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ONTOLOGY REPORT - ANNOTATIONS


Term:somatic diversification of immunoglobulin genes by N region addition
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Accession:GO:0002570 term browser browse the term
Definition:The addition of variable numbers of random nucleotides by terminal deoxytransferase in the N regions of heavy chain immunoglobulin genes. N regions are found at the V-D and D-J recombinational junctions.
Synonyms:exact_synonym: somatic diversification of antibody genes by N region addition


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  biological_process 19336
    immune system process 2611
      somatic diversification of immune receptors 80
        somatic diversification of immune receptors by N region addition 0
          somatic diversification of immunoglobulin genes by N region addition 0
Path 2
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  biological_process 19336
    cellular process 17240
      cellular metabolic process 10567
        cellular nitrogen compound metabolic process 6322
          nucleobase-containing compound metabolic process 5256
            nucleic acid metabolic process 4768
              DNA metabolic process 877
                DNA recombination 306
                  somatic cell DNA recombination 73
                    somatic diversification of immune receptors via germline recombination within a single locus 73
                      somatic recombination of immunoglobulin gene segments 60
                        somatic diversification of immunoglobulin genes by N region addition 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.