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ONTOLOGY REPORT - ANNOTATIONS


Term:adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
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Accession:GO:0002460 term browser browse the term
Definition:An immune response mediated by lymphocytes expressing specific receptors for antigen produced through a somatic diversification process that includes somatic recombination of germline gene segments encoding immunoglobulin superfamily domains. Recombined receptors for antigen encoded by immunoglobulin superfamily domains include T cell receptors and immunoglobulins (antibodies) produced by B cells. The first encounter with antigen elicits a primary immune response that is slow and not of great magnitude. T and B cells selected by antigen become activated and undergo clonal expansion. A fraction of antigen-reactive T and B cells become memory cells, whereas others differentiate into effector cells. The memory cells generated during the primary response enable a much faster and stronger secondary immune response upon subsequent exposures to the same antigen (immunological memory). An example of this is the adaptive immune response found in Mus musculus.


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adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:1624291
antibody-dependent cellular cytotoxicity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fcgr1a Fc fragment of IgG receptor Ia JBrowse link 2 198,430,536 198,439,453 RGD:1624291
G Fcgr2a Fc fragment of IgG receptor IIa JBrowse link 13 91,146,878 91,163,691 RGD:1624291
G Ighg1 immunoglobulin heavy constant gamma 1 JBrowse link 6 139,140,572 139,784,388 RGD:1624291
B cell affinity maturation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Btk Bruton tyrosine kinase JBrowse link X 105,360,922 105,390,580 RGD:1624291
G RT1-Bb RT1 class II, locus Bb JBrowse link 20 4,043,726 4,049,367 RGD:1624291
RGD:1600115
B cell cytokine production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hspd1 heat shock protein family D (Hsp60) member 1 JBrowse link 9 61,680,529 61,691,202 RGD:1624291
B cell mediated immunity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd19 CD19 molecule JBrowse link 1 197,815,422 197,822,123 RGD:1624291
G Cd70 Cd70 molecule JBrowse link 9 9,842,585 9,845,728 RGD:1624291
G Fas Fas cell surface death receptor JBrowse link 1 252,589,785 252,624,790 RGD:1624291
G Msh2 mutS homolog 2 JBrowse link 6 11,215,951 11,274,916 RGD:1624291
G Ntn1 netrin 1 JBrowse link 10 54,761,925 54,982,072 RGD:1600115
G Pirb paired Ig-like receptor B JBrowse link 1 64,074,097 64,081,568 RGD:1624291
CD4-positive, alpha-beta T cell cytokine production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd55 CD55 molecule (Cromer blood group) JBrowse link 13 47,125,156 47,153,557 RGD:1624291
complement activation, classical pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AABR07034739.1 Ig lambda-2 chain C region RGD:13792537
G AABR07065640.1 RGD:13792537
G AABR07065643.1 RGD:13792537
G AABR07065645.1 RGD:13792537
G AABR07065645.2 RGD:13792537
G AABR07065651.2 RGD:13792537
G AABR07065651.3 RGD:13792537
G AABR07065651.4 RGD:13792537
G AABR07065651.5 RGD:13792537
G AABR07065651.6 RGD:13792537
G AABR07065651.7 RGD:13792537
G AABR07065651.8 RGD:13792537
G AABR07065656.1 RGD:13792537
G AABR07065656.10 RGD:13792537
G AABR07065656.2 RGD:13792537
G AABR07065656.3 RGD:13792537
G AABR07065656.4 RGD:13792537
G AABR07065656.5 RGD:13792537
G AABR07065656.6 RGD:13792537
G AABR07065656.7 RGD:13792537
G AABR07065656.9 RGD:13792537
G AABR07065673.1 RGD:13792537
G AABR07065676.1 RGD:13792537
G AABR07065680.1 RGD:13792537
G AABR07065688.1 RGD:13792537
G AABR07065693.1 RGD:13792537
G AABR07065693.2 RGD:13792537
G AABR07065693.3 RGD:13792537
G AABR07065699.2 RGD:13792537
G AABR07065699.3 RGD:13792537
G AABR07065699.4 RGD:13792537
G AABR07065699.5 RGD:13792537
G AABR07065705.4 RGD:13792537
G AABR07065705.5 RGD:13792537
G AABR07065705.6 RGD:13792537
G AABR07065714.1 RGD:13792537
G AABR07065737.1 RGD:13792537
G AABR07065740.1 RGD:13792537
G AABR07065750.1 RGD:13792537
G AABR07065750.2 RGD:13792537
G AABR07065753.1 RGD:13792537
G AABR07065768.1 RGD:13792537
G AABR07065768.2 RGD:13792537
G AABR07065768.3 RGD:13792537
G AABR07065772.1 RGD:13792537
G AABR07065772.2 RGD:13792537
G AABR07065772.4 RGD:13792537
G AABR07065773.1 RGD:13792537
G AABR07065774.1 RGD:13792537
G AABR07065776.2 RGD:13792537
G AABR07065778.1 RGD:13792537
G AABR07065778.2 RGD:13792537
G AABR07065778.3 RGD:13792537
G AABR07065782.1 RGD:13792537
G AABR07065789.1 RGD:13792537
G AABR07065789.2 RGD:13792537
G AABR07065789.3 RGD:13792537
G AABR07065790.1 RGD:13792537
G AABR07065792.1 RGD:13792537
G AABR07065792.2 RGD:13792537
G AABR07065798.1 RGD:13792537
G AABR07065802.1 RGD:13792537
G AABR07065804.1 RGD:13792537
G AABR07065808.1 RGD:13792537
G AABR07065811.1 RGD:13792537
G AABR07065812.1 RGD:13792537
G AABR07065812.2 RGD:13792537
G AABR07065813.1 RGD:13792537
G AABR07065814.1 RGD:13792537
G AABR07065814.2 RGD:13792537
G AABR07065814.3 RGD:13792537
G AABR07065814.4 RGD:13792537
G AABR07065814.5 RGD:13792537
G AABR07065814.7 RGD:13792537
G AABR07065815.1 RGD:13792537
G AABR07065815.2 RGD:13792537
G AABR07065821.1 RGD:13792537
G AABR07065823.2 RGD:13792537
G AABR07065823.3 RGD:13792537
G AABR07065827.1 RGD:13792537
G AABR07065834.1 RGD:13792537
G AABR07065837.1 RGD:13792537
G AABR07065839.1 RGD:13792537
G AABR07065844.1 RGD:13792537
G AABR07065883.1 RGD:13792537
G AABR07065886.1 RGD:13792537
G AABR07065889.1 RGD:13792537
G AC109737.1 RGD:13792537
G Apcs amyloid P component, serum JBrowse link 13 91,426,621 91,427,417 RGD:13792537
G C1qa complement C1q A chain JBrowse link 5 155,261,254 155,264,101 RGD:1624291
G C1qb complement C1q B chain JBrowse link 5 155,246,444 155,251,995 RGD:1600115
G C1qbp complement C1q binding protein JBrowse link 10 57,613,876 57,618,527 RGD:1600115
G C1qc complement C1q C chain JBrowse link 5 155,255,013 155,258,631 RGD:1600115
G C1r complement C1r JBrowse link 4 157,126,060 157,136,825 RGD:1600115
G C1rl complement C1r subcomponent like JBrowse link 4 157,108,190 157,122,689 RGD:1600115
G C1s complement C1s JBrowse link 4 157,143,592 157,155,592 RGD:1600115
G C2 complement C2 JBrowse link 20 4,542,340 4,561,152 RGD:1600115
G C3 complement C3 JBrowse link 9 9,721,137 9,747,084 RGD:1600605
G C4a complement C4A JBrowse link 20 2,651,599 2,678,183 RGD:1600115
G C4bpa complement component 4 binding protein, alpha JBrowse link 13 47,342,090 47,377,580 RGD:1600115
G C4bpb complement component 4 binding protein, beta JBrowse link 13 47,387,173 47,398,115 RGD:1600115
G C5 complement C5 JBrowse link 3
3
14,049,993
14,206,466
14,113,931
14,229,141
RGD:1600115
G C6 complement C6 JBrowse link 2 54,460,333 54,533,801 RGD:1600115
G C8b complement C8 beta chain JBrowse link 5 124,298,269 124,338,055 RGD:1600115
G C9 complement C9 JBrowse link 2 55,775,562 55,823,807 RGD:1600115
G Cfb complement factor B JBrowse link 20 4,536,206 4,542,073 RGD:1600115
G Cfi complement factor I JBrowse link 2 235,264,149 235,305,779 RGD:1600115
G Cr1l complement C3b/C4b receptor 1 like JBrowse link 13 113,824,886 113,872,097 RGD:1600115
G Crp C-reactive protein JBrowse link 13 91,080,448 91,081,358 RGD:1580273
RGD:13792537
G IgG-2a gamma-2a immunoglobulin heavy chain RGD:13792537
G Igh-6 immunoglobulin heavy chain 6 RGD:13792537
G Ighe immunoglobulin heavy constant epsilon JBrowse link 6 138,066,728 138,068,606 RGD:13792537
G Ighg1 immunoglobulin heavy constant gamma 1 JBrowse link 6 139,140,572 139,784,388 RGD:1624291
RGD:13792537
G Ighm immunoglobulin heavy constant mu RGD:13792537
G Igkc immunoglobulin kappa constant RGD:13792537
G Igll1 immunoglobulin lambda-like polypeptide 1 JBrowse link 11 88,388,378 88,391,524 RGD:13792537
G LOC100361706 lambda-chain C1-region-like JBrowse link 11 86,094,822 86,096,399 RGD:13792537
G LOC100911854 mannose-binding protein C-like JBrowse link 1 248,723,370 248,730,969 RGD:1600115
G LOC362795 immunoglobulin G heavy chain JBrowse link 6 138,192,156 138,201,560 RGD:13792537
G Masp2 mannan-binding lectin serine peptidase 2 JBrowse link 5 165,415,105 165,429,857 RGD:1600115
G Mbl1 mannose-binding lectin (protein A) 1 JBrowse link 16 18,736,154 18,742,193 RGD:1600115
G Mbl2 mannose binding lectin 2 JBrowse link 1 248,435,069 248,442,669 RGD:1600115
G Mptx1 mucosal pentraxin 1 JBrowse link 13 91,772,927 91,827,231 RGD:13792537
G RGD1564318 similar to immunoglobulin light chain variable region RGD:13792537
G Serping1 serpin family G member 1 JBrowse link 3 72,161,230 72,171,109 RGD:1600115
cytotoxic T cell degranulation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Rab27a RAB27A, member RAS oncogene family JBrowse link 8 79,722,334 79,776,228 RGD:1624291
G Stx11 syntaxin 11 JBrowse link 1 7,039,160 7,064,870 RGD:1624291
germinal center formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adam17 ADAM metallopeptidase domain 17 JBrowse link 6 43,400,525 43,448,280 RGD:1624291
G Bcl3 BCL3, transcription coactivator JBrowse link 1 80,730,758 80,745,273 RGD:1624291
G Bcl6 BCL6, transcription repressor JBrowse link 11 80,255,790 80,279,075 RGD:1624291
G Klhl6 kelch-like family member 6 JBrowse link 11 84,745,958 84,785,315 RGD:1624291
G Mef2c myocyte enhancer factor 2C JBrowse link 2 11,658,534 11,822,788 RGD:1600115
RGD:1624291
G Nfkb2 nuclear factor kappa B subunit 2 JBrowse link 1 266,050,634 266,059,277 RGD:1624291
G Spag6l sperm associated antigen 6-like JBrowse link 11 88,424,493 88,517,910 RGD:1600115
G Unc13d unc-13 homolog D JBrowse link 10 104,613,907 104,628,664 RGD:1624291
RGD:1600115
helper T cell enhancement of adaptive immune response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd4 Cd4 molecule JBrowse link 4 157,381,862 157,408,357 RGD:1624291
humoral immune response mediated by circulating immunoglobulin term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bcl3 BCL3, transcription coactivator JBrowse link 1 80,730,758 80,745,273 RGD:1624291
G Cd81 Cd81 molecule JBrowse link 1 216,237,663 216,253,460 RGD:1600115
RGD:1624291
G Exo1 exonuclease 1 JBrowse link 13 93,936,989 93,962,749 RGD:1624291
G Ighg1 immunoglobulin heavy constant gamma 1 JBrowse link 6 139,140,572 139,784,388 RGD:1624291
G RT1-Bb RT1 class II, locus Bb JBrowse link 20 4,043,726 4,049,367 RGD:1624291
G RT1-Db1 RT1 class II, locus Db1 JBrowse link 20 4,087,621 4,097,190 RGD:1624291
G Zp2 zona pellucida glycoprotein 2 JBrowse link 1 189,899,906 189,911,650 RGD:1624291
G Zp3 zona pellucida glycoprotein 3 JBrowse link 12 23,735,225 23,752,734 RGD:1600115
RGD:1624291
immune complex formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Trex1 three prime repair exonuclease 1 JBrowse link 8 117,796,127 117,797,427 RGD:1624291
immunoglobulin biosynthetic process involved in immune response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Trex1 three prime repair exonuclease 1 JBrowse link 8 117,796,127 117,797,427 RGD:1624291
immunoglobulin mediated immune response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bcl10 BCL10, immune signaling adaptor JBrowse link 2 251,805,392 251,814,957 RGD:1624291
G C4b complement C4B (Chido blood group) JBrowse link 20 4,302,344 4,316,752 RGD:1624291
G Cd19 CD19 molecule JBrowse link 1 197,815,422 197,822,123 RGD:1624291
G Cd74 CD74 molecule JBrowse link 18 56,071,420 56,080,851 RGD:1624291
G Cfh complement factor H JBrowse link 13 56,979,155 57,080,540 RGD:1624291
G Cr2 complement C3d receptor 2 JBrowse link 13 113,890,274 113,927,824 RGD:1624291
G Fcer1g Fc fragment of IgE receptor Ig JBrowse link 13 89,601,894 89,606,326 RGD:1624291
RGD:13792537
G Fcgr2b Fc fragment of IgG receptor IIb JBrowse link 13 89,329,298 89,343,916 RGD:1624291
G Ighg1 immunoglobulin heavy constant gamma 1 JBrowse link 6 139,140,572 139,784,388 RGD:1624291
G Il13ra2 interleukin 13 receptor subunit alpha 2 JBrowse link X 118,443,955 118,514,716 RGD:1624291
RGD:1600115
G Il4r interleukin 4 receptor JBrowse link 1 196,942,343 196,967,221 RGD:1624291
G Inpp5d inositol polyphosphate-5-phosphatase D JBrowse link 9 94,745,220 94,850,778 RGD:1624291
RGD:1600115
G Irf7 interferon regulatory factor 7 JBrowse link 1 214,249,388 214,252,909 RGD:1624291
G LOC100909593 class II histocompatibility antigen, M alpha chain-like JBrowse link 20 3,935,501 3,938,915 RGD:1624291
G Myd88 MYD88, innate immune signal transduction adaptor JBrowse link 8 128,022,512 128,027,462 RGD:1624291
G Prkcd protein kinase C, delta JBrowse link 16 6,655,131 6,675,746 RGD:1624291
RGD:1600115
G RT1-DMa RT1 class II, locus DMa JBrowse link 20 3,935,512 3,938,915 RGD:1624291
G Tcirg1 T-cell immune regulator 1, ATPase H+ transporting V0 subunit A3 JBrowse link 1 219,126,687 219,139,466 RGD:1624291
G Tlr4 toll-like receptor 4 JBrowse link 5 82,587,424 82,601,056 RGD:2312508
G Tnfsf13 TNF superfamily member 13 JBrowse link 10 56,286,964 56,290,680 RGD:1624291
immunoglobulin production in mucosal tissue term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gcnt3 glucosaminyl (N-acetyl) transferase 3, mucin type JBrowse link 8 76,449,078 76,459,431 RGD:1624291
G Tnfsf13 TNF superfamily member 13 JBrowse link 10 56,286,964 56,290,680 RGD:1624291
immunoglobulin production involved in immunoglobulin mediated immune response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fgl2 fibrinogen-like 2 JBrowse link 4 10,323,598 10,329,241 RGD:1624291
G Gapt Grb2-binding adaptor protein, transmembrane JBrowse link 2 41,869,555 41,874,130 RGD:1624291
RGD:13792537
G Nod2 nucleotide-binding oligomerization domain containing 2 JBrowse link 19 19,342,061 19,389,366 RGD:1624291
G RT1-Bb RT1 class II, locus Bb JBrowse link 20 4,043,726 4,049,367 RGD:1624291
G RT1-Db1 RT1 class II, locus Db1 JBrowse link 20 4,087,621 4,097,190 RGD:1624291
immunoglobulin secretion involved in immune response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Crlf2 cytokine receptor-like factor 2 JBrowse link 14 1,456,843 1,461,543 RGD:1624291
G Pou2f2 POU class 2 homeobox 2 JBrowse link 1 81,966,791 82,049,116 RGD:1624291
isotype switching term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aicda activation-induced cytidine deaminase JBrowse link 4 155,359,909 155,371,104 RGD:1624291
G Atad5 ATPase family, AAA domain containing 5 JBrowse link 10 67,427,042 67,475,825 RGD:1624291
G Batf basic leucine zipper ATF-like transcription factor JBrowse link 6 109,562,415 109,584,541 RGD:1600115
RGD:1624291
G Cd40lg CD40 ligand JBrowse link X 159,703,703 159,714,886 RGD:1600115
RGD:1624291
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit JBrowse link 1 80,256,973 80,268,198 RGD:1624291
G Exo1 exonuclease 1 JBrowse link 13 93,936,989 93,962,749 RGD:1624291
G Exosc3 exosome component 3 JBrowse link 5 60,866,498 60,871,734 RGD:1624291
G Exosc6 exosome component 6 JBrowse link 19 43,190,879 43,193,164 RGD:1624291
G Lig4 DNA ligase 4 JBrowse link 16 85,331,771 85,339,496 RGD:1624291
G Mlh1 mutL homolog 1 JBrowse link 8 119,486,655 119,523,716 RGD:1624291
RGD:1600115
G Msh2 mutS homolog 2 JBrowse link 6 11,215,951 11,274,916 RGD:1600115
RGD:1624291
G Msh6 mutS homolog 6 JBrowse link 6 11,644,565 11,662,389 RGD:1624291
G Nbn nibrin JBrowse link 5 29,622,347 29,656,877 RGD:1600115
RGD:1624291
G Rnf168 ring finger protein 168 JBrowse link 11 71,721,242 71,743,421 RGD:1624291
RGD:1600115
G Rnf8 ring finger protein 8 JBrowse link 20 8,285,380 8,309,858 RGD:1624291
RGD:1600115
G Swap70 switching B-cell complex subunit SWAP70 JBrowse link 1 174,862,683 174,924,101 RGD:1624291
G Ung uracil-DNA glycosylase JBrowse link 12 48,246,593 48,255,547 RGD:1624291
G Xrcc4 X-ray repair cross complementing 4 JBrowse link 2 18,674,496 18,927,463 RGD:1624291
isotype switching to IgA isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ccr6 C-C motif chemokine receptor 6 JBrowse link 1 53,063,380 53,087,519 RGD:1624291
isotype switching to IgG isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hspd1 heat shock protein family D (Hsp60) member 1 JBrowse link 9 61,680,529 61,691,202 RGD:1624291
negative regulation of complement activation, classical pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G C4bpa complement component 4 binding protein, alpha JBrowse link 13 47,342,090 47,377,580 RGD:1624291
RGD:1600115
G C4bpb complement component 4 binding protein, beta JBrowse link 13 47,387,173 47,398,115 RGD:1624291
RGD:1600115
G Cd46 CD46 molecule JBrowse link 13 113,786,525 113,818,741 RGD:1624291
G Susd4 sushi domain containing 4 JBrowse link 13 101,181,932 101,307,912 RGD:1624291
negative regulation of cytotoxic T cell degranulation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ceacam1 CEA cell adhesion molecule 1 JBrowse link 1 82,327,955 82,344,345 RGD:1624291
RGD:1600115
negative regulation of germinal center formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Foxj1 forkhead box J1 JBrowse link 10 105,282,090 105,289,396 RGD:1624291
G Rc3h1 ring finger and CCCH-type domains 1 JBrowse link 13 78,723,028 78,794,663 RGD:1624291
negative regulation of humoral immune response mediated by circulating immunoglobulin term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fcgr2b Fc fragment of IgG receptor IIb JBrowse link 13 89,329,298 89,343,916 RGD:1624291
G Foxj1 forkhead box J1 JBrowse link 10 105,282,090 105,289,396 RGD:1624291
G Ptpn6 protein tyrosine phosphatase, non-receptor type 6 JBrowse link 4 157,239,141 157,263,890 RGD:1624291
RGD:1600115
negative regulation of isotype switching term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Parp3 poly (ADP-ribose) polymerase family, member 3 JBrowse link 8 115,173,440 115,179,543 RGD:1624291
negative regulation of isotype switching to IgA isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Da2-19 uncharacterized LOC302729 JBrowse link X 48,196,789 48,213,506 RGD:1600115
G Thoc1 THO complex 1 JBrowse link 18 1,142,540 1,177,084 RGD:1624291
negative regulation of isotype switching to IgE isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bcl6 BCL6, transcription repressor JBrowse link 11 80,255,790 80,279,075 RGD:1624291
G Foxp3 forkhead box P3 JBrowse link X 15,753,175 15,768,648 RGD:1624291
G Ndfip1 Nedd4 family interacting protein 1 JBrowse link 18 31,574,759 31,625,286 RGD:1624291
negative regulation of T cell antigen processing and presentation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hfe homeostatic iron regulator JBrowse link 17 43,661,276 43,669,327 RGD:1600115
negative regulation of T cell cytokine production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Foxp3 forkhead box P3 JBrowse link X 15,753,175 15,768,648 RGD:1624291
G Hfe homeostatic iron regulator JBrowse link 17 43,661,276 43,669,327 RGD:1624291
G RT1-CE5 RT1 class I, locus CE5 JBrowse link 20 4,892,702 4,896,993 RGD:1624291
G Slamf1 signaling lymphocytic activation molecule family member 1 JBrowse link 13 90,184,545 90,219,170 RGD:1624291
G Smad7 SMAD family member 7 JBrowse link 18 71,395,830 71,424,164 RGD:1600115
RGD:1624291
G Vsir V-set immunoregulatory receptor JBrowse link 20 29,897,543 29,923,381 RGD:1624291
G Xcl1 X-C motif chemokine ligand 1 JBrowse link 13 83,199,402 83,202,845 RGD:1624291
negative regulation of T cell mediated cytotoxicity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ceacam1 CEA cell adhesion molecule 1 JBrowse link 1 82,327,955 82,344,345 RGD:1624291
RGD:1600115
G Il7r interleukin 7 receptor RGD:1624291
G Ppp3cb protein phosphatase 3 catalytic subunit beta JBrowse link 15 4,209,702 4,236,895 RGD:1624291
RGD:1600115
G Ptprc protein tyrosine phosphatase, receptor type, C JBrowse link 13 55,061,561 55,174,150 RGD:1624291
RGD:1600115
negative regulation of T cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Muc4 mucin 4, cell surface associated JBrowse link 11 71,242,973 71,285,217 RGD:2303754
negative regulation of T cell mediated immunity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Clec4g C-type lectin domain family 4, member G JBrowse link 12 2,273,649 2,278,594 RGD:1624291
G Dusp22 dual specificity phosphatase 22 JBrowse link 17 34,986,589 35,037,297 RGD:1624291
G Nod2 nucleotide-binding oligomerization domain containing 2 JBrowse link 19 19,342,061 19,389,366 RGD:1624291
negative regulation of T-helper 1 cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Il4r interleukin 4 receptor JBrowse link 1 196,942,343 196,967,221 RGD:1624291
G Jak3 Janus kinase 3 JBrowse link 16 20,107,471 20,120,678 RGD:1624291
RGD:1600115
G Tnfsf4 TNF superfamily member 4 JBrowse link 13 79,269,973 79,293,775 RGD:1624291
negative regulation of T-helper 1 type immune response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Havcr2 hepatitis A virus cellular receptor 2 JBrowse link 10 31,561,838 31,590,624 RGD:1624291
G Il1rl1 interleukin 1 receptor-like 1 JBrowse link 9 47,133,483 47,184,316 RGD:1624291
RGD:1600115
G Il33 interleukin 33 JBrowse link 1 248,112,611 248,147,030 RGD:1624291
RGD:1600115
negative regulation of T-helper 17 cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Foxp3 forkhead box P3 JBrowse link X 15,753,175 15,768,648 RGD:1624291
G Il2 interleukin 2 JBrowse link 2 123,847,150 123,851,854 RGD:1624291
G Il4 interleukin 4 JBrowse link 10 38,963,979 38,969,531 RGD:1624291
G Rc3h1 ring finger and CCCH-type domains 1 JBrowse link 13 78,723,028 78,794,663 RGD:1624291
G Rc3h2 ring finger and CCCH-type domains 2 JBrowse link 3 21,621,976 21,676,789 RGD:1624291
G Smad7 SMAD family member 7 JBrowse link 18 71,395,830 71,424,164 RGD:1600115
RGD:1624291
G Tbx21 T-box transcription factor 21 JBrowse link 10 85,032,799 85,049,331 RGD:1624291
G Zbtb7b zinc finger and BTB domain containing 7B JBrowse link 2 188,704,989 188,719,674 RGD:1624291
G Zc3h12a zinc finger CCCH type containing 12A JBrowse link 5 143,111,342 143,120,131 RGD:1600115
RGD:1624291
negative regulation of T-helper 17 cell lineage commitment term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Loxl3 lysyl oxidase-like 3 JBrowse link 4 113,866,782 113,883,713 RGD:1624291
G Tbx21 T-box transcription factor 21 JBrowse link 10 85,032,799 85,049,331 RGD:1624291
G Tnfsf18 TNF superfamily member 18 JBrowse link 13 79,378,412 79,388,687 RGD:1624291
negative regulation of T-helper 17 type immune response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Il27ra interleukin 27 receptor subunit alpha JBrowse link 19 25,151,835 25,163,995 RGD:1624291
G Smad7 SMAD family member 7 JBrowse link 18 71,395,830 71,424,164 RGD:1624291
negative regulation of T-helper 2 cell cytokine production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arg1 arginase 1 JBrowse link 1 21,525,421 21,537,872 RGD:1624291
G Ifnb1 interferon beta 1 JBrowse link 5 106,865,192 106,865,746 RGD:1624291
G Tbx21 T-box transcription factor 21 JBrowse link 10 85,032,799 85,049,331 RGD:1624291
negative regulation of type I hypersensitivity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fcgr2b Fc fragment of IgG receptor IIb JBrowse link 13 89,329,298 89,343,916 RGD:1624291
negative regulation of type IV hypersensitivity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Il20rb interleukin 20 receptor subunit beta JBrowse link 8 108,745,906 108,778,561 RGD:1624291
G Spn sialophorin JBrowse link 1 198,572,999 198,585,664 RGD:1624291
peripheral T cell tolerance induction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aire autoimmune regulator JBrowse link 20 11,365,630 11,380,636 RGD:1624291
RGD:13792537
positive regulation of antibody-dependent cellular cytotoxicity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G RT1-S3 RT1 class Ib, locus S3 JBrowse link 20 3,176,124 3,180,825 RGD:1624291
positive regulation of germinal center formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ada adenosine deaminase JBrowse link 3 160,115,840 160,139,947 RGD:1624291
G LOC100909593 class II histocompatibility antigen, M alpha chain-like JBrowse link 20 3,935,501 3,938,915 RGD:1624291
G RT1-DMa RT1 class II, locus DMa JBrowse link 20 3,935,512 3,938,915 RGD:1624291
G Tnfrsf13c TNF receptor superfamily member 13C JBrowse link 7 123,453,799 123,456,289 RGD:1624291
G Tnfsf13 TNF superfamily member 13 JBrowse link 10 56,286,964 56,290,680 RGD:1624291
G Tnfsf13b TNF superfamily member 13b JBrowse link 16 85,275,690 85,306,419 RGD:1624291
positive regulation of humoral immune response mediated by circulating immunoglobulin term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fcer2 Fc fragment of IgE receptor II JBrowse link 12 2,233,772 2,245,324 RGD:1624291
G Gimap5 GTPase, IMAP family member 5 JBrowse link 4 78,377,228 78,386,683 RGD:2303774
G Hpx hemopexin JBrowse link 1 170,423,558 170,431,066 RGD:1624291
G Lta lymphotoxin alpha JBrowse link 20 4,851,889 4,854,677 RGD:1624291
G Nod2 nucleotide-binding oligomerization domain containing 2 JBrowse link 19 19,342,061 19,389,366 RGD:1624291
G Ptprc protein tyrosine phosphatase, receptor type, C JBrowse link 13 55,061,561 55,174,150 RGD:1624291
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:1624291
positive regulation of immunoglobulin mediated immune response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AABR07032888.1 RGD:13792537
G Cd226 CD226 molecule JBrowse link 18 86,299,392 86,394,772 RGD:1624291
RGD:13792537
G Nectin2 nectin cell adhesion molecule 2 JBrowse link 1 80,631,449 80,666,617 RGD:1624291
G Tnfsf4 TNF superfamily member 4 JBrowse link 13 79,269,973 79,293,775 RGD:1624291
positive regulation of immunoglobulin production in mucosal tissue term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G LOC688282 hypothetical protein LOC688282 JBrowse link 10 106,800,040 106,810,153 RGD:1624291
G Xcl1 X-C motif chemokine ligand 1 JBrowse link 13 83,199,402 83,202,845 RGD:1624291
RGD:1600115
positive regulation of interleukin-4-dependent isotype switching to IgE isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Tnfsf4 TNF superfamily member 4 JBrowse link 13 79,269,973 79,293,775 RGD:1624291
positive regulation of isotype switching term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Exosc3 exosome component 3 JBrowse link 5 60,866,498 60,871,734 RGD:1624291
G Exosc6 exosome component 6 JBrowse link 19 43,190,879 43,193,164 RGD:1624291
G Hmces 5-hydroxymethylcytosine binding, ES cell specific JBrowse link 4 119,841,088 119,864,115 RGD:1600115
RGD:1624291
G Kmt5b lysine methyltransferase 5B JBrowse link 1 219,000,844 219,050,211 RGD:1600115
RGD:1624291
G Kmt5c lysine methyltransferase 5C JBrowse link 1 72,666,662 72,674,271 RGD:1600115
RGD:1624291
G Mad2l2 mitotic arrest deficient 2 like 2 JBrowse link 5 164,943,183 164,956,255 RGD:1624291
G Paxip1 PAX interacting protein 1 JBrowse link 4 3,956,931 4,008,326 RGD:1624291
G Rif1 replication timing regulatory factor 1 JBrowse link 3 37,599,540 37,648,818 RGD:1624291
G Shld1 shieldin complex subunit 1 JBrowse link 3 125,318,682 125,396,705 RGD:1624291
RGD:13792537
G Shld2 shieldin complex subunit 2 JBrowse link 16 10,570,307 10,661,528 RGD:1624291
G Tfrc transferrin receptor JBrowse link 11 71,397,423 71,419,263 RGD:1624291
RGD:1600115
G Tp53bp1 tumor protein p53 binding protein 1 JBrowse link 3 113,160,030 113,259,701 RGD:1624291
positive regulation of isotype switching to IgA isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mlh1 mutL homolog 1 JBrowse link 8 119,486,655 119,523,716 RGD:1600115
RGD:1624291
G Msh2 mutS homolog 2 JBrowse link 6 11,215,951 11,274,916 RGD:1600115
RGD:1624291
G Nsd2 nuclear receptor binding SET domain protein 2 JBrowse link 14 82,119,210 82,196,501 RGD:1624291
G Pms2 PMS1 homolog 2, mismatch repair system component JBrowse link 12 12,714,394 12,738,654 RGD:1624291
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:1624291
RGD:1600115
G Tnfsf13 TNF superfamily member 13 JBrowse link 10 56,286,964 56,290,680 RGD:1624291
positive regulation of isotype switching to IgE isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Clcf1 cardiotrophin-like cytokine factor 1 JBrowse link 1 219,468,866 219,472,445 RGD:1624291
G Il4 interleukin 4 JBrowse link 10 38,963,979 38,969,531 RGD:1624291
G Stat6 signal transducer and activator of transcription 6 JBrowse link 7 70,946,228 70,963,542 RGD:1624291
positive regulation of isotype switching to IgG isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atad5 ATPase family, AAA domain containing 5 JBrowse link 10 67,427,042 67,475,825 RGD:1624291
G Cd28 Cd28 molecule JBrowse link 9 67,546,408 67,573,858 RGD:1624291
RGD:1600115
G Cd40 CD40 molecule JBrowse link 3 161,519,789 161,534,943 RGD:1624291
G Ifng interferon gamma JBrowse link 7 61,337,383 61,341,419 RGD:1624291
G Il2 interleukin 2 JBrowse link 2 123,847,150 123,851,854 RGD:1624291
G Il4 interleukin 4 JBrowse link 10 38,963,979 38,969,531 RGD:1624291
G Mlh1 mutL homolog 1 JBrowse link 8 119,486,655 119,523,716 RGD:1600115
RGD:1624291
G Msh2 mutS homolog 2 JBrowse link 6 11,215,951 11,274,916 RGD:1600115
RGD:1624291
G Pagr1 Paxip1-associated glutamate-rich protein 1 JBrowse link 1 198,448,790 198,451,078 RGD:1624291
G Paxip1 PAX interacting protein 1 JBrowse link 4 3,956,931 4,008,326 RGD:1624291
G Pms2 PMS1 homolog 2, mismatch repair system component JBrowse link 12 12,714,394 12,738,654 RGD:1624291
G Ptprc protein tyrosine phosphatase, receptor type, C JBrowse link 13 55,061,561 55,174,150 RGD:1624291
G Tbx21 T-box transcription factor 21 JBrowse link 10 85,032,799 85,049,331 RGD:1624291
positive regulation of peripheral T cell tolerance induction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Foxp3 forkhead box P3 JBrowse link X 15,753,175 15,768,648 RGD:1624291
positive regulation of T cell cytokine production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G B2m beta-2 microglobulin JBrowse link 3 114,087,287 114,093,311 RGD:1624291
G Fzd5 frizzled class receptor 5 JBrowse link 9 71,443,784 71,445,541 RGD:1624291
RGD:1600115
G LOC100364500 RT1 class I, locus CE11-like JBrowse link 20 2,704,153 2,707,111 RGD:1624291
G Malt1 MALT1 paracaspase JBrowse link 18 61,108,712 61,162,446 RGD:1624291
G Map3k7 mitogen activated protein kinase kinase kinase 7 JBrowse link 5 47,183,142 47,244,424 RGD:1624291
G Sash3 SAM and SH3 domain containing 3 JBrowse link X 134,979,637 134,994,351 RGD:1624291
G Tnfsf4 TNF superfamily member 4 JBrowse link 13 79,269,973 79,293,775 RGD:1624291
G Traf2 Tnf receptor-associated factor 2 JBrowse link 3 2,746,061 2,770,690 RGD:1624291
G Traf6 TNF receptor associated factor 6 JBrowse link 3 91,252,829 91,271,607 RGD:1624291
G Xcl1 X-C motif chemokine ligand 1 JBrowse link 13 83,199,402 83,202,845 RGD:1624291
positive regulation of T cell mediated cytotoxicity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AABR07044397.1 RGD:13792537
G AABR07044404.1 RGD:13792537
G Azgp1 alpha-2-glycoprotein 1, zinc-binding JBrowse link 12 19,196,565 19,203,094 RGD:13792537
G B2m beta-2 microglobulin JBrowse link 3 114,087,287 114,093,311 RGD:1624291
G Cd1d1 CD1d1 molecule JBrowse link 2 186,330,298 186,333,805 RGD:1624291
RGD:13792537
G Cyrib CYFIP related Rac1 interactor B JBrowse link 7 104,514,566 104,641,875 RGD:1624291
RGD:1600115
G Fadd Fas associated via death domain JBrowse link 1 217,746,176 217,748,581 RGD:1624291
RGD:1600115
G Fcgrt Fc fragment of IgG receptor and transporter JBrowse link 1 101,086,872 101,096,159 RGD:13792537
G Hfe homeostatic iron regulator JBrowse link 17 43,661,276 43,669,327 RGD:13792537
G Hspa1b heat shock protein family A (Hsp70) member 1B JBrowse link 20 4,877,638 4,880,112 RGD:1298959
G Hspa8 heat shock protein family A (Hsp70) member 8 JBrowse link 8 44,989,401 44,993,261 RGD:10059395
G Il12a interleukin 12A JBrowse link 2 165,076,945 165,083,996 RGD:1624291
RGD:1600115
G Il12b interleukin 12B JBrowse link 10 30,034,447 30,048,774 RGD:1624291
G Il23a interleukin 23 subunit alpha JBrowse link 7 2,710,609 2,712,723 RGD:1624291
G LOC100364500 RT1 class I, locus CE11-like JBrowse link 20 2,704,153 2,707,111 RGD:1624291
G LOC100909797 RT1 class I histocompatibility antigen, AA alpha chain-like JBrowse link 20 3,242,236 3,253,995 RGD:1624291
G Micb MHC class I polypeptide-related sequence B JBrowse link 1 79,754,587 79,772,092 RGD:13792537
G Mill1 MHC I like leukocyte 1 JBrowse link 1 79,631,266 79,657,943 RGD:13792537
G P2rx7 purinergic receptor P2X 7 JBrowse link 12 39,353,613 39,396,042 RGD:1624291
G Ptprc protein tyrosine phosphatase, receptor type, C JBrowse link 13 55,061,561 55,174,150 RGD:1624291
G RT1-A1 RT1 class Ia, locus A1 JBrowse link 20 5,414,463 5,418,012 RGD:2313503
RGD:13792537
G RT1-A2 RT1 class Ia, locus A2 JBrowse link 20 5,374,990 5,378,536 RGD:1624291
RGD:13792537
G RT1-CE10 RT1 class I, locus CE10 JBrowse link 20 129,192 157,689 RGD:13792537
G RT1-CE3 RT1 class I, locus CE3 JBrowse link 20 4,918,047 4,943,603 RGD:13792537
G RT1-CE4 RT1 class I, locus CE4 JBrowse link 20 4,918,523 4,921,339 RGD:13792537
G RT1-CE5 RT1 class I, locus CE5 JBrowse link 20 4,892,702 4,896,993 RGD:1624291
RGD:13792537
G RT1-EC2 RT1 class Ib, locus EC2 RGD:13792537
G RT1-M2 RT1 class Ib, locus M2 JBrowse link 20 1,337,242 1,339,488 RGD:13792537
G RT1-M3-1 RT1 class Ib, locus M3, gene 1 JBrowse link 20 1,814,661 1,833,033 RGD:13792537
G RT1-M4 RT1 class Ib, locus M4 JBrowse link 20 2,043,710 2,048,575 RGD:13792537
G RT1-M5 RT1 class Ib, locus M5 JBrowse link 20 2,038,158 2,040,422 RGD:13792537
G RT1-M6-2 RT1 class I, locus M6, gene 2 JBrowse link 20 2,075,796 2,079,183 RGD:13792537
G RT1-N2 RT1 class Ib, locus N2 JBrowse link 20 3,146,579 3,150,852 RGD:13792537
G RT1-N3 RT1 class Ib, locus N3 JBrowse link 20 3,166,793 3,170,945 RGD:13792537
G RT1-S2 RT1 class Ib, locus S2 JBrowse link 20 3,152,073 3,165,871 RGD:13792537
G RT1-S3 RT1 class Ib, locus S3 JBrowse link 20 3,176,124 3,180,825 RGD:1624291
RGD:13792537
G RT1-T24-1 RT1 class I, locus T24, gene 1 JBrowse link 20 3,269,315 3,282,523 RGD:13792537
G RT1-T24-3 RT1 class I, locus T24, gene 3 JBrowse link 20 3,226,010 3,257,254 RGD:13792537
G RT1-T24-4 RT1 class I, locus T24, gene 4 JBrowse link 20 3,189,457 3,197,457 RGD:13792537
G Stx7 syntaxin 7 JBrowse link 1 22,241,655 22,281,850 RGD:1624291
G Tap2 transporter 2, ATP binding cassette subfamily B member JBrowse link 20 3,995,544 4,009,587 RGD:1299069
RGD:1624291
G Xcl1 X-C motif chemokine ligand 1 JBrowse link 13 83,199,402 83,202,845 RGD:1624291
positive regulation of T cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Slc22a13 solute carrier family 22 member 13 JBrowse link 8 127,885,268 127,900,829 RGD:1624291
positive regulation of T cell mediated immune response to tumor cell term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd24 CD24 molecule JBrowse link 20 48,335,540 48,340,847 RGD:1624291
G Fbxo38 F-box protein 38 JBrowse link 18 57,827,391 57,874,515 RGD:1624291
G Hspd1 heat shock protein family D (Hsp60) member 1 JBrowse link 9 61,680,529 61,691,202 RGD:1624291
positive regulation of T cell mediated immunity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ptprc protein tyrosine phosphatase, receptor type, C JBrowse link 13 55,061,561 55,174,150 RGD:1624291
G Zbtb1 zinc finger and BTB domain containing 1 JBrowse link 6 99,401,775 99,425,739 RGD:1624291
positive regulation of T-helper 1 cell cytokine production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arid5a AT-rich interaction domain 5A JBrowse link 9 42,871,907 42,886,725 RGD:1624291
G Il18 interleukin 18 JBrowse link 8 55,009,666 55,016,286 RGD:1600115
RGD:1624291
G Il18r1 interleukin 18 receptor 1 JBrowse link 9 47,184,404 47,217,403 RGD:1624291
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:1600115
RGD:1624291
G Il1r1 interleukin 1 receptor type 1 JBrowse link 9 46,962,291 47,038,139 RGD:1600115
RGD:1624291
G Xcl1 X-C motif chemokine ligand 1 JBrowse link 13 83,199,402 83,202,845 RGD:1624291
RGD:1600115
positive regulation of T-helper 1 cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Anxa1 annexin A1 JBrowse link 1 237,893,983 237,910,002 RGD:1624291
RGD:13792537
RGD:1600115
G Ccl19 C-C motif chemokine ligand 19 JBrowse link 5 58,181,025 58,182,969 RGD:1624291
G Hlx H2.0-like homeobox JBrowse link 13 102,637,967 102,643,376 RGD:1624291
G Ripk2 receptor-interacting serine-threonine kinase 2 JBrowse link 5 29,838,713 29,870,390 RGD:1624291
G Socs5 suppressor of cytokine signaling 5 JBrowse link 6 10,671,311 10,705,610 RGD:1624291
positive regulation of T-helper 1 type immune response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ccr2 C-C motif chemokine receptor 2 RGD:1624291
RGD:1600115
G Il12b interleukin 12B JBrowse link 10 30,034,447 30,048,774 RGD:1624291
G Il12rb1 interleukin 12 receptor subunit beta 1 JBrowse link 16 20,370,722 20,383,576 RGD:1624291
G Il23a interleukin 23 subunit alpha JBrowse link 7 2,710,609 2,712,723 RGD:1624291
G Il23r interleukin 23 receptor JBrowse link 4 98,203,788 98,306,729 RGD:1624291
G Il27ra interleukin 27 receptor subunit alpha JBrowse link 19 25,151,835 25,163,995 RGD:1624291
G Nlrp10 NLR family, pyrin domain containing 10 JBrowse link 1 173,521,412 173,528,969 RGD:1624291
G Pla2g4a phospholipase A2 group IVA JBrowse link 13 67,062,252 67,206,688 RGD:1600115
RGD:1624291
G Ripk2 receptor-interacting serine-threonine kinase 2 JBrowse link 5 29,838,713 29,870,390 RGD:1624291
G RT1-Bb RT1 class II, locus Bb JBrowse link 20 4,043,726 4,049,367 RGD:1624291
RGD:1600115
G Slc11a1 solute carrier family 11 member 1 JBrowse link 9 81,655,590 81,666,697 RGD:1624291
RGD:1600115
positive regulation of T-helper 17 cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Malt1 MALT1 paracaspase JBrowse link 18 61,108,712 61,162,446 RGD:1624291
G Mir326 microRNA 326 JBrowse link 1 164,518,401 164,518,495 RGD:1624291
G Nfkbid NFKB inhibitor delta JBrowse link 1 88,883,816 88,892,543 RGD:1624291
G Nfkbiz NFKB inhibitor zeta JBrowse link 11 47,243,342 47,271,487 RGD:1624291
G Nlrp3 NLR family, pyrin domain containing 3 JBrowse link 10 45,884,324 45,918,290 RGD:1624291
positive regulation of T-helper 17 cell lineage commitment term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Il23a interleukin 23 subunit alpha JBrowse link 7 2,710,609 2,712,723 RGD:1624291
RGD:13792537
positive regulation of T-helper 17 type immune response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arid5a AT-rich interaction domain 5A JBrowse link 9 42,871,907 42,886,725 RGD:1624291
G Il23a interleukin 23 subunit alpha JBrowse link 7 2,710,609 2,712,723 RGD:1624291
G Mir301a microRNA 301a JBrowse link 10 74,417,746 74,417,845 RGD:1624291
G Nlrp10 NLR family, pyrin domain containing 10 JBrowse link 1 173,521,412 173,528,969 RGD:1624291
G Prkcq protein kinase C, theta JBrowse link 17 70,971,915 71,105,286 RGD:1600115
RGD:1624291
positive regulation of T-helper 2 cell cytokine production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd81 Cd81 molecule JBrowse link 1 216,237,663 216,253,460 RGD:1600115
RGD:1624291
G Gata3 GATA binding protein 3 JBrowse link 17 72,419,752 72,452,043 RGD:1624291
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:1624291
G Nlrp3 NLR family, pyrin domain containing 3 JBrowse link 10 45,884,324 45,918,290 RGD:1624291
G Prkcz protein kinase C, zeta JBrowse link 5 172,658,071 172,769,492 RGD:1624291
RGD:1600115
G Rsad2 radical S-adenosyl methionine domain containing 2 JBrowse link 6 45,655,947 45,669,083 RGD:1600115
RGD:1624291
G Xcl1 X-C motif chemokine ligand 1 JBrowse link 13 83,199,402 83,202,845 RGD:1624291
RGD:1600115
positive regulation of tolerance induction to nonself antigen term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G RT1-A1 RT1 class Ia, locus A1 JBrowse link 20 5,414,463 5,418,012 RGD:2313504
positive regulation of tolerance induction to tumor cell term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd274 CD274 molecule JBrowse link 1 247,519,890 247,539,659 RGD:1624291
positive regulation of type I hypersensitivity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Btk Bruton tyrosine kinase JBrowse link X 105,360,922 105,390,580 RGD:11040701
G Fcer1a Fc fragment of IgE receptor Ia JBrowse link 13 91,727,253 91,737,106 RGD:1624291
G Fcer1g Fc fragment of IgE receptor Ig JBrowse link 13 89,601,894 89,606,326 RGD:1624291
G Fcgr2a Fc fragment of IgG receptor IIa JBrowse link 13 91,146,878 91,163,691 RGD:1624291
G Ighg1 immunoglobulin heavy constant gamma 1 JBrowse link 6 139,140,572 139,784,388 RGD:1624291
positive regulation of type IIa hypersensitivity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G C3 complement C3 JBrowse link 9 9,721,137 9,747,084 RGD:1624291
RGD:1600115
G Fcer1g Fc fragment of IgE receptor Ig JBrowse link 13 89,601,894 89,606,326 RGD:1624291
G Fcgr1a Fc fragment of IgG receptor Ia JBrowse link 2 198,430,536 198,439,453 RGD:1624291
G Fcgr2a Fc fragment of IgG receptor IIa JBrowse link 13 91,146,878 91,163,691 RGD:1624291
G Ighg1 immunoglobulin heavy constant gamma 1 JBrowse link 6 139,140,572 139,784,388 RGD:1624291
positive regulation of type III hypersensitivity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Btk Bruton tyrosine kinase JBrowse link X 105,360,922 105,390,580 RGD:11040701
G Fcer1g Fc fragment of IgE receptor Ig JBrowse link 13 89,601,894 89,606,326 RGD:1624291
G Fcgr1a Fc fragment of IgG receptor Ia JBrowse link 2 198,430,536 198,439,453 RGD:1624291
G Fcgr2a Fc fragment of IgG receptor IIa JBrowse link 13 91,146,878 91,163,691 RGD:1624291
positive regulation of type IV hypersensitivity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Zp3 zona pellucida glycoprotein 3 JBrowse link 12 23,735,225 23,752,734 RGD:1600115
RGD:1624291
primary adaptive immune response involving T cells and B cells term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bach2 BTB domain and CNC homolog 2 JBrowse link 5 47,458,891 47,807,176 RGD:1624291
regulation of antibody-dependent cellular cytotoxicity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fcgr2a Fc fragment of IgG receptor IIa JBrowse link 13 91,146,878 91,163,691 RGD:2293335
regulation of complement activation, classical pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd55 CD55 molecule (Cromer blood group) JBrowse link 13 47,125,156 47,153,557 RGD:1624291
regulation of germinal center formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mef2c myocyte enhancer factor 2C JBrowse link 2 11,658,534 11,822,788 RGD:1600115
RGD:1624291
G Pkn1 protein kinase N1 JBrowse link 19 24,803,524 24,832,305 RGD:1624291
G Rc3h1 ring finger and CCCH-type domains 1 JBrowse link 13 78,723,028 78,794,663 RGD:1624291
G Tnfaip3 TNF alpha induced protein 3 JBrowse link 1 14,401,103 14,416,369 RGD:1624291
regulation of humoral immune response mediated by circulating immunoglobulin term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ptprc protein tyrosine phosphatase, receptor type, C JBrowse link 13 55,061,561 55,174,150 RGD:1624291
regulation of isotype switching term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aplf aprataxin and PNKP like factor JBrowse link 4 119,514,822 119,568,764 RGD:1624291
G Mir181b1 microRNA 181b-1 JBrowse link 13 54,952,903 54,953,012 RGD:1624291
G Mir181b2 microRNA 181b-2 JBrowse link 3 23,151,455 23,151,542 RGD:1624291
G Supt6h SPT6 homolog, histone chaperone and transcription elongation factor JBrowse link 10 65,470,470 65,507,581 RGD:1624291
regulation of isotype switching to IgG isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Foxp3 forkhead box P3 JBrowse link X 15,753,175 15,768,648 RGD:1624291
G Il27ra interleukin 27 receptor subunit alpha JBrowse link 19 25,151,835 25,163,995 RGD:1624291
G Ndfip1 Nedd4 family interacting protein 1 JBrowse link 18 31,574,759 31,625,286 RGD:1624291
regulation of T cell antigen processing and presentation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Was WASP actin nucleation promoting factor JBrowse link X 15,155,246 15,164,099 RGD:1624291
regulation of T cell cytokine production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ccl20 C-C motif chemokine ligand 20 JBrowse link 9 88,918,359 88,921,017 RGD:1624291
G Ccr2 C-C motif chemokine receptor 2 RGD:1600115
RGD:1624291
G Tnfrsf1b TNF receptor superfamily member 1B JBrowse link 5 163,136,390 163,167,299 RGD:1624291
G Trpm4 transient receptor potential cation channel, subfamily M, member 4 JBrowse link 1 101,293,300 101,323,484 RGD:1600115
RGD:1624291
regulation of T cell mediated cytotoxicity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ager advanced glycosylation end product-specific receptor JBrowse link 20 4,363,152 4,366,079 RGD:1600115
RGD:1624291
G Ripk3 receptor-interacting serine-threonine kinase 3 JBrowse link 15 34,470,796 34,479,741 RGD:1624291
RGD:1600115
regulation of T cell mediated immune response to tumor cell term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hmgb1 high mobility group box 1 JBrowse link 12 7,082,529 7,090,246 RGD:1624291
RGD:1600115
regulation of T cell mediated immunity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dpp4 dipeptidylpeptidase 4 JBrowse link 3 48,291,055 48,372,672 RGD:1626458
regulation of T-helper 1 cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Il27 interleukin 27 JBrowse link 1 198,003,615 198,010,112 RGD:1624291
RGD:13792537
regulation of T-helper 17 cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ccl20 C-C motif chemokine ligand 20 JBrowse link 9 88,918,359 88,921,017 RGD:1624291
G Ccr6 C-C motif chemokine receptor 6 JBrowse link 1 53,063,380 53,087,519 RGD:1624291
G Mir301a microRNA 301a JBrowse link 10 74,417,746 74,417,845 RGD:1624291
regulation of T-helper 17 type immune response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lgals9 galectin 9 JBrowse link 10 64,737,022 64,760,195 RGD:1624291
G Otud5 OTU deubiquitinase 5 JBrowse link X 15,471,212 15,504,372 RGD:1624291
regulation of tolerance induction dependent upon immune response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Havcr2 hepatitis A virus cellular receptor 2 JBrowse link 10 31,561,838 31,590,624 RGD:1624291
regulation of type IV hypersensitivity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fut7 fucosyltransferase 7 JBrowse link 3 2,637,281 2,646,497 RGD:1624291
somatic recombination of immunoglobulin genes involved in immune response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mlh1 mutL homolog 1 JBrowse link 8 119,486,655 119,523,716 RGD:1624291
G Msh2 mutS homolog 2 JBrowse link 6 11,215,951 11,274,916 RGD:1624291
RGD:13792537
susceptibility to T cell mediated cytotoxicity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nectin2 nectin cell adhesion molecule 2 JBrowse link 1 80,631,449 80,666,617 RGD:1624291
G Pvr PVR cell adhesion molecule JBrowse link 1 80,820,306 80,835,712 RGD:1624291
RGD:13792537
T cell antigen processing and presentation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Icam1 intercellular adhesion molecule 1 JBrowse link 8 22,035,287 22,047,049 RGD:1624291
G Kdm5d lysine demethylase 5D JBrowse link Y 501,058 589,267 RGD:1624291
G Rftn1 raftlin lipid raft linker 1 JBrowse link 9 12,740,885 12,942,358 RGD:1624291
G Treml4 triggering receptor expressed on myeloid cells-like 4 JBrowse link 9 14,668,691 14,707,122 RGD:1624291
G Trex1 three prime repair exonuclease 1 JBrowse link 8 117,796,127 117,797,427 RGD:1624291
T cell cytokine production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dlg1 discs large MAGUK scaffold protein 1 JBrowse link 11 72,164,566 72,378,895 RGD:1624291
RGD:1600115
G Kdelr1 KDEL endoplasmic reticulum protein retention receptor 1 JBrowse link 1 101,859,346 101,870,232 RGD:1624291
G Slc11a1 solute carrier family 11 member 1 JBrowse link 9 81,655,590 81,666,697 RGD:1624291
RGD:1600115
T cell mediated cytotoxicity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cadm1 cell adhesion molecule 1 JBrowse link 8 51,858,906 52,200,591 RGD:1624291
G Crtam cytotoxic and regulatory T cell molecule JBrowse link 8 45,152,584 45,216,082 RGD:1624291
G Ctsc cathepsin C JBrowse link 1 151,918,514 151,949,979 RGD:1624291
G Ctsh cathepsin H JBrowse link 8 97,439,155 97,458,293 RGD:1624291
RGD:1600115
G Emp2 epithelial membrane protein 2 JBrowse link 10 5,433,248 5,467,840 RGD:1624291
RGD:1600115
G Gzmb granzyme B JBrowse link 15 35,413,862 35,417,293 RGD:1624291
G Gzmm granzyme M JBrowse link 7 12,893,431 12,899,004 RGD:1624291
RGD:1600115
G Hprt1 hypoxanthine phosphoribosyltransferase 1 JBrowse link X 158,196,640 158,228,815 RGD:1624291
G LOC100364500 RT1 class I, locus CE11-like JBrowse link 20 2,704,153 2,707,111 RGD:1624291
G Mill1 MHC I like leukocyte 1 JBrowse link 1 79,631,266 79,657,943 RGD:1624291
G Prf1 perforin 1 JBrowse link 20 30,915,294 30,920,804 RGD:1624291
RGD:1600115
G Raet1e retinoic acid early transcript 1E JBrowse link 1 1,101,666 1,120,340 RGD:1624291
G Serpinb9 serpin family B member 9 JBrowse link 17 32,648,846 32,673,047 RGD:1624291
G Spag6l sperm associated antigen 6-like JBrowse link 11 88,424,493 88,517,910 RGD:1600115
G Stx11 syntaxin 11 JBrowse link 1 7,039,160 7,064,870 RGD:1624291
G Tsta3 tissue specific transplantation antigen P35B JBrowse link 7 116,958,427 116,963,281 RGD:1624291
T cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G LOC100364500 RT1 class I, locus CE11-like JBrowse link 20 2,704,153 2,707,111 RGD:1624291
T cell mediated immunity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd46 CD46 molecule JBrowse link 13 113,786,525 113,818,741 RGD:1624291
G Cd70 Cd70 molecule JBrowse link 9 9,842,585 9,845,728 RGD:1624291
G Cd8a CD8a molecule JBrowse link 4 99,217,640 99,243,352 RGD:1624291
RGD:13792537
G Cdh17 cadherin 17 JBrowse link 5 25,354,187 25,443,675 RGD:1624291
G Ephb6 Eph receptor B6 JBrowse link 4 70,903,253 70,918,514 RGD:1624291
G Foxp3 forkhead box P3 JBrowse link X 15,753,175 15,768,648 RGD:1624291
G Jag1 jagged canonical Notch ligand 1 JBrowse link 3 130,079,361 130,114,781 RGD:1600115
RGD:1624291
G Lyst lysosomal trafficking regulator JBrowse link 17 90,323,055 90,522,091 RGD:1624291
G Myo1g myosin IG JBrowse link 14 86,781,243 86,796,393 RGD:1624291
G Ntn1 netrin 1 JBrowse link 10 54,761,925 54,982,072 RGD:1600115
T-helper 1 cell cytokine production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Il12a interleukin 12A JBrowse link 2 165,076,945 165,083,996 RGD:1624291
RGD:1600115
G Il12b interleukin 12B JBrowse link 10 30,034,447 30,048,774 RGD:1624291
G Il18 interleukin 18 JBrowse link 8 55,009,666 55,016,286 RGD:1624291
RGD:1600115
G Il18rap interleukin 18 receptor accessory protein JBrowse link 9 47,225,543 47,255,805 RGD:1624291
G Slamf1 signaling lymphocytic activation molecule family member 1 JBrowse link 13 90,184,545 90,219,170 RGD:1624291
T-helper 1 cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hmgb1 high mobility group box 1 JBrowse link 12 7,082,529 7,090,246 RGD:1624291
G Il18r1 interleukin 18 receptor 1 JBrowse link 9 47,184,404 47,217,403 RGD:1624291
G Lef1 lymphoid enhancer binding factor 1 JBrowse link 2 236,232,115 236,345,061 RGD:1600115
RGD:1624291
G Relb RELB proto-oncogene, NF-kB subunit JBrowse link 1 80,517,081 80,545,019 RGD:1624291
G Sema4a semaphorin 4A JBrowse link 2 187,799,568 187,823,014 RGD:1624291
G Tmem98 transmembrane protein 98 JBrowse link 10 68,173,380 68,184,289 RGD:1600115
RGD:1624291
T-helper 1 cell lineage commitment term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Il4 interleukin 4 JBrowse link 10 38,963,979 38,969,531 RGD:1624291
G Mtor mechanistic target of rapamycin kinase JBrowse link 5 165,263,813 165,373,967 RGD:1624291
G Spn sialophorin JBrowse link 1 198,572,999 198,585,664 RGD:1600115
RGD:1624291
G Stat6 signal transducer and activator of transcription 6 JBrowse link 7 70,946,228 70,963,542 RGD:1624291
T-helper 1 type immune response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bcl3 BCL3, transcription coactivator JBrowse link 1 80,730,758 80,745,273 RGD:1624291
G Hras HRas proto-oncogene, GTPase JBrowse link 1 214,178,404 214,181,841 RGD:1624291
G Il18 interleukin 18 JBrowse link 8 55,009,666 55,016,286 RGD:1624291
RGD:8554620
G Il18bp interleukin 18 binding protein JBrowse link 1 167,091,521 167,095,727 RGD:1624291
RGD:13792537
G Nras NRAS proto-oncogene, GTPase JBrowse link 2 205,553,119 205,563,716 RGD:1624291
G Relb RELB proto-oncogene, NF-kB subunit JBrowse link 1 80,517,081 80,545,019 RGD:1624291
G RT1-Db1 RT1 class II, locus Db1 JBrowse link 20 4,087,621 4,097,190 RGD:1624291
G Traf6 TNF receptor associated factor 6 JBrowse link 3 91,252,829 91,271,607 RGD:1624291
G Vegfa vascular endothelial growth factor A JBrowse link 9 17,340,341 17,355,681 RGD:1580562
T-helper 17 cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Batf basic leucine zipper ATF-like transcription factor JBrowse link 6 109,562,415 109,584,541 RGD:1600115
RGD:1624291
G Rora RAR-related orphan receptor A JBrowse link 8 75,515,886 75,616,477 RGD:1624291
G Rorc RAR-related orphan receptor C JBrowse link 2 195,612,471 195,636,797 RGD:1624291
T-helper 17 cell lineage commitment term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Batf basic leucine zipper ATF-like transcription factor JBrowse link 6 109,562,415 109,584,541 RGD:1600115
RGD:1624291
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:1624291
RGD:1600115
G Irf4 interferon regulatory factor 4 JBrowse link 17 34,886,746 34,905,191 RGD:1624291
G Ly9 lymphocyte antigen 9 JBrowse link 13 90,002,779 90,022,346 RGD:1624291
G Otud5 OTU deubiquitinase 5 JBrowse link X 15,471,212 15,504,372 RGD:1624291
G Slamf6 SLAM family member 6 JBrowse link 13 90,300,160 90,321,781 RGD:1624291
G Stat3 signal transducer and activator of transcription 3 JBrowse link 10 88,790,401 88,842,263 RGD:1624291
RGD:1600115
T-helper 2 cell cytokine production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Crlf2 cytokine receptor-like factor 2 JBrowse link 14 1,456,843 1,461,543 RGD:1624291
G Dennd1b DENN domain containing 1B JBrowse link 13 56,015,813 56,242,041 RGD:1624291
RGD:13792537
G Il31ra interleukin 31 receptor A JBrowse link 2 44,333,347 44,408,005 RGD:1624291
G Il4 interleukin 4 JBrowse link 10 38,963,979 38,969,531 RGD:1624291
G Stard7 StAR-related lipid transfer domain containing 7 JBrowse link 3 119,698,655 119,727,303 RGD:1600115
RGD:1624291
tolerance induction to nonself antigen term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G C3ar1 complement C3a receptor 1 JBrowse link 4 155,681,767 155,691,240 RGD:5129547
type IV hypersensitivity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ephb6 Eph receptor B6 JBrowse link 4 70,903,253 70,918,514 RGD:1624291
G Gata3 GATA binding protein 3 JBrowse link 17 72,419,752 72,452,043 RGD:2314191

Term paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.