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Accession:GO:0002096 term browser browse the term
Definition:A punctate, filamentous structure composed of Bcl10 that appears in the cytoplasm of T-cells shortly after T-cell receptor stimulation. Polkadots stands for Punctate Oligomeric Killing and Activating DOmains Transducing Signals.
Comment:Note that polkadots also contains some amount of MALT1. Interaction with MALT1 is required for formation of the polkadots.

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polkadots term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bcl10 BCL10, immune signaling adaptor JBrowse link 2 251,805,392 251,814,957 RGD:1600115
G Malt1 MALT1 paracaspase JBrowse link 18 61,108,712 61,162,446 RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 19809
    protein-containing complex 5770
      polkadots 2
Path 2
Term Annotations click to browse term
  cellular_component 19809
    intracellular 13790
      cytoplasm 10548
        polkadots 2
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.