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ONTOLOGY REPORT - ANNOTATIONS


Term:myeloid leukocyte activation
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Accession:GO:0002274 term browser browse the term
Definition:A change in the morphology or behavior of a myeloid leukocyte resulting from exposure to an activating factor such as a cellular or soluble ligand.
Synonyms:exact_synonym: myeloid leucocyte activation


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myeloid leukocyte activation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Tyrobp transmembrane immune signaling adaptor Tyrobp JBrowse link 1 88,875,370 88,879,305 RGD:1624291
basophil activation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Prg3 proteoglycan 3, pro eosinophil major basic protein 2 JBrowse link 3 72,395,194 72,401,254 RGD:1624291
basophil activation involved in immune response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Enpp3 ectonucleotide pyrophosphatase/phosphodiesterase 3 JBrowse link 1 21,613,148 21,684,483 RGD:1600115
RGD:1624291
G Kars lysyl-tRNA synthetase JBrowse link 19 44,212,205 44,231,209 RGD:12793003
RGD:13792537
RGD:1624291
basophil degranulation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pi4k2a phosphatidylinositol 4-kinase type 2 alpha JBrowse link 1 261,337,594 261,362,509 RGD:2306407
eosinophil degranulation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ccl3 C-C motif chemokine ligand 3 JBrowse link 10 70,869,516 70,871,066 RGD:1624291
RGD:1600115
G Vamp2 vesicle-associated membrane protein 2 JBrowse link 10 55,675,171 55,679,405 RGD:1624291
G Vamp7 vesicle-associated membrane protein 7 JBrowse link 12 18,996,566 19,033,714 RGD:8553828
RGD:1624291
G Vamp8 vesicle-associated membrane protein 8 JBrowse link 4 100,250,301 100,252,756 RGD:1624291
histamine secretion by mast cell term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AABR07053516.1 RGD:1600115
G Adora3 adenosine A3 receptor JBrowse link 2 208,336,909 208,379,217 RGD:1624291
G Btk Bruton tyrosine kinase JBrowse link X 105,360,922 105,390,580 RGD:1600535
G Lyn LYN proto-oncogene, Src family tyrosine kinase JBrowse link 5 16,526,058 16,642,648 RGD:1578516
G Snap23 synaptosome associated protein 23 JBrowse link 3 112,333,972 112,362,960 RGD:1624291
G Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta JBrowse link 7 75,573,553 75,598,295 RGD:1625716
macrophage activation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aif1 allograft inflammatory factor 1 JBrowse link 20 5,161,350 5,167,176 RGD:61535
G Crtc3 CREB regulated transcription coactivator 3 JBrowse link 1 142,398,248 142,500,562 RGD:1624291
G Csf2 colony stimulating factor 2 JBrowse link 10 39,602,089 39,604,070 RGD:5131507
G Edn2 endothelin 2 JBrowse link 5 139,098,472 139,106,396 RGD:1624291
RGD:1600115
G Foxp1 forkhead box P1 JBrowse link 4 131,362,178 131,963,466 RGD:1624291
G Il13 interleukin 13 JBrowse link 10 38,982,909 38,985,466 RGD:1624291
G Il4 interleukin 4 JBrowse link 10 38,963,979 38,969,531 RGD:1624291
G Jmjd6 jumonji domain containing 6, arginine demethylase and lysine hydroxylase JBrowse link 10 105,781,752 105,787,803 RGD:1624291
G Slc11a1 solute carrier family 11 member 1 JBrowse link 9 81,655,590 81,666,697 RGD:1600115
RGD:1624291
G Slc7a2 solute carrier family 7 member 2 JBrowse link 16 54,459,409 54,513,349 RGD:1624291
G Tlr1 toll-like receptor 1 JBrowse link 14 45,062,662 45,065,014 RGD:1600115
G Tlr4 toll-like receptor 4 JBrowse link 5 82,587,424 82,601,056 RGD:1624291
RGD:1600115
G Tmem106a transmembrane protein 106A JBrowse link 10 89,484,269 89,493,288 RGD:1600115
RGD:1624291
macrophage activation involved in immune response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dysf dysferlin JBrowse link 4 115,700,942 115,901,873 RGD:1624291
RGD:13792537
G Havcr2 hepatitis A virus cellular receptor 2 JBrowse link 10 31,561,838 31,590,624 RGD:1624291
G Hmgb1 high mobility group box 1 JBrowse link 12 7,082,529 7,090,246 RGD:1624291
G Ifnb1 interferon beta 1 JBrowse link 5 106,865,192 106,865,746 RGD:12903242
G Ifng interferon gamma JBrowse link 7 61,337,383 61,341,419 RGD:1624291
G Il33 interleukin 33 JBrowse link 1 248,112,611 248,147,030 RGD:1624291
G Lbp lipopolysaccharide binding protein JBrowse link 3 154,786,232 154,812,910 RGD:1624291
RGD:13792537
RGD:1600115
G Prkce protein kinase C, epsilon JBrowse link 6 9,483,400 9,973,396 RGD:1624291
G Sbno2 strawberry notch homolog 2 JBrowse link 7 12,471,805 12,515,700 RGD:1624291
RGD:13792537
G Sucnr1 succinate receptor 1 JBrowse link 2 150,211,897 150,212,848 RGD:1624291
RGD:1600115
G Syk spleen associated tyrosine kinase JBrowse link 17 12,614,311 12,669,568 RGD:1600115
RGD:13792537
RGD:1624291
G Ticam1 toll-like receptor adaptor molecule 1 JBrowse link 9 10,780,185 10,790,280 RGD:1624291
G Trex1 three prime repair exonuclease 1 JBrowse link 8 117,796,127 117,797,427 RGD:1624291
G Tyrobp transmembrane immune signaling adaptor Tyrobp JBrowse link 1 88,875,370 88,879,305 RGD:1624291
mast cell activation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd48 Cd48 molecule JBrowse link 13 90,116,601 90,140,371 RGD:1299282
G Chga chromogranin A JBrowse link 6 126,434,226 126,445,569 RGD:1624291
RGD:1600115
G Fcer1g Fc fragment of IgE receptor Ig JBrowse link 13 89,601,894 89,606,326 RGD:1624291
G Fcgr2a Fc fragment of IgG receptor IIa JBrowse link 13 91,146,878 91,163,691 RGD:1624291
G Fcgr2b Fc fragment of IgG receptor IIb JBrowse link 13 89,329,298 89,343,916 RGD:1624291
G Fyb1 FYN binding protein 1 JBrowse link 2 55,834,904 55,983,805 RGD:1624291
G Lcp2 lymphocyte cytosolic protein 2 JBrowse link 10 18,996,523 19,043,289 RGD:1624291
G Mrgprx2 MAS related GPR family member X2 JBrowse link 1 103,743,746 103,760,945 RGD:1624291
G Ndrg1 N-myc downstream regulated 1 JBrowse link 7 107,734,326 107,775,701 RGD:1624291
RGD:1600115
G Rhoh ras homolog family member H JBrowse link 14 43,961,756 43,992,587 RGD:1624291
G Serpine1 serpin family E member 1 JBrowse link 12 22,641,104 22,651,482 RGD:8547726
G Thy1 Thy-1 cell surface antigen JBrowse link 8 48,382,121 48,387,271 RGD:2303643
mast cell degranulation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cbl Cbl proto-oncogene JBrowse link 8 48,481,256 48,564,775 RGD:11576314
G Chga chromogranin A JBrowse link 6 126,434,226 126,445,569 RGD:1600115
RGD:1624291
G Cplx2 complexin 2 JBrowse link 17 10,756,871 10,828,811 RGD:1600115
G Kit KIT proto-oncogene receptor tyrosine kinase JBrowse link 14 35,072,131 35,149,638 RGD:1624291
G Lat linker for activation of T cells JBrowse link 1 197,765,644 197,770,669 RGD:1600115
G Lat2 linker for activation of T cells family, member 2 JBrowse link 12 25,114,099 25,128,381 RGD:1600115
G Milr1 mast cell immunoglobulin-like receptor 1 JBrowse link 10 94,944,243 94,961,795 RGD:1624291
RGD:1600115
G Mrgprx2 MAS related GPR family member X2 JBrowse link 1 103,743,746 103,760,945 RGD:1624291
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 JBrowse link 5 63,781,801 63,822,890 RGD:1624291
RGD:1600115
G Pla2g3 phospholipase A2, group III JBrowse link 14 83,724,828 83,730,614 RGD:1624291
G Rasgrp1 RAS guanyl releasing protein 1 JBrowse link 3 108,984,029 109,044,420 RGD:1624291
G Tac4 tachykinin precursor 4 JBrowse link 10 83,081,168 83,089,487 RGD:1600115
microglial cell activation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ager advanced glycosylation end product-specific receptor JBrowse link 20 4,363,152 4,366,079 RGD:1600115
RGD:1624291
G App amyloid beta precursor protein JBrowse link 11 24,425,013 24,641,872 RGD:1624291
G C1qa complement C1q A chain JBrowse link 5 155,261,254 155,264,101 RGD:1624291
G C5ar1 complement C5a receptor 1 JBrowse link 1 78,186,777 78,195,132 RGD:1624291
G Casp1 caspase 1 JBrowse link 8 2,605,743 2,614,637 RGD:2315925
G Clu clusterin JBrowse link 15 42,626,612 42,665,858 RGD:1624291
RGD:1600115
G Cx3cl1 C-X3-C motif chemokine ligand 1 JBrowse link 19 10,644,267 10,654,861 RGD:9491804
RGD:4892001
G Cx3cr1 C-X3-C motif chemokine receptor 1 JBrowse link 8 128,740,756 128,754,514 RGD:9491776
G Fpr2 formyl peptide receptor 2 JBrowse link 1 59,800,558 59,809,507 RGD:12910993
G Ifng interferon gamma JBrowse link 7 61,337,383 61,341,419 RGD:14397550
RGD:1624291
G Ifngr1 interferon gamma receptor 1 JBrowse link 1 15,062,380 15,080,815 RGD:14397550
RGD:1624291
G Ifngr2 interferon gamma receptor 2 JBrowse link 11 31,694,339 31,712,611 RGD:14397550
G Il13 interleukin 13 JBrowse link 10 38,982,909 38,985,466 RGD:8549634
G Il4 interleukin 4 JBrowse link 10 38,963,979 38,969,531 RGD:8142387
G Itgam integrin subunit alpha M JBrowse link 1 199,495,312 199,545,738 RGD:1624291
G Jak2 Janus kinase 2 JBrowse link 1 247,398,667 247,457,521 RGD:1624291
G Jun Jun proto-oncogene, AP-1 transcription factor subunit JBrowse link 5 114,011,184 114,014,277 RGD:1624291
G Nampt nicotinamide phosphoribosyltransferase JBrowse link 6 52,122,085 52,156,473 RGD:13781879
G P2ry1 purinergic receptor P2Y1 JBrowse link 2 151,314,818 151,320,312 RGD:13673788
G P2ry2 purinergic receptor P2Y2 JBrowse link 1 166,031,228 166,045,423 RGD:13673788
G Snca synuclein alpha JBrowse link 4 90,782,412 90,883,236 RGD:1624291
G Tlr1 toll-like receptor 1 JBrowse link 14 45,062,662 45,065,014 RGD:1643119
G Tlr2 toll-like receptor 2 JBrowse link 2 182,840,171 182,846,061 RGD:1643119
G Tlr3 toll-like receptor 3 JBrowse link 16 50,016,466 50,031,011 RGD:1643119
G Tlr4 toll-like receptor 4 JBrowse link 5 82,587,424 82,601,056 RGD:1643119
G Tlr6 toll-like receptor 6 JBrowse link 14 45,024,351 45,041,188 RGD:1643119
G Tlr7 toll-like receptor 7 JBrowse link X 28,486,836 28,513,004 RGD:1643119
G Tlr8 toll-like receptor 8 JBrowse link X 28,539,158 28,562,803 RGD:1643119
G Tlr9 toll-like receptor 9 JBrowse link 8 114,916,122 114,920,171 RGD:1643119
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:1624291
G Trem2 triggering receptor expressed on myeloid cells 2 JBrowse link 9 14,611,541 14,618,076 RGD:1624291
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 JBrowse link 10 59,799,123 59,824,208 RGD:2316194
microglial cell activation involved in immune response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cx3cr1 C-X3-C motif chemokine receptor 1 JBrowse link 8 128,740,756 128,754,514 RGD:1624291
G Grn granulin precursor JBrowse link 10 90,377,103 90,383,207 RGD:1600115
RGD:1624291
G Il33 interleukin 33 JBrowse link 1 248,112,611 248,147,030 RGD:1624291
RGD:1600115
G Trem2 triggering receptor expressed on myeloid cells 2 JBrowse link 9 14,611,541 14,618,076 RGD:1624291
G Tyrobp transmembrane immune signaling adaptor Tyrobp JBrowse link 1 88,875,370 88,879,305 RGD:1624291
monocyte activation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adam10 ADAM metallopeptidase domain 10 JBrowse link 8 77,107,355 77,237,483 RGD:1624291
G Adam9 ADAM metallopeptidase domain 9 JBrowse link 16 71,810,377 71,887,926 RGD:1624291
G Foxp1 forkhead box P1 JBrowse link 4 131,362,178 131,963,466 RGD:1624291
G Hyal2 hyaluronidase 2 JBrowse link 8 116,324,062 116,328,978 RGD:1600115
RGD:1624291
G Npy neuropeptide Y JBrowse link 4 79,557,856 79,565,059 RGD:1580787
G Spn sialophorin JBrowse link 1 198,572,999 198,585,664 RGD:2306198
monocyte activation involved in immune response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dysf dysferlin JBrowse link 4 115,700,942 115,901,873 RGD:1624291
RGD:13792537
myeloid dendritic cell activation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd244 CD244 molecule JBrowse link 13 89,959,091 89,995,993 RGD:1624291
G Cd99 CD99 molecule (Xg blood group) JBrowse link 20 56,192,426 56,196,961 RGD:1624291
G Hmgb1 high mobility group box 1 JBrowse link 12 7,082,529 7,090,246 RGD:1624291
G Pycard PYD and CARD domain containing JBrowse link 1 199,438,029 199,439,062 RGD:1624291
G Stard7 StAR-related lipid transfer domain containing 7 JBrowse link 3 119,698,655 119,727,303 RGD:1600115
RGD:1624291
myeloid dendritic cell activation involved in immune response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dock2 dedicator of cytokinesis 2 JBrowse link 10 19,181,512 19,603,171 RGD:1624291
G Pycard PYD and CARD domain containing JBrowse link 1 199,438,029 199,439,062 RGD:1624291
G Slamf1 signaling lymphocytic activation molecule family member 1 JBrowse link 13 90,184,545 90,219,170 RGD:1624291
myeloid dendritic cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Batf basic leucine zipper ATF-like transcription factor JBrowse link 6 109,562,415 109,584,541 RGD:1624291
RGD:1600115
G Batf2 basic leucine zipper ATF-like transcription factor 2 JBrowse link 1 221,538,006 221,546,650 RGD:1624291
G Batf3 basic leucine zipper ATF-like transcription factor 3 JBrowse link 13 109,713,376 109,726,438 RGD:1600115
RGD:1624291
G Camk4 calcium/calmodulin-dependent protein kinase IV JBrowse link 18 25,746,878 25,975,962 RGD:1624291
RGD:1600115
G Cd86 CD86 molecule JBrowse link 11 67,060,305 67,117,990 RGD:4892198
G Csf2 colony stimulating factor 2 JBrowse link 10 39,602,089 39,604,070 RGD:1624291
G Dcstamp dendrocyte expressed seven transmembrane protein JBrowse link 7 78,642,016 78,651,763 RGD:1624291
G Dhrs2 dehydrogenase/reductase 2 JBrowse link 15 33,876,701 33,891,559 RGD:1624291
G Gimap5 GTPase, IMAP family member 5 JBrowse link 4 78,377,228 78,386,683 RGD:2303773
G Il4 interleukin 4 JBrowse link 10 38,963,979 38,969,531 RGD:1624291
G Irf4 interferon regulatory factor 4 JBrowse link 17 34,886,746 34,905,191 RGD:1624291
G Ltbr lymphotoxin beta receptor JBrowse link 4 157,822,838 157,829,291 RGD:1624291
G Notch2 notch receptor 2 JBrowse link 2 200,187,184 200,320,403 RGD:1624291
RGD:1600115
G Pirb paired Ig-like receptor B JBrowse link 1 64,074,097 64,081,568 RGD:1624291
G Psen1 presenilin 1 JBrowse link 6 107,169,514 107,221,000 RGD:1624291
G Rbpj recombination signal binding protein for immunoglobulin kappa J region JBrowse link 14 59,657,738 59,865,427 RGD:1624291
G Relb RELB proto-oncogene, NF-kB subunit JBrowse link 1 80,517,081 80,545,019 RGD:1624291
G Spi1 Spi-1 proto-oncogene JBrowse link 3 79,918,127 79,937,708 RGD:1624291
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:1624291
G Tgfbr2 transforming growth factor, beta receptor 2 JBrowse link 8 124,310,288 124,399,345 RGD:1624291
G Tnfsf9 TNF superfamily member 9 JBrowse link 9 9,909,942 9,912,276 RGD:2317345
G Traf6 TNF receptor associated factor 6 JBrowse link 3 91,252,829 91,271,607 RGD:1624291
G Ubd ubiquitin D JBrowse link 20 1,876,175 1,878,126 RGD:1600115
RGD:1624291
negative regulation of eosinophil activation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd300a Cd300a molecule JBrowse link 10 103,437,978 103,451,170 RGD:1624291
negative regulation of eosinophil degranulation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ccr2 C-C motif chemokine receptor 2 RGD:1624291
RGD:1600115
negative regulation of macrophage activation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adgrf5 adhesion G protein-coupled receptor F5 JBrowse link 9 20,091,121 20,195,706 RGD:1624291
RGD:1600115
G Bpi bactericidal/permeability-increasing protein JBrowse link 3 154,741,627 154,768,584 RGD:1624291
RGD:13792537
G Cd200 Cd200 molecule JBrowse link 11 60,371,617 60,398,450 RGD:1624291
RGD:1600115
G Il4 interleukin 4 JBrowse link 10 38,963,979 38,969,531 RGD:5128562
G Lrfn5 leucine rich repeat and fibronectin type III domain containing 5 JBrowse link 6 83,082,593 83,438,601 RGD:1600115
RGD:1624291
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 JBrowse link 3 80,004,130 80,014,197 RGD:1624291
RGD:1600115
G Tff2 trefoil factor 2 JBrowse link 20 9,872,669 9,876,008 RGD:1624291
G Vsig4 V-set and immunoglobulin domain containing 4 JBrowse link X 65,370,851 65,400,298 RGD:1600115
negative regulation of mast cell activation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd300lf Cd300 molecule-like family member F JBrowse link 10 103,669,781 103,690,584 RGD:1624291
RGD:1600115
G Cd84 CD84 molecule JBrowse link 13 90,241,369 90,283,625 RGD:1624291
G Cnr1 cannabinoid receptor 1 JBrowse link 5 49,307,584 49,333,064 RGD:2316220
G Cnr2 cannabinoid receptor 2 JBrowse link 5 154,242,010 154,268,126 RGD:2316220
G Milr1 mast cell immunoglobulin-like receptor 1 JBrowse link 10 94,944,243 94,961,795 RGD:1624291
RGD:1600115
G Rabgef1 RAB guanine nucleotide exchange factor 1 JBrowse link 12 29,960,132 30,004,727 RGD:1624291
negative regulation of mast cell activation involved in immune response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd300a Cd300a molecule JBrowse link 10 103,437,978 103,451,170 RGD:1624291
G Enpp3 ectonucleotide pyrophosphatase/phosphodiesterase 3 JBrowse link 1 21,613,148 21,684,483 RGD:1600115
RGD:1624291
G Fer FER tyrosine kinase JBrowse link 9 111,557,804 111,868,583 RGD:1600115
RGD:1624291
negative regulation of mast cell degranulation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd300a Cd300a molecule JBrowse link 10 103,437,978 103,451,170 RGD:1624291
G Cd84 CD84 molecule JBrowse link 13 90,241,369 90,283,625 RGD:1624291
G Foxf1 forkhead box F1 JBrowse link 19 53,012,306 53,016,100 RGD:1624291
G Hmox1 heme oxygenase 1 JBrowse link 19 14,508,634 14,515,455 RGD:1601626
G Il13ra2 interleukin 13 receptor subunit alpha 2 JBrowse link X 118,443,955 118,514,716 RGD:1624291
RGD:1600115
G Lgals9 galectin 9 JBrowse link 10 64,737,022 64,760,195 RGD:1624291
G Rabgef1 RAB guanine nucleotide exchange factor 1 JBrowse link 12 29,960,132 30,004,727 RGD:1624291
negative regulation of microglial cell activation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cst7 cystatin F JBrowse link 3 146,363,913 146,373,365 RGD:1624291
G Cx3cl1 C-X3-C motif chemokine ligand 1 JBrowse link 19 10,644,267 10,654,861 RGD:13673772
G Grn granulin precursor JBrowse link 10 90,377,103 90,383,207 RGD:1600115
RGD:1624291
G Ldlr low density lipoprotein receptor JBrowse link 8 22,750,425 22,773,305 RGD:1600115
RGD:1624291
G Nr1d1 nuclear receptor subfamily 1, group D, member 1 JBrowse link 10 86,683,875 86,690,815 RGD:1600115
RGD:1624291
G Pparg peroxisome proliferator-activated receptor gamma JBrowse link 4 147,274,055 147,399,383 RGD:1624291
G Syt11 synaptotagmin 11 JBrowse link 2 188,112,301 188,138,180 RGD:1600115
RGD:1624291
G Tafa3 TAFA chemokine like family member 3 JBrowse link 2 207,249,000 207,258,962 RGD:1624291
RGD:13792537
negative regulation of monocyte activation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd33 CD33 molecule JBrowse link 1 98,388,811 98,403,539 RGD:1624291
negative regulation of myeloid dendritic cell activation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd37 CD37 molecule JBrowse link 1 101,230,470 101,236,061 RGD:1624291
G Havcr2 hepatitis A virus cellular receptor 2 JBrowse link 10 31,561,838 31,590,624 RGD:1624291
G Il10 interleukin 10 JBrowse link 13 47,738,933 47,743,392 RGD:1624291
G Tspan32 tetraspanin 32 JBrowse link 1 216,189,535 216,206,202 RGD:1624291
negative regulation of neutrophil activation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd300a Cd300a molecule JBrowse link 10 103,437,978 103,451,170 RGD:1624291
G Grn granulin precursor JBrowse link 10 90,377,103 90,383,207 RGD:1600115
RGD:1624291
negative regulation of neutrophil degranulation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abr ABR activator of RhoGEF and GTPase JBrowse link 10 64,565,121 64,657,079 RGD:1624291
RGD:1600115
G Bcr BCR activator of RhoGEF and GTPase JBrowse link 20 14,421,250 14,546,406 RGD:1624291
neutrophil activation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ccl5 C-C motif chemokine ligand 5 JBrowse link 10 70,739,764 70,744,303 RGD:1624291
RGD:1600115
G Cxcl6 C-X-C motif chemokine ligand 6 JBrowse link 14 18,860,201 18,920,839 RGD:1624291
RGD:1600115
G Cxcr2 C-X-C motif chemokine receptor 2 JBrowse link 9 81,427,275 81,435,065 RGD:1624291
G F2rl1 F2R like trypsin receptor 1 JBrowse link 2 25,222,324 25,235,275 RGD:1624291
RGD:1600115
G Fcar Fc fragment of IgA receptor JBrowse link 1 73,230,392 73,263,462 RGD:1624291
G Fcgr3a Fc fragment of IgG receptor IIIa JBrowse link 13 89,385,775 89,396,047 RGD:1624291
G Il15 interleukin 15 JBrowse link 19 23,542,606 23,624,366 RGD:1600115
RGD:1624291
G Il18 interleukin 18 JBrowse link 8 55,009,666 55,016,286 RGD:1624291
RGD:1600115
G Il18rap interleukin 18 receptor accessory protein JBrowse link 9 47,225,543 47,255,805 RGD:1624291
G Kmt2e lysine methyltransferase 2E JBrowse link 4 8,187,751 8,255,578 RGD:1624291
G Prg3 proteoglycan 3, pro eosinophil major basic protein 2 JBrowse link 3 72,395,194 72,401,254 RGD:1624291
G Prkcd protein kinase C, delta JBrowse link 16 6,655,131 6,675,746 RGD:1624291
RGD:1600115
neutrophil activation involved in immune response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dnase1 deoxyribonuclease 1 JBrowse link 10 11,757,681 11,760,672 RGD:1624291
RGD:13464261
G Dnase1l3 deoxyribonuclease 1-like 3 JBrowse link 15 18,710,492 18,736,476 RGD:1624291
RGD:13464261
G Fcer1g Fc fragment of IgE receptor Ig JBrowse link 13 89,601,894 89,606,326 RGD:1624291
RGD:13792537
G Syk spleen associated tyrosine kinase JBrowse link 17 12,614,311 12,669,568 RGD:1600115
RGD:13792537
RGD:1624291
G Tyrobp transmembrane immune signaling adaptor Tyrobp JBrowse link 1 88,875,370 88,879,305 RGD:1624291
neutrophil degranulation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Anxa3 annexin A3 JBrowse link 14 14,371,921 14,426,503 RGD:1624291
G Myo1f myosin IF JBrowse link 7 18,440,742 18,491,448 RGD:1624291
G Stx11 syntaxin 11 JBrowse link 1 7,039,160 7,064,870 RGD:1624291
G Stxbp2 syntaxin binding protein 2 JBrowse link 12 2,180,101 2,191,863 RGD:1600115
RGD:1624291
G Stxbp3 syntaxin binding protein 3 JBrowse link 2 211,595,763 211,638,756 RGD:1624291
G Vamp2 vesicle-associated membrane protein 2 JBrowse link 10 55,675,171 55,679,405 RGD:1624291
G Vamp7 vesicle-associated membrane protein 7 JBrowse link 12 18,996,566 19,033,714 RGD:8553828
RGD:1624291
G Vamp8 vesicle-associated membrane protein 8 JBrowse link 4 100,250,301 100,252,756 RGD:1624291
positive regulation of eosinophil degranulation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G F2rl1 F2R like trypsin receptor 1 JBrowse link 2 25,222,324 25,235,275 RGD:1624291
G Stx4 syntaxin 4 JBrowse link 1 199,287,384 199,295,606 RGD:1600115
RGD:1624291
positive regulation of histamine secretion by mast cell term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nppa natriuretic peptide A JBrowse link 5 164,808,407 164,809,716 RGD:13461752
G Snx4 sorting nexin 4 JBrowse link 11 70,693,381 70,753,620 RGD:1624291
G Vamp7 vesicle-associated membrane protein 7 JBrowse link 12 18,996,566 19,033,714 RGD:1624291
G Vamp8 vesicle-associated membrane protein 8 JBrowse link 4 100,250,301 100,252,756 RGD:1600115
RGD:1624291
positive regulation of macrophage activation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd1d1 CD1d1 molecule JBrowse link 2 186,330,298 186,333,805 RGD:1624291
G Cebpa CCAAT/enhancer binding protein alpha JBrowse link 1 91,363,492 91,366,164 RGD:1600115
RGD:1624291
G Hamp hepcidin antimicrobial peptide JBrowse link 1 89,368,021 89,369,960 RGD:1624291
G Havcr2 hepatitis A virus cellular receptor 2 JBrowse link 10 31,561,838 31,590,624 RGD:1624291
G Hspd1 heat shock protein family D (Hsp60) member 1 JBrowse link 9 61,680,529 61,691,202 RGD:1624291
G Il10 interleukin 10 JBrowse link 13 47,738,933 47,743,392 RGD:11049473
G Il13 interleukin 13 JBrowse link 10 38,982,909 38,985,466 RGD:1624291
G Il1rl1 interleukin 1 receptor-like 1 JBrowse link 9 47,133,483 47,184,316 RGD:1624291
RGD:1600115
G Il33 interleukin 33 JBrowse link 1 248,112,611 248,147,030 RGD:1624291
RGD:1600115
G Il4r interleukin 4 receptor JBrowse link 1 196,942,343 196,967,221 RGD:1624291
G Kars lysyl-tRNA synthetase JBrowse link 19 44,212,205 44,231,209 RGD:1624291
RGD:13792537
G Lbp lipopolysaccharide binding protein JBrowse link 3 154,786,232 154,812,910 RGD:1624291
RGD:13792537
RGD:1600115
RGD:9685188
G Lgals9 galectin 9 JBrowse link 10 64,737,022 64,760,195 RGD:1624291
G Pla2g4a phospholipase A2 group IVA JBrowse link 13 67,062,252 67,206,688 RGD:1600115
RGD:1624291
G Thbs1 thrombospondin 1 JBrowse link 3 109,862,120 109,873,466 RGD:1624291
G Tlr4 toll-like receptor 4 JBrowse link 5 82,587,424 82,601,056 RGD:1600115
RGD:1624291
G Tlr6 toll-like receptor 6 JBrowse link 14 45,024,351 45,041,188 RGD:1624291
G Tnip2 TNFAIP3 interacting protein 2 JBrowse link 14 81,487,934 81,505,889 RGD:1624291
G Ulbp1 UL16 binding protein 1 JBrowse link 1 1,181,301 1,200,526 RGD:1624291
G Wnt5a Wnt family member 5A JBrowse link 16 4,469,451 4,490,271 RGD:1624291
RGD:1600115
positive regulation of mast cell activation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AABR07032888.1 RGD:13792537
G Cd226 CD226 molecule JBrowse link 18 86,299,392 86,394,772 RGD:1624291
RGD:13792537
G Cd300lb CD300 molecule-like family member b JBrowse link 10 103,471,082 103,481,071 RGD:1624291
G Cftr CF transmembrane conductance regulator JBrowse link 4 42,693,263 42,860,679 RGD:11567226
G Crlf2 cytokine receptor-like factor 2 JBrowse link 14 1,456,843 1,461,543 RGD:1624291
G Havcr1 hepatitis A virus cellular receptor 1 JBrowse link 10 31,813,819 31,860,934 RGD:1624291
G Nectin2 nectin cell adhesion molecule 2 JBrowse link 1 80,631,449 80,666,617 RGD:1624291
G Tslp thymic stromal lymphopoietin JBrowse link 18 25,613,601 25,618,066 RGD:1624291
positive regulation of mast cell activation by Fc-epsilon receptor signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 JBrowse link 5 63,781,801 63,822,890 RGD:1624291
RGD:1600115
positive regulation of mast cell activation involved in immune response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Sphk2 sphingosine kinase 2 JBrowse link 1 101,692,972 101,700,604 RGD:1624291
positive regulation of mast cell degranulation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adora2b adenosine A2B receptor JBrowse link 10 48,569,563 48,586,366 RGD:1624291
RGD:1600115
G Adora3 adenosine A3 receptor JBrowse link 2 208,336,909 208,379,217 RGD:1624291
G Crhr1 corticotropin releasing hormone receptor 1 JBrowse link 10 92,191,473 92,233,662 RGD:5130941
G Fcer1a Fc fragment of IgE receptor Ia JBrowse link 13 91,727,253 91,737,106 RGD:1624291
G Fcer1g Fc fragment of IgE receptor Ig JBrowse link 13 89,601,894 89,606,326 RGD:1624291
G Fgr FGR proto-oncogene, Src family tyrosine kinase JBrowse link 5 151,172,189 151,199,746 RGD:1624291
RGD:1600115
G Gab2 GRB2-associated binding protein 2 JBrowse link 1 162,082,876 162,283,379 RGD:1624291
RGD:1600115
G Gata1 GATA binding protein 1 JBrowse link X 15,273,937 15,281,759 RGD:9587812
G Gata2 GATA binding protein 2 JBrowse link 4 120,129,028 120,142,490 RGD:9587812
G Il13 interleukin 13 JBrowse link 10 38,982,909 38,985,466 RGD:1624291
G Il4 interleukin 4 JBrowse link 10 38,963,979 38,969,531 RGD:1624291
G Il4r interleukin 4 receptor JBrowse link 1 196,942,343 196,967,221 RGD:1624291
G Ms4a2 membrane spanning 4-domains A2 JBrowse link 1 227,957,363 227,965,312 RGD:1578516
G Nppc natriuretic peptide C JBrowse link 9 93,731,436 93,735,636 RGD:13461752
G Pld2 phospholipase D2 JBrowse link 10 57,161,921 57,181,148 RGD:2299903
G Sphk2 sphingosine kinase 2 JBrowse link 1 101,692,972 101,700,604 RGD:1624291
G Stxbp1 syntaxin binding protein 1 JBrowse link 3 11,823,779 11,885,479 RGD:12904029
G Stxbp2 syntaxin binding protein 2 JBrowse link 12 2,180,101 2,191,863 RGD:12904029
G Syk spleen associated tyrosine kinase JBrowse link 17 12,614,311 12,669,568 RGD:2299903
RGD:13792537
RGD:1600115
RGD:1624291
positive regulation of microglial cell activation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ctsc cathepsin C JBrowse link 1 151,918,514 151,949,979 RGD:1624291
G Lrrk2 leucine-rich repeat kinase 2 JBrowse link 7 132,857,311 133,018,549 RGD:13462052
G Mmp8 matrix metallopeptidase 8 JBrowse link 8 5,768,808 5,777,741 RGD:1600115
RGD:1624291
G Stap1 signal transducing adaptor family member 1 JBrowse link 14 23,575,400 23,604,984 RGD:1624291
G Tafa3 TAFA chemokine like family member 3 JBrowse link 2 207,249,000 207,258,962 RGD:1624291
RGD:13792537
G Trem2 triggering receptor expressed on myeloid cells 2 JBrowse link 9 14,611,541 14,618,076 RGD:1624291
G Ttbk1 tau tubulin kinase 1 JBrowse link 9 16,862,305 16,899,399 RGD:1624291
positive regulation of myeloid dendritic cell activation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Clec4d C-type lectin domain family 4, member D JBrowse link 4 156,253,084 156,264,766 RGD:1600115
RGD:1624291
G Klrk1 killer cell lectin like receptor K1 JBrowse link 4 163,392,652 163,403,735 RGD:9685185
positive regulation of neutrophil activation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:14995443
positive regulation of neutrophil degranulation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd177 CD177 molecule JBrowse link 1 82,964,683 82,987,306 RGD:1624291
G Itgam integrin subunit alpha M JBrowse link 1 199,495,312 199,545,738 RGD:1624291
G Itgb2 integrin subunit beta 2 JBrowse link 20 11,777,773 11,815,647 RGD:1624291
G Ptafr platelet-activating factor receptor JBrowse link 5 150,746,284 150,775,675 RGD:10041060
regulation of histamine secretion by mast cell term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Snx6 sorting nexin 6 JBrowse link 6 75,626,927 75,670,172 RGD:1624291
G Vamp2 vesicle-associated membrane protein 2 JBrowse link 10 55,675,171 55,679,405 RGD:1624291
G Vamp3 vesicle-associated membrane protein 3 JBrowse link 5 168,126,157 168,136,628 RGD:1624291
regulation of macrophage activation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd84 CD84 molecule JBrowse link 13 90,241,369 90,283,625 RGD:1624291
G Gpr137b G protein-coupled receptor 137B JBrowse link 17 90,670,852 90,709,003 RGD:1624291
G Mfhas1 malignant fibrous histiocytoma amplified sequence 1 JBrowse link 16 60,120,457 60,208,550 RGD:1624291
G Muc5b mucin 5B, oligomeric mucus/gel-forming JBrowse link 1 214,778,459 214,811,237 RGD:1624291
G Myo18a myosin XVIIIa JBrowse link 10 64,979,770 65,080,535 RGD:1624291
RGD:1600115
G Pja2 praja ring finger ubiquitin ligase 2 JBrowse link 9 111,998,204 112,048,847 RGD:1624291
G Pla2g10 phospholipase A2, group X JBrowse link 10 1,509,732 1,520,970 RGD:1624291
RGD:1600115
G Pla2g5 phospholipase A2, group V JBrowse link 5 157,247,601 157,268,968 RGD:1624291
G Rora RAR-related orphan receptor A JBrowse link 8 75,515,886 75,616,477 RGD:1624291
G Shpk sedoheptulokinase JBrowse link 10 59,765,328 59,789,676 RGD:1624291
G Slc7a2 solute carrier family 7 member 2 JBrowse link 16 54,459,409 54,513,349 RGD:1624291
G Snca synuclein alpha JBrowse link 4 90,782,412 90,883,236 RGD:1624291
regulation of mast cell activation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lyn LYN proto-oncogene, Src family tyrosine kinase JBrowse link 5 16,526,058 16,642,648 RGD:1624291
RGD:1600115
G Plscr1 phospholipid scramblase 1 JBrowse link 8 99,625,523 99,645,882 RGD:2303650
G Ptpre protein tyrosine phosphatase, receptor type, E JBrowse link 1 207,820,719 207,987,123 RGD:1624291
regulation of mast cell degranulation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fer FER tyrosine kinase JBrowse link 9 111,557,804 111,868,583 RGD:13792537
G Fes FES proto-oncogene, tyrosine kinase JBrowse link 1 142,174,648 142,183,884 RGD:1624291
RGD:13792537
G Lyn LYN proto-oncogene, Src family tyrosine kinase JBrowse link 5 16,526,058 16,642,648 RGD:1624291
RGD:13792537
RGD:1600115
G Pdpk1 3-phosphoinositide dependent protein kinase-1 JBrowse link 10 13,446,373 13,525,248 RGD:1624291
G Rac2 Rac family small GTPase 2 JBrowse link 7 119,769,708 119,797,111 RGD:1624291
G RGD1311164 similar to DNA segment, Chr 6, Wayne State University 163, expressed JBrowse link 4 159,483,089 159,518,387 RGD:10047193
G Stxbp2 syntaxin binding protein 2 JBrowse link 12 2,180,101 2,191,863 RGD:2312429
G Unc13d unc-13 homolog D JBrowse link 10 104,613,907 104,628,664 RGD:1600115
RGD:1624291
regulation of microglial cell activation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atm ATM serine/threonine kinase JBrowse link 8 58,015,938 58,119,973 RGD:12879399
G Sphk1 sphingosine kinase 1 JBrowse link 10 105,498,728 105,504,401 RGD:1600115
RGD:1624291
regulation of myeloid dendritic cell activation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Flt3lg Fms related receptor tyrosine kinase 3 ligand JBrowse link 1 101,126,006 101,131,413 RGD:1624291
regulation of neutrophil degranulation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pram1 PML-RARA regulated adaptor molecule 1 JBrowse link 7 18,507,878 18,516,321 RGD:1624291
G Syk spleen associated tyrosine kinase JBrowse link 17 12,614,311 12,669,568 RGD:1600115
RGD:1624291
serotonin secretion by mast cell term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd300a Cd300a molecule JBrowse link 10 103,437,978 103,451,170 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19439
    immune system process 2631
      leukocyte activation 993
        myeloid leukocyte activation 238
          granulocyte activation + 41
          macrophage activation + 99
          mast cell activation + 79
          monocyte activation + 8
          myeloid cell activation involved in immune response + 95
          myeloid dendritic cell activation + 37
Path 2
Term Annotations click to browse term
  biological_process 19439
    cellular process 18178
      cell activation 1114
        leukocyte activation 993
          myeloid leukocyte activation 238
            granulocyte activation + 41
            macrophage activation + 99
            mast cell activation + 79
            monocyte activation + 8
            myeloid cell activation involved in immune response + 95
            myeloid dendritic cell activation + 37
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.