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ONTOLOGY REPORT - ANNOTATIONS


Term:CD8-positive, alpha-beta T cell differentiation involved in immune response
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Accession:GO:0002302 term browser browse the term
Definition:The process in which an antigenically naive CD8-positive, alpha-beta T cell acquires the specialized features of an effector, regulatory, or memory T cell as part of an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells.
Comment:Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
Synonyms:related_synonym: CD8-positive, alpha-beta T cell differentiation during immune response;   CD8-positive, alpha-beta T lymphocyte differentiation during immune response;   CD8-positive, alpha-beta intraepithelial T cell development


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CD8-positive, alpha-beta T cell differentiation involved in immune response term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eomes eomesodermin ISO
IBA
(PMID:17566017)
(MGI:MGI:4399030|PMID:14605368)
PMID:21873635
RGD PMID:14605368, PMID:17566017, PMID:21873635 MGI:MGI:4399030, RGD:13792537 NCBI chr 8:127,144,367...127,152,618
Ensembl chr 8:127,144,903...127,151,493
JBrowse link
G Ifng interferon gamma ISO (MGI:MGI:3829555|PMID:17277142) RGD PMID:17277142 MGI:MGI:3829555 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20014
    immune system process 2837
      leukocyte activation 1057
        leukocyte activation involved in immune response 292
          lymphocyte activation involved in immune response 198
            T cell activation involved in immune response 113
              alpha-beta T cell activation involved in immune response 69
                alpha-beta T cell differentiation involved in immune response 67
                  CD8-positive, alpha-beta T cell differentiation involved in immune response 2
Path 2
Term Annotations click to browse term
  biological_process 20014
    developmental process 6812
      anatomical structure development 6256
        multicellular organism development 5735
          system development 5272
            immune system development 1073
              hematopoietic or lymphoid organ development 1008
                hemopoiesis 956
                  leukocyte differentiation 595
                    lymphocyte differentiation 407
                      T cell differentiation 289
                        alpha-beta T cell differentiation 122
                          alpha-beta T cell differentiation involved in immune response 67
                            CD8-positive, alpha-beta T cell differentiation involved in immune response 2
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.