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ONTOLOGY REPORT - ANNOTATIONS


Term:lymphocyte activation involved in immune response
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Accession:GO:0002285 term browser browse the term
Definition:A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.
Synonyms:related_synonym: lymphocyte activation during immune response


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B cell activation involved in immune response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G GPR183 G protein-coupled receptor 183 JBrowse link 13 99,294,273 99,307,399 RGD:2290271
G IFNB1 interferon beta 1 JBrowse link 9 21,077,104 21,077,942 RGD:2290271
B cell proliferation involved in immune response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase JBrowse link 9 130,713,881 130,887,675 RGD:2290271
G CD180 CD180 molecule JBrowse link 5 67,179,613 67,196,799 RGD:2290271
G CD19 CD19 molecule JBrowse link 16 28,931,735 28,939,347 RGD:2290271
G GAPT GRB2 binding adaptor protein, transmembrane JBrowse link 5 58,491,435 58,497,090 RGD:2290271
G PLCL2 phospholipase C like 2 JBrowse link 3 16,802,691 17,090,606 RGD:2290271
G TLR4 toll like receptor 4 JBrowse link 9 117,704,403 117,724,735 RGD:2290271
CD8-positive, alpha-beta T cell differentiation involved in immune response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G EOMES eomesodermin JBrowse link 3 27,715,949 27,722,715 RGD:2290271
cytotoxic T cell degranulation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G RAB27A RAB27A, member RAS oncogene family JBrowse link 15 55,202,966 55,291,338 RGD:2290271
follicular B cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G FCGR2B Fc fragment of IgG receptor IIb JBrowse link 1 161,647,243 161,678,654 RGD:2290271
G PLCG2 phospholipase C gamma 2 JBrowse link 16 81,779,291 81,962,685 RGD:2290271
germinal center B cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ADA adenosine deaminase JBrowse link 20 44,619,519 44,651,758 RGD:2290271
G CDH17 cadherin 17 JBrowse link 8 94,127,162 94,217,278 RGD:2290271
G ITFG2 integrin alpha FG-GAP repeat containing 2 JBrowse link 12 2,812,644 2,859,907 RGD:2290271
isotype switching term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AICDA activation induced cytidine deaminase JBrowse link 12 8,602,170 8,612,970 RGD:2290271
G ATAD5 ATPase family AAA domain containing 5 JBrowse link 17 30,830,830 30,895,869 RGD:2290271
G BATF basic leucine zipper ATF-like transcription factor JBrowse link 14 75,522,469 75,546,992 RGD:2290271
G CD40LG CD40 ligand JBrowse link X 136,648,158 136,660,390 RGD:2290271
G ERCC1 ERCC excision repair 1, endonuclease non-catalytic subunit JBrowse link 19 45,407,334 45,451,547 RGD:2290271
G EXO1 exonuclease 1 JBrowse link 1 241,847,967 241,889,939 RGD:2290271
G EXOSC3 exosome component 3 JBrowse link 9 37,779,714 37,785,092 RGD:2290271
G EXOSC6 exosome component 6 JBrowse link 16 70,246,778 70,251,940 RGD:2290271
G LIG4 DNA ligase 4 JBrowse link 13 108,207,442 108,218,349 RGD:2290271
G MLH1 mutL homolog 1 JBrowse link 3 36,993,350 37,050,846 RGD:2290271
G MSH2 mutS homolog 2 JBrowse link 2 47,403,067 47,634,501 RGD:2290271
G MSH6 mutS homolog 6 JBrowse link 2 47,783,082 47,806,954 RGD:2290271
G NBN nibrin JBrowse link 8 89,933,331 89,984,724 RGD:2290271
G RNF168 ring finger protein 168 JBrowse link 3 196,468,783 196,503,768 RGD:2290271
G RNF8 ring finger protein 8 JBrowse link 6 37,353,983 37,394,734 RGD:2290271
G SWAP70 switching B cell complex subunit SWAP70 JBrowse link 11 9,664,077 9,752,993 RGD:2290271
G UNG uracil DNA glycosylase JBrowse link 12 109,097,597 109,110,992 RGD:2290271
isotype switching to IgA isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CCR6 C-C motif chemokine receptor 6 JBrowse link 6 167,111,807 167,139,141 RGD:2290271
isotype switching to IgG isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G HSPD1 heat shock protein family D (Hsp60) member 1 JBrowse link 2 197,486,584 197,500,274 RGD:2290271
marginal zone B cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BCL3 BCL3 transcription coactivator JBrowse link 19 44,742,620 44,760,044 RGD:2290271
G CDH17 cadherin 17 JBrowse link 8 94,127,162 94,217,278 RGD:2290271
G DLL1 delta like canonical Notch ligand 1 JBrowse link 6 170,282,200 170,291,078 RGD:2290271
G DOCK10 dedicator of cytokinesis 10 JBrowse link 2 224,765,090 225,042,689 RGD:2290271
G DOCK11 dedicator of cytokinesis 11 JBrowse link X 118,495,664 118,686,160 RGD:2290271
G LFNG LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase JBrowse link 7 2,512,529 2,529,177 RGD:2290271
G MFNG MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase JBrowse link 22 37,469,063 37,486,387 RGD:2290271
G NOTCH2 notch receptor 2 JBrowse link 1 119,911,553 120,069,703 RGD:2290271
G PTK2B protein tyrosine kinase 2 beta JBrowse link 8 27,311,478 27,459,391 RGD:2290271
mature B cell differentiation involved in immune response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G C17orf99 chromosome 17 open reading frame 99 JBrowse link 17 78,146,035 78,166,297 RGD:2290271
G FCGR2B Fc fragment of IgG receptor IIb JBrowse link 1 161,647,243 161,678,654 RGD:2290271
G GPR183 G protein-coupled receptor 183 JBrowse link 13 99,294,273 99,307,399 RGD:2290271
memory T cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G TSC1 TSC complex subunit 1 JBrowse link 9 132,891,349 132,945,269 RGD:2290271
natural killer cell activation involved in immune response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CD244 CD244 molecule JBrowse link 1 160,830,160 160,862,892 RGD:2290271
G IFNA1 interferon alpha 1 JBrowse link 9 21,440,439 21,441,316 RGD:2290271
G IFNA10 interferon alpha 10 JBrowse link 9 21,206,181 21,207,143 RGD:2290271
G IFNA13 interferon alpha 13 JBrowse link 9 21,367,372 21,368,057 RGD:2290271
G IFNA14 interferon alpha 14 JBrowse link 9 21,239,002 21,240,005 RGD:2290271
G IFNA16 interferon alpha 16 JBrowse link 9 21,216,373 21,217,311 RGD:2290271
G IFNA17 interferon alpha 17 JBrowse link 9 21,227,243 21,228,222 RGD:2290271
G IFNA2 interferon alpha 2 JBrowse link 9 21,384,255 21,385,398 RGD:2290271
G IFNA21 interferon alpha 21 JBrowse link 9 21,165,637 21,166,660 RGD:2290271
G IFNA4 interferon alpha 4 JBrowse link 9 21,186,618 21,187,682 RGD:2290271
G IFNA5 interferon alpha 5 JBrowse link 9 21,304,326 21,305,313 RGD:2290271
G IFNA6 interferon alpha 6 JBrowse link 9 21,350,318 21,350,887 RGD:2290271
G IFNA7 interferon alpha 7 JBrowse link 9 21,201,469 21,202,205 RGD:2290271
G IFNA8 interferon alpha 8 JBrowse link 9 21,409,117 21,410,185 RGD:2290271
G IFNB1 interferon beta 1 JBrowse link 9 21,077,104 21,077,942 RGD:2290271
G IFNE interferon epsilon JBrowse link 9 21,480,839 21,482,313 RGD:2290271
G IFNK interferon kappa JBrowse link 9 27,524,314 27,526,498 RGD:2290271
G IFNW1 interferon omega 1 JBrowse link 9 21,140,632 21,141,901 RGD:2290271
G IL12B interleukin 12B JBrowse link 5 159,314,780 159,330,487 RGD:2290271
natural killer cell degranulation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CORO1A coronin 1A JBrowse link 16 30,183,410 30,189,076 RGD:2290271
G KLRF2 killer cell lectin like receptor F2 JBrowse link 12 9,881,489 9,895,833 RGD:2290271
G RAB27A RAB27A, member RAS oncogene family JBrowse link 15 55,202,966 55,291,338 RGD:2290271
G UNC13D unc-13 homolog D JBrowse link 17 75,827,225 75,844,404 RGD:2290271
G VAMP2 vesicle associated membrane protein 2 JBrowse link 17 8,159,147 8,162,948 RGD:2290271
G VAMP7 vesicle associated membrane protein 7 JBrowse link X
Y
155,881,318
57,067,838
155,943,769
57,130,289
RGD:2290271
negative regulation of cytotoxic T cell degranulation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CEACAM1 CEA cell adhesion molecule 1 JBrowse link 19 42,507,306 42,528,482 RGD:2290271
G FCGR2B Fc fragment of IgG receptor IIb JBrowse link 1 161,647,243 161,678,654 RGD:2290271
negative regulation of isotype switching term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PARP3 poly(ADP-ribose) polymerase family member 3 JBrowse link 3 51,942,290 51,948,867 RGD:2290271
negative regulation of isotype switching to IgA isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G THOC1 THO complex 1 JBrowse link 18 214,348 268,047 RGD:2290271
negative regulation of isotype switching to IgE isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BCL6 BCL6 transcription repressor JBrowse link 3 187,721,377 187,745,472 RGD:2290271
G FOXP3 forkhead box P3 JBrowse link X 49,250,436 49,264,932 RGD:2290271
G NDFIP1 Nedd4 family interacting protein 1 JBrowse link 5 142,108,779 142,154,440 RGD:2290271
negative regulation of memory T cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G FGL2 fibrinogen like 2 JBrowse link 7 77,193,369 77,199,819 RGD:2290271
G IFNL1 interferon lambda 1 JBrowse link 19 39,296,407 39,298,673 RGD:2290271
negative regulation of natural killer cell degranulation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G HLA-F major histocompatibility complex, class I, F JBrowse link 6 29,723,340 29,740,355 RGD:2290271
negative regulation of natural killer cell differentiation involved in immune response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PGLYRP1 peptidoglycan recognition protein 1 JBrowse link 19 46,019,153 46,023,053 RGD:2290271
G PGLYRP2 peptidoglycan recognition protein 2 JBrowse link 19 15,468,645 15,479,501 RGD:2290271
G PGLYRP3 peptidoglycan recognition protein 3 JBrowse link 1 153,297,589 153,312,975 RGD:2290271
negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G HAVCR2 hepatitis A virus cellular receptor 2 JBrowse link 5 157,085,832 157,109,044 RGD:2290271
G LGALS3 galectin 3 JBrowse link 14 55,129,252 55,145,430 RGD:2290271
G LILRB1 leukocyte immunoglobulin like receptor B1 JBrowse link 19 54,616,930 54,637,925 RGD:2290271
negative regulation of T-helper 1 cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G IL4R interleukin 4 receptor JBrowse link 16 27,313,668 27,364,778 RGD:2290271
G JAK3 Janus kinase 3 JBrowse link 19 17,824,782 17,848,071 RGD:2290271
G TNFSF4 TNF superfamily member 4 JBrowse link 1 173,183,729 173,462,208 RGD:2290271
negative regulation of T-helper 17 cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G FOXP3 forkhead box P3 JBrowse link X 49,250,436 49,264,932 RGD:2290271
G IL2 interleukin 2 JBrowse link 4 122,449,479 122,456,725 RGD:2290271
G IL4 interleukin 4 JBrowse link 5 132,673,986 132,682,678 RGD:2290271
G RC3H1 ring finger and CCCH-type domains 1 JBrowse link 1 173,931,084 174,022,357 RGD:2290271
G RC3H2 ring finger and CCCH-type domains 2 JBrowse link 9 122,844,556 122,905,359 RGD:2290271
G SMAD7 SMAD family member 7 JBrowse link 18 48,919,853 48,950,711 RGD:2290271
G TBX21 T-box transcription factor 21 JBrowse link 17 47,733,236 47,746,122 RGD:2290271
G ZBTB7B zinc finger and BTB domain containing 7B JBrowse link 1 155,002,628 155,018,523 RGD:2290271
G ZC3H12A zinc finger CCCH-type containing 12A JBrowse link 1 37,474,518 37,484,377 RGD:2290271
negative regulation of T-helper 17 cell lineage commitment term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G LOXL3 lysyl oxidase like 3 JBrowse link 2 74,532,258 74,555,719 RGD:2290271
G TBX21 T-box transcription factor 21 JBrowse link 17 47,733,236 47,746,122 RGD:2290271
negative regulation of T-helper 2 cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ANXA1 annexin A1 JBrowse link 9 73,151,865 73,170,393 RGD:2290271
G BCL6 BCL6 transcription repressor JBrowse link 3 187,721,377 187,745,472 RGD:2290271
G HLX H2.0 like homeobox JBrowse link 1 220,879,443 220,885,059 RGD:2290271
G SOCS5 suppressor of cytokine signaling 5 JBrowse link 2 46,698,960 46,763,129 RGD:2290271
negative regulation of T-helper cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G RC3H1 ring finger and CCCH-type domains 1 JBrowse link 1 173,931,084 174,022,357 RGD:2290271
plasma cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ITM2A integral membrane protein 2A JBrowse link X 79,360,384 79,367,552 RGD:2290271
G LGALS1 galectin 1 JBrowse link 22 37,675,636 37,679,802 RGD:2290271
G NKX2-3 NK2 homeobox 3 JBrowse link 10 99,532,942 99,536,524 RGD:2290271
positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G IFNG interferon gamma JBrowse link 12 68,154,768 68,159,740 RGD:2290271
G LGALS9 galectin 9 JBrowse link 17 27,631,172 27,649,560 RGD:2290271
positive regulation of gamma-delta T cell activation involved in immune response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G LILRB1 leukocyte immunoglobulin like receptor B1 JBrowse link 19 54,616,930 54,637,925 RGD:2290271
positive regulation of interleukin-4-dependent isotype switching to IgE isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G TNFSF4 TNF superfamily member 4 JBrowse link 1 173,183,729 173,462,208 RGD:2290271
positive regulation of isotype switching term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G EXOSC3 exosome component 3 JBrowse link 9 37,779,714 37,785,092 RGD:2290271
G EXOSC6 exosome component 6 JBrowse link 16 70,246,778 70,251,940 RGD:2290271
G HMCES 5-hydroxymethylcytosine binding, ES cell specific JBrowse link 3 129,278,832 129,306,186 RGD:2290271
G KMT5B lysine methyltransferase 5B JBrowse link 11 68,154,863 68,213,899 RGD:2290271
G KMT5C lysine methyltransferase 5C JBrowse link 19 55,339,876 55,348,121 RGD:2290271
G MAD2L2 mitotic arrest deficient 2 like 2 JBrowse link 1 11,674,480 11,691,621 RGD:2290271
G PAXIP1 PAX interacting protein 1 JBrowse link 7 154,943,690 155,003,419 RGD:2290271
G RIF1 replication timing regulatory factor 1 JBrowse link 2 151,409,902 151,534,200 RGD:2290271
G SHLD1 shieldin complex subunit 1 JBrowse link 20 5,750,286 5,864,407 RGD:2290271
G SHLD2 shieldin complex subunit 2 JBrowse link 10 87,094,478 87,191,468 RGD:2290271
G SHLD3 shieldin complex subunit 3 JBrowse link 5 65,625,027 65,630,928 RGD:2290271
G TFRC transferrin receptor JBrowse link 3 196,018,694 196,082,123 RGD:2290271
G TP53BP1 tumor protein p53 binding protein 1 JBrowse link 15 43,403,061 43,510,640 RGD:2290271
positive regulation of isotype switching to IgA isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G MLH1 mutL homolog 1 JBrowse link 3 36,993,350 37,050,846 RGD:2290271
G MSH2 mutS homolog 2 JBrowse link 2 47,403,067 47,634,501 RGD:2290271
G NSD2 nuclear receptor binding SET domain protein 2 JBrowse link 4 1,871,393 1,982,207 RGD:2290271
G TGFB1 transforming growth factor beta 1 JBrowse link 19 41,330,323 41,353,922 RGD:2290271
G TNFSF12-TNFSF13 TNFSF12-TNFSF13 readthrough JBrowse link 17 7,549,058 7,561,601 RGD:2290271
G TNFSF13 TNF superfamily member 13 JBrowse link 17 7,558,292 7,561,608 RGD:2290271
positive regulation of isotype switching to IgE isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CLCF1 cardiotrophin like cytokine factor 1 JBrowse link 11 67,364,168 67,374,177 RGD:2290271
G IL4 interleukin 4 JBrowse link 5 132,673,986 132,682,678 RGD:2290271
G STAT6 signal transducer and activator of transcription 6 JBrowse link 12 57,095,408 57,111,413 RGD:2290271
positive regulation of isotype switching to IgG isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ATAD5 ATPase family AAA domain containing 5 JBrowse link 17 30,830,830 30,895,869 RGD:2290271
G CD28 CD28 molecule JBrowse link 2 203,706,475 203,739,756 RGD:2290271
G CD40 CD40 molecule JBrowse link 20 46,118,242 46,129,858 RGD:2290271
G IL2 interleukin 2 JBrowse link 4 122,449,479 122,456,725 RGD:2290271
G IL4 interleukin 4 JBrowse link 5 132,673,986 132,682,678 RGD:2290271
G MLH1 mutL homolog 1 JBrowse link 3 36,993,350 37,050,846 RGD:2290271
G MSH2 mutS homolog 2 JBrowse link 2 47,403,067 47,634,501 RGD:2290271
G PAXIP1 PAX interacting protein 1 JBrowse link 7 154,943,690 155,003,419 RGD:2290271
G PTPRC protein tyrosine phosphatase receptor type C JBrowse link 1 198,638,968 198,757,476 RGD:2290271
G TBX21 T-box transcription factor 21 JBrowse link 17 47,733,236 47,746,122 RGD:2290271
positive regulation of memory T cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CD46 CD46 molecule JBrowse link 1 207,752,038 207,795,516 RGD:2290271
G IL12B interleukin 12B JBrowse link 5 159,314,780 159,330,487 RGD:2290271
G IL12RB1 interleukin 12 receptor subunit beta 1 JBrowse link 19 18,058,994 18,099,027 RGD:2290271
G IL23A interleukin 23 subunit alpha JBrowse link 12 56,334,159 56,340,410 RGD:2290271
G IL23R interleukin 23 receptor JBrowse link 1 67,138,639 67,259,979 RGD:2290271
G TNFSF4 TNF superfamily member 4 JBrowse link 1 173,183,729 173,462,208 RGD:2290271
positive regulation of natural killer cell degranulation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AP1G1 adaptor related protein complex 1 subunit gamma 1 JBrowse link 16 71,729,000 71,808,834 RGD:2290271
G CD160 CD160 molecule JBrowse link 1 145,719,312 145,739,288 RGD:2290271
G HLA-F major histocompatibility complex, class I, F JBrowse link 6 29,723,340 29,740,355 RGD:2290271
G LAMP1 lysosomal associated membrane protein 1 JBrowse link 13 113,297,239 113,323,672 RGD:2290271
positive regulation of plasma cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G XBP1 X-box binding protein 1 JBrowse link 22 28,794,560 28,800,572 RGD:2290271
positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CD81 CD81 molecule JBrowse link 11 2,376,177 2,397,419 RGD:2290271
G HLA-DMB major histocompatibility complex, class II, DM beta JBrowse link 6 32,934,636 32,941,028 RGD:2290271
G LGALS9 galectin 9 JBrowse link 17 27,631,172 27,649,560 RGD:2290271
positive regulation of T-helper 1 cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ANXA1 annexin A1 JBrowse link 9 73,151,865 73,170,393 RGD:2290271
G CCL19 C-C motif chemokine ligand 19 JBrowse link 9 34,689,570 34,691,276 RGD:2290271
G CD80 CD80 molecule JBrowse link 3 119,524,293 119,559,614 RGD:2290271
G HLX H2.0 like homeobox JBrowse link 1 220,879,443 220,885,059 RGD:2290271
G RIPK2 receptor interacting serine/threonine kinase 2 JBrowse link 8 89,757,816 89,791,064 RGD:2290271
G SOCS5 suppressor of cytokine signaling 5 JBrowse link 2 46,698,960 46,763,129 RGD:2290271
positive regulation of T-helper 17 cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G MALT1 MALT1 paracaspase JBrowse link 18 58,671,420 58,754,477 RGD:2290271
G NFKBID NFKB inhibitor delta JBrowse link 19 35,887,630 35,902,303 RGD:2290271
G NFKBIZ NFKB inhibitor zeta JBrowse link 3 101,827,990 101,861,022 RGD:2290271
G NLRP3 NLR family pyrin domain containing 3 JBrowse link 1 247,416,163 247,448,823 RGD:2290271
positive regulation of T-helper 17 cell lineage commitment term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G IL12B interleukin 12B JBrowse link 5 159,314,780 159,330,487 RGD:2290271
G IL12RB1 interleukin 12 receptor subunit beta 1 JBrowse link 19 18,058,994 18,099,027 RGD:2290271
G IL23A interleukin 23 subunit alpha JBrowse link 12 56,334,159 56,340,410 RGD:2290271
G IL23R interleukin 23 receptor JBrowse link 1 67,138,639 67,259,979 RGD:2290271
positive regulation of T-helper 2 cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CD86 CD86 molecule JBrowse link 3 122,055,362 122,121,143 RGD:2290271
G IL18 interleukin 18 JBrowse link 11 112,143,251 112,164,104 RGD:2290271
G IL4R interleukin 4 receptor JBrowse link 16 27,313,668 27,364,778 RGD:2290271
G NLRP3 NLR family pyrin domain containing 3 JBrowse link 1 247,416,163 247,448,823 RGD:2290271
G PRKCZ protein kinase C zeta JBrowse link 1 2,050,411 2,185,399 RGD:2290271
G RARA retinoic acid receptor alpha JBrowse link 17 40,309,180 40,357,643 RGD:2290271
G TNFSF4 TNF superfamily member 4 JBrowse link 1 173,183,729 173,462,208 RGD:2290271
positive regulation of T-helper cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G MYB MYB proto-oncogene, transcription factor JBrowse link 6 135,181,308 135,219,172 RGD:2290271
regulation of isotype switching term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G APLF aprataxin and PNKP like factor JBrowse link 2 68,467,585 68,580,162 RGD:2290271
G IL10 interleukin 10 JBrowse link 1 206,767,602 206,772,494 RGD:2290271
G IL4 interleukin 4 JBrowse link 5 132,673,986 132,682,678 RGD:2290271
G SUPT6H SPT6 homolog, histone chaperone and transcription elongation factor JBrowse link 17 28,662,183 28,702,679 RGD:2290271
regulation of isotype switching to IgG isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G FOXP3 forkhead box P3 JBrowse link X 49,250,436 49,264,932 RGD:2290271
G IL27RA interleukin 27 receptor subunit alpha JBrowse link 19 14,031,762 14,053,218 RGD:2290271
G NDFIP1 Nedd4 family interacting protein 1 JBrowse link 5 142,108,779 142,154,440 RGD:2290271
regulation of memory T cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BCL6 BCL6 transcription repressor JBrowse link 3 187,721,377 187,745,472 RGD:2290271
regulation of natural killer cell differentiation involved in immune response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ZNF683 zinc finger protein 683 JBrowse link 1 26,361,632 26,374,536 RGD:2290271
regulation of T-helper 1 cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G IL27 interleukin 27 JBrowse link 16 28,499,362 28,526,730 RGD:2290271
regulation of T-helper cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G IRF4 interferon regulatory factor 4 JBrowse link 6 391,752 411,443 RGD:2290271
T cell activation involved in immune response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CD1C CD1c molecule JBrowse link 1 158,289,887 158,294,774 RGD:2290271
G CD74 CD74 molecule JBrowse link 5 150,400,041 150,412,936 RGD:2290271
G EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4 JBrowse link 15 39,934,115 40,035,591 RGD:2290271
G F2RL1 F2R like trypsin receptor 1 JBrowse link 5 76,819,030 76,835,315 RGD:2290271
G IFNA1 interferon alpha 1 JBrowse link 9 21,440,439 21,441,316 RGD:2290271
G IFNA10 interferon alpha 10 JBrowse link 9 21,206,181 21,207,143 RGD:2290271
G IFNA13 interferon alpha 13 JBrowse link 9 21,367,372 21,368,057 RGD:2290271
G IFNA14 interferon alpha 14 JBrowse link 9 21,239,002 21,240,005 RGD:2290271
G IFNA16 interferon alpha 16 JBrowse link 9 21,216,373 21,217,311 RGD:2290271
G IFNA17 interferon alpha 17 JBrowse link 9 21,227,243 21,228,222 RGD:2290271
G IFNA2 interferon alpha 2 JBrowse link 9 21,384,255 21,385,398 RGD:2290271
G IFNA21 interferon alpha 21 JBrowse link 9 21,165,637 21,166,660 RGD:2290271
G IFNA4 interferon alpha 4 JBrowse link 9 21,186,618 21,187,682 RGD:2290271
G IFNA5 interferon alpha 5 JBrowse link 9 21,304,326 21,305,313 RGD:2290271
G IFNA6 interferon alpha 6 JBrowse link 9 21,350,318 21,350,887 RGD:2290271
G IFNA7 interferon alpha 7 JBrowse link 9 21,201,469 21,202,205 RGD:2290271
G IFNA8 interferon alpha 8 JBrowse link 9 21,409,117 21,410,185 RGD:2290271
G IFNB1 interferon beta 1 JBrowse link 9 21,077,104 21,077,942 RGD:2290271
G IFNE interferon epsilon JBrowse link 9 21,480,839 21,482,313 RGD:2290271
G IFNK interferon kappa JBrowse link 9 27,524,314 27,526,498 RGD:2290271
G IFNW1 interferon omega 1 JBrowse link 9 21,140,632 21,141,901 RGD:2290271
G LCP1 lymphocyte cytosolic protein 1 JBrowse link 13 46,125,923 46,182,177 RGD:2290271
G MDK midkine JBrowse link 11 46,380,784 46,383,837 RGD:2290271
G PSEN1 presenilin 1 JBrowse link 14 73,136,436 73,223,691 RGD:2290271
T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G APBB1IP amyloid beta precursor protein binding family B member 1 interacting protein JBrowse link 10 26,438,324 26,567,879 RGD:2290271
G FGL2 fibrinogen like 2 JBrowse link 7 77,193,369 77,199,819 RGD:2290271
G ICAM1 intercellular adhesion molecule 1 JBrowse link 19 10,271,120 10,286,615 RGD:2290271
G ITGAL integrin subunit alpha L JBrowse link 16 30,472,683 30,523,185 RGD:2290271
T cell differentiation involved in immune response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CLEC4D C-type lectin domain family 4 member D JBrowse link 12 8,513,492 8,522,366 RGD:2290271
G CLEC4E C-type lectin domain family 4 member E JBrowse link 12 8,533,305 8,541,327 RGD:2290271
G FCER1G Fc fragment of IgE receptor Ig JBrowse link 1 161,215,295 161,219,245 RGD:2290271
T cell proliferation involved in immune response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G LILRB1 leukocyte immunoglobulin like receptor B1 JBrowse link 19 54,616,930 54,637,925 RGD:2290271
G SLC11A1 solute carrier family 11 member 1 JBrowse link 2 218,381,766 218,396,894 RGD:2290271
G TNFSF18 TNF superfamily member 18 JBrowse link 1 173,041,220 173,050,963 RGD:2290271
G TP53 tumor protein p53 JBrowse link 17 7,668,402 7,687,550 RGD:2290271
T follicular helper cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G FOXP1 forkhead box P1 JBrowse link 3 70,952,817 71,583,989 RGD:2290271
G GPR183 G protein-coupled receptor 183 JBrowse link 13 99,294,273 99,307,399 RGD:2290271
G RC3H1 ring finger and CCCH-type domains 1 JBrowse link 1 173,931,084 174,022,357 RGD:2290271
G RC3H2 ring finger and CCCH-type domains 2 JBrowse link 9 122,844,556 122,905,359 RGD:2290271
T-helper 1 cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G HMGB1 high mobility group box 1 JBrowse link 13 30,456,704 30,617,597 RGD:2290271
G IL18R1 interleukin 18 receptor 1 JBrowse link 2 102,355,796 102,398,777 RGD:2290271
G LEF1 lymphoid enhancer binding factor 1 JBrowse link 4 108,047,545 108,168,956 RGD:2290271
G RELB RELB proto-oncogene, NF-kB subunit JBrowse link 19 45,001,449 45,038,194 RGD:2290271
G SEMA4A semaphorin 4A JBrowse link 1 156,149,672 156,177,751 RGD:2290271
G TMEM98 transmembrane protein 98 JBrowse link 17 32,927,910 32,944,315 RGD:2290271
T-helper 1 cell lineage commitment term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G MTOR mechanistic target of rapamycin kinase JBrowse link 1 11,106,535 11,273,497 RGD:2290271
G SPN sialophorin JBrowse link 16 29,662,950 29,670,876 RGD:2290271
G STAT6 signal transducer and activator of transcription 6 JBrowse link 12 57,095,408 57,111,413 RGD:2290271
T-helper 17 cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BATF basic leucine zipper ATF-like transcription factor JBrowse link 14 75,522,469 75,546,992 RGD:2290271
G RORA RAR related orphan receptor A JBrowse link 15 60,488,284 61,229,302 RGD:2290271
G RORC RAR related orphan receptor C JBrowse link 1 151,806,071 151,832,451 RGD:2290271
T-helper 17 cell lineage commitment term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BATF basic leucine zipper ATF-like transcription factor JBrowse link 14 75,522,469 75,546,992 RGD:2290271
G IL6 interleukin 6 JBrowse link 7 22,725,889 22,732,002 RGD:2290271
G IRF4 interferon regulatory factor 4 JBrowse link 6 391,752 411,443 RGD:2290271
G LY9 lymphocyte antigen 9 JBrowse link 1 160,796,112 160,828,256 RGD:2290271
G SLAMF6 SLAM family member 6 JBrowse link 1 160,485,030 160,523,263 RGD:2290271
G STAT3 signal transducer and activator of transcription 3 JBrowse link 17 42,313,324 42,388,502 RGD:2290271
T-helper 2 cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BATF basic leucine zipper ATF-like transcription factor JBrowse link 14 75,522,469 75,546,992 RGD:2290271
G BCL3 BCL3 transcription coactivator JBrowse link 19 44,742,620 44,760,044 RGD:2290271
G GATA3 GATA binding protein 3 JBrowse link 10 8,045,420 8,075,198 RGD:2290271
G IL4 interleukin 4 JBrowse link 5 132,673,986 132,682,678 RGD:2290271
T-helper cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ATP7A ATPase copper transporting alpha JBrowse link X 77,910,656 78,050,395 RGD:2290271
G IL12B interleukin 12B JBrowse link 5 159,314,780 159,330,487 RGD:2290271
G PTGER4 prostaglandin E receptor 4 JBrowse link 5 40,679,915 40,740,936 RGD:2290271
G RORC RAR related orphan receptor C JBrowse link 1 151,806,071 151,832,451 RGD:2290271
T-helper cell lineage commitment term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ZFPM1 zinc finger protein, FOG family member 1 JBrowse link 16 88,451,782 88,537,031 RGD:2290271

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18105
    immune system process 3316
      leukocyte activation 1330
        lymphocyte activation 776
          lymphocyte activation involved in immune response 186
            B cell activation involved in immune response + 78
            T cell activation involved in immune response + 106
            natural killer cell activation involved in immune response + 33
Path 2
Term Annotations click to browse term
  biological_process 18105
    cellular process 17122
      cell activation 1488
        cell activation involved in immune response 720
          leukocyte activation involved in immune response 716
            lymphocyte activation involved in immune response 186
              B cell activation involved in immune response + 78
              T cell activation involved in immune response + 106
              natural killer cell activation involved in immune response + 33
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.