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ONTOLOGY REPORT - ANNOTATIONS


Term:arachidonic acid metabolite production involved in inflammatory response
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Accession:GO:0002538 term browser browse the term
Definition:The synthesis or release of products of arachidonic acid metabolism following a stimulus as part of an inflammatory response, resulting in an increase in their intracellular or extracellular levels.
Synonyms:exact_synonym: production of arachidonic acid metabolites involved in inflammatory response
 broad_synonym: arachidonic acid metabolite production involved in acute inflammatory response;   production of arachidonic acid metabolites involved in acute inflammatory response


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leukotriene production involved in inflammatory response term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alox5 arachidonate 5-lipoxygenase ISO
IEA
MGI:MGI:1933120 (MGI:MGI:86611|PMID:9091580)
GO_REF:0000107
RGD
Ensembl
PMID:9091580 GO_REF:0000107, MGI:MGI:86611 NCBI chr 4:148,398,004...148,446,308
Ensembl chr 4:148,398,892...148,446,303
JBrowse link
G Alox5ap arachidonate 5-lipoxygenase activating protein ISO MGI:MGI:2156546 (MGI:MGI:3721822|PMID:10779800), (MGI:MGI:86611|PMID:9091580) RGD PMID:9091580, PMID:10779800 MGI:MGI:3721822, MGI:MGI:86611 NCBI chr12:6,854,930...6,879,112
Ensembl chr12:6,854,920...6,879,154
JBrowse link
positive regulation of leukotriene production involved in inflammatory response term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Serpine1 serpin family E member 1 ISO
IEA
(PMID:19916862)
GO_REF:0000107
RGD
Ensembl
PMID:19916862 GO_REF:0000107 NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482
JBrowse link
prostaglandin production involved in inflammatory response term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ephx2 epoxide hydrolase 2 IMP RGD PMID:16962614 RGD:5688387 NCBI chr15:42,757,241...42,794,211
Ensembl chr15:42,757,235...42,794,279
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20017
    multicellular organismal process 9055
      production of molecular mediator involved in inflammatory response 87
        arachidonic acid metabolite production involved in inflammatory response 4
          leukotriene production involved in inflammatory response + 3
          prostaglandin production involved in inflammatory response 1
Path 2
Term Annotations click to browse term
  biological_process 20017
    response to stimulus 10569
      response to stress 4060
        defense response 1686
          inflammatory response 732
            production of molecular mediator involved in inflammatory response 87
              arachidonic acid metabolite production involved in inflammatory response 4
                leukotriene production involved in inflammatory response + 3
                prostaglandin production involved in inflammatory response 1
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.