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ONTOLOGY REPORT - ANNOTATIONS


Term:tolerance induction
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Accession:GO:0002507 term browser browse the term
Definition:A process that directly activates any of the steps required for tolerance, a physiologic state in which the immune system does not react destructively against the components of an organism that harbors it or against antigens that are introduced to it.


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tolerance induction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G C3 complement C3 JBrowse link 9 9,721,137 9,747,084 RGD:5129541
G Ccr4 C-C motif chemokine receptor 4 JBrowse link 8 122,530,152 122,535,959 RGD:1624291
G Foxp3 forkhead box P3 JBrowse link X 15,753,175 15,768,648 RGD:1624291
central tolerance induction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Foxj1 forkhead box J1 JBrowse link 10 105,282,090 105,289,396 RGD:1624291
central tolerance induction to self antigen term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aire autoimmune regulator JBrowse link 20 11,365,630 11,380,636 RGD:1624291
RGD:13792537
natural killer cell tolerance induction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Havcr2 hepatitis A virus cellular receptor 2 JBrowse link 10 31,561,838 31,590,624 RGD:1624291
G Lgals9 galectin 9 JBrowse link 10 64,737,022 64,760,195 RGD:1624291
G RT1-S3 RT1 class Ib, locus S3 JBrowse link 20 3,176,124 3,180,825 RGD:1624291
negative regulation of T cell anergy term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd86 CD86 molecule JBrowse link 11 67,060,305 67,117,990 RGD:4892228
negative regulation of tolerance induction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pdcd1 programmed cell death 1 JBrowse link 9 101,305,742 101,319,937 RGD:1624291
peripheral T cell tolerance induction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aire autoimmune regulator JBrowse link 20 11,365,630 11,380,636 RGD:1624291
RGD:13792537
positive regulation of B cell tolerance induction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Tgfbr2 transforming growth factor, beta receptor 2 JBrowse link 8 124,310,288 124,399,345 RGD:1624291
positive regulation of central B cell tolerance induction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Foxj1 forkhead box J1 JBrowse link 10 105,282,090 105,289,396 RGD:1624291
positive regulation of macrophage tolerance induction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Irak3 interleukin-1 receptor-associated kinase 3 JBrowse link 7 64,922,830 64,982,224 RGD:1624291
positive regulation of peripheral T cell tolerance induction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Foxp3 forkhead box P3 JBrowse link X 15,753,175 15,768,648 RGD:1624291
positive regulation of T cell anergy term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cblb Cbl proto-oncogene B JBrowse link 11 51,037,383 51,202,761 RGD:1624291
G Cd3e CD3e molecule JBrowse link 8 49,297,604 49,309,370 RGD:1624291
G Foxp3 forkhead box P3 JBrowse link X 15,753,175 15,768,648 RGD:1624291
G Itch itchy E3 ubiquitin protein ligase JBrowse link 3 150,660,665 150,752,016 RGD:1624291
positive regulation of T cell tolerance induction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Foxp3 forkhead box P3 JBrowse link X 15,753,175 15,768,648 RGD:1624291
G Ido1 indoleamine 2,3-dioxygenase 1 JBrowse link 16 72,216,326 72,228,098 RGD:1624291
RGD:1600115
G Lilrb2 leukocyte immunoglobulin like receptor B2 JBrowse link 1 63,734,135 63,741,986 RGD:1624291
G Tgfbr2 transforming growth factor, beta receptor 2 JBrowse link 8 124,310,288 124,399,345 RGD:1624291
positive regulation of tolerance induction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lilrb2 leukocyte immunoglobulin like receptor B2 JBrowse link 1 63,734,135 63,741,986 RGD:1624291
positive regulation of tolerance induction to nonself antigen term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G RT1-A1 RT1 class Ia, locus A1 JBrowse link 20 5,414,463 5,418,012 RGD:2313504
positive regulation of tolerance induction to self antigen term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Tgfbr2 transforming growth factor, beta receptor 2 JBrowse link 8 124,310,288 124,399,345 RGD:1624291
positive regulation of tolerance induction to tumor cell term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd274 CD274 molecule JBrowse link 1 247,519,890 247,539,659 RGD:1624291
regulation of T cell anergy term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Foxp3 forkhead box P3 JBrowse link X 15,753,175 15,768,648 RGD:1624291
G Phlpp1 PH domain and leucine rich repeat protein phosphatase 1 JBrowse link 13 26,145,989 26,394,505 RGD:1600115
RGD:1624291
G Runx1 RUNX family transcription factor 1 JBrowse link 11 32,765,147 33,003,061 RGD:1624291
regulation of T cell tolerance induction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Il2ra interleukin 2 receptor subunit alpha JBrowse link 17 70,500,672 70,547,929 RGD:1624291
regulation of tolerance induction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hmgb1 high mobility group box 1 JBrowse link 12 7,082,529 7,090,246 RGD:1624291
G Marchf7 membrane associated ring-CH-type finger 7 JBrowse link 3 46,284,961 46,325,230 RGD:1624291
regulation of tolerance induction dependent upon immune response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Havcr2 hepatitis A virus cellular receptor 2 JBrowse link 10 31,561,838 31,590,624 RGD:1624291
T cell tolerance induction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Icos inducible T-cell co-stimulator JBrowse link 9 67,748,157 67,786,808 RGD:1624271
RGD:13792537
G RT1-A1 RT1 class Ia, locus A1 JBrowse link 20 5,414,463 5,418,012 RGD:2313504
tolerance induction to lipopolysaccharide term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acod1 aconitate decarboxylase 1 JBrowse link 15 93,612,968 93,622,322 RGD:1624291
G Tnfaip3 TNF alpha induced protein 3 JBrowse link 1 14,401,103 14,416,369 RGD:1624291
tolerance induction to nonself antigen term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G C3ar1 complement C3a receptor 1 JBrowse link 4 155,681,767 155,691,240 RGD:5129547
tolerance induction to self antigen term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Blk BLK proto-oncogene, Src family tyrosine kinase JBrowse link 15 46,555,552 46,593,778 RGD:13792537
G Foxp3 forkhead box P3 JBrowse link X 15,753,175 15,768,648 RGD:1624291
G Lyn LYN proto-oncogene, Src family tyrosine kinase JBrowse link 5 16,526,058 16,642,648 RGD:1624291
RGD:13792537
RGD:1600115
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19858
    immune system process 2798
      tolerance induction 31
        B cell tolerance induction + 2
        T cell tolerance induction + 14
        central tolerance induction + 2
        lymphocyte anergy + 7
        macrophage tolerance induction + 1
        natural killer cell tolerance induction + 3
        negative regulation of tolerance induction + 2
        positive regulation of tolerance induction + 11
        regulation of tolerance induction + 19
        tolerance induction dependent upon immune response + 6
        tolerance induction to lipopolysaccharide 2
        tolerance induction to self antigen + 6
Path 2
Term Annotations click to browse term
  biological_process 19858
    developmental process 6735
      anatomical structure development 6181
        multicellular organism development 5638
          system development 5212
            immune system development 1054
              tolerance induction 31
                B cell tolerance induction + 2
                T cell tolerance induction + 14
                central tolerance induction + 2
                lymphocyte anergy + 7
                macrophage tolerance induction + 1
                natural killer cell tolerance induction + 3
                negative regulation of tolerance induction + 2
                positive regulation of tolerance induction + 11
                regulation of tolerance induction + 19
                tolerance induction dependent upon immune response + 6
                tolerance induction to lipopolysaccharide 2
                tolerance induction to self antigen + 6
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.