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ONTOLOGY REPORT - ANNOTATIONS


Term:memory B cell differentiation
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Accession:GO:0002319 term browser browse the term
Definition:The process in which a B cell acquires the specialized features of a memory B cell. Memory B cells are cells that can respond rapidly to antigen re-exposure by production of high-affinity antibody.
Comment:Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
Synonyms:exact_synonym: memory B-lymphocyte differentiation
 related_synonym: memory B cell development


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memory B cell differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G St3gal1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 ISO (MGI:MGI:2387354|PMID:10755614) RGD PMID:10755614 MGI:MGI:2387354 NCBI chr 7:107,895,045...107,963,158
Ensembl chr 7:107,895,045...107,963,142
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Term paths to the root
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Term Annotations click to browse term
  biological_process 20027
    immune system process 2844
      immunological memory process 12
        immunological memory formation process 9
          memory B cell differentiation 1
Path 2
Term Annotations click to browse term
  biological_process 20027
    developmental process 6827
      anatomical structure development 6269
        multicellular organism development 5744
          system development 5280
            immune system development 1073
              hematopoietic or lymphoid organ development 1008
                hemopoiesis 956
                  leukocyte differentiation 597
                    lymphocyte differentiation 409
                      B cell differentiation 148
                        mature B cell differentiation 32
                          mature B cell differentiation involved in immune response 25
                            memory B cell differentiation 1
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.