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ONTOLOGY REPORT - ANNOTATIONS


Term:immunoglobulin production involved in immunoglobulin mediated immune response
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Accession:GO:0002381 term browser browse the term
Definition:The appearance of immunoglobulin due to biosynthesis or secretion following a cellular stimulus during an immune response, resulting in an increase in its intracellular or extracellular levels.
Synonyms:related_synonym: antibody production during immune response;   immunoglobulin production during immune response;   immunoglobulin production involved in immune response


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immunoglobulin production involved in immunoglobulin mediated immune response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G FGL2 fibrinogen like 2 JBrowse link 18 17,328,794 17,335,429 RGD:13508589
G GAPT GRB2 binding adaptor protein, transmembrane JBrowse link 2 45,383,244 45,402,649 RGD:13508589
B cell affinity maturation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G LOC100856137 HLA class II histocompatibility antigen, DQ beta 2 chain JBrowse link 12 2,244,820 2,250,822 RGD:13508589
immunoglobulin production in mucosal tissue term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type JBrowse link 30 24,481,698 24,487,855 RGD:13508589
isotype switching term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ATAD5 ATPase family AAA domain containing 5 JBrowse link 9 40,869,778 40,917,976 RGD:13508589
G BATF basic leucine zipper ATF-like transcription factor JBrowse link 8 48,537,036 48,561,154 RGD:13508589
G CD40LG CD40 ligand JBrowse link X 107,001,421 107,023,007 RGD:13508589
G EXO1 exonuclease 1 JBrowse link 7 33,237,124 33,268,835 RGD:13508589
G EXOSC3 exosome component 3 JBrowse link 11 54,072,993 54,079,024 RGD:13508589
G LIG4 DNA ligase 4 JBrowse link 22 56,980,333 56,987,636 RGD:13508589
G MLH1 mutL homolog 1 JBrowse link 23 6,889,108 6,938,117 RGD:13508589
G MSH2 mutS homolog 2 JBrowse link 10 49,517,448 49,594,001 RGD:13508589
G MSH6 mutS homolog 6 JBrowse link 10 49,825,330 49,838,036 RGD:13508589
G NBN nibrin JBrowse link 29 35,416,093 35,477,569 RGD:13508589
G SWAP70 switching B cell complex subunit SWAP70 JBrowse link 21 32,910,547 32,985,617 RGD:13508589
isotype switching to IgG isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G HSPD1 heat shock protein family D (Hsp60) member 1 JBrowse link 37 7,010,421 7,025,912 RGD:13508589
negative regulation of isotype switching term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PARP3 poly(ADP-ribose) polymerase family member 3 JBrowse link 20 37,767,336 37,774,269 RGD:13508589
negative regulation of isotype switching to IgA isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G THOC1 THO complex 1 JBrowse link 7 67,082,100 67,136,592 RGD:13508589
negative regulation of isotype switching to IgE isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G BCL6 BCL6 transcription repressor JBrowse link 34 20,112,302 20,135,705 RGD:13508589
positive regulation of isotype switching term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G EXOSC3 exosome component 3 JBrowse link 11 54,072,993 54,079,024 RGD:13508589
G HMCES 5-hydroxymethylcytosine binding, ES cell specific JBrowse link 20 2,808,687 2,831,123 RGD:13508589
G KMT5B lysine methyltransferase 5B JBrowse link 18 49,655,783 49,691,899 RGD:13508589
G KMT5C lysine methyltransferase 5C JBrowse link 1 102,334,687 102,342,090 RGD:13508589
G MAD2L2 mitotic arrest deficient 2 like 2 JBrowse link 2 84,539,724 84,549,402 RGD:13508589
G RIF1 replication timing regulatory factor 1 JBrowse link 19 52,661,278 52,711,969 RGD:13508589
G SHLD1 shieldin complex subunit 1 JBrowse link 24 15,957,863 16,037,336 RGD:13508589
G TFRC transferrin receptor JBrowse link 33 29,206,024 29,237,221 RGD:13508589
G TP53BP1 tumor protein p53 binding protein 1 JBrowse link 30 10,263,650 10,362,646 RGD:13508589
positive regulation of isotype switching to IgA isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G B9D2 B9 domain containing 2 JBrowse link 1 112,621,832 112,627,726 RGD:13508589
G MLH1 mutL homolog 1 JBrowse link 23 6,889,108 6,938,117 RGD:13508589
G MSH2 mutS homolog 2 JBrowse link 10 49,517,448 49,594,001 RGD:13508589
G NSD2 nuclear receptor binding SET domain protein 2 JBrowse link 3 62,164,888 62,228,006 RGD:13508589
G TGFB1 transforming growth factor beta 1 JBrowse link 1 112,629,476 112,643,885 RGD:13508589
G TNFSF13 TNF superfamily member 13 JBrowse link 5 32,482,723 32,484,790 RGD:13508589
positive regulation of isotype switching to IgE isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G IL4 interleukin 4 JBrowse link 11 20,972,693 20,981,539 RGD:13508589
positive regulation of isotype switching to IgG isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ATAD5 ATPase family AAA domain containing 5 JBrowse link 9 40,869,778 40,917,976 RGD:13508589
G CD40 CD40 molecule JBrowse link 24 33,352,992 33,383,488 RGD:13508589
G IL2 interleukin 2 JBrowse link 19 17,750,780 17,756,394 RGD:13508589
G IL4 interleukin 4 JBrowse link 11 20,972,693 20,981,539 RGD:13508589
G MLH1 mutL homolog 1 JBrowse link 23 6,889,108 6,938,117 RGD:13508589
G MSH2 mutS homolog 2 JBrowse link 10 49,517,448 49,594,001 RGD:13508589
G PAXIP1 PAX interacting protein 1 JBrowse link 16 18,066,289 18,116,007 RGD:13508589
G TBX21 T-box transcription factor 21 JBrowse link 9 24,077,752 24,086,560 RGD:13508589
regulation of isotype switching term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G APLF aprataxin and PNKP like factor JBrowse link 10 67,454,500 67,522,659 RGD:13508589
G SUPT6H SPT6 homolog, histone chaperone and transcription elongation factor JBrowse link 9 42,859,154 42,896,044 RGD:13508589
somatic recombination of immunoglobulin genes involved in immune response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G MSH2 mutS homolog 2 JBrowse link 10 49,517,448 49,594,001 RGD:13508589

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 14453
    immune system process 1450
      production of molecular mediator of immune response 133
        immunoglobulin production 72
          immunoglobulin production involved in immunoglobulin mediated immune response 38
            B cell affinity maturation + 1
            immunoglobulin biosynthetic process involved in immune response 0
            immunoglobulin production in mucosal tissue + 1
            immunoglobulin secretion involved in immune response 0
            somatic diversification of immunoglobulins involved in immune response + 34
Path 2
Term Annotations click to browse term
  biological_process 14453
    immune system process 1450
      immune effector process 407
        leukocyte mediated immunity 188
          lymphocyte mediated immunity 149
            B cell mediated immunity 66
              immunoglobulin mediated immune response 66
                immunoglobulin production involved in immunoglobulin mediated immune response 38
                  B cell affinity maturation + 1
                  immunoglobulin biosynthetic process involved in immune response 0
                  immunoglobulin production in mucosal tissue + 1
                  immunoglobulin secretion involved in immune response 0
                  somatic diversification of immunoglobulins involved in immune response + 34
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.