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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of immunoglobulin production
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Accession:GO:0002638 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate, or extent of immunoglobulin production.
Synonyms:exact_synonym: down regulation of immunoglobulin production;   downregulation of immunoglobulin production
 narrow_synonym: inhibition of immunoglobulin production


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negative regulation of immunoglobulin production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fcgr2b Fc fragment of IgG receptor IIb JBrowse link 13 89,329,298 89,343,916 RGD:1624291
G Il13ra2 interleukin 13 receptor subunit alpha 2 JBrowse link X 118,443,955 118,514,716 RGD:1624291
RGD:1600115
G Prkdc protein kinase, DNA-activated, catalytic subunit JBrowse link 11 89,293,547 89,510,948 RGD:8696027
G Zpbp2 zona pellucida binding protein 2 JBrowse link 10 86,513,645 86,523,375 RGD:1600115
RGD:1624291
negative regulation of immunoglobulin secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd22 CD22 molecule JBrowse link 1 89,313,475 89,329,902 RGD:1624291
G Il33 interleukin 33 JBrowse link 1 248,112,611 248,147,030 RGD:1624291
RGD:1600115
G Siglec10 sialic acid binding Ig-like lectin 10 JBrowse link 1 98,512,663 98,521,736 RGD:1624291
G Tmbim6 transmembrane BAX inhibitor motif containing 6 JBrowse link 7 141,039,433 141,070,269 RGD:1624291
negative regulation of isotype switching term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Parp3 poly (ADP-ribose) polymerase family, member 3 JBrowse link 8 115,173,440 115,179,543 RGD:1624291
negative regulation of isotype switching to IgA isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Da2-19 uncharacterized LOC302729 JBrowse link X 48,196,789 48,213,506 RGD:1600115
G Thoc1 THO complex 1 JBrowse link 18 1,142,540 1,177,084 RGD:1624291
negative regulation of isotype switching to IgE isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bcl6 BCL6, transcription repressor JBrowse link 11 80,255,790 80,279,075 RGD:1624291
G Foxp3 forkhead box P3 JBrowse link X 15,753,175 15,768,648 RGD:1624291
G Ndfip1 Nedd4 family interacting protein 1 JBrowse link 18 31,574,759 31,625,286 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19439
    immune system process 2631
      production of molecular mediator of immune response 365
        immunoglobulin production 260
          negative regulation of immunoglobulin production 14
            negative regulation of immunoglobulin biosynthetic process 0
            negative regulation of immunoglobulin secretion 4
            negative regulation of isotype switching + 6
Path 2
Term Annotations click to browse term
  biological_process 19439
    biological regulation 13444
      regulation of biological process 12747
        regulation of immune system process 1444
          negative regulation of immune system process 472
            negative regulation of immune effector process 140
              negative regulation of production of molecular mediator of immune response 38
                negative regulation of immunoglobulin production 14
                  negative regulation of immunoglobulin biosynthetic process 0
                  negative regulation of immunoglobulin secretion 4
                  negative regulation of isotype switching + 6
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.