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ONTOLOGY REPORT - ANNOTATIONS


Term:natural killer cell mediated immune response to tumor cell
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Accession:GO:0002423 term browser browse the term
Definition:An immune response mediated by a natural killer cell triggered in response to the presence of a tumor cell.


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negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ceacam1 CEA cell adhesion molecule 1 JBrowse link 1 82,327,955 82,344,345 RGD:1624291
RGD:1600115
G Havcr2 hepatitis A virus cellular receptor 2 JBrowse link 10 31,561,838 31,590,624 RGD:1624291
G Klre1 killer cell lectin-like receptor, family E, member 1 JBrowse link 4 163,346,684 163,355,050 RGD:1299590
positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AABR07032888.1 RGD:13792537
G Cd226 CD226 molecule JBrowse link 18 86,299,392 86,394,772 RGD:1624291
RGD:13792537
G Crtam cytotoxic and regulatory T cell molecule JBrowse link 8 45,152,584 45,216,082 RGD:1624291
RGD:13792537
G Il12a interleukin 12A JBrowse link 2 165,076,945 165,083,996 RGD:1624291
RGD:1600115
G Il12b interleukin 12B JBrowse link 10 30,034,447 30,048,774 RGD:1624291
G Klrk1 killer cell lectin like receptor K1 JBrowse link 4 163,392,652 163,403,735 RGD:9685180
G Nectin2 nectin cell adhesion molecule 2 JBrowse link 1 80,631,449 80,666,617 RGD:1624291
RGD:13792537
G Pvr PVR cell adhesion molecule JBrowse link 1 80,820,306 80,835,712 RGD:1624291
RGD:13792537
G Rrlt similar to retinoic acid early transcript 1L JBrowse link 1 1,437,716 1,442,089 RGD:9685180
positive regulation of natural killer cell mediated immune response to tumor cell term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd160 CD160 molecule JBrowse link 2 198,933,681 198,965,380 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19578
    immune system process 2693
      immune response 1626
        immune response to tumor cell 29
          natural killer cell mediated immune response to tumor cell 13
            natural killer cell mediated cytotoxicity directed against tumor cell target + 12
            negative regulation of natural killer cell mediated immune response to tumor cell + 3
            positive regulation of natural killer cell mediated immune response to tumor cell + 10
            regulation of natural killer cell mediated immune response to tumor cell + 13
Path 2
Term Annotations click to browse term
  biological_process 19578
    response to stimulus 10490
      response to external stimulus 3136
        response to external biotic stimulus 1618
          response to other organism 1614
            defense response to other organism 1027
              innate immune response 733
                natural killer cell mediated immunity 71
                  natural killer cell mediated immune response to tumor cell 13
                    natural killer cell mediated cytotoxicity directed against tumor cell target + 12
                    negative regulation of natural killer cell mediated immune response to tumor cell + 3
                    positive regulation of natural killer cell mediated immune response to tumor cell + 10
                    regulation of natural killer cell mediated immune response to tumor cell + 13
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.