Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:plasma cell differentiation
go back to main search page
Accession:GO:0002317 term browser browse the term
Definition:The process in which a B cell acquires the specialized features of a plasma cell. A plasma cell is a lymphocyte which develops from a B cell and produces high amounts of antibody.
Comment:Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
Synonyms:related_synonym: plasma cell development


show annotations for term's descendants           Sort by:
 
plasma cell differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Itm2a integral membrane protein 2A ISO MGI:MGI:5645968 (MGI:MGI:5613782|PMID:24831988) RGD PMID:24831988 MGI:MGI:5613782 NCBI chr  X:78,490,872...78,496,814
Ensembl chr  X:78,490,866...78,496,847
JBrowse link
G Lgals1 galectin 1 ISO (MGI:MGI:5301217|PMID:21753146) RGD PMID:21753146 MGI:MGI:5301217 NCBI chr 7:120,153,184...120,156,290
Ensembl chr 7:120,153,184...120,156,289
JBrowse link
G Lgals8 galectin 8 ISO (MGI:MGI:5301217|PMID:21753146) RGD PMID:21753146 MGI:MGI:5301217 NCBI chr17:66,487,451...66,515,316
Ensembl chr17:66,487,457...66,511,870
JBrowse link
G Nkx2-3 NK2 homeobox 3 ISO MGI:MGI:2448069 (MGI:MGI:1888604|PMID:10926756) RGD PMID:10926756 MGI:MGI:1888604 NCBI chr 1:263,361,238...263,371,043
Ensembl chr 1:263,367,266...263,370,219
JBrowse link
positive regulation of plasma cell differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Xbp1 X-box binding protein 1 ISO
ISS
(PMID:11460154)
GO_REF:0000024
RGD
UniProt
PMID:11460154 GO_REF:0000024 NCBI chr14:85,753,736...85,758,820
Ensembl chr14:85,753,760...85,758,145
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20014
    immune system process 2837
      leukocyte activation 1057
        leukocyte activation involved in immune response 292
          lymphocyte activation involved in immune response 198
            B cell activation involved in immune response 86
              mature B cell differentiation involved in immune response 22
                plasma cell differentiation 5
                  negative regulation of plasma cell differentiation 0
                  positive regulation of plasma cell differentiation 1
                  regulation of plasma cell differentiation + 1
Path 2
Term Annotations click to browse term
  biological_process 20014
    developmental process 6812
      anatomical structure development 6256
        multicellular organism development 5735
          system development 5272
            animal organ development 4027
              hematopoietic or lymphoid organ development 1008
                hemopoiesis 956
                  leukocyte differentiation 595
                    lymphocyte differentiation 407
                      B cell differentiation 145
                        mature B cell differentiation 29
                          mature B cell differentiation involved in immune response 22
                            plasma cell differentiation 5
                              negative regulation of plasma cell differentiation 0
                              positive regulation of plasma cell differentiation 1
                              regulation of plasma cell differentiation + 1
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.