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ONTOLOGY REPORT - ANNOTATIONS


Term:Fc receptor mediated stimulatory signaling pathway
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Accession:GO:0002431 term browser browse the term
Definition:A series of molecular signals generated as a consequence of a the binding of the Fc portion of an immunoglobulin by an Fc receptor capable of activating or perpetuating an immune response. The Fc portion of an immunoglobulin is its C-terminal constant region.
Synonyms:exact_synonym: Fc receptor mediated stimulatory signalling pathway


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Fc receptor mediated stimulatory signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Blk BLK proto-oncogene, Src family tyrosine kinase JBrowse link 15 46,555,552 46,593,778 RGD:13792537
G Fcer1g Fc fragment of IgE receptor Ig JBrowse link 13 89,601,894 89,606,326 RGD:1624291
RGD:13792537
G Lyn LYN proto-oncogene, Src family tyrosine kinase JBrowse link 5 16,526,058 16,642,648 RGD:1624291
RGD:13792537
RGD:1600115
Fc-gamma receptor signaling pathway involved in phagocytosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fcgr2b Fc fragment of IgG receptor IIb JBrowse link 13 89,329,298 89,343,916 RGD:1624291
G Myo1g myosin IG JBrowse link 14 86,781,243 86,796,393 RGD:1624291
negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Appl1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 JBrowse link 16 2,560,103 2,602,035 RGD:1624291
G Cd47 Cd47 molecule JBrowse link 11 53,511,485 53,575,754 RGD:13792533
positive regulation of Fc receptor mediated stimulatory signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AABR07032888.1 RGD:13792537
G Cd226 CD226 molecule JBrowse link 18 86,299,392 86,394,772 RGD:1624291
RGD:13792537
G Lyn LYN proto-oncogene, Src family tyrosine kinase JBrowse link 5 16,526,058 16,642,648 RGD:1578516
positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Appl2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 JBrowse link 7 26,256,179 26,306,128 RGD:1624291
G Ptprc protein tyrosine phosphatase, receptor type, C JBrowse link 13 55,061,561 55,174,150 RGD:1624291
G Ptprj protein tyrosine phosphatase, receptor type, J JBrowse link 3 79,233,519 79,390,956 RGD:1624291
G Rap1a RAP1A, member of RAS oncogene family JBrowse link 2 208,193,950 208,215,186 RGD:9835043
G Rapgef1 Rap guanine nucleotide exchange factor 1 JBrowse link 3 8,189,594 8,307,077 RGD:9835043
positive regulation of mast cell activation by Fc-epsilon receptor signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 JBrowse link 5 63,781,801 63,822,890 RGD:1624291
RGD:1600115
regulation of Fc receptor mediated stimulatory signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Csk C-terminal Src kinase JBrowse link 8 62,405,714 62,424,707 RGD:2303720
RGD:13792537
G Plscr1 phospholipid scramblase 1 JBrowse link 8 99,625,523 99,645,882 RGD:2303650
G Rabgef1 RAB guanine nucleotide exchange factor 1 JBrowse link 12 29,960,132 30,004,727 RGD:1624291
regulation of Fc-gamma receptor signaling pathway involved in phagocytosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fcgr2a Fc fragment of IgG receptor IIa JBrowse link 13 91,146,878 91,163,691 RGD:11041001
RGD:2293335

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19858
    immune system process 2798
      activation of immune response 418
        immune response-activating signal transduction 320
          immune response-activating cell surface receptor signaling pathway 319
            Fc receptor mediated stimulatory signaling pathway 19
              Fc-gamma receptor signaling pathway involved in phagocytosis + 10
              positive regulation of Fc receptor mediated stimulatory signaling pathway + 8
              positive regulation of mast cell activation by Fc-epsilon receptor signaling pathway 1
              regulation of Fc receptor mediated stimulatory signaling pathway + 14
Path 2
Term Annotations click to browse term
  biological_process 19858
    biological regulation 13636
      regulation of biological process 12959
        positive regulation of biological process 6625
          positive regulation of immune system process 1060
            positive regulation of immune response 672
              activation of immune response 418
                immune response-activating signal transduction 320
                  immune response-activating cell surface receptor signaling pathway 319
                    Fc receptor mediated stimulatory signaling pathway 19
                      Fc-gamma receptor signaling pathway involved in phagocytosis + 10
                      positive regulation of Fc receptor mediated stimulatory signaling pathway + 8
                      positive regulation of mast cell activation by Fc-epsilon receptor signaling pathway 1
                      regulation of Fc receptor mediated stimulatory signaling pathway + 14
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.