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ONTOLOGY REPORT - ANNOTATIONS


Term:immune response-regulating cell surface receptor signaling pathway involved in phagocytosis
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Accession:GO:0002433 term browser browse the term
Definition:An immune response-regulating cell surface receptor signaling pathway that contributes to the endocytic engulfment of external particulate material by phagocytes.
Synonyms:exact_synonym: immune response-regulating cell surface receptor signalling pathway involved in phagocytosis;   phagocytosis triggered by activation of immune response cell surface activating receptor


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Fc-gamma receptor signaling pathway involved in phagocytosis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fcgr2b Fc fragment of IgG receptor IIb ISO (PMID:2142460) RGD PMID:2142460 NCBI chr13:89,329,298...89,343,916
Ensembl chr13:89,327,794...89,433,815
JBrowse link
G Myo1g myosin IG ISO (MGI:MGI:5586792|PMID:23038771) RGD PMID:23038771 MGI:MGI:5586792 NCBI chr14:86,781,243...86,796,393
Ensembl chr14:86,781,202...86,796,378
JBrowse link
negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Appl1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 ISO (MGI:MGI:6271154|PMID:25568335) RGD PMID:25568335 MGI:MGI:6271154 NCBI chr16:2,560,103...2,602,035
Ensembl chr16:2,563,520...2,602,103
JBrowse link
G Cd47 Cd47 molecule IMP PMID:21401967 ARUK-UCL PMID:21401967 RGD:13792533 NCBI chr11:53,511,485...53,575,754
Ensembl chr11:53,514,595...53,575,175
JBrowse link
positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Appl2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 ISO (MGI:MGI:6271154|PMID:25568335) RGD PMID:25568335 MGI:MGI:6271154 NCBI chr 7:26,256,179...26,306,128
Ensembl chr 7:26,256,459...26,306,126
JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C ISO UniProtKB:Q64455 (MGI:MGI:3774343|PMID:18249142) RGD PMID:18249142 MGI:MGI:3774343 NCBI chr13:55,061,561...55,174,150
Ensembl chr13:55,061,562...55,173,692
JBrowse link
G Ptprj protein tyrosine phosphatase, receptor type, J ISO UniProtKB:P06800 (MGI:MGI:3774343|PMID:18249142) RGD PMID:18249142 MGI:MGI:3774343 NCBI chr 3:79,233,519...79,390,956
Ensembl chr 3:79,233,525...79,390,956
JBrowse link
G Rap1a RAP1A, member of RAS oncogene family IMP RGD PMID:18832707 RGD:9835043 NCBI chr 2:208,193,950...208,215,186
Ensembl chr 2:208,193,954...208,215,187
JBrowse link
G Rapgef1 Rap guanine nucleotide exchange factor 1 IMP RGD PMID:18832707 RGD:9835043 NCBI chr 3:8,189,594...8,307,077
Ensembl chr 3:8,192,575...8,304,976
JBrowse link
regulation of Fc-gamma receptor signaling pathway involved in phagocytosis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fcgr2a Fc fragment of IgG receptor IIa IMP RGD PMID:22184119, PMID:16482158 RGD:11041001, RGD:2293335 NCBI chr13:91,146,878...91,163,691
Ensembl chr13:91,168,973...91,198,036
Ensembl chr13:91,168,973...91,198,036
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20017
    immune system process 2838
      immune effector process 882
        immune response-regulating cell surface receptor signaling pathway involved in phagocytosis 10
          Fc-gamma receptor signaling pathway involved in phagocytosis + 10
Path 2
Term Annotations click to browse term
  biological_process 20017
    biological regulation 13767
      regulation of biological process 13081
        regulation of response to stimulus 4097
          regulation of immune response 865
            immune response-regulating signaling pathway 341
              immune response-regulating cell surface receptor signaling pathway 337
                immune response-regulating cell surface receptor signaling pathway involved in phagocytosis 10
                  Fc-gamma receptor signaling pathway involved in phagocytosis + 10
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.