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ONTOLOGY REPORT - ANNOTATIONS


Term:CD8-positive, alpha-beta intraepithelial T cell differentiation
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Accession:GO:0002300 term browser browse the term
Definition:The process in which a precursor cell type acquires the specialized features of a CD8-positive, alpha-beta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways.
Comment:Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
Synonyms:exact_synonym: CD8-positive, alpha-beta intraepithelial T lymphocyte differentiation
 related_synonym: CD8-positive, alpha-beta intraepithelial T cell development


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CD8-positive, alpha-beta intraepithelial T cell differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gpr18 G protein-coupled receptor 18 ISO MGI:MGI:5708707 (MGI:MGI:5629467|PMID:25348153) RGD PMID:25348153 MGI:MGI:5629467 NCBI chr15:108,323,157...108,326,907
Ensembl chr15:108,323,179...108,326,907
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Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20017
    immune system process 2838
      leukocyte activation 1058
        lymphocyte activation 871
          T cell activation 522
            T cell differentiation 289
              alpha-beta T cell differentiation 122
                CD8-positive, alpha-beta T cell differentiation 17
                  CD8-positive, alpha-beta intraepithelial T cell differentiation 1
Path 2
Term Annotations click to browse term
  biological_process 20017
    developmental process 6813
      anatomical structure development 6256
        multicellular organism development 5735
          system development 5272
            immune system development 1073
              hematopoietic or lymphoid organ development 1008
                hemopoiesis 956
                  leukocyte differentiation 595
                    lymphocyte differentiation 407
                      T cell differentiation 289
                        alpha-beta T cell differentiation 122
                          alpha-beta intraepithelial T cell differentiation 1
                            CD8-positive, alpha-beta intraepithelial T cell differentiation 1
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.