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ONTOLOGY REPORT - ANNOTATIONS


Term:lymphocyte homeostasis
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Accession:GO:0002260 term browser browse the term
Definition:The process of regulating the proliferation and elimination of lymphocytes such that the total number of lymphocytes within a whole or part of an organism is stable over time in the absence of an outside stimulus.


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lymphocyte homeostasis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ahr aryl hydrocarbon receptor JBrowse link 6 54,963,990 55,001,806 RGD:1624291
G Bcl2 BCL2, apoptosis regulator JBrowse link 13 26,605,426 26,769,374 RGD:1624291
G Bcl2l11 BCL2 like 11 JBrowse link 3 120,726,906 120,764,192 RGD:1624291
G Foxn1 forkhead box N1 JBrowse link 10 65,621,142 65,634,666 RGD:1624291
G Lat linker for activation of T cells JBrowse link 1 197,765,644 197,770,669 RGD:1624291
G Skil SKI-like proto-oncogene JBrowse link 2 115,862,932 115,891,304 RGD:1624291
G Slc40a1 solute carrier family 40 member 1 JBrowse link 9 52,819,451 52,830,461 RGD:1624291
G Sos1 SOS Ras/Rac guanine nucleotide exchange factor 1 JBrowse link 6 3,105,443 3,182,977 RGD:1624291
G Sos2 SOS Ras/Rho guanine nucleotide exchange factor 2 JBrowse link 6 91,885,292 92,008,059 RGD:1624291
G Spns2 sphingolipid transporter 2 JBrowse link 10 59,010,428 59,049,482 RGD:1624291
G Spta1 spectrin, alpha, erythrocytic 1 JBrowse link 13 92,264,231 92,340,091 RGD:1624291
G Tnfrsf17 TNF receptor superfamily member 17 JBrowse link 10 4,252,097 4,258,335 RGD:1624291
activation-induced cell death of T cells term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akt1 AKT serine/threonine kinase 1 JBrowse link 6 137,218,398 137,239,970 RGD:1624291
G Dnaja3 DnaJ heat shock protein family (Hsp40) member A3 JBrowse link 10 11,059,701 11,085,186 RGD:1624291
G Fas Fas cell surface death receptor JBrowse link 1 252,589,785 252,624,790 RGD:1624291
G Il2ra interleukin 2 receptor subunit alpha JBrowse link 17 70,500,672 70,547,929 RGD:1624291
G Rps6 ribosomal protein S6 JBrowse link 5 105,197,821 105,200,681 RGD:1624291
G Siva1 SIVA1, apoptosis-inducing factor JBrowse link 6 137,209,999 137,214,379 RGD:1624291
B cell homeostasis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ahr aryl hydrocarbon receptor JBrowse link 6 54,963,990 55,001,806 RGD:1624291
G Bak1 BCL2-antagonist/killer 1 JBrowse link 20 5,609,620 5,618,899 RGD:1624291
G Bax BCL2 associated X, apoptosis regulator JBrowse link 1 101,451,801 101,457,207 RGD:1600115
RGD:1624291
G Bcl2 BCL2, apoptosis regulator JBrowse link 13 26,605,426 26,769,374 RGD:1600115
RGD:1624291
G Bcl2l11 BCL2 like 11 JBrowse link 3 120,726,906 120,764,192 RGD:1624291
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:1624291
G Dock10 dedicator of cytokinesis 10 JBrowse link 9
9
86,424,638
86,312,470
86,571,854
86,423,054
RGD:1624291
G Dock11 dedicator of cytokinesis 11 JBrowse link X 122,507,169 122,690,463 RGD:1624291
G Foxp3 forkhead box P3 JBrowse link X 15,753,175 15,768,648 RGD:1624291
G Gapt Grb2-binding adaptor protein, transmembrane JBrowse link 2 41,869,555 41,874,130 RGD:1624291
RGD:13792537
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta JBrowse link 16 74,177,233 74,230,809 RGD:1624291
G Ikbkg inhibitor of nuclear factor kappa B kinase regulatory subunit gamma JBrowse link X 156,254,187 156,280,046 RGD:1624291
G Lyn LYN proto-oncogene, Src family tyrosine kinase JBrowse link 5 16,526,058 16,642,648 RGD:1624291
RGD:1600115
G Mef2c myocyte enhancer factor 2C JBrowse link 2 11,658,534 11,822,788 RGD:1600115
RGD:1624291
G Nckap1l NCK associated protein 1 like JBrowse link 7 145,068,239 145,113,507 RGD:1624291
RGD:1600115
G Pik3cd phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta JBrowse link 5 166,602,053 166,628,028 RGD:1624291
G Pirb paired Ig-like receptor B JBrowse link 1 64,074,097 64,081,568 RGD:1624291
G Pkn1 protein kinase N1 JBrowse link 19 24,803,524 24,832,305 RGD:1624291
G Ppp2r3c protein phosphatase 2, regulatory subunit B'', gamma JBrowse link 6 76,056,585 76,079,755 RGD:1624291
RGD:13792537
G Rc3h1 ring finger and CCCH-type domains 1 JBrowse link 13 78,723,028 78,794,663 RGD:1624291
G Rc3h2 ring finger and CCCH-type domains 2 JBrowse link 3 21,621,976 21,676,789 RGD:1624291
G Sos1 SOS Ras/Rac guanine nucleotide exchange factor 1 JBrowse link 6 3,105,443 3,182,977 RGD:1624291
G Sos2 SOS Ras/Rho guanine nucleotide exchange factor 2 JBrowse link 6 91,885,292 92,008,059 RGD:1624291
G Spns2 sphingolipid transporter 2 JBrowse link 10 59,010,428 59,049,482 RGD:1624291
G Tnfrsf13b TNF receptor superfamily member 13B JBrowse link 10 47,399,834 47,422,907 RGD:1624291
RGD:13792537
G Tnfrsf13c TNF receptor superfamily member 13C JBrowse link 7 123,453,799 123,456,289 RGD:1624291
G Tnfsf13b TNF superfamily member 13b JBrowse link 16 85,275,690 85,306,419 RGD:1624291
B-1 B cell homeostasis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase JBrowse link 3 10,041,820 10,145,076 RGD:1624291
G Hif1a hypoxia inducible factor 1 subunit alpha JBrowse link 6 96,810,868 96,856,303 RGD:1624291
RGD:1600115
G Sh2b2 SH2B adaptor protein 2 JBrowse link 12 23,471,477 23,501,043 RGD:1624291
G Tnfaip3 TNF alpha induced protein 3 JBrowse link 1 14,401,103 14,416,369 RGD:1624291
negative regulation of activation-induced cell death of T cells term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fadd Fas associated via death domain JBrowse link 1 217,746,176 217,748,581 RGD:1624291
RGD:1600115
G Gpam glycerol-3-phosphate acyltransferase, mitochondrial JBrowse link 1 275,843,823 275,906,880 RGD:1624291
RGD:1600115
G Tnfrsf4 TNF receptor superfamily member 4 JBrowse link 5 173,447,784 173,450,474 RGD:1624291
G Tsc22d3 TSC22 domain family, member 3 JBrowse link X 111,884,285 111,944,693 RGD:1624291
negative regulation of mature B cell apoptotic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ada adenosine deaminase JBrowse link 3 160,115,840 160,139,947 RGD:1624291
G Bcl10 BCL10, immune signaling adaptor JBrowse link 2 251,805,392 251,814,957 RGD:1624291
RGD:1600115
G Cd44 CD44 molecule (Indian blood group) JBrowse link 3 92,695,083 92,783,820 RGD:1624291
G Cd74 CD74 molecule JBrowse link 18 56,071,420 56,080,851 RGD:1624291
RGD:1600115
G Mif macrophage migration inhibitory factor JBrowse link 20 13,715,219 13,732,980 RGD:1624291
negative regulation of T cell homeostatic proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd24 CD24 molecule JBrowse link 20 48,335,540 48,340,847 RGD:1624291
positive regulation of activated T cell autonomous cell death term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lgals9 galectin 9 JBrowse link 10 64,737,022 64,760,195 RGD:1624291
positive regulation of activation-induced cell death of T cells term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ceacam1 CEA cell adhesion molecule 1 JBrowse link 1 82,327,955 82,344,345 RGD:1624291
G Tgfb2 transforming growth factor, beta 2 JBrowse link 13 105,039,639 105,142,010 RGD:1624291
positive regulation of T cell homeostatic proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd24 CD24 molecule JBrowse link 20 48,335,540 48,340,847 RGD:1624291
regulation of activation-induced cell death of T cells term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ripk3 receptor-interacting serine-threonine kinase 3 JBrowse link 15 34,470,796 34,479,741 RGD:1624291
RGD:1600115
regulation of T cell homeostatic proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Il2 interleukin 2 JBrowse link 2 123,847,150 123,851,854 RGD:1624291
G Il2ra interleukin 2 receptor subunit alpha JBrowse link 17 70,500,672 70,547,929 RGD:1624291
G Lmo1 LIM domain only 1 JBrowse link 1 173,728,183 173,764,288 RGD:1624291
RGD:1600115
T cell homeostasis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ahr aryl hydrocarbon receptor JBrowse link 6 54,963,990 55,001,806 RGD:1624291
G Bcl2 BCL2, apoptosis regulator JBrowse link 13 26,605,426 26,769,374 RGD:1600115
RGD:1624291
G Bcl2l11 BCL2 like 11 JBrowse link 3 120,726,906 120,764,192 RGD:1624291
G Cacna1f calcium voltage-gated channel subunit alpha1 F JBrowse link X 15,712,709 15,741,135 RGD:1600115
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:1624291
G Ccnb2 cyclin B2 JBrowse link 8 76,847,972 76,861,165 RGD:1624291
G Chst3 carbohydrate sulfotransferase 3 JBrowse link 20 29,731,828 29,768,656 RGD:1624291
G Coro1a coronin 1A JBrowse link 1 198,123,883 198,128,890 RGD:1624291
G Fadd Fas associated via death domain JBrowse link 1 217,746,176 217,748,581 RGD:1624291
RGD:1600115
G Fas Fas cell surface death receptor JBrowse link 1 252,589,785 252,624,790 RGD:1624291
G Foxn1 forkhead box N1 JBrowse link 10 65,621,142 65,634,666 RGD:1624291
G Gimap5 GTPase, IMAP family member 5 JBrowse link 4 78,377,228 78,386,683 RGD:1303374
G Gpr174 G protein-coupled receptor 174 JBrowse link X 78,358,347 78,399,944 RGD:1624291
G Il2ra interleukin 2 receptor subunit alpha JBrowse link 17 70,500,672 70,547,929 RGD:1624291
G Jak3 Janus kinase 3 JBrowse link 16 20,107,471 20,120,678 RGD:1624291
RGD:13792537
RGD:1600115
G Nckap1l NCK associated protein 1 like JBrowse link 7 145,068,239 145,113,507 RGD:1624291
RGD:1600115
G P2rx7 purinergic receptor P2X 7 JBrowse link 12 39,353,613 39,396,042 RGD:1624291
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 JBrowse link 18 62,159,128 62,179,635 RGD:1624291
G Ppp2r3c protein phosphatase 2, regulatory subunit B'', gamma JBrowse link 6 76,056,585 76,079,755 RGD:1624291
RGD:13792537
G Ppp3cb protein phosphatase 3 catalytic subunit beta JBrowse link 15 4,209,702 4,236,895 RGD:1624291
RGD:1600115
G Rag1 recombination activating 1 JBrowse link 3 91,206,394 91,217,491 RGD:1624291
G Rc3h1 ring finger and CCCH-type domains 1 JBrowse link 13 78,723,028 78,794,663 RGD:1624291
G Rc3h2 ring finger and CCCH-type domains 2 JBrowse link 3 21,621,976 21,676,789 RGD:1624291
G Ripk3 receptor-interacting serine-threonine kinase 3 JBrowse link 15 34,470,796 34,479,741 RGD:1624291
RGD:1600115
G Sit1 signaling threshold regulating transmembrane adaptor 1 JBrowse link 5 58,985,912 58,987,538 RGD:1600115
G Slc39a3 solute carrier family 39 member 3 JBrowse link 7 11,545,073 11,551,074 RGD:1624291
G Slc46a2 solute carrier family 46, member 2 JBrowse link 5 77,165,463 77,174,177 RGD:1624291
G Spns2 sphingolipid transporter 2 JBrowse link 10 59,010,428 59,049,482 RGD:1624291
G Stat5a signal transducer and activator of transcription 5A JBrowse link 10 88,764,732 88,789,060 RGD:1624291
G Stat5b signal transducer and activator of transcription 5B JBrowse link 10 88,686,207 88,712,313 RGD:1624291
RGD:1600115
G Tcirg1 T-cell immune regulator 1, ATPase H+ transporting V0 subunit A3 JBrowse link 1 219,126,687 219,139,466 RGD:1624291
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:1624291
G Zc3h8 zinc finger CCCH type containing 8 JBrowse link 3 121,471,836 121,488,528 RGD:1624291
T cell homeostatic proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bax BCL2 associated X, apoptosis regulator JBrowse link 1 101,451,801 101,457,207 RGD:1600115
RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19334
    immune system process 2641
      leukocyte homeostasis 111
        lymphocyte homeostasis 78
          B cell homeostasis + 36
          T cell homeostasis + 47
          mucosal lymphocyte homeostasis 0
Path 2
Term Annotations click to browse term
  biological_process 19334
    biological regulation 13336
      regulation of biological quality 4237
        homeostatic process 2018
          homeostasis of number of cells 319
            leukocyte homeostasis 111
              lymphocyte homeostasis 78
                B cell homeostasis + 36
                T cell homeostasis + 47
                mucosal lymphocyte homeostasis 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.