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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of receptor internalization
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Accession:GO:0002092 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of receptor internalization.
Synonyms:exact_synonym: up regulation of receptor internalization;   upregulation of receptor internalization
 narrow_synonym: activation of receptor internalization;   stimulation of receptor internalization


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positive regulation of receptor internalization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahi1 Abelson helper integration site 1 ISO
ISS
(MGI:MGI:4840150|PMID:20956301)
GO_REF:0000024
RGD
UniProt
PMID:20956301 GO_REF:0000024, MGI:MGI:4840150 NCBI chr 1:16,478,127...16,601,769
Ensembl chr 1:16,478,127...16,601,769
JBrowse link
G Angpt1 angiopoietin 1 IEA
ISO
GO_REF:0000107
(PMID:19424712)
Ensembl
RGD
PMID:19424712 GO_REF:0000107 NCBI chr 7:81,338,327...81,592,459
Ensembl chr 7:81,342,280...81,592,206
JBrowse link
G Ap2m1 adaptor related protein complex 2 subunit mu 1 IMP RGD PMID:12105201 RGD:13461854 NCBI chr11:84,041,184...84,047,542
Ensembl chr11:84,041,184...84,047,546
JBrowse link
G Arrb1 arrestin, beta 1 ISO
ISS
(PMID:22457824)
GO_REF:0000024
RGD
UniProt
PMID:22457824 GO_REF:0000024 NCBI chr 1:164,502,099...164,573,947
Ensembl chr 1:164,502,389...164,593,139
JBrowse link
G Arrb2 arrestin, beta 2 IMP
ISO
Oprm1
(PMID:22457824)
RGD PMID:22457824, PMID:16120787 RGD:5510008 NCBI chr10:57,040,252...57,048,045
Ensembl chr10:57,040,267...57,048,134
JBrowse link
G Atad1 ATPase family, AAA domain containing 1 ISO
ISS
(MGI:MGI:5050342|PMID:21496646)
GO_REF:0000024
RGD
UniProt
PMID:21496646 GO_REF:0000024, MGI:MGI:5050342 NCBI chr 1:251,234,702...251,386,996
Ensembl chr 1:251,235,508...251,387,002
JBrowse link
G Cd63 Cd63 molecule IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:23632027)
Ensembl
UniProt
RGD
PMID:23632027 GO_REF:0000024, GO_REF:0000107 NCBI chr 7:3,320,250...3,335,583
Ensembl chr 7:3,320,103...3,335,582
JBrowse link
G Dab2 DAB adaptor protein 2 ISO (MGI:MGI:5476876|PMID:23354168) RGD PMID:23354168 MGI:MGI:5476876 NCBI chr 2:55,747,353...55,768,848
Ensembl chr 2:55,747,318...55,768,270
JBrowse link
G Drd2 dopamine receptor D2 IMP RGD PMID:18809670 RGD:2311559 NCBI chr 8:53,678,777...53,743,643
Ensembl chr 8:53,678,777...53,743,642
JBrowse link
G Dtnbp1 dystrobrevin binding protein 1 IMP RGD PMID:17989303 RGD:8553895 NCBI chr17:20,090,136...20,182,332
Ensembl chr17:20,090,246...20,182,206
JBrowse link
G Egf epidermal growth factor ISO (PMID:22732145) RGD PMID:22732145 NCBI chr 2:68,820,616...68,895,537 JBrowse link
G Fmr1 FMRP translational regulator 1 IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:25561520)
Ensembl
UniProt
RGD
PMID:25561520 GO_REF:0000024, GO_REF:0000107 NCBI chr  X:154,684,924...154,722,369
Ensembl chr  X:154,684,935...154,722,314
JBrowse link
G Gh1 growth hormone 1 NOT ISO (PMID:9360546) RGD PMID:9360546 NCBI chr10:94,486,204...94,488,181
Ensembl chr10:94,486,205...94,488,180
JBrowse link
G Grem1 gremlin 1, DAN family BMP antagonist ISO (MGI:MGI:4845816|PMID:20660291) RGD PMID:20660291 MGI:MGI:4845816 NCBI chr 3:105,203,309...105,214,989
Ensembl chr 3:105,203,309...105,214,989
JBrowse link
G Hamp hepcidin antimicrobial peptide ISO (PMID:15514116) RGD PMID:15514116 NCBI chr 1:89,368,021...89,369,960
Ensembl chr 1:89,368,021...89,369,960
JBrowse link
G Insr insulin receptor IEA
ISO
GO_REF:0000107
(PMID:25401701)
Ensembl
RGD
PMID:25401701 GO_REF:0000107 NCBI chr12:1,682,527...1,816,414
Ensembl chr12:1,680,957...1,816,414
JBrowse link
G Magi2 membrane associated guanylate kinase, WW and PDZ domain containing 2 IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:11526121)
Ensembl
UniProt
RGD
PMID:11526121 GO_REF:0000024, GO_REF:0000107 NCBI chr 4:10,995,241...12,472,423
Ensembl chr 4:10,995,234...11,610,518
JBrowse link
G Ntf3 neurotrophin 3 ISO
IEA
(PMID:23027130)
GO_REF:0000107
RGD
Ensembl
PMID:23027130 GO_REF:0000107 NCBI chr 4:158,636,883...158,705,886
Ensembl chr 4:158,636,884...158,705,886
JBrowse link
G Pard3 par-3 family cell polarity regulator ISO (MGI:MGI:5476876|PMID:23354168) RGD PMID:23354168 MGI:MGI:5476876 NCBI chr19:60,017,746...60,580,628
Ensembl chr19:60,017,746...60,580,651
JBrowse link
G Pcsk9 proprotein convertase subtilisin/kexin type 9 ISO (PMID:17328821) RGD PMID:17328821 NCBI chr 5:126,031,368...126,053,726
Ensembl chr 5:126,031,368...126,053,726
JBrowse link
G Pick1 protein interacting with PRKCA 1 IDA
IBA
PMID:18297063
PMID:21873635
UniProt
GO_Central
PMID:18297063, PMID:21873635 RGD:8554748, RGD:13792537 NCBI chr 7:120,465,472...120,484,824
Ensembl chr 7:120,465,130...120,484,840
JBrowse link
G Plcg2 phospholipase C, gamma 2 ISO
IEA
(MGI:MGI:5300392|PMID:22078883)
GO_REF:0000107
RGD
Ensembl
PMID:22078883 GO_REF:0000107, MGI:MGI:5300392 NCBI chr19:50,039,410...50,173,543
Ensembl chr19:50,045,020...50,173,220
JBrowse link
G Ptpn5 protein tyrosine phosphatase, non-receptor type 5 IMP RGD PMID:19625523 RGD:9835004 NCBI chr 1:103,197,918...103,258,309
Ensembl chr 1:103,197,915...103,256,823
JBrowse link
G Scyl2 SCY1 like pseudokinase 2 ISO (PMID:19643732) RGD PMID:19643732 NCBI chr 7:30,291,087...30,344,464
Ensembl chr 7:30,291,087...30,344,445
JBrowse link
G Sele selectin E ISO
IEA
(PMID:9312078)
GO_REF:0000107
RGD
Ensembl
PMID:9312078 GO_REF:0000107 NCBI chr13:82,355,234...82,365,323
Ensembl chr13:82,355,471...82,365,341
JBrowse link
G Sfrp4 secreted frizzled-related protein 4 ISO
IEA
(PMID:16151791)
GO_REF:0000107
RGD
Ensembl
PMID:16151791 GO_REF:0000107 NCBI chr17:47,383,983...47,394,065
Ensembl chr17:47,297,489...47,394,328
JBrowse link
G Syk spleen associated tyrosine kinase IEA
ISO
GO_REF:0000107
(MGI:MGI:5300392|PMID:22078883), (MGI:MGI:5619729|PMID:23962979)
Ensembl
RGD
PMID:22078883, PMID:23962979 GO_REF:0000107, MGI:MGI:5300392, MGI:MGI:5619729 NCBI chr17:12,614,311...12,669,568
Ensembl chr17:12,614,311...12,669,573
JBrowse link
G Synj2bp synaptojanin 2 binding protein ISO (MGI:MGI:3623710|PMID:16648306) RGD PMID:16648306 MGI:MGI:3623710 NCBI chr 6:105,224,166...105,261,549
Ensembl chr 6:105,224,166...105,261,549
JBrowse link
G Tbc1d5 TBC1 domain family, member 5 ISO (PMID:22354992) RGD PMID:22354992 NCBI chr 9:1,144,641...1,747,732
Ensembl chr 9:1,145,700...1,746,397
JBrowse link
G Vegfa vascular endothelial growth factor A ISO (PMID:20660291) RGD PMID:20660291 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
G Wnt3a Wnt family member 3A ISO (PMID:16890161) RGD PMID:16890161 NCBI chr10:45,598,898...45,643,151
Ensembl chr10:45,598,912...45,638,035
JBrowse link
positive regulation of G protein-coupled receptor internalization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apln apelin IDA
ISO
PMID:11359874
(PMID:11359874)
(MGI:MGI:5902690|PMID:11359874)
RGD PMID:11359874, PMID:11359874 MGI:MGI:5902690, RGD:12907555 NCBI chr  X:134,856,719...134,866,210
Ensembl chr  X:134,856,726...134,866,210
JBrowse link
G App amyloid beta precursor protein ISO (PMID:18723082) RGD PMID:18723082 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20017
    metabolic process 12256
      positive regulation of metabolic process 4083
        positive regulation of macromolecule metabolic process 3765
          positive regulation of receptor internalization 33
            positive regulation of G protein-coupled receptor internalization 2
Path 2
Term Annotations click to browse term
  biological_process 20017
    localization 6486
      establishment of localization 4918
        transport 4774
          vesicle-mediated transport 1652
            endocytosis 677
              receptor-mediated endocytosis 246
                receptor internalization 130
                  regulation of receptor internalization 69
                    positive regulation of receptor internalization 33
                      positive regulation of G protein-coupled receptor internalization 2
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.