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ONTOLOGY REPORT - ANNOTATIONS


Term:T cell tolerance induction
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Accession:GO:0002517 term browser browse the term
Definition:A process involving any mechanism for tolerance induction in T cells.
Synonyms:exact_synonym: T lymphocyte tolerance induction


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T cell tolerance induction term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Icos inducible T cell costimulator ISO RGD PMID:16220623 RGD:1624271 NCBI chrNW_004936631:562,650...572,263 JBrowse link
negative regulation of T cell anergy term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd86 CD86 molecule ISO RGD PMID:18424705 RGD:4892228 NCBI chrNW_004936536:8,414,491...8,481,712 JBrowse link
peripheral T cell tolerance induction term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aire autoimmune regulator ISO (MGI:MGI:5562496|PMID:23993652) UniProtKB PMID:23993652 MGI:MGI:5562496 NCBI chrNW_004936500:125,589...137,071 JBrowse link
positive regulation of peripheral T cell tolerance induction term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxp3 forkhead box P3 ISO (MGI:MGI:3662775|PMID:16532000) MGI PMID:16532000 MGI:MGI:3662775 NCBI chrNW_004936721:1,118,376...1,125,282 JBrowse link
positive regulation of T cell anergy term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cblb Cbl proto-oncogene B ISO (MGI:MGI:3038342|PMID:14973438) MGI PMID:14973438 MGI:MGI:3038342 NCBI chrNW_004936701:1,157,790...1,353,375 JBrowse link
G Cd3e CD3e molecule ISO (MGI:MGI:3038342|PMID:14973438) MGI PMID:14973438 MGI:MGI:3038342 NCBI chrNW_004936542:3,379,361...3,390,677 JBrowse link
G Foxp3 forkhead box P3 ISO (MGI:MGI:3692513|PMID:16945588) MGI PMID:16945588 MGI:MGI:3692513 NCBI chrNW_004936721:1,118,376...1,125,282 JBrowse link
G Itch itchy E3 ubiquitin protein ligase ISO (MGI:MGI:3038342|PMID:14973438) MGI PMID:14973438 MGI:MGI:3038342 NCBI chrNW_004936561:6,140,236...6,265,734 JBrowse link
positive regulation of T cell tolerance induction term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxp3 forkhead box P3 ISO (MGI:MGI:3692513|PMID:16945588) MGI PMID:16945588 MGI:MGI:3692513 NCBI chrNW_004936721:1,118,376...1,125,282 JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 ISO (MGI:MGI:1277518|PMID:9712583) MGI PMID:9712583 MGI:MGI:1277518 NCBI chrNW_004936843:658,058...672,662 JBrowse link
G Tgfbr2 transforming growth factor beta receptor 2 ISO (MGI:MGI:3686949|PMID:16973387) MGI PMID:16973387 MGI:MGI:3686949 NCBI chrNW_004936473:21,324,669...21,409,430 JBrowse link
regulation of T cell anergy term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxp3 forkhead box P3 ISO (MGI:MGI:3710039|PMID:17377532) UniProtKB PMID:17377532 MGI:MGI:3710039 NCBI chrNW_004936721:1,118,376...1,125,282 JBrowse link
G Phlpp1 PH domain and leucine rich repeat protein phosphatase 1 ISO (MGI:MGI:5013552|PMID:21498666) UniProtKB PMID:21498666 MGI:MGI:5013552 NCBI chrNW_004936497:2,467,776...2,683,794 JBrowse link
regulation of T cell tolerance induction term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il2ra interleukin 2 receptor subunit alpha ISO (PMID:23416241) UniProtKB PMID:23416241 NCBI chrNW_004936484:8,514,333...8,555,392 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12001
    immune system process 1919
      tolerance induction 27
        T cell tolerance induction 11
          T cell anergy + 6
          central T cell tolerance induction 0
          negative regulation of T cell tolerance induction + 1
          peripheral T cell tolerance induction + 2
          positive regulation of T cell tolerance induction + 6
          regulation of T cell tolerance induction + 9
Path 2
Term Annotations click to browse term
  biological_process 12001
    developmental process 5648
      anatomical structure development 5286
        multicellular organism development 4845
          system development 4567
            immune system development 932
              tolerance induction 27
                T cell tolerance induction 11
                  T cell anergy + 6
                  central T cell tolerance induction 0
                  negative regulation of T cell tolerance induction + 1
                  peripheral T cell tolerance induction + 2
                  positive regulation of T cell tolerance induction + 6
                  regulation of T cell tolerance induction + 9
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.