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ONTOLOGY REPORT - ANNOTATIONS


Term:T cell mediated immunity
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Accession:GO:0002456 term browser browse the term
Definition:Any process involved in the carrying out of an immune response by a T cell.
Synonyms:exact_synonym: T lymphocyte mediated immunity
 broad_synonym: cell-mediated immunity;   cellular immune response


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T cell mediated immunity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd46 CD46 molecule JBrowse link 13 113,786,525 113,818,741 RGD:1624291
G Cd70 Cd70 molecule JBrowse link 9 9,842,585 9,845,728 RGD:1624291
G Cd8a CD8a molecule JBrowse link 4 99,217,640 99,243,352 RGD:1624291
RGD:13792537
G Cdh17 cadherin 17 JBrowse link 5 25,354,187 25,443,675 RGD:1624291
G Ephb6 Eph receptor B6 JBrowse link 4 70,903,253 70,918,514 RGD:1624291
G Foxp3 forkhead box P3 JBrowse link X 15,753,175 15,768,648 RGD:1624291
G Jag1 jagged canonical Notch ligand 1 JBrowse link 3 130,079,361 130,114,781 RGD:1600115
RGD:1624291
G Lyst lysosomal trafficking regulator JBrowse link 17 90,323,055 90,522,091 RGD:1624291
G Myo1g myosin IG JBrowse link 14 86,781,243 86,796,393 RGD:1624291
G Ntn1 netrin 1 JBrowse link 10 54,761,925 54,982,072 RGD:1600115
CD4-positive, alpha-beta T cell cytokine production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd55 CD55 molecule (Cromer blood group) JBrowse link 13 47,125,156 47,153,557 RGD:1624291
cytotoxic T cell degranulation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Rab27a RAB27A, member RAS oncogene family JBrowse link 8 79,722,334 79,776,228 RGD:1624291
G Stx11 syntaxin 11 JBrowse link 1 7,039,160 7,064,870 RGD:1624291
negative regulation of cytotoxic T cell degranulation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ceacam1 CEA cell adhesion molecule 1 JBrowse link 1 82,327,955 82,344,345 RGD:1624291
RGD:1600115
negative regulation of T cell antigen processing and presentation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hfe homeostatic iron regulator JBrowse link 17 43,661,276 43,669,327 RGD:1600115
negative regulation of T cell cytokine production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Foxp3 forkhead box P3 JBrowse link X 15,753,175 15,768,648 RGD:1624291
G Hfe homeostatic iron regulator JBrowse link 17 43,661,276 43,669,327 RGD:1624291
G RT1-CE5 RT1 class I, locus CE5 JBrowse link 20 4,892,702 4,896,993 RGD:1624291
G Slamf1 signaling lymphocytic activation molecule family member 1 JBrowse link 13 90,184,545 90,219,170 RGD:1624291
G Smad7 SMAD family member 7 JBrowse link 18 71,395,830 71,424,164 RGD:1600115
RGD:1624291
G Vsir V-set immunoregulatory receptor JBrowse link 20 29,897,543 29,923,381 RGD:1624291
G Xcl1 X-C motif chemokine ligand 1 JBrowse link 13 83,199,402 83,202,845 RGD:1624291
negative regulation of T cell mediated cytotoxicity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ceacam1 CEA cell adhesion molecule 1 JBrowse link 1 82,327,955 82,344,345 RGD:1624291
RGD:1600115
G Il7r interleukin 7 receptor RGD:1624291
G Ppp3cb protein phosphatase 3 catalytic subunit beta JBrowse link 15 4,209,702 4,236,895 RGD:1624291
RGD:1600115
G Ptprc protein tyrosine phosphatase, receptor type, C JBrowse link 13 55,061,561 55,174,150 RGD:1624291
RGD:1600115
negative regulation of T cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Muc4 mucin 4, cell surface associated JBrowse link 11 71,242,973 71,285,217 RGD:2303754
negative regulation of T cell mediated immunity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Clec4g C-type lectin domain family 4, member G JBrowse link 12 2,273,649 2,278,594 RGD:1624291
G Dusp22 dual specificity phosphatase 22 JBrowse link 17 34,986,589 35,037,297 RGD:1624291
G Nod2 nucleotide-binding oligomerization domain containing 2 JBrowse link 19 19,342,061 19,389,366 RGD:1624291
negative regulation of T-helper 2 cell cytokine production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arg1 arginase 1 JBrowse link 1 21,525,421 21,537,872 RGD:1624291
G Ifnb1 interferon beta 1 JBrowse link 5 106,865,192 106,865,746 RGD:1624291
G Tbx21 T-box transcription factor 21 JBrowse link 10 85,032,799 85,049,331 RGD:1624291
negative regulation of type IV hypersensitivity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Il20rb interleukin 20 receptor subunit beta JBrowse link 8 108,745,906 108,778,561 RGD:1624291
G Spn sialophorin JBrowse link 1 198,572,999 198,585,664 RGD:1624291
peripheral T cell tolerance induction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aire autoimmune regulator JBrowse link 20 11,365,630 11,380,636 RGD:1624291
RGD:13792537
positive regulation of peripheral T cell tolerance induction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Foxp3 forkhead box P3 JBrowse link X 15,753,175 15,768,648 RGD:1624291
positive regulation of T cell cytokine production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G B2m beta-2 microglobulin JBrowse link 3 114,087,287 114,093,311 RGD:1624291
G Fzd5 frizzled class receptor 5 JBrowse link 9 71,443,784 71,445,541 RGD:1624291
RGD:1600115
G LOC100364500 RT1 class I, locus CE11-like JBrowse link 20 2,704,153 2,707,111 RGD:1624291
G Malt1 MALT1 paracaspase JBrowse link 18 61,108,712 61,162,446 RGD:1624291
G Map3k7 mitogen activated protein kinase kinase kinase 7 JBrowse link 5 47,183,142 47,244,424 RGD:1624291
G Sash3 SAM and SH3 domain containing 3 JBrowse link X 134,979,637 134,994,351 RGD:1624291
G Tnfsf4 TNF superfamily member 4 JBrowse link 13 79,269,973 79,293,775 RGD:1624291
G Traf2 Tnf receptor-associated factor 2 JBrowse link 3 2,746,061 2,770,690 RGD:1624291
G Traf6 TNF receptor associated factor 6 JBrowse link 3 91,252,829 91,271,607 RGD:1624291
G Xcl1 X-C motif chemokine ligand 1 JBrowse link 13 83,199,402 83,202,845 RGD:1624291
positive regulation of T cell mediated cytotoxicity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AABR07044397.1 RGD:13792537
G AABR07044404.1 RGD:13792537
G Azgp1 alpha-2-glycoprotein 1, zinc-binding JBrowse link 12 19,196,565 19,203,094 RGD:13792537
G B2m beta-2 microglobulin JBrowse link 3 114,087,287 114,093,311 RGD:1624291
G Cd1d1 CD1d1 molecule JBrowse link 2 186,330,298 186,333,805 RGD:1624291
RGD:13792537
G Cyrib CYFIP related Rac1 interactor B JBrowse link 7 104,514,566 104,641,875 RGD:1624291
RGD:1600115
G Fadd Fas associated via death domain JBrowse link 1 217,746,176 217,748,581 RGD:1624291
RGD:1600115
G Fcgrt Fc fragment of IgG receptor and transporter JBrowse link 1 101,086,872 101,096,159 RGD:13792537
G Hfe homeostatic iron regulator JBrowse link 17 43,661,276 43,669,327 RGD:13792537
G Hspa1b heat shock protein family A (Hsp70) member 1B JBrowse link 20 4,877,638 4,880,112 RGD:1298959
G Hspa8 heat shock protein family A (Hsp70) member 8 JBrowse link 8 44,989,401 44,993,261 RGD:10059395
G Il12a interleukin 12A JBrowse link 2 165,076,945 165,083,996 RGD:1624291
RGD:1600115
G Il12b interleukin 12B JBrowse link 10 30,034,447 30,048,774 RGD:1624291
G Il23a interleukin 23 subunit alpha JBrowse link 7 2,710,609 2,712,723 RGD:1624291
G LOC100364500 RT1 class I, locus CE11-like JBrowse link 20 2,704,153 2,707,111 RGD:1624291
G LOC100909797 RT1 class I histocompatibility antigen, AA alpha chain-like JBrowse link 20 3,242,236 3,253,995 RGD:1624291
G Micb MHC class I polypeptide-related sequence B JBrowse link 1 79,754,587 79,772,092 RGD:13792537
G Mill1 MHC I like leukocyte 1 JBrowse link 1 79,631,266 79,657,943 RGD:13792537
G P2rx7 purinergic receptor P2X 7 JBrowse link 12 39,353,613 39,396,042 RGD:1624291
G Ptprc protein tyrosine phosphatase, receptor type, C JBrowse link 13 55,061,561 55,174,150 RGD:1624291
G RT1-A1 RT1 class Ia, locus A1 JBrowse link 20 5,414,463 5,418,012 RGD:2313503
RGD:13792537
G RT1-A2 RT1 class Ia, locus A2 JBrowse link 20 5,374,990 5,378,536 RGD:1624291
RGD:13792537
G RT1-CE10 RT1 class I, locus CE10 JBrowse link 20 129,192 157,689 RGD:13792537
G RT1-CE3 RT1 class I, locus CE3 JBrowse link 20 4,918,047 4,943,603 RGD:13792537
G RT1-CE4 RT1 class I, locus CE4 JBrowse link 20 4,918,523 4,921,339 RGD:13792537
G RT1-CE5 RT1 class I, locus CE5 JBrowse link 20 4,892,702 4,896,993 RGD:1624291
RGD:13792537
G RT1-EC2 RT1 class Ib, locus EC2 RGD:13792537
G RT1-M2 RT1 class Ib, locus M2 JBrowse link 20 1,337,242 1,339,488 RGD:13792537
G RT1-M3-1 RT1 class Ib, locus M3, gene 1 JBrowse link 20 1,814,661 1,833,033 RGD:13792537
G RT1-M4 RT1 class Ib, locus M4 JBrowse link 20 2,043,710 2,048,575 RGD:13792537
G RT1-M5 RT1 class Ib, locus M5 JBrowse link 20 2,038,158 2,040,422 RGD:13792537
G RT1-M6-2 RT1 class I, locus M6, gene 2 JBrowse link 20 2,075,796 2,079,183 RGD:13792537
G RT1-N2 RT1 class Ib, locus N2 JBrowse link 20 3,146,579 3,150,852 RGD:13792537
G RT1-N3 RT1 class Ib, locus N3 JBrowse link 20 3,166,793 3,170,945 RGD:13792537
G RT1-S2 RT1 class Ib, locus S2 JBrowse link 20 3,152,073 3,165,871 RGD:13792537
G RT1-S3 RT1 class Ib, locus S3 JBrowse link 20 3,176,124 3,180,825 RGD:1624291
RGD:13792537
G RT1-T24-1 RT1 class I, locus T24, gene 1 JBrowse link 20 3,269,315 3,282,523 RGD:13792537
G RT1-T24-3 RT1 class I, locus T24, gene 3 JBrowse link 20 3,226,010 3,257,254 RGD:13792537
G RT1-T24-4 RT1 class I, locus T24, gene 4 JBrowse link 20 3,189,457 3,197,457 RGD:13792537
G Stx7 syntaxin 7 JBrowse link 1 22,241,655 22,281,850 RGD:1624291
G Tap2 transporter 2, ATP binding cassette subfamily B member JBrowse link 20 3,995,544 4,009,587 RGD:1299069
RGD:1624291
G Xcl1 X-C motif chemokine ligand 1 JBrowse link 13 83,199,402 83,202,845 RGD:1624291
positive regulation of T cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mr1 major histocompatibility complex, class I-related JBrowse link 13 72,771,992 72,789,861 RGD:1624291
G Slc22a13 solute carrier family 22 member 13 JBrowse link 8 127,885,268 127,900,829 RGD:1624291
positive regulation of T cell mediated immune response to tumor cell term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd24 CD24 molecule JBrowse link 20 48,335,540 48,340,847 RGD:1624291
G Fbxo38 F-box protein 38 JBrowse link 18 57,827,391 57,874,515 RGD:1624291
G Hspd1 heat shock protein family D (Hsp60) member 1 JBrowse link 9 61,680,529 61,691,202 RGD:1624291
positive regulation of T cell mediated immunity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ptprc protein tyrosine phosphatase, receptor type, C JBrowse link 13 55,061,561 55,174,150 RGD:1624291
G Zbtb1 zinc finger and BTB domain containing 1 JBrowse link 6 99,401,775 99,425,739 RGD:1624291
positive regulation of T-helper 1 cell cytokine production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arid5a AT-rich interaction domain 5A JBrowse link 9 42,871,907 42,886,725 RGD:1624291
G Il18 interleukin 18 JBrowse link 8 55,009,666 55,016,286 RGD:1600115
RGD:1624291
G Il18r1 interleukin 18 receptor 1 JBrowse link 9 47,184,404 47,217,403 RGD:1624291
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:1600115
RGD:1624291
G Il1r1 interleukin 1 receptor type 1 JBrowse link 9 46,962,291 47,038,139 RGD:1600115
RGD:1624291
G Xcl1 X-C motif chemokine ligand 1 JBrowse link 13 83,199,402 83,202,845 RGD:1624291
RGD:1600115
positive regulation of T-helper 2 cell cytokine production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd81 Cd81 molecule JBrowse link 1 216,237,663 216,253,460 RGD:1600115
RGD:1624291
G Gata3 GATA binding protein 3 JBrowse link 17 72,419,752 72,452,043 RGD:1624291
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:1624291
G Nlrp3 NLR family, pyrin domain containing 3 JBrowse link 10 45,884,324 45,918,290 RGD:1624291
G Prkcz protein kinase C, zeta JBrowse link 5 172,658,071 172,769,492 RGD:1624291
RGD:1600115
G Rsad2 radical S-adenosyl methionine domain containing 2 JBrowse link 6 45,655,947 45,669,083 RGD:1600115
RGD:1624291
G Xcl1 X-C motif chemokine ligand 1 JBrowse link 13 83,199,402 83,202,845 RGD:1624291
RGD:1600115
positive regulation of type IV hypersensitivity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Zp3 zona pellucida glycoprotein 3 JBrowse link 12 23,735,225 23,752,734 RGD:1600115
RGD:1624291
regulation of T cell antigen processing and presentation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Was WASP actin nucleation promoting factor JBrowse link X 15,155,246 15,164,099 RGD:1624291
regulation of T cell cytokine production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ccl20 C-C motif chemokine ligand 20 JBrowse link 9 88,918,359 88,921,017 RGD:1624291
G Ccr2 C-C motif chemokine receptor 2 RGD:1600115
RGD:1624291
G Tnfrsf1b TNF receptor superfamily member 1B JBrowse link 5 163,136,390 163,167,299 RGD:1624291
RGD:13792537
G Trpm4 transient receptor potential cation channel, subfamily M, member 4 JBrowse link 1 101,293,300 101,323,484 RGD:1600115
RGD:1624291
regulation of T cell mediated cytotoxicity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ager advanced glycosylation end product-specific receptor JBrowse link 20 4,363,152 4,366,079 RGD:1600115
RGD:1624291
G Ripk3 receptor-interacting serine-threonine kinase 3 JBrowse link 15 34,470,796 34,479,741 RGD:1624291
RGD:1600115
regulation of T cell mediated immune response to tumor cell term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hmgb1 high mobility group box 1 JBrowse link 12 7,082,529 7,090,246 RGD:1624291
RGD:1600115
regulation of T cell mediated immunity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dpp4 dipeptidylpeptidase 4 JBrowse link 3 48,291,055 48,372,672 RGD:1626458
regulation of type IV hypersensitivity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fut7 fucosyltransferase 7 JBrowse link 3 2,637,281 2,646,497 RGD:1624291
susceptibility to T cell mediated cytotoxicity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nectin2 nectin cell adhesion molecule 2 JBrowse link 1 80,631,449 80,666,617 RGD:1624291
RGD:13792537
G Pvr PVR cell adhesion molecule JBrowse link 1 80,820,306 80,835,712 RGD:1624291
RGD:13792537
T cell antigen processing and presentation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Icam1 intercellular adhesion molecule 1 JBrowse link 8 22,035,287 22,047,049 RGD:1624291
G Kdm5d lysine demethylase 5D JBrowse link Y 501,058 589,267 RGD:1624291
G Rftn1 raftlin lipid raft linker 1 JBrowse link 9 12,740,885 12,942,358 RGD:1624291
G Treml4 triggering receptor expressed on myeloid cells-like 4 JBrowse link 9 14,668,691 14,707,122 RGD:1624291
G Trex1 three prime repair exonuclease 1 JBrowse link 8 117,796,127 117,797,427 RGD:1624291
T cell cytokine production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dlg1 discs large MAGUK scaffold protein 1 JBrowse link 11 72,164,566 72,378,895 RGD:1624291
RGD:1600115
G Kdelr1 KDEL endoplasmic reticulum protein retention receptor 1 JBrowse link 1 101,859,346 101,870,232 RGD:1624291
G Slc11a1 solute carrier family 11 member 1 JBrowse link 9 81,655,590 81,666,697 RGD:1624291
RGD:1600115
T cell mediated cytotoxicity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cadm1 cell adhesion molecule 1 JBrowse link 8 51,858,906 52,200,591 RGD:1624291
G Crtam cytotoxic and regulatory T cell molecule JBrowse link 8 45,152,584 45,216,082 RGD:1624291
G Ctsc cathepsin C JBrowse link 1 151,918,514 151,949,979 RGD:1624291
G Ctsh cathepsin H JBrowse link 8 97,439,155 97,458,293 RGD:1624291
RGD:1600115
G Emp2 epithelial membrane protein 2 JBrowse link 10 5,433,248 5,467,840 RGD:1624291
RGD:1600115
G Gzmb granzyme B JBrowse link 15 35,413,862 35,417,293 RGD:1624291
G Gzmm granzyme M JBrowse link 7 12,893,431 12,899,004 RGD:1624291
RGD:1600115
G Hprt1 hypoxanthine phosphoribosyltransferase 1 JBrowse link X 158,196,640 158,228,815 RGD:1624291
G LOC100364500 RT1 class I, locus CE11-like JBrowse link 20 2,704,153 2,707,111 RGD:1624291
G Prf1 perforin 1 JBrowse link 20 30,915,294 30,920,804 RGD:1624291
RGD:1600115
G Raet1e retinoic acid early transcript 1E JBrowse link 1 1,101,666 1,120,340 RGD:1624291
G Serpinb9 serpin family B member 9 JBrowse link 17 32,648,846 32,673,047 RGD:1624291
G Spag6l sperm associated antigen 6-like JBrowse link 11 88,424,493 88,517,910 RGD:1600115
G Stx11 syntaxin 11 JBrowse link 1 7,039,160 7,064,870 RGD:1624291
G Tsta3 tissue specific transplantation antigen P35B JBrowse link 7 116,958,427 116,963,281 RGD:1624291
T cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G LOC100364500 RT1 class I, locus CE11-like JBrowse link 20 2,704,153 2,707,111 RGD:1624291
T-helper 1 cell cytokine production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Il12a interleukin 12A JBrowse link 2 165,076,945 165,083,996 RGD:1624291
RGD:1600115
G Il12b interleukin 12B JBrowse link 10 30,034,447 30,048,774 RGD:1624291
G Il18 interleukin 18 JBrowse link 8 55,009,666 55,016,286 RGD:1624291
RGD:1600115
G Il18rap interleukin 18 receptor accessory protein JBrowse link 9 47,225,543 47,255,805 RGD:1624291
G Slamf1 signaling lymphocytic activation molecule family member 1 JBrowse link 13 90,184,545 90,219,170 RGD:1624291
T-helper 2 cell cytokine production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Crlf2 cytokine receptor-like factor 2 JBrowse link 14 1,456,843 1,461,543 RGD:1624291
G Dennd1b DENN domain containing 1B JBrowse link 13 56,015,813 56,242,041 RGD:1624291
RGD:13792537
G Gba glucosylceramidase beta JBrowse link 2 188,511,781 188,522,602 RGD:1624291
G Il31ra interleukin 31 receptor A JBrowse link 2 44,333,347 44,408,005 RGD:1624291
G Il4 interleukin 4 JBrowse link 10 38,963,979 38,969,531 RGD:1624291
RGD:13792537
G Stard7 StAR-related lipid transfer domain containing 7 JBrowse link 3 119,698,655 119,727,303 RGD:1624291
type IV hypersensitivity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ephb6 Eph receptor B6 JBrowse link 4 70,903,253 70,918,514 RGD:1624291
G Gata3 GATA binding protein 3 JBrowse link 17 72,419,752 72,452,043 RGD:2314191

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19575
    immune system process 2692
      immune effector process 860
        leukocyte mediated immunity 501
          lymphocyte mediated immunity 397
            T cell mediated immunity 136
              T cell antigen processing and presentation + 7
              T cell cytokine production + 47
              T cell mediated cytotoxicity + 67
              T cell mediated immune response to tumor cell + 8
              negative regulation of T cell mediated immunity + 20
              peripheral T cell tolerance induction + 2
              positive regulation of T cell mediated immunity + 70
              regulation of T cell mediated immunity + 95
              type IV hypersensitivity + 6
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.