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ONTOLOGY REPORT - ANNOTATIONS


Term:kinin cascade
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Accession:GO:0002254 term browser browse the term
Definition:A series of reactions that takes place outside the cell that occur as a result of by-products of tissue damage, including collagen, cartilage, and basement membrane. The ultimate product of the kinin cascade include kallidin and bradykinin, agents known to induce smooth muscle contraction, vasoconstriction, and increased vascular permeability.


show annotations for term's descendants       view all columns           Sort by:
 
Factor XII activation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G F12 coagulation factor XII JBrowse link 17 9,736,577 9,744,420 RGD:1624291
RGD:1600115
G Kng2 kininogen 2 JBrowse link 11 81,509,185 81,516,759 RGD:11062094
plasma kallikrein-kinin cascade term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G F12 coagulation factor XII JBrowse link 17 9,736,577 9,744,420 RGD:1624291
G Prcp prolylcarboxypeptidase JBrowse link 1 157,701,089 157,750,177 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19334
    response to stimulus 10393
      protein activation cascade 13
        kinin cascade 3
          negative regulation of kinin cascade + 0
          plasma kallikrein-kinin cascade + 3
          positive regulation of kinin cascade + 0
          regulation of kinin cascade + 0
          tissue kallikrein-kinin cascade + 0
Path 2
Term Annotations click to browse term
  biological_process 19334
    response to stimulus 10393
      response to stress 3955
        defense response 1565
          inflammatory response 690
            acute inflammatory response 125
              kinin cascade 3
                negative regulation of kinin cascade + 0
                plasma kallikrein-kinin cascade + 3
                positive regulation of kinin cascade + 0
                regulation of kinin cascade + 0
                tissue kallikrein-kinin cascade + 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.