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ONTOLOGY REPORT - ANNOTATIONS


Term:myeloid leukocyte mediated immunity
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Accession:GO:0002444 term browser browse the term
Definition:Any process involved in the carrying out of an immune response by a myeloid leukocyte.
Synonyms:exact_synonym: myeloid leucocyte immune effector process;   myeloid leucocyte mediated immunity;   myeloid leukocyte immune effector process


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antibody-dependent cellular cytotoxicity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fcgr1a Fc fragment of IgG receptor Ia JBrowse link 2 198,430,536 198,439,453 RGD:1624291
G Fcgr2a Fc fragment of IgG receptor IIa JBrowse link 13 91,146,878 91,163,691 RGD:1624291
G Ighg1 immunoglobulin heavy constant gamma 1 JBrowse link 6 139,140,572 139,784,388 RGD:1624291
basophil degranulation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pi4k2a phosphatidylinositol 4-kinase type 2 alpha JBrowse link 1 261,337,594 261,362,509 RGD:2306407
eosinophil degranulation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ccl3 C-C motif chemokine ligand 3 JBrowse link 10 70,869,516 70,871,066 RGD:1624291
RGD:1600115
G Vamp2 vesicle-associated membrane protein 2 JBrowse link 10 55,675,171 55,679,405 RGD:1624291
G Vamp7 vesicle-associated membrane protein 7 JBrowse link 12 18,996,566 19,033,714 RGD:8553828
RGD:1624291
G Vamp8 vesicle-associated membrane protein 8 JBrowse link 4 100,250,301 100,252,756 RGD:1624291
histamine secretion by mast cell term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AABR07053516.1 RGD:1600115
G Adora3 adenosine A3 receptor JBrowse link 2 208,336,909 208,379,217 RGD:1624291
G Btk Bruton tyrosine kinase JBrowse link X 105,360,922 105,390,580 RGD:1600535
G Lyn LYN proto-oncogene, Src family tyrosine kinase JBrowse link 5 16,526,058 16,642,648 RGD:1578516
G Snap23 synaptosome associated protein 23 JBrowse link 3 112,333,972 112,362,960 RGD:1624291
G Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta JBrowse link 7 75,573,553 75,598,295 RGD:1625716
mast cell degranulation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cbl Cbl proto-oncogene JBrowse link 8 48,481,256 48,564,775 RGD:11576314
G Chga chromogranin A JBrowse link 6 126,434,226 126,445,569 RGD:1600115
RGD:1624291
G Cplx2 complexin 2 JBrowse link 17 10,756,871 10,828,811 RGD:1600115
G Kit KIT proto-oncogene receptor tyrosine kinase JBrowse link 14 35,072,131 35,149,638 RGD:1624291
G Lat linker for activation of T cells JBrowse link 1 197,765,644 197,770,669 RGD:1600115
G Lat2 linker for activation of T cells family, member 2 JBrowse link 12 25,114,099 25,128,381 RGD:1600115
G Milr1 mast cell immunoglobulin-like receptor 1 JBrowse link 10 94,944,243 94,961,795 RGD:1624291
RGD:1600115
G Mrgprx2 MAS related GPR family member X2 JBrowse link 1 103,743,746 103,760,945 RGD:1624291
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 JBrowse link 5 63,781,801 63,822,890 RGD:1624291
RGD:1600115
G Pla2g3 phospholipase A2, group III JBrowse link 14 83,724,828 83,730,614 RGD:1624291
G Rasgrp1 RAS guanyl releasing protein 1 JBrowse link 3 108,984,029 109,044,420 RGD:1624291
G Tac4 tachykinin precursor 4 JBrowse link 10 83,081,168 83,089,487 RGD:1600115
mast cell mediated immunity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Serpinb9 serpin family B member 9 JBrowse link 17 32,648,846 32,673,047 RGD:1624291
G Spon2 spondin 2 JBrowse link 14 82,815,158 82,824,529 RGD:1624291
myeloid dendritic cell cytokine production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Camk4 calcium/calmodulin-dependent protein kinase IV JBrowse link 18 25,746,878 25,975,962 RGD:1624291
negative regulation of eosinophil degranulation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ccr2 C-C motif chemokine receptor 2 RGD:1624291
RGD:1600115
negative regulation of mast cell degranulation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd300a Cd300a molecule JBrowse link 10 103,437,978 103,451,170 RGD:1624291
G Cd84 CD84 molecule JBrowse link 13 90,241,369 90,283,625 RGD:1624291
G Foxf1 forkhead box F1 JBrowse link 19 53,012,306 53,016,100 RGD:1624291
G Hmox1 heme oxygenase 1 JBrowse link 19 14,508,634 14,515,455 RGD:1601626
G Il13ra2 interleukin 13 receptor subunit alpha 2 JBrowse link X 118,443,955 118,514,716 RGD:1624291
RGD:1600115
G Lgals9 galectin 9 JBrowse link 10 64,737,022 64,760,195 RGD:1624291
G Rabgef1 RAB guanine nucleotide exchange factor 1 JBrowse link 12 29,960,132 30,004,727 RGD:1624291
negative regulation of neutrophil degranulation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abr ABR activator of RhoGEF and GTPase JBrowse link 10 64,565,121 64,657,079 RGD:1624291
RGD:1600115
G Bcr BCR activator of RhoGEF and GTPase JBrowse link 20 14,421,250 14,546,406 RGD:1624291
neutrophil degranulation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Anxa3 annexin A3 JBrowse link 14 14,371,921 14,426,503 RGD:1624291
G Myo1f myosin IF JBrowse link 7 18,440,742 18,491,448 RGD:1624291
G Stx11 syntaxin 11 JBrowse link 1 7,039,160 7,064,870 RGD:1624291
G Stxbp2 syntaxin binding protein 2 JBrowse link 12 2,180,101 2,191,863 RGD:1600115
RGD:1624291
G Stxbp3 syntaxin binding protein 3 JBrowse link 2 211,595,763 211,638,756 RGD:1624291
G Vamp2 vesicle-associated membrane protein 2 JBrowse link 10 55,675,171 55,679,405 RGD:1624291
G Vamp7 vesicle-associated membrane protein 7 JBrowse link 12 18,996,566 19,033,714 RGD:8553828
RGD:1624291
G Vamp8 vesicle-associated membrane protein 8 JBrowse link 4 100,250,301 100,252,756 RGD:1624291
neutrophil mediated immunity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ace angiotensin I converting enzyme JBrowse link 10 94,170,766 94,213,831 RGD:1624291
RGD:1600115
G Cd300lb CD300 molecule-like family member b JBrowse link 10 103,471,082 103,481,071 RGD:1624291
G Fcar Fc fragment of IgA receptor JBrowse link 1 73,230,392 73,263,462 RGD:1624291
G Irak4 interleukin-1 receptor-associated kinase 4 JBrowse link 7 135,803,723 135,831,006 RGD:1624291
G Jagn1 jagunal homolog 1 JBrowse link 4 145,399,885 145,404,605 RGD:1624291
RGD:1600115
G Kmt2e lysine methyltransferase 2E JBrowse link 4 8,187,751 8,255,578 RGD:1624291
G Lyst lysosomal trafficking regulator JBrowse link 17 90,323,055 90,522,091 RGD:1624291
G Myo1f myosin IF JBrowse link 7 18,440,742 18,491,448 RGD:1624291
G Pla2g1b phospholipase A2 group IB JBrowse link 12 46,879,346 46,890,234 RGD:1624291
G Wdr1 WD repeat domain 1 JBrowse link 14 76,990,014 77,023,739 RGD:1624291
neutrophil-mediated killing of fungus term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Elane elastase, neutrophil expressed JBrowse link 7 12,638,320 12,640,168 RGD:1624291
G Ncf1 neutrophil cytosolic factor 1 JBrowse link 12 25,497,104 25,506,300 RGD:1624291
neutrophil-mediated killing of gram-negative bacterium term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Elane elastase, neutrophil expressed JBrowse link 7 12,638,320 12,640,168 RGD:1624291
G F2 coagulation factor II JBrowse link 3 80,529,468 80,542,993 RGD:1600115
RGD:1624291
G Trem1 triggering receptor expressed on myeloid cells 1 JBrowse link 9 14,727,887 14,743,371 RGD:1624291
G Trem3 triggering receptor expressed on myeloid cells 3 JBrowse link 9 14,713,935 14,725,945 RGD:1600115
G Tusc2 tumor suppressor 2, mitochondrial calcium regulator JBrowse link 8 116,318,963 116,322,181 RGD:1624291
neutrophil-mediated killing of gram-positive bacterium term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ctsg cathepsin G JBrowse link 15 35,107,333 35,113,678 RGD:1624291
RGD:1600115
G Ncf1 neutrophil cytosolic factor 1 JBrowse link 12 25,497,104 25,506,300 RGD:1624291
positive regulation of antibody-dependent cellular cytotoxicity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G RT1-S3 RT1 class Ib, locus S3 JBrowse link 20 3,176,124 3,180,825 RGD:1624291
positive regulation of eosinophil degranulation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G F2rl1 F2R like trypsin receptor 1 JBrowse link 2 25,222,324 25,235,275 RGD:1624291
G Stx4 syntaxin 4 JBrowse link 1 199,287,384 199,295,606 RGD:1600115
RGD:1624291
positive regulation of histamine secretion by mast cell term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nppa natriuretic peptide A JBrowse link 5 164,808,407 164,809,716 RGD:13461752
G Snx4 sorting nexin 4 JBrowse link 11 70,693,381 70,753,620 RGD:1624291
G Vamp7 vesicle-associated membrane protein 7 JBrowse link 12 18,996,566 19,033,714 RGD:1624291
G Vamp8 vesicle-associated membrane protein 8 JBrowse link 4 100,250,301 100,252,756 RGD:1600115
RGD:1624291
positive regulation of mast cell degranulation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adora2b adenosine A2B receptor JBrowse link 10 48,569,563 48,586,366 RGD:1624291
RGD:1600115
G Adora3 adenosine A3 receptor JBrowse link 2 208,336,909 208,379,217 RGD:1624291
G Crhr1 corticotropin releasing hormone receptor 1 JBrowse link 10 92,191,473 92,233,662 RGD:5130941
G Fcer1a Fc fragment of IgE receptor Ia JBrowse link 13 91,727,253 91,737,106 RGD:1624291
G Fcer1g Fc fragment of IgE receptor Ig JBrowse link 13 89,601,894 89,606,326 RGD:1624291
G Fgr FGR proto-oncogene, Src family tyrosine kinase JBrowse link 5 151,172,189 151,199,746 RGD:1624291
RGD:1600115
G Gab2 GRB2-associated binding protein 2 JBrowse link 1 162,082,876 162,283,379 RGD:1624291
RGD:1600115
G Gata1 GATA binding protein 1 JBrowse link X 15,273,937 15,281,759 RGD:9587812
G Gata2 GATA binding protein 2 JBrowse link 4 120,129,028 120,142,490 RGD:9587812
G Il13 interleukin 13 JBrowse link 10 38,982,909 38,985,466 RGD:1624291
G Il4 interleukin 4 JBrowse link 10 38,963,979 38,969,531 RGD:1624291
RGD:13792537
G Il4r interleukin 4 receptor JBrowse link 1 196,942,343 196,967,221 RGD:1624291
G Ms4a2 membrane spanning 4-domains A2 JBrowse link 1 227,957,363 227,965,312 RGD:1578516
G Nppc natriuretic peptide C JBrowse link 9 93,731,436 93,735,636 RGD:13461752
G Pld2 phospholipase D2 JBrowse link 10 57,161,921 57,181,148 RGD:2299903
G Sphk2 sphingosine kinase 2 JBrowse link 1 101,692,972 101,700,604 RGD:1624291
G Stxbp1 syntaxin binding protein 1 JBrowse link 3 11,823,779 11,885,479 RGD:12904029
G Stxbp2 syntaxin binding protein 2 JBrowse link 12 2,180,101 2,191,863 RGD:12904029
G Syk spleen associated tyrosine kinase JBrowse link 17 12,614,311 12,669,568 RGD:2299903
RGD:13792537
RGD:1600115
RGD:1624291
positive regulation of microglial cell mediated cytotoxicity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Itgam integrin subunit alpha M JBrowse link 1 199,495,312 199,545,738 RGD:1624291
G Stap1 signal transducing adaptor family member 1 JBrowse link 14 23,575,400 23,604,984 RGD:1624291
G Tyrobp transmembrane immune signaling adaptor Tyrobp JBrowse link 1 88,875,370 88,879,305 RGD:1624291
RGD:13792537
positive regulation of myeloid dendritic cell cytokine production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ddx1 DEAD-box helicase 1 JBrowse link 6 38,422,892 38,453,762 RGD:1624291
G Ddx21 DExD-box helicase 21 JBrowse link 20 32,213,147 32,232,632 RGD:1624291
G Ddx58 DEXD/H-box helicase 58 JBrowse link 5 56,486,584 56,536,898 RGD:1624291
G Dhx36 DEAH-box helicase 36 JBrowse link 2 152,785,844 152,824,549 RGD:1624291
G Mavs mitochondrial antiviral signaling protein JBrowse link 3 123,776,147 123,790,572 RGD:1600115
RGD:1624291
G Ticam1 toll-like receptor adaptor molecule 1 JBrowse link 9 10,780,185 10,790,280 RGD:1624291
positive regulation of neutrophil degranulation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd177 CD177 molecule JBrowse link 1 82,964,683 82,987,306 RGD:1624291
RGD:13792537
G Itgam integrin subunit alpha M JBrowse link 1 199,495,312 199,545,738 RGD:1624291
G Itgb2 integrin subunit beta 2 JBrowse link 20 11,777,773 11,815,647 RGD:1624291
G LOC100909620 CD177 antigen-like JBrowse link 1 81,555,412 81,560,629 RGD:13792537
G LOC100909700 CD177 antigen-like JBrowse link 1 81,609,177 81,627,763 RGD:13792537
G LOC100910611 CD177 antigen-like JBrowse link 1 81,564,683 81,584,541 RGD:13792537
G LOC100910953 CD177 antigen-like JBrowse link 1 82,815,709 82,820,487 RGD:13792537
G LOC102553892 CD177 antigen-like JBrowse link 1 82,947,303 82,952,884 RGD:13792537
G Ptafr platelet-activating factor receptor JBrowse link 5 150,746,284 150,775,675 RGD:10041060
G RGD1564380 similar to BC049730 protein JBrowse link 1 82,830,153 82,902,864 RGD:13792537
G RGD1565655 similar to BC049730 protein JBrowse link 1 81,592,004 81,597,637 RGD:13792537
positive regulation of neutrophil mediated killing of fungus term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arg1 arginase 1 JBrowse link 1 21,525,421 21,537,872 RGD:1624291
G Cxcl1 C-X-C motif chemokine ligand 1 JBrowse link 14 18,743,678 18,745,457 RGD:1600115
RGD:1624291
G Pomc proopiomelanocortin JBrowse link 6 28,382,937 28,388,771 RGD:1624291
positive regulation of neutrophil mediated killing of gram-negative bacterium term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G F2rl1 F2R like trypsin receptor 1 JBrowse link 2 25,222,324 25,235,275 RGD:1624291
positive regulation of type IIa hypersensitivity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G C3 complement C3 JBrowse link 9 9,721,137 9,747,084 RGD:1624291
RGD:1600115
G Fcer1g Fc fragment of IgE receptor Ig JBrowse link 13 89,601,894 89,606,326 RGD:1624291
G Fcgr1a Fc fragment of IgG receptor Ia JBrowse link 2 198,430,536 198,439,453 RGD:1624291
G Fcgr2a Fc fragment of IgG receptor IIa JBrowse link 13 91,146,878 91,163,691 RGD:1624291
G Ighg1 immunoglobulin heavy constant gamma 1 JBrowse link 6 139,140,572 139,784,388 RGD:1624291
positive regulation of type III hypersensitivity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Btk Bruton tyrosine kinase JBrowse link X 105,360,922 105,390,580 RGD:11040701
G Fcer1g Fc fragment of IgE receptor Ig JBrowse link 13 89,601,894 89,606,326 RGD:1624291
G Fcgr1a Fc fragment of IgG receptor Ia JBrowse link 2 198,430,536 198,439,453 RGD:1624291
G Fcgr2a Fc fragment of IgG receptor IIa JBrowse link 13 91,146,878 91,163,691 RGD:1624291
regulation of antibody-dependent cellular cytotoxicity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fcgr2a Fc fragment of IgG receptor IIa JBrowse link 13 91,146,878 91,163,691 RGD:2293335
regulation of histamine secretion by mast cell term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Snx6 sorting nexin 6 JBrowse link 6 75,626,927 75,670,172 RGD:1624291
G Vamp2 vesicle-associated membrane protein 2 JBrowse link 10 55,675,171 55,679,405 RGD:1624291
G Vamp3 vesicle-associated membrane protein 3 JBrowse link 5 168,126,157 168,136,628 RGD:1624291
regulation of mast cell degranulation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fer FER tyrosine kinase JBrowse link 9 111,557,804 111,868,583 RGD:13792537
G Fes FES proto-oncogene, tyrosine kinase JBrowse link 1 142,174,648 142,183,884 RGD:1624291
RGD:13792537
G Lyn LYN proto-oncogene, Src family tyrosine kinase JBrowse link 5 16,526,058 16,642,648 RGD:1624291
RGD:13792537
RGD:1600115
G Pdpk1 3-phosphoinositide dependent protein kinase-1 JBrowse link 10 13,446,373 13,525,248 RGD:1624291
G Rac2 Rac family small GTPase 2 JBrowse link 7 119,769,708 119,797,111 RGD:1624291
G RGD1311164 similar to DNA segment, Chr 6, Wayne State University 163, expressed JBrowse link 4 159,483,089 159,518,387 RGD:10047193
RGD:13792537
G Stxbp2 syntaxin binding protein 2 JBrowse link 12 2,180,101 2,191,863 RGD:2312429
G Unc13d unc-13 homolog D JBrowse link 10 104,613,907 104,628,664 RGD:1600115
RGD:1624291
regulation of neutrophil degranulation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pram1 PML-RARA regulated adaptor molecule 1 JBrowse link 7 18,507,878 18,516,321 RGD:1624291
G Syk spleen associated tyrosine kinase JBrowse link 17 12,614,311 12,669,568 RGD:1600115
RGD:1624291
regulation of neutrophil mediated cytotoxicity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dnase1 deoxyribonuclease 1 JBrowse link 10 11,757,681 11,760,672 RGD:1624291
RGD:13464261
G Dnase1l3 deoxyribonuclease 1-like 3 JBrowse link 15 18,710,492 18,736,476 RGD:1624291
RGD:13464261
regulation of neutrophil mediated killing of gram-negative bacterium term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cxcl6 C-X-C motif chemokine ligand 6 JBrowse link 14 18,860,201 18,920,839 RGD:1624291
serotonin secretion by mast cell term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd300a Cd300a molecule JBrowse link 10 103,437,978 103,451,170 RGD:1624291

Term paths to the root
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Term Annotations click to browse term
  biological_process 19578
    immune system process 2693
      immune effector process 861
        leukocyte mediated immunity 502
          myeloid leukocyte mediated immunity 117
            basophil mediated immunity + 1
            eosinophil mediated immunity + 7
            mast cell mediated immunity + 58
            microglial cell mediated cytotoxicity + 3
            myeloid dendritic cell cytokine production + 7
            negative regulation of myeloid leukocyte mediated immunity + 10
            neutrophil mediated immunity + 46
            positive regulation of myeloid leukocyte mediated immunity + 53
            regulation of myeloid leukocyte mediated immunity + 77
            type II hypersensitivity + 6
            type III hypersensitivity + 4
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.