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ONTOLOGY REPORT - ANNOTATIONS


Term:lymphocyte activation involved in immune response
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Accession:GO:0002285 term browser browse the term
Definition:A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.
Synonyms:related_synonym: lymphocyte activation during immune response


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B cell activation involved in immune response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G GPR183 G protein-coupled receptor 183 JBrowse link 13 99,600,695 99,613,671 RGD:9068941
G IFNB1 interferon beta 1 JBrowse link 9 21,540,849 21,541,695 RGD:9068941
B cell proliferation involved in immune response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase JBrowse link 9 130,482,852 130,652,941 RGD:9068941
G CD180 CD180 molecule JBrowse link 5 48,364,874 48,381,700 RGD:9068941
G CD19 CD19 molecule JBrowse link 16 29,320,734 29,327,860 RGD:9068941
G GAPT GRB2 binding adaptor protein, transmembrane JBrowse link 5 57,144,459 57,145,229 RGD:9068941
G PLCL2 phospholipase C like 2 JBrowse link 3 17,154,506 17,351,287 RGD:9068941
G TLR4 toll like receptor 4 JBrowse link 9 117,180,250 117,193,510 RGD:9068941
CD8-positive, alpha-beta T cell differentiation involved in immune response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G EOMES eomesodermin JBrowse link 3 27,923,970 27,930,687 RGD:9068941
cytotoxic T cell degranulation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G RAB27A RAB27A, member RAS oncogene family JBrowse link 15 52,498,202 52,584,731 RGD:9068941
follicular B cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G LOC100984838 low affinity immunoglobulin gamma Fc region receptor II-b JBrowse link 1 140,882,104 140,890,036 RGD:9068941
G PLCG2 phospholipase C gamma 2 JBrowse link 16 81,812,581 81,984,067 RGD:9068941
germinal center B cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ADA adenosine deaminase JBrowse link 20 42,044,613 42,076,868 RGD:9068941
G CDH17 cadherin 17 JBrowse link 8 92,695,117 92,785,121 RGD:9068941
G ITFG2 integrin alpha FG-GAP repeat containing 2 JBrowse link 12 2,865,297 2,889,752 RGD:9068941
isotype switching term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AICDA activation induced cytidine deaminase JBrowse link 12 8,903,288 8,913,895 RGD:9068941
G ATAD5 ATPase family AAA domain containing 5 JBrowse link 17 25,435,787 25,496,752 RGD:9068941
G BATF basic leucine zipper ATF-like transcription factor JBrowse link 14 74,919,115 74,943,652 RGD:9068941
G CD40LG CD40 ligand JBrowse link X 136,042,849 136,055,158 RGD:9068941
G ERCC1 ERCC excision repair 1, endonuclease non-catalytic subunit JBrowse link 19 50,951,674 50,994,600 RGD:9068941
G EXO1 exonuclease 1 JBrowse link 1 222,389,684 222,431,556 RGD:9068941
G EXOSC3 exosome component 3 JBrowse link 9 38,552,659 38,558,075 RGD:9068941
G EXOSC6 exosome component 6 JBrowse link 7 152,645,545 152,657,307 RGD:9068941
G LIG4 DNA ligase 4 JBrowse link 13 108,474,718 108,485,421 RGD:9068941
G MLH1 mutL homolog 1 JBrowse link 3 37,189,439 37,245,801 RGD:9068941
G MSH2 mutS homolog 2 JBrowse link 2A 48,447,207 48,525,638 RGD:9068941
G MSH6 mutS homolog 6 JBrowse link 2A 48,824,469 48,849,779 RGD:9068941
G NBN nibrin JBrowse link 8 88,575,198 88,626,200 RGD:9068941
G RNF168 ring finger protein 168 JBrowse link 3 203,755,988 203,791,324 RGD:9068941
G RNF8 ring finger protein 8 JBrowse link 6 38,108,414 38,145,949 RGD:9068941
G SWAP70 switching B cell complex subunit SWAP70 JBrowse link 11 9,526,752 9,614,422 RGD:9068941
G UNG uracil DNA glycosylase JBrowse link 12 110,067,882 110,080,891 RGD:9068941
isotype switching to IgA isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CCR6 C-C motif chemokine receptor 6 JBrowse link 6 170,069,689 170,084,779 RGD:9068941
isotype switching to IgG isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G HSPD1 heat shock protein family D (Hsp60) member 1 JBrowse link 2B 202,623,497 202,637,045 RGD:9068941
marginal zone B cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BCL3 BCL3 transcription coactivator JBrowse link 19 50,300,536 50,313,005 RGD:9068941
G CDH17 cadherin 17 JBrowse link 8 92,695,117 92,785,121 RGD:9068941
G DLL1 delta like canonical Notch ligand 1 JBrowse link 6 173,535,941 173,545,362 RGD:9068941
G DOCK10 dedicator of cytokinesis 10 JBrowse link 2B 230,577,925 230,794,767 RGD:9068941
G DOCK11 dedicator of cytokinesis 11 JBrowse link X 117,954,489 118,161,355 RGD:9068941
G LFNG LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase JBrowse link 7 2,876,721 2,884,926 RGD:9068941
G MFNG MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase JBrowse link 22 36,218,403 36,236,402 RGD:9068941
G NOTCH2 notch receptor 2 JBrowse link 1 117,537,162 117,612,840 RGD:9068941
G PTK2B protein tyrosine kinase 2 beta JBrowse link 8 23,783,624 23,932,472 RGD:9068941
mature B cell differentiation involved in immune response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G C17H17orf99 chromosome 17 C17orf99 homolog JBrowse link 17 77,776,151 77,796,139 RGD:9068941
G GPR183 G protein-coupled receptor 183 JBrowse link 13 99,600,695 99,613,671 RGD:9068941
G LOC100984838 low affinity immunoglobulin gamma Fc region receptor II-b JBrowse link 1 140,882,104 140,890,036 RGD:9068941
memory T cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G TSC1 TSC complex subunit 1 JBrowse link 9 132,638,003 132,692,264 RGD:9068941
natural killer cell activation involved in immune response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CD244 CD244 molecule JBrowse link 1 140,109,626 140,142,212 RGD:9068941
G IFNA2 interferon alpha 2 JBrowse link 9 21,862,557 21,863,690 RGD:9068941
G IFNA21 interferon alpha 21 JBrowse link 9 21,629,421 21,630,428 RGD:9068941
G IFNA6 interferon alpha 6 JBrowse link 9 21,828,719 21,829,288 RGD:9068941
G IFNA8 interferon alpha 8 JBrowse link 9 21,887,420 21,888,459 RGD:9068941
G IFNB1 interferon beta 1 JBrowse link 9 21,540,849 21,541,695 RGD:9068941
G IFNE interferon epsilon JBrowse link 9 21,959,043 21,960,511 RGD:9068941
G IFNK interferon kappa JBrowse link 9 27,978,446 27,979,069 RGD:9068941
G IFNW1 interferon omega 1 JBrowse link 9 21,604,387 21,605,643 RGD:9068941
G IL12B interleukin 12B JBrowse link 5 161,323,402 161,339,051 RGD:9068941
natural killer cell degranulation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CORO1A coronin 1A JBrowse link 16 30,549,880 30,555,093 RGD:9068941
G KLRF2 killer cell lectin like receptor F2 JBrowse link 12 10,178,501 10,192,800 RGD:9068941
G RAB27A RAB27A, member RAS oncogene family JBrowse link 15 52,498,202 52,584,731 RGD:9068941
G UNC13D unc-13 homolog D JBrowse link 17 75,327,849 75,345,282 RGD:9068941
G VAMP2 vesicle associated membrane protein 2 JBrowse link 17 48,228,253 48,231,948 RGD:9068941
G VAMP7 vesicle associated membrane protein 7 JBrowse link X 155,257,593 155,320,215 RGD:9068941
negative regulation of cytotoxic T cell degranulation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CEACAM1 CEA cell adhesion molecule 1 JBrowse link 19 47,987,522 48,008,739 RGD:9068941
G LOC100984838 low affinity immunoglobulin gamma Fc region receptor II-b JBrowse link 1 140,882,104 140,890,036 RGD:9068941
negative regulation of isotype switching term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PARP3 poly(ADP-ribose) polymerase family member 3 JBrowse link 3 53,112,494 53,119,053 RGD:9068941
negative regulation of isotype switching to IgA isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G THOC1 THO complex 1 JBrowse link 18 17,692,797 17,742,572 RGD:9068941
negative regulation of isotype switching to IgE isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BCL6 BCL6 transcription repressor JBrowse link 3 193,308,296 193,332,452 RGD:9068941
G FOXP3 forkhead box P3 JBrowse link X 49,402,652 49,417,029 RGD:9068941
G NDFIP1 Nedd4 family interacting protein 1 JBrowse link 5 143,596,345 143,622,913 RGD:9068941
negative regulation of memory T cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G FGL2 fibrinogen like 2 JBrowse link 7 82,926,035 82,932,550 RGD:9068941
G LOC100976419 interferon lambda-1 JBrowse link 19 44,942,186 44,944,519 RGD:9068941
negative regulation of natural killer cell differentiation involved in immune response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PGLYRP1 peptidoglycan recognition protein 1 JBrowse link 19 51,569,275 51,573,764 RGD:9068941
G PGLYRP2 peptidoglycan recognition protein 2 JBrowse link 19 15,986,083 15,997,726 RGD:9068941
G PGLYRP3 peptidoglycan recognition protein 3 JBrowse link 1 132,270,957 132,283,860 RGD:9068941
negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G HAVCR2 hepatitis A virus cellular receptor 2 JBrowse link 5 159,107,938 159,134,973 RGD:9068941
G LGALS3 galectin 3 JBrowse link 14 53,990,023 54,006,412 RGD:9068941
negative regulation of T-helper 1 cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G IL4R interleukin 4 receptor JBrowse link 16 27,686,760 27,737,445 RGD:9068941
G JAK3 Janus kinase 3 JBrowse link 19 18,283,157 18,304,641 RGD:9068941
G TNFSF4 TNF superfamily member 4 JBrowse link 1 152,391,450 152,699,026 RGD:9068941
negative regulation of T-helper 17 cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G FOXP3 forkhead box P3 JBrowse link X 49,402,652 49,417,029 RGD:9068941
G IL2 interleukin 2 JBrowse link 4 125,782,563 125,787,819 RGD:9068941
G IL4 interleukin 4 JBrowse link 5 134,253,039 134,261,581 RGD:9068941
G RC3H1 ring finger and CCCH-type domains 1 JBrowse link 1 153,153,048 153,213,402 RGD:9068941
G RC3H2 ring finger and CCCH-type domains 2 JBrowse link 9 122,308,725 122,365,106 RGD:9068941
G SMAD7 SMAD family member 7 JBrowse link 18 45,659,375 45,689,505 RGD:9068941
G TBX21 T-box transcription factor 21 JBrowse link 17 9,973,343 9,988,131 RGD:9068941
G ZBTB7B zinc finger and BTB domain containing 7B JBrowse link 1 133,959,365 133,975,729 RGD:9068941
G ZC3H12A zinc finger CCCH-type containing 12A JBrowse link 1 38,093,036 38,103,556 RGD:9068941
negative regulation of T-helper 17 cell lineage commitment term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G LOXL3 lysyl oxidase like 3 JBrowse link 2A 76,105,957 76,128,495 RGD:9068941
G TBX21 T-box transcription factor 21 JBrowse link 17 9,973,343 9,988,131 RGD:9068941
negative regulation of T-helper 2 cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ANXA1 annexin A1 JBrowse link 9 71,930,148 71,948,779 RGD:9068941
G BCL6 BCL6 transcription repressor JBrowse link 3 193,308,296 193,332,452 RGD:9068941
G HLX H2.0 like homeobox JBrowse link 1 201,500,470 201,506,222 RGD:9068941
G SOCS5 suppressor of cytokine signaling 5 JBrowse link 2A 47,745,216 47,808,566 RGD:9068941
negative regulation of T-helper cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G RC3H1 ring finger and CCCH-type domains 1 JBrowse link 1 153,153,048 153,213,402 RGD:9068941
plasma cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ITM2A integral membrane protein 2A JBrowse link X 78,585,836 78,593,037 RGD:9068941
G LGALS1 galectin 1 JBrowse link 22 36,426,226 36,430,356 RGD:9068941
G NKX2-3 NK2 homeobox 3 JBrowse link 10 99,640,589 99,643,924 RGD:9068941
positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G IFNG interferon gamma JBrowse link 12 68,448,861 68,453,829 RGD:9068941
positive regulation of interleukin-4-dependent isotype switching to IgE isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G TNFSF4 TNF superfamily member 4 JBrowse link 1 152,391,450 152,699,026 RGD:9068941
positive regulation of isotype switching term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G EXOSC3 exosome component 3 JBrowse link 9 38,552,659 38,558,075 RGD:9068941
G EXOSC6 exosome component 6 JBrowse link 7 152,645,545 152,657,307 RGD:9068941
G HMCES 5-hydroxymethylcytosine binding, ES cell specific JBrowse link 3 133,694,676 133,721,519 RGD:9068941
G KMT5B lysine methyltransferase 5B JBrowse link 11 66,546,398 66,581,553 RGD:9068941
G KMT5C lysine methyltransferase 5C JBrowse link 19 61,073,185 61,079,389 RGD:9068941
G MAD2L2 mitotic arrest deficient 2 like 2 JBrowse link 1 11,654,963 11,671,364 RGD:9068941
G PAXIP1 PAX interacting protein 1 JBrowse link 7 158,274,193 158,329,139 RGD:9068941
G RIF1 replication timing regulatory factor 1 JBrowse link 2B 155,985,960 156,109,726 RGD:9068941
G SHLD1 shieldin complex subunit 1 JBrowse link 20 5,537,989 5,642,107 RGD:9068941
G SHLD2 shieldin complex subunit 2 JBrowse link 14 87,923,049 87,928,101 RGD:9068941
G TFRC transferrin receptor JBrowse link 3 203,333,953 203,365,586 RGD:9068941
G TP53BP1 tumor protein p53 binding protein 1 JBrowse link 15 40,519,012 40,626,845 RGD:9068941
positive regulation of isotype switching to IgA isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G MLH1 mutL homolog 1 JBrowse link 3 37,189,439 37,245,801 RGD:9068941
G MSH2 mutS homolog 2 JBrowse link 2A 48,447,207 48,525,638 RGD:9068941
G NSD2 nuclear receptor binding SET domain protein 2 JBrowse link 4 1,938,777 2,027,425 RGD:9068941
G TGFB1 transforming growth factor beta 1 JBrowse link 19 46,831,659 46,852,973 RGD:9068941
G TNFSF13 TNF superfamily member 13 JBrowse link 17 7,576,518 7,579,834 RGD:9068941
positive regulation of isotype switching to IgE isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CLCF1 cardiotrophin like cytokine factor 1 JBrowse link 11 66,034,536 66,042,114 RGD:9068941
G IL4 interleukin 4 JBrowse link 5 134,253,039 134,261,581 RGD:9068941
G STAT6 signal transducer and activator of transcription 6 JBrowse link 12 32,068,645 32,085,099 RGD:9068941
positive regulation of isotype switching to IgG isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ATAD5 ATPase family AAA domain containing 5 JBrowse link 17 25,435,787 25,496,752 RGD:9068941
G CD28 CD28 molecule JBrowse link 2B 209,076,388 209,111,213 RGD:9068941
G CD40 CD40 molecule JBrowse link 20 43,541,619 43,552,994 RGD:9068941
G IL2 interleukin 2 JBrowse link 4 125,782,563 125,787,819 RGD:9068941
G IL4 interleukin 4 JBrowse link 5 134,253,039 134,261,581 RGD:9068941
G MLH1 mutL homolog 1 JBrowse link 3 37,189,439 37,245,801 RGD:9068941
G MSH2 mutS homolog 2 JBrowse link 2A 48,447,207 48,525,638 RGD:9068941
G PAXIP1 PAX interacting protein 1 JBrowse link 7 158,274,193 158,329,139 RGD:9068941
G PTPRC protein tyrosine phosphatase receptor type C JBrowse link 1 178,555,803 178,674,089 RGD:9068941
G TBX21 T-box transcription factor 21 JBrowse link 17 9,973,343 9,988,131 RGD:9068941
positive regulation of memory T cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CD46 CD46 molecule JBrowse link 1 188,138,616 188,182,046 RGD:9068941
G IL12B interleukin 12B JBrowse link 5 161,323,402 161,339,051 RGD:9068941
G IL12RB1 interleukin 12 receptor subunit beta 1 JBrowse link 19 18,513,585 18,541,383 RGD:9068941
G IL23A interleukin 23 subunit alpha JBrowse link 12 32,828,902 32,830,621 RGD:9068941
G IL23R interleukin 23 receptor JBrowse link 1 68,293,514 68,386,815 RGD:9068941
G TNFSF4 TNF superfamily member 4 JBrowse link 1 152,391,450 152,699,026 RGD:9068941
positive regulation of natural killer cell degranulation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AP1G1 adaptor related protein complex 1 subunit gamma 1 JBrowse link 16 71,568,856 71,648,744 RGD:9068941
G CD160 CD160 molecule JBrowse link 1 113,636,195 113,644,493 RGD:9068941
G LAMP1 lysosomal associated membrane protein 1 JBrowse link 13 113,507,400 113,530,179 RGD:9068941
positive regulation of plasma cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G XBP1 X-box binding protein 1 JBrowse link 22 27,566,423 27,572,627 RGD:9068941
positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CD81 CD81 molecule JBrowse link 11 2,442,322 2,449,308 RGD:9068941
G MHC-DMB HLA class II histocompatibility antigen, DM beta chain JBrowse link 6 33,619,511 33,625,956 RGD:9068941
positive regulation of T-helper 1 cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ANXA1 annexin A1 JBrowse link 9 71,930,148 71,948,779 RGD:9068941
G CCL19 C-C motif chemokine ligand 19 JBrowse link 9 35,334,353 35,336,108 RGD:9068941
G CD80 CD80 molecule JBrowse link 3 123,559,559 123,594,870 RGD:9068941
G HLX H2.0 like homeobox JBrowse link 1 201,500,470 201,506,222 RGD:9068941
G RIPK2 receptor interacting serine/threonine kinase 2 JBrowse link 8 88,397,768 88,431,690 RGD:9068941
G SOCS5 suppressor of cytokine signaling 5 JBrowse link 2A 47,745,216 47,808,566 RGD:9068941
positive regulation of T-helper 17 cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G MALT1 MALT1 paracaspase JBrowse link 18 55,395,462 55,473,574 RGD:9068941
G NFKBID NFKB inhibitor delta JBrowse link 19 41,553,727 41,565,216 RGD:9068941
G NFKBIZ NFKB inhibitor zeta JBrowse link 3 105,616,645 105,628,300 RGD:9068941
G NLRP3 NLR family pyrin domain containing 3 JBrowse link 1 228,505,147 228,537,216 RGD:9068941
positive regulation of T-helper 17 cell lineage commitment term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G IL12B interleukin 12B JBrowse link 5 161,323,402 161,339,051 RGD:9068941
G IL12RB1 interleukin 12 receptor subunit beta 1 JBrowse link 19 18,513,585 18,541,383 RGD:9068941
G IL23A interleukin 23 subunit alpha JBrowse link 12 32,828,902 32,830,621 RGD:9068941
G IL23R interleukin 23 receptor JBrowse link 1 68,293,514 68,386,815 RGD:9068941
positive regulation of T-helper 2 cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CD86 CD86 molecule JBrowse link 3 126,059,008 126,124,339 RGD:9068941
G IL18 interleukin 18 JBrowse link 11 110,867,586 110,888,371 RGD:9068941
G IL4R interleukin 4 receptor JBrowse link 16 27,686,760 27,737,445 RGD:9068941
G NLRP3 NLR family pyrin domain containing 3 JBrowse link 1 228,505,147 228,537,216 RGD:9068941
G PRKCZ protein kinase C zeta JBrowse link 1 1,918,653 2,046,236 RGD:9068941
G RARA retinoic acid receptor alpha JBrowse link 17 17,156,923 17,205,451 RGD:9068941
G TNFSF4 TNF superfamily member 4 JBrowse link 1 152,391,450 152,699,026 RGD:9068941
positive regulation of T-helper cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G MYB MYB proto-oncogene, transcription factor JBrowse link 6 136,974,525 137,086,194 RGD:9068941
regulation of isotype switching term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G APLF aprataxin and PNKP like factor JBrowse link 2A 69,632,459 69,744,611 RGD:9068941
G IL10 interleukin 10 JBrowse link 1 186,648,289 186,653,155 RGD:9068941
G IL4 interleukin 4 JBrowse link 5 134,253,039 134,261,581 RGD:9068941
G SUPT6H SPT6 homolog, histone chaperone and transcription elongation factor JBrowse link 17 28,578,199 28,617,347 RGD:9068941
regulation of isotype switching to IgG isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G FOXP3 forkhead box P3 JBrowse link X 49,402,652 49,417,029 RGD:9068941
G IL27RA interleukin 27 receptor subunit alpha JBrowse link 19 14,323,618 14,343,636 RGD:9068941
G NDFIP1 Nedd4 family interacting protein 1 JBrowse link 5 143,596,345 143,622,913 RGD:9068941
regulation of memory T cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BCL6 BCL6 transcription repressor JBrowse link 3 193,308,296 193,332,452 RGD:9068941
regulation of natural killer cell differentiation involved in immune response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ZNF683 zinc finger protein 683 JBrowse link 1 26,690,359 26,703,755 RGD:9068941
regulation of T-helper 1 cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G IL27 interleukin 27 JBrowse link 16 28,979,717 28,984,655 RGD:9068941
regulation of T-helper cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G IRF4 interferon regulatory factor 4 JBrowse link 6 341,637 360,492 RGD:9068941
T cell activation involved in immune response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CD1C CD1c molecule JBrowse link 1 137,437,235 137,441,075 RGD:9068941
G CD74 CD74 molecule JBrowse link 5 151,830,311 151,841,334 RGD:9068941
G EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4 JBrowse link 15 37,128,000 37,229,216 RGD:9068941
G F2RL1 F2R like trypsin receptor 1 JBrowse link 5 39,008,288 39,024,188 RGD:9068941
G IFNA2 interferon alpha 2 JBrowse link 9 21,862,557 21,863,690 RGD:9068941
G IFNA21 interferon alpha 21 JBrowse link 9 21,629,421 21,630,428 RGD:9068941
G IFNA6 interferon alpha 6 JBrowse link 9 21,828,719 21,829,288 RGD:9068941
G IFNA8 interferon alpha 8 JBrowse link 9 21,887,420 21,888,459 RGD:9068941
G IFNB1 interferon beta 1 JBrowse link 9 21,540,849 21,541,695 RGD:9068941
G IFNE interferon epsilon JBrowse link 9 21,959,043 21,960,511 RGD:9068941
G IFNK interferon kappa JBrowse link 9 27,978,446 27,979,069 RGD:9068941
G IFNW1 interferon omega 1 JBrowse link 9 21,604,387 21,605,643 RGD:9068941
G LCP1 lymphocyte cytosolic protein 1 RGD:9068941
G MDK midkine JBrowse link 11 46,890,151 46,893,318 RGD:9068941
G PSEN1 presenilin 1 JBrowse link 14 72,579,024 72,663,876 RGD:9068941
T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G APBB1IP amyloid beta precursor protein binding family B member 1 interacting protein JBrowse link 10 26,978,997 27,104,802 RGD:9068941
G FGL2 fibrinogen like 2 JBrowse link 7 82,926,035 82,932,550 RGD:9068941
G ICAM1 intercellular adhesion molecule 1 JBrowse link 19 10,484,414 10,500,605 RGD:9068941
G ITGAL integrin subunit alpha L JBrowse link 16 30,843,567 30,894,120 RGD:9068941
T cell differentiation involved in immune response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CLEC4D C-type lectin domain family 4 member D JBrowse link 12 8,814,680 8,823,484 RGD:9068941
G CLEC4E C-type lectin domain family 4 member E JBrowse link 12 8,835,598 8,842,081 RGD:9068941
G FCER1G Fc fragment of IgE receptor Ig JBrowse link 1 140,539,555 140,543,545 RGD:9068941
T cell proliferation involved in immune response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G SLC11A1 solute carrier family 11 member 1 JBrowse link 2B 224,238,284 224,252,941 RGD:9068941
G TNFSF18 TNF superfamily member 18 JBrowse link 1 152,251,683 152,262,668 RGD:9068941
G TP53 tumor protein p53 JBrowse link 17 7,687,132 7,706,120 RGD:9068941
T follicular helper cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G FOXP1 forkhead box P1 JBrowse link 3 72,255,364 72,878,625 RGD:9068941
G GPR183 G protein-coupled receptor 183 JBrowse link 13 99,600,695 99,613,671 RGD:9068941
G RC3H1 ring finger and CCCH-type domains 1 JBrowse link 1 153,153,048 153,213,402 RGD:9068941
G RC3H2 ring finger and CCCH-type domains 2 JBrowse link 9 122,308,725 122,365,106 RGD:9068941
T-helper 1 cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G HMGB1 high mobility group box 1 JBrowse link 13 30,173,875 30,179,527 RGD:9068941
G IL18R1 interleukin 18 receptor 1 JBrowse link 2A 103,459,397 103,488,025 RGD:9068941
G LEF1 lymphoid enhancer binding factor 1 JBrowse link 4 111,125,312 111,245,980 RGD:9068941
G RELB RELB proto-oncogene, NF-kB subunit JBrowse link 19 50,563,164 50,590,627 RGD:9068941
G SEMA4A semaphorin 4A JBrowse link 1 135,321,147 135,350,724 RGD:9068941
G TMEM98 transmembrane protein 98 JBrowse link 17 24,136,588 24,146,912 RGD:9068941
T-helper 1 cell lineage commitment term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G MTOR mechanistic target of rapamycin kinase JBrowse link 1 11,093,765 11,249,841 RGD:9068941
G SPN sialophorin JBrowse link 16 30,034,739 30,037,033 RGD:9068941
G STAT6 signal transducer and activator of transcription 6 JBrowse link 12 32,068,645 32,085,099 RGD:9068941
T-helper 17 cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BATF basic leucine zipper ATF-like transcription factor JBrowse link 14 74,919,115 74,943,652 RGD:9068941
G RORA RAR related orphan receptor A JBrowse link 15 57,763,345 57,901,854 RGD:9068941
G RORC RAR related orphan receptor C JBrowse link 1 130,808,705 130,834,490 RGD:9068941
T-helper 17 cell lineage commitment term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BATF basic leucine zipper ATF-like transcription factor JBrowse link 14 74,919,115 74,943,652 RGD:9068941
G IL6 interleukin 6 JBrowse link 7 23,027,560 23,032,419 RGD:9068941
G IRF4 interferon regulatory factor 4 JBrowse link 6 341,637 360,492 RGD:9068941
G LY9 lymphocyte antigen 9 JBrowse link 1 140,075,646 140,107,790 RGD:9068941
G SLAMF6 SLAM family member 6 JBrowse link 1 139,761,121 139,799,348 RGD:9068941
G STAT3 signal transducer and activator of transcription 3 JBrowse link 17 15,152,358 15,227,084 RGD:9068941
T-helper 2 cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BATF basic leucine zipper ATF-like transcription factor JBrowse link 14 74,919,115 74,943,652 RGD:9068941
G BCL3 BCL3 transcription coactivator JBrowse link 19 50,300,536 50,313,005 RGD:9068941
G GATA3 GATA binding protein 3 JBrowse link 10 8,055,853 8,086,271 RGD:9068941
G IL4 interleukin 4 JBrowse link 5 134,253,039 134,261,581 RGD:9068941
T-helper cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ATP7A ATPase copper transporting alpha JBrowse link X 77,205,579 77,342,762 RGD:9068941
G IL12B interleukin 12B JBrowse link 5 161,323,402 161,339,051 RGD:9068941
G PTGER4 prostaglandin E receptor 4 JBrowse link 5 74,731,470 74,745,121 RGD:9068941
G RORC RAR related orphan receptor C JBrowse link 1 130,808,705 130,834,490 RGD:9068941
T-helper cell lineage commitment term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ZFPM1 zinc finger protein, FOG family member 1 JBrowse link 16 88,822,837 88,907,872 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15758
    immune system process 2763
      leukocyte activation 1166
        lymphocyte activation 645
          lymphocyte activation involved in immune response 172
            B cell activation involved in immune response + 76
            T cell activation involved in immune response + 95
            natural killer cell activation involved in immune response + 23
Path 2
Term Annotations click to browse term
  biological_process 15758
    cellular process 15087
      cell activation 1319
        cell activation involved in immune response 672
          leukocyte activation involved in immune response 668
            lymphocyte activation involved in immune response 172
              B cell activation involved in immune response + 76
              T cell activation involved in immune response + 95
              natural killer cell activation involved in immune response + 23
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.