcription factor 6 JBrowse link NW_004955414 30,965,626 31,532,473 RGD:9068941
G Sox9 SRY-box transcription factor 9 JBrowse link NW_004955478 941,684 945,563 RGD:9068941
G Thrb thyroid hormone receptor beta JBrowse link NW_004955430 15,992,146 16,322,696 RGD:9068941
G Zbtb16 zinc finger and BTB domain containing 16 JBrowse link NW_004955412 15,668,332 15,845,384 RGD:9068941
G Znf219 zinc finger protein 219 JBrowse link NW_004955550 1,854,330 1,861,836 RGD:9068941
positive regulation of chondrocyte hypertrophy term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Smad7 SMAD family member 7 JBrowse link NW_004955402 34,028,184 34,058,949 RGD:9068941
regulation of chondrocyte development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Axin2 axin 2 JBrowse link NW_004955478 4,952,551 4,982,223 RGD:9068941
regulation of chondrocyte differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ccn2 cellular communication network factor 2 JBrowse link NW_004955436 12,523,602 12,526,986 RGD:9068941
G Glg1 golgi glycoprotein 1 JBrowse link NW_004955484 2,871,390 2,987,913 RGD:9068941
G Hoxa11 homeobox A11 JBrowse link NW_004955410 28,875,780 28,879,643 RGD:9068941
G Hoxd11 homeobox D11 JBrowse link NW_004955403 20,541,870 20,556,574 RGD:9068941
G Lnpk lunapark, ER junction formation factor JBrowse link NW_004955403 20,654,961 20,728,173 RGD:9068941
G Maf MAF bZIP transcription factor JBrowse link NW_004955522 2,514,313 2,519,694 RGD:9068941
G Mdk midkine JBrowse link NW_004955422 1,655,351 1,657,026 RGD:9068941
G Shox2 short stature homeobox 2 JBrowse link NW_004955448 8,937,656 8,947,890 RGD:9068941
G Six2 SIX homeobox 2 JBrowse link NW_004955441 12,029,530 12,033,214 RGD:9068941
G Trps1 transcriptional repressor GATA binding 1 JBrowse link NW_004955417 21,674,545 21,913,137 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 11825
    cellular process 11033
      cellular developmental process 3600
        cell differentiation 3536
          chondrocyte differentiation 111
            chondrocyte development + 30
            chondrocyte differentiation involved in endochondral bone morphogenesis + 13
            negative regulation of chondrocyte differentiation + 23
            positive regulation of chondrocyte differentiation + 21
            regulation of chondrocyte differentiation + 51
Path 2
Term Annotations click to browse term
  biological_process 11825
    developmental process 5547
      anatomical structure development 5189
        multicellular organism development 4755
          system development 4497
            animal organ development 3462
              cartilage development 197
                chondrocyte differentiation 111
                  chondrocyte development + 30
                  chondrocyte differentiation involved in endochondral bone morphogenesis + 13
                  negative regulation of chondrocyte differentiation + 23
                  positive regulation of chondrocyte differentiation + 21
                  regulation of chondrocyte differentiation + 51
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.