ONTOLOGY REPORT - ANNOTATIONS


Term:lens development in camera-type eye
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Accession:GO:0002088 term browser browse the term
Definition:The process whose specific outcome is the progression of the lens over time, from its formation to the mature structure. The lens is a transparent structure in the eye through which light is focused onto the retina. An example of this process is found in Mus musculus.
Synonyms:exact_synonym: lens development;   lens development in camera-style eye


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lens development in camera-type eye term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cdk4 cyclin dependent kinase 4 JBrowse link NW_004955458 5,457,927 5,460,718 RGD:9068941
G Cdon cell adhesion associated, oncogene regulated JBrowse link NW_004955412 27,004,391 27,093,968 RGD:9068941
G Cryab crystallin alpha B JBrowse link NW_004955412 13,626,018 13,629,495 RGD:9068941
G Cryba1 crystallin beta A1 JBrowse link NW_004955481 3,952,976 3,986,548 RGD:9068941
G Cryba2 crystallin beta A2 JBrowse link NW_004955453 14,438,658 14,444,469 RGD:9068941
G Cryba4 crystallin beta A4 JBrowse link NW_004955455 1,176,668 1,187,731 RGD:9068941
G Crybb1 crystallin beta B1 JBrowse link NW_004955455 1,165,048 1,180,826 RGD:9068941
G Crybb3 crystallin beta B3 JBrowse link NW_004955455 45,499 50,694 RGD:9068941
G Crybg3 crystallin beta-gamma domain containing 3 JBrowse link NW_004955407 203,315 329,017 RGD:9068941
G Crygn crystallin gamma N JBrowse link NW_004955491 5,780,537 5,788,655 RGD:9068941
G Crygs crystallin gamma S JBrowse link NW_004955420 21,137,964 21,144,206 RGD:9068941
G Ctns cystinosin, lysosomal cystine transporter JBrowse link NW_004955467 13,151,663 13,169,005 RGD:9068941
G Dlg1 discs large MAGUK scaffold protein 1 JBrowse link NW_004955420 13,068,289 13,273,805 RGD:9068941
G Gata3 GATA binding protein 3 JBrowse link NW_004955421 24,448,446 24,477,885 RGD:9068941
G Gja1 gap junction protein alpha 1 JBrowse link NW_004955436 3,612,533 3,618,095 RGD:9068941
G Gja8 gap junction protein alpha 8 JBrowse link NW_004955568 514,905 516,551 RGD:9068941
G Lim2 lens intrinsic membrane protein 2 JBrowse link NW_004955558 1,019,709 1,024,375 RGD:9068941
G Med1 mediator complex subunit 1 JBrowse link NW_004955451 14,204,326 14,237,809 RGD:9068941
G Nhs NHS actin remodeling regulator JBrowse link NW_004955519 596,216 919,352 RGD:9068941
G Pax6 paired box 6 JBrowse link NW_004955476 10,058,979 10,074,668 RGD:9068941
G Pds5b PDS5 cohesin associated factor B JBrowse link NW_004955431 13,083,229 13,268,680 RGD:9068941
G Pitx3 paired like homeodomain 3 JBrowse link NW_004955485 8,130,244 8,140,292 RGD:9068941
G Prox1 prospero homeobox 1 JBrowse link NW_004955406 3,715,140 3,770,019 RGD:9068941
G Six3 SIX homeobox 3 JBrowse link NW_004955441 11,966,389 11,978,545 RGD:9068941
G Six5 SIX homeobox 5 JBrowse link NW_004955574 221,635 225,474 RGD:9068941
G Slitrk6 SLIT and NTRK like family member 6 JBrowse link NW_004955404 22,738,080 22,744,601 RGD:9068941
G Tbc1d32 TBC1 domain family member 32 JBrowse link NW_004955436 3,385,216 3,542,497 RGD:9068941
G Tgfbr1 transforming growth factor beta receptor 1 JBrowse link NW_004955419 26,490,899 26,546,349 RGD:9068941
G Tgfbr2 transforming growth factor beta receptor 2 JBrowse link NW_004955430 21,919,338 21,999,688 RGD:9068941
G Unc45b unc-45 myosin chaperone B JBrowse link NW_004955481 9,833,918 9,860,202 RGD:9068941
G Wnt2 Wnt family member 2 JBrowse link NW_004955432 22,988,208 23,024,530 RGD:9068941
G Wnt2b Wnt family member 2B JBrowse link NW_004955435 15,948,262 15,962,958 RGD:9068941
G Wnt5a Wnt family member 5A JBrowse link NW_004955430 5,304,817 5,325,684 RGD:9068941
lens fiber cell development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bfsp1 beaded filament structural protein 1 JBrowse link NW_004955415 26,507,381 26,535,545 RGD:9068941
G Bfsp2 beaded filament structural protein 2 JBrowse link NW_004955501 5,083,456 5,145,256 RGD:9068941
G Frs2 fibroblast growth factor receptor substrate 2 JBrowse link NW_004955405 9,785,857 9,884,220 RGD:9068941
G Tmod1 tropomodulin 1 JBrowse link NW_004955419 27,841,424 27,915,540 RGD:9068941
G Vim vimentin JBrowse link NW_004955429 10,708,852 10,716,743 RGD:9068941
G Wnt5b Wnt family member 5B JBrowse link NW_004955454 4,158,648 4,192,709 RGD:9068941
G Wnt7a Wnt family member 7A JBrowse link NW_004955429 12,647,993 12,693,998 RGD:9068941
G Wnt7b Wnt family member 7B JBrowse link NW_004955413 30,146,185 30,185,693 RGD:9068941
lens fiber cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fzr1 fizzy and cell division cycle 20 related 1 JBrowse link NW_004955495 5,481,914 5,503,690 RGD:9068941
G Kdm5b lysine demethylase 5B JBrowse link NW_004955406 38,755,220 38,823,094 RGD:9068941
G Maf MAF bZIP transcription factor JBrowse link NW_004955522 2,514,313 2,519,694 RGD:9068941
G Nf2 neurofibromin 2 JBrowse link NW_004955455 3,862,804 3,950,669 RGD:9068941
G Ntrk3 neurotrophic receptor tyrosine kinase 3 JBrowse link NW_004955416 16,652,931 17,018,188 RGD:9068941
G Pitx3 paired like homeodomain 3 JBrowse link NW_004955485 8,130,244 8,140,292 RGD:9068941
G Six3 SIX homeobox 3 JBrowse link NW_004955441 11,966,389 11,978,545 RGD:9068941
G Skil SKI like proto-oncogene JBrowse link NW_004955420 530,531 554,308 RGD:9068941
G Slc7a11 solute carrier family 7 member 11 JBrowse link NW_004955428 5,238,460 5,309,085 RGD:9068941
G Smad3 SMAD family member 3 JBrowse link NW_004955450 8,747,651 8,842,003 RGD:9068941
G Tdrd7 tudor domain containing 7 JBrowse link NW_004955419 27,919,664 27,983,426 RGD:9068941
G Tgfb1 transforming growth factor beta 1 JBrowse link NW_004955555 274,405 288,441 RGD:9068941
lens fiber cell morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abi2 abl interactor 2 JBrowse link NW_004955457 11,451,851 11,562,692 RGD:9068941
G Epha2 EPH receptor A2 JBrowse link NW_004955527 2,120,447 2,151,932 RGD:9068941
G Prox1 prospero homeobox 1 JBrowse link NW_004955406 3,715,140 3,770,019 RGD:9068941
G Prox2 prospero homeobox 2 JBrowse link NW_004955523 697,475 708,675 RGD:9068941
G Tbc1d20 TBC1 domain family member 20 JBrowse link NW_004955597 291,541 313,799 RGD:9068941
lens induction in camera-type eye term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp4 bone morphogenetic protein 4 JBrowse link NW_004955409 9,432,835 9,439,680 RGD:9068941
G Hipk1 homeodomain interacting protein kinase 1 JBrowse link NW_004955435 17,201,866 17,257,371 RGD:9068941
G Hipk2 homeodomain interacting protein kinase 2 JBrowse link NW_004955494 3,365,826 3,554,735 RGD:9068941
G Six3 SIX homeobox 3 JBrowse link NW_004955441 11,966,389 11,978,545 RGD:9068941
lens morphogenesis in camera-type eye term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bcar3 BCAR3 adaptor protein, NSP family member JBrowse link NW_004955423 991,046 1,105,033 RGD:9068941
G Cited2 Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2 JBrowse link NW_004955436 20,370,950 20,372,677 RGD:9068941
G Ctnnb1 catenin beta 1 JBrowse link NW_004955420 29,030,716 29,047,447 RGD:9068941
G Lctl lactase like JBrowse link NW_004955450 9,127,151 9,139,836 RGD:9068941
G Meis1 Meis homeobox 1 JBrowse link NW_004955424 18,060,499 18,190,425 RGD:9068941
G Nectin1 nectin cell adhesion molecule 1 JBrowse link NW_004955412 20,683,007 20,745,069 RGD:9068941
G Nectin3 nectin cell adhesion molecule 3 JBrowse link NW_004955427 11,639,942 11,731,910 RGD:9068941
G Pitx3 paired like homeodomain 3 JBrowse link NW_004955485 8,130,244 8,140,292 RGD:9068941
G Shroom2 shroom family member 2 JBrowse link NW_004955499 8,031,961 8,103,307 RGD:9068941
G Ski SKI proto-oncogene JBrowse link NW_004955486 8,857,693 8,921,821 RGD:9068941
G Sox11 SRY-box 11 JBrowse link NW_004955487 2,678,961 2,680,869 RGD:9068941
G Tdrd7 tudor domain containing 7 JBrowse link NW_004955419 27,919,664 27,983,426 RGD:9068941
positive regulation of lens epithelial cell proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Sox11 SRY-box 11 JBrowse link NW_004955487 2,678,961 2,680,869 RGD:9068941
positive regulation of lens fiber cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Zeb2 zinc finger E-box binding homeobox 2 JBrowse link NW_004955440 10,755,658 10,881,044 RGD:9068941
regulation of lens fiber cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cdkn1b cyclin dependent kinase inhibitor 1B JBrowse link NW_004955413 9,615,542 9,620,542 RGD:9068941
G Cdkn1c cyclin dependent kinase inhibitor 1C JBrowse link NW_004955422 14,576,971 14,578,868 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 14528
    developmental process 5698
      anatomical structure development 5351
        lens development in camera-type eye 71
          lens epithelial cell proliferation + 1
          lens fiber cell differentiation + 28
          lens morphogenesis in camera-type eye + 21
Path 2
Term Annotations click to browse term
  biological_process 14528
    developmental process 5698
      anatomical structure development 5351
        multicellular organism development 4914
          system development 4424
            animal organ development 3244
              sensory organ development 534
                eye development 351
                  camera-type eye development 303
                    lens development in camera-type eye 71
                      lens epithelial cell proliferation + 1
                      lens fiber cell differentiation + 28
                      lens morphogenesis in camera-type eye + 21
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.