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ONTOLOGY REPORT - ANNOTATIONS


Term:platelet degranulation
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Accession:GO:0002576 term browser browse the term
Definition:The regulated exocytosis of secretory granules containing preformed mediators such as histamine and serotonin by a platelet.
Synonyms:exact_synonym: platelet exocytosis


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platelet degranulation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Blk BLK proto-oncogene, Src family tyrosine kinase IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr15:46,555,552...46,593,778
Ensembl chr15:46,555,188...46,593,653
JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase ISO
IBA
ISS
(MGI:MGI:5298337|PMID:20189992)
PMID:21873635
GO_REF:0000024
RGD
UniProt
PMID:20189992, PMID:21873635 GO_REF:0000024, MGI:MGI:5298337, RGD:13792537 NCBI chr 5:16,526,058...16,642,648
Ensembl chr 5:16,526,058...16,642,648
JBrowse link
G Plek pleckstrin ISO (PMID:7559487) RGD PMID:7559487 NCBI chr14:100,151,518...100,184,192
Ensembl chr14:100,151,210...100,217,913
JBrowse link
G Stxbp1 syntaxin binding protein 1 ISO (PMID:12773094) RGD PMID:12773094 NCBI chr 3:11,823,779...11,885,479
Ensembl chr 3:11,823,785...11,885,417
JBrowse link
protein secretion by platelet term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dmtn dematin actin binding protein ISO (MGI:MGI:5465511|PMID:23060452) RGD PMID:23060452 MGI:MGI:5465511 NCBI chr15:52,292,762...52,320,385
Ensembl chr15:52,292,765...52,320,385
JBrowse link
G Plek pleckstrin ISO (MGI:MGI:3844782|PMID:19190246) RGD PMID:19190246 MGI:MGI:3844782 NCBI chr14:100,151,518...100,184,192
Ensembl chr14:100,151,210...100,217,913
JBrowse link
serotonin secretion by platelet term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fcer1g Fc fragment of IgE receptor Ig ISO (MGI:MGI:87668|PMID:9171347) RGD PMID:9171347 MGI:MGI:87668 NCBI chr13:89,601,894...89,606,326
Ensembl chr13:89,601,896...89,606,326
JBrowse link
G P2rx1 purinergic receptor P2X 1 ISO MGI:MGI:2181608 (MGI:MGI:2671726|PMID:12913094) RGD PMID:12913094 MGI:MGI:2671726 NCBI chr10:59,566,268...59,581,328
Ensembl chr10:59,566,223...59,581,325
JBrowse link
G Syk spleen associated tyrosine kinase IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(MGI:MGI:87668|PMID:9171347)
Ensembl
UniProt
RGD
PMID:9171347 GO_REF:0000024, GO_REF:0000107, MGI:MGI:87668 NCBI chr17:12,614,311...12,669,568
Ensembl chr17:12,614,311...12,669,573
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20027
    cellular process 18798
      cellular localization 2966
        establishment of localization in cell 2177
          platelet degranulation 8
            histamine secretion by platelet 0
            protein secretion by platelet 2
            serotonin secretion by platelet 3
Path 2
Term Annotations click to browse term
  biological_process 20027
    localization 6496
      establishment of localization 4911
        transport 4759
          export from cell 1037
            secretion by cell 986
              exocytosis 427
                regulated exocytosis 293
                  platelet degranulation 8
                    histamine secretion by platelet 0
                    protein secretion by platelet 2
                    serotonin secretion by platelet 3
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.