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ONTOLOGY REPORT - ANNOTATIONS


Term:follicular B cell differentiation
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Accession:GO:0002316 term browser browse the term
Definition:The process in which a B cell in the spleen acquires the specialized features of a follicular B cell. Follicular B cells are major population of mature recirculating B cells in the spleen and are located in the B-cell follicle region.
Comment:Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
Synonyms:exact_synonym: follicular B lymphocyte differentiation
 related_synonym: follicular B cell development


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follicular B cell differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Plcg2 phospholipase C, gamma 2 ISO
IEA
MGI:MGI:2386100 (MGI:MGI:2679743|PMID:12928432)
GO_REF:0000107
RGD
Ensembl
PMID:12928432 GO_REF:0000107, MGI:MGI:2679743 NCBI chr19:50,039,410...50,173,543
Ensembl chr19:50,045,020...50,173,220
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Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20027
    immune system process 2844
      leukocyte activation 1058
        leukocyte activation involved in immune response 294
          lymphocyte activation involved in immune response 200
            B cell activation involved in immune response 88
              mature B cell differentiation involved in immune response 25
                follicular B cell differentiation 1
Path 2
Term Annotations click to browse term
  biological_process 20027
    developmental process 6827
      anatomical structure development 6269
        multicellular organism development 5744
          system development 5280
            animal organ development 4035
              hematopoietic or lymphoid organ development 1008
                hemopoiesis 956
                  leukocyte differentiation 597
                    lymphocyte differentiation 409
                      B cell differentiation 148
                        mature B cell differentiation 32
                          mature B cell differentiation involved in immune response 25
                            follicular B cell differentiation 1
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.