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ONTOLOGY REPORT - ANNOTATIONS


Term:immunoglobulin production involved in immunoglobulin mediated immune response
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Accession:GO:0002381 term browser browse the term
Definition:The appearance of immunoglobulin due to biosynthesis or secretion following a cellular stimulus during an immune response, resulting in an increase in its intracellular or extracellular levels.
Synonyms:related_synonym: antibody production during immune response;   immunoglobulin production during immune response;   immunoglobulin production involved in immune response


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immunoglobulin production involved in immunoglobulin mediated immune response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fgl2 fibrinogen-like 2 JBrowse link 4 10,323,598 10,329,241 RGD:1600115
RGD:1624291
G Gapt Grb2-binding adaptor protein, transmembrane JBrowse link 2 41,869,555 41,874,130 RGD:1624291
RGD:13792537
G Nod2 nucleotide-binding oligomerization domain containing 2 JBrowse link 19 19,342,061 19,389,366 RGD:1624291
G RT1-Bb RT1 class II, locus Bb JBrowse link 20 4,043,726 4,049,367 RGD:1624291
G RT1-Db1 RT1 class II, locus Db1 JBrowse link 20 4,087,621 4,097,190 RGD:1624291
B cell affinity maturation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Btk Bruton tyrosine kinase JBrowse link X 105,360,922 105,390,580 RGD:1624291
RGD:1600115
G RT1-Bb RT1 class II, locus Bb JBrowse link 20 4,043,726 4,049,367 RGD:1624291
RGD:1600115
immunoglobulin biosynthetic process involved in immune response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Trex1 three prime repair exonuclease 1 JBrowse link 8 117,796,127 117,797,427 RGD:1624291
RGD:1600115
immunoglobulin production in mucosal tissue term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gcnt3 glucosaminyl (N-acetyl) transferase 3, mucin type JBrowse link 8 76,449,078 76,459,431 RGD:1624291
RGD:1600115
G Tnfsf13 TNF superfamily member 13 JBrowse link 10 56,286,964 56,290,680 RGD:1624291
immunoglobulin secretion involved in immune response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Crlf2 cytokine receptor-like factor 2 JBrowse link 14 1,456,843 1,461,543 RGD:1624291
G Pou2f2 POU class 2 homeobox 2 JBrowse link 1 81,966,791 82,049,116 RGD:1624291
isotype switching term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aicda activation-induced cytidine deaminase JBrowse link 4 155,359,909 155,371,104 RGD:1624291
RGD:1600115
G Atad5 ATPase family, AAA domain containing 5 JBrowse link 10 67,427,042 67,475,825 RGD:1600115
RGD:1624291
G Batf basic leucine zipper ATF-like transcription factor JBrowse link 6 109,562,415 109,584,541 RGD:1600115
RGD:1624291
G Cd40lg CD40 ligand JBrowse link X 159,703,703 159,714,886 RGD:1600115
RGD:1624291
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit JBrowse link 1 80,256,973 80,268,198 RGD:1624291
RGD:1600115
G Exo1 exonuclease 1 JBrowse link 13 93,936,989 93,962,749 RGD:1624291
RGD:1600115
G Exosc3 exosome component 3 JBrowse link 5 60,866,498 60,871,734 RGD:1624291
G Exosc6 exosome component 6 JBrowse link 19 43,190,879 43,193,164 RGD:1624291
RGD:1600115
G Lig4 DNA ligase 4 JBrowse link 16 85,331,771 85,339,496 RGD:1624291
RGD:1600115
G Mlh1 mutL homolog 1 JBrowse link 8 119,486,655 119,523,716 RGD:1624291
RGD:1600115
G Msh2 mutS homolog 2 JBrowse link 6 11,215,951 11,274,916 RGD:1600115
RGD:1624291
G Msh6 mutS homolog 6 JBrowse link 6 11,644,565 11,662,389 RGD:1600115
RGD:1624291
G Nbn nibrin JBrowse link 5 29,622,347 29,656,877 RGD:1600115
RGD:1624291
G Rnf168 ring finger protein 168 JBrowse link 11 71,721,242 71,743,421 RGD:1624291
RGD:1600115
G Rnf8 ring finger protein 8 JBrowse link 20 8,285,380 8,309,858 RGD:1624291
RGD:1600115
G Swap70 switching B-cell complex subunit SWAP70 JBrowse link 1 174,862,683 174,924,101 RGD:1624291
RGD:1600115
G Ung uracil-DNA glycosylase JBrowse link 12 48,246,593 48,255,547 RGD:1624291
RGD:1600115
G Xrcc4 X-ray repair cross complementing 4 JBrowse link 2 18,674,496 18,927,463 RGD:1624291
isotype switching to IgA isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ccr6 C-C motif chemokine receptor 6 JBrowse link 1 53,063,380 53,087,519 RGD:1624291
RGD:1600115
isotype switching to IgG isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hspd1 heat shock protein family D (Hsp60) member 1 JBrowse link 9 61,680,529 61,691,202 RGD:1624291
negative regulation of isotype switching term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Parp3 poly (ADP-ribose) polymerase family, member 3 JBrowse link 8 115,173,440 115,179,543 RGD:1600115
RGD:1624291
negative regulation of isotype switching to IgA isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Da2-19 uncharacterized LOC302729 JBrowse link X 48,196,789 48,213,506 RGD:1600115
G Thoc1 THO complex 1 JBrowse link 18 1,142,540 1,177,084 RGD:1624291
negative regulation of isotype switching to IgE isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bcl6 BCL6, transcription repressor JBrowse link 11 80,255,790 80,279,075 RGD:1624291
RGD:1600115
G Foxp3 forkhead box P3 JBrowse link X 15,753,175 15,768,648 RGD:1624291
RGD:1600115
G Ndfip1 Nedd4 family interacting protein 1 JBrowse link 18 31,574,759 31,625,286 RGD:1624291
RGD:1600115
positive regulation of immunoglobulin production in mucosal tissue term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G LOC688282 hypothetical protein LOC688282 JBrowse link 10 106,800,040 106,810,153 RGD:1624291
G Xcl1 X-C motif chemokine ligand 1 JBrowse link 13 83,199,402 83,202,845 RGD:1624291
RGD:1600115
positive regulation of interleukin-4-dependent isotype switching to IgE isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Tnfsf4 TNF superfamily member 4 JBrowse link 13 79,269,973 79,293,775 RGD:1624291
RGD:1600115
positive regulation of isotype switching term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Exosc3 exosome component 3 JBrowse link 5 60,866,498 60,871,734 RGD:1624291
G Exosc6 exosome component 6 JBrowse link 19 43,190,879 43,193,164 RGD:1624291
RGD:1600115
G Kmt5b lysine methyltransferase 5B JBrowse link 1 219,000,844 219,050,211 RGD:1600115
G Kmt5c lysine methyltransferase 5C JBrowse link 1 72,666,662 72,674,271 RGD:1600115
G Mad2l2 mitotic arrest deficient 2 like 2 JBrowse link 5 164,943,183 164,956,255 RGD:1600115
RGD:1624291
G Paxip1 PAX interacting protein 1 JBrowse link 4 3,956,931 4,008,326 RGD:1624291
G Rif1 replication timing regulatory factor 1 JBrowse link 3 37,599,540 37,648,818 RGD:1624291
RGD:1600115
G Shld1 shieldin complex subunit 1 JBrowse link 3 125,318,682 125,396,705 RGD:1600115
RGD:1624291
G Shld2 shieldin complex subunit 2 JBrowse link 16 10,570,307 10,661,528 RGD:1624291
RGD:1600115
G Tfrc transferrin receptor JBrowse link 11 71,397,423 71,419,263 RGD:1624291
RGD:1600115
G Tp53bp1 tumor protein p53 binding protein 1 JBrowse link 3 113,160,030 113,259,701 RGD:1624291
RGD:1600115
positive regulation of isotype switching to IgA isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mlh1 mutL homolog 1 JBrowse link 8 119,486,655 119,523,716 RGD:1600115
RGD:1624291
G Msh2 mutS homolog 2 JBrowse link 6 11,215,951 11,274,916 RGD:1600115
RGD:1624291
G Nsd2 nuclear receptor binding SET domain protein 2 JBrowse link 14 82,119,210 82,196,501 RGD:1624291
RGD:1600115
G Pms2 PMS1 homolog 2, mismatch repair system component JBrowse link 12 12,714,394 12,738,654 RGD:1624291
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:1624291
RGD:1600115
G Tnfsf13 TNF superfamily member 13 JBrowse link 10 56,286,964 56,290,680 RGD:1624291
RGD:1600115
positive regulation of isotype switching to IgE isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Clcf1 cardiotrophin-like cytokine factor 1 JBrowse link 1 219,468,866 219,472,445 RGD:1624291
G Il4 interleukin 4 JBrowse link 10 38,963,979 38,969,531 RGD:1624291
G Stat6 signal transducer and activator of transcription 6 JBrowse link 7 70,946,228 70,963,542 RGD:1624291
RGD:1600115
positive regulation of isotype switching to IgG isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atad5 ATPase family, AAA domain containing 5 JBrowse link 10 67,427,042 67,475,825 RGD:1624291
RGD:1600115
G Cd28 Cd28 molecule JBrowse link 9 67,546,408 67,573,858 RGD:1624291
RGD:1600115
G Cd40 CD40 molecule JBrowse link 3 161,519,789 161,534,943 RGD:1624291
RGD:1600115
G Ifng interferon gamma JBrowse link 7 61,337,383 61,341,419 RGD:1624291
RGD:1600115
G Il2 interleukin 2 JBrowse link 2 123,847,150 123,851,854 RGD:1624291
G Il4 interleukin 4 JBrowse link 10 38,963,979 38,969,531 RGD:1624291
G Mlh1 mutL homolog 1 JBrowse link 8 119,486,655 119,523,716 RGD:1600115
RGD:1624291
G Msh2 mutS homolog 2 JBrowse link 6 11,215,951 11,274,916 RGD:1600115
RGD:1624291
G Pagr1 Paxip1-associated glutamate-rich protein 1 JBrowse link 1 198,448,790 198,451,078 RGD:1624291
G Paxip1 PAX interacting protein 1 JBrowse link 4 3,956,931 4,008,326 RGD:1624291
G Pms2 PMS1 homolog 2, mismatch repair system component JBrowse link 12 12,714,394 12,738,654 RGD:1624291
G Ptprc protein tyrosine phosphatase, receptor type, C JBrowse link 13 55,061,561 55,174,150 RGD:1624291
G Tbx21 T-box transcription factor 21 JBrowse link 10 85,032,799 85,049,331 RGD:1624291
RGD:1600115
regulation of isotype switching term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aplf aprataxin and PNKP like factor JBrowse link 4 119,514,822 119,568,764 RGD:1624291
G Mir181b1 microRNA 181b-1 JBrowse link 13 54,952,903 54,953,012 RGD:1624291
G Mir181b2 microRNA 181b-2 JBrowse link 3 23,151,455 23,151,542 RGD:1624291
G Supt6h SPT6 homolog, histone chaperone and transcription elongation factor JBrowse link 10 65,470,470 65,507,581 RGD:1624291
RGD:1600115
regulation of isotype switching to IgG isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Foxp3 forkhead box P3 JBrowse link X 15,753,175 15,768,648 RGD:1624291
RGD:1600115
G Il27ra interleukin 27 receptor subunit alpha JBrowse link 19 25,151,835 25,163,995 RGD:1624291
RGD:1600115
G Ndfip1 Nedd4 family interacting protein 1 JBrowse link 18 31,574,759 31,625,286 RGD:1624291
RGD:1600115
somatic recombination of immunoglobulin genes involved in immune response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mlh1 mutL homolog 1 JBrowse link 8 119,486,655 119,523,716 RGD:1624291
G Msh2 mutS homolog 2 JBrowse link 6 11,215,951 11,274,916 RGD:1624291
RGD:13792537

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19245
    immune system process 2631
      production of molecular mediator of immune response 361
        immunoglobulin production 258
          immunoglobulin production involved in immunoglobulin mediated immune response 67
            B cell affinity maturation + 2
            immunoglobulin biosynthetic process involved in immune response 1
            immunoglobulin production in mucosal tissue + 4
            immunoglobulin secretion involved in immune response 2
            somatic diversification of immunoglobulins involved in immune response + 55
Path 2
Term Annotations click to browse term
  biological_process 19245
    immune system process 2631
      immune effector process 836
        leukocyte mediated immunity 479
          lymphocyte mediated immunity 385
            B cell mediated immunity 231
              immunoglobulin mediated immune response 227
                immunoglobulin production involved in immunoglobulin mediated immune response 67
                  B cell affinity maturation + 2
                  immunoglobulin biosynthetic process involved in immune response 1
                  immunoglobulin production in mucosal tissue + 4
                  immunoglobulin secretion involved in immune response 2
                  somatic diversification of immunoglobulins involved in immune response + 55
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.