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ONTOLOGY REPORT - ANNOTATIONS


Term:T cell lineage commitment
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Accession:GO:0002360 term browser browse the term
Definition:The process in which a lymphoid progenitor cell becomes committed to becoming any type of T cell.
Synonyms:exact_synonym: T-lymphocyte lineage commitment


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T cell lineage commitment term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bcl2 BCL2, apoptosis regulator JBrowse link 13 26,605,426 26,769,374 RGD:1624291
G Foxn1 forkhead box N1 JBrowse link 10 65,621,142 65,634,666 RGD:1624291
G Il7 interleukin 7 JBrowse link 2 96,427,884 96,474,979 RGD:1624291
RGD:1600115
G Prkdc protein kinase, DNA-activated, catalytic subunit JBrowse link 11 89,293,547 89,510,948 RGD:1624291
G Rag2 recombination activating 2 JBrowse link 3 91,191,837 91,200,134 RGD:1624291
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:1624291
alpha-beta T cell lineage commitment term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Rhoa ras homolog family member A JBrowse link 8 117,082,440 117,116,244 RGD:1624291
CD4-positive or CD8-positive, alpha-beta T cell lineage commitment term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Braf B-Raf proto-oncogene, serine/threonine kinase JBrowse link 4 67,389,331 67,520,549 RGD:1624291
G Cyld CYLD lysine 63 deubiquitinase JBrowse link 19 19,264,984 19,323,817 RGD:1624291
RGD:1600115
G Shh sonic hedgehog signaling molecule JBrowse link 4 718,538 727,691 RGD:1624291
RGD:1600115
CD4-positive, alpha-beta T cell lineage commitment term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Tox thymocyte selection-associated high mobility group box JBrowse link 5 19,892,698 20,189,721 RGD:1624291
CD4-positive, CD25-positive, alpha-beta regulatory T cell lineage commitment term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Tox thymocyte selection-associated high mobility group box JBrowse link 5 19,892,698 20,189,721 RGD:1624291
CD8-positive, alpha-beta T cell lineage commitment term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bcl2 BCL2, apoptosis regulator JBrowse link 13 26,605,426 26,769,374 RGD:1624291
RGD:1600115
G Tox thymocyte selection-associated high mobility group box JBrowse link 5 19,892,698 20,189,721 RGD:1624291
gamma-delta T cell lineage commitment term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Olr292 olfactory receptor 292 JBrowse link 1 212,714,092 212,886,388 RGD:1600115
negative regulation of T-helper 17 cell lineage commitment term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Loxl3 lysyl oxidase-like 3 JBrowse link 4 113,866,782 113,883,713 RGD:1624291
G Tbx21 T-box transcription factor 21 JBrowse link 10 85,032,799 85,049,331 RGD:1624291
G Tnfsf18 TNF superfamily member 18 JBrowse link 13 79,378,412 79,388,687 RGD:1624291
NK T cell lineage commitment term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Tox thymocyte selection-associated high mobility group box JBrowse link 5 19,892,698 20,189,721 RGD:1624291
positive regulation of T-helper 17 cell lineage commitment term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Il23a interleukin 23 subunit alpha JBrowse link 7 2,710,609 2,712,723 RGD:1624291
RGD:13792537
T-helper 1 cell lineage commitment term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Il4 interleukin 4 JBrowse link 10 38,963,979 38,969,531 RGD:1624291
G Mtor mechanistic target of rapamycin kinase JBrowse link 5 165,263,813 165,373,967 RGD:1624291
G Spn sialophorin JBrowse link 1 198,572,999 198,585,664 RGD:1600115
RGD:1624291
G Stat6 signal transducer and activator of transcription 6 JBrowse link 7 70,946,228 70,963,542 RGD:1624291
T-helper 17 cell lineage commitment term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Batf basic leucine zipper ATF-like transcription factor JBrowse link 6 109,562,415 109,584,541 RGD:1600115
RGD:1624291
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:1624291
RGD:1600115
G Irf4 interferon regulatory factor 4 JBrowse link 17 34,886,746 34,905,191 RGD:1624291
G Ly9 lymphocyte antigen 9 JBrowse link 13 90,002,779 90,022,346 RGD:1624291
G Otud5 OTU deubiquitinase 5 JBrowse link X 15,471,212 15,504,372 RGD:1624291
G Slamf6 SLAM family member 6 JBrowse link 13 90,300,160 90,321,781 RGD:1624291
G Stat3 signal transducer and activator of transcription 3 JBrowse link 10 88,790,401 88,842,263 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19578
    cellular process 18362
      cellular developmental process 4347
        cell fate commitment 288
          T cell lineage commitment 27
            CD4-positive or CD8-positive, alpha-beta T cell lineage commitment + 20
            alpha-beta T cell lineage commitment + 18
            gamma-delta T cell lineage commitment 1
Path 2
Term Annotations click to browse term
  biological_process 19578
    developmental process 6697
      anatomical structure development 6155
        multicellular organism development 5623
          system development 5157
            immune system development 1046
              hematopoietic or lymphoid organ development 982
                hemopoiesis 930
                  leukocyte differentiation 575
                    lymphocyte differentiation 392
                      T cell differentiation 279
                        T cell lineage commitment 27
                          CD4-positive or CD8-positive, alpha-beta T cell lineage commitment + 20
                          alpha-beta T cell lineage commitment + 18
                          gamma-delta T cell lineage commitment 1
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.