ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of leukocyte migration
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Accession:GO:0002686 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte migration.
Synonyms:exact_synonym: down regulation of leukocyte migration;   downregulation of leukocyte migration;   negative regulation of immune cell migration;   negative regulation of leucocyte migration
 narrow_synonym: inhibition of leukocyte migration


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negative regulation of leukocyte migration term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ada adenosine deaminase JBrowse link 3 160,115,840 160,139,947 RGD:1624291
RGD:1600115
G Adora1 adenosine A1 receptor JBrowse link 13 51,042,111 51,076,913 RGD:1624291
RGD:1600115
G Adtrp androgen-dependent TFPI-regulating protein JBrowse link 17 22,619,913 22,688,296 RGD:1624291
G Hoxa7 homeobox A7 JBrowse link 4 82,184,299 82,187,890 RGD:1624291
G Il33 interleukin 33 JBrowse link 1 248,112,611 248,147,030 RGD:1624291
RGD:1600115
G Rabgef1 RAB guanine nucleotide exchange factor 1 JBrowse link 12 29,960,132 30,004,727 RGD:1624291
RGD:1600115
negative regulation of cellular extravasation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abr ABR activator of RhoGEF and GTPase JBrowse link 10 64,565,121 64,657,079 RGD:1624291
RGD:1600115
G Bcr BCR activator of RhoGEF and GTPase JBrowse link 20 14,421,250 14,546,406 RGD:1624291
RGD:1600115
G Il27ra interleukin 27 receptor subunit alpha JBrowse link 19 25,151,835 25,163,995 RGD:1624291
negative regulation of dendritic cell chemotaxis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Slamf8 SLAM family member 8 JBrowse link 13 90,967,862 90,978,752 RGD:1624291
negative regulation of eosinophil extravasation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ptger4 prostaglandin E receptor 4 JBrowse link 2 54,951,625 54,966,470 RGD:1600115
RGD:1624291
negative regulation of eosinophil migration term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd300a Cd300a molecule JBrowse link 10 103,437,978 103,451,170 RGD:1624291
negative regulation of leukocyte chemotaxis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gpr18 G protein-coupled receptor 18 JBrowse link 15 108,323,157 108,326,907 RGD:1624291
RGD:1600115
G Grem1 gremlin 1, DAN family BMP antagonist JBrowse link 3 105,203,309 105,214,989 RGD:2303400
G Slit2 slit guidance ligand 2 JBrowse link 14 66,831,848 67,171,491 RGD:1624291
negative regulation of leukocyte tethering or rolling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ccl21 C-C motif chemokine ligand 21 JBrowse link 5 58,197,678 58,198,782 RGD:1624291
RGD:1600115
G Ccl25 C-C motif chemokine ligand 25 JBrowse link 12 2,429,492 2,438,928 RGD:1624291
G Ccl28 C-C motif chemokine ligand 28 JBrowse link 2 52,379,341 52,403,979 RGD:1624291
RGD:1600115
G Cxcl12 C-X-C motif chemokine ligand 12 JBrowse link 4 149,261,044 149,273,891 RGD:1624291
RGD:1600115
negative regulation of lymphocyte chemotaxis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Padi2 peptidyl arginine deiminase 2 JBrowse link 5 159,428,479 159,471,113 RGD:1600115
RGD:1624291
negative regulation of lymphocyte migration term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adtrp androgen-dependent TFPI-regulating protein JBrowse link 17 22,619,913 22,688,296 RGD:1600115
RGD:1624291
G Akt1 AKT serine/threonine kinase 1 JBrowse link 6 137,218,398 137,239,970 RGD:1600115
RGD:1624291
G Gcsam germinal center-associated, signaling and motility JBrowse link 11 60,168,938 60,180,191 RGD:1624291
RGD:1600115
G Mia3 MIA SH3 domain ER export factor 3 JBrowse link 13 101,727,434 101,770,127 RGD:1624291
G Wasl WASP like actin nucleation promoting factor JBrowse link 4 51,677,722 51,726,212 RGD:1624291
RGD:1600115
negative regulation of macrophage chemotaxis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G C5 complement C5 JBrowse link 3
3
14,049,993
14,206,466
14,113,931
14,229,141
RGD:1624291
RGD:1600115
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 JBrowse link 8 58,744,849 58,772,408 RGD:1624291
RGD:1600115
G Ddt D-dopachrome tautomerase JBrowse link 20 13,827,153 13,829,624 RGD:1624291
G Mif macrophage migration inhibitory factor JBrowse link 20 13,715,219 13,732,980 RGD:1624291
G Mmp28 matrix metallopeptidase 28 JBrowse link 10 70,660,691 70,681,672 RGD:1624291
G Slamf8 SLAM family member 8 JBrowse link 13 90,967,862 90,978,752 RGD:1624291
G Stap1 signal transducing adaptor family member 1 JBrowse link 14 23,575,400 23,604,984 RGD:1624291
RGD:1600115
negative regulation of macrophage migration term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd200 Cd200 molecule JBrowse link 11 60,371,617 60,398,450 RGD:13792521
G Cd200r1 CD200 receptor 1 JBrowse link 11 60,848,161 60,882,470 RGD:13792521
G Emilin1 elastin microfibril interfacer 1 JBrowse link 6 26,821,249 26,829,013 RGD:1600115
RGD:1624291
negative regulation of microglial cell migration term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Stap1 signal transducing adaptor family member 1 JBrowse link 14 23,575,400 23,604,984 RGD:1624291
RGD:1600115
negative regulation of monocyte chemotaxis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ccn3 cellular communication network factor 3 JBrowse link 7 94,375,134 94,382,154 RGD:1624291
RGD:1600115
G Dusp1 dual specificity phosphatase 1 JBrowse link 10 16,970,642 16,973,425 RGD:1600115
RGD:1624291
G Grem1 gremlin 1, DAN family BMP antagonist JBrowse link 3 105,203,309 105,214,989 RGD:2303400
G Nbl1 NBL1, DAN family BMP antagonist JBrowse link 5 157,524,569 157,535,701 RGD:1624291
RGD:1600115
G Slamf8 SLAM family member 8 JBrowse link 13 90,967,862 90,978,752 RGD:1624291
G Slit2 slit guidance ligand 2 JBrowse link 14 66,831,848 67,171,491 RGD:2303400
negative regulation of monocyte extravasation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Plcb1 phospholipase C beta 1 JBrowse link 3 127,721,244 128,419,565 RGD:1624291
RGD:1600115
negative regulation of mononuclear cell migration term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Slit2 slit guidance ligand 2 JBrowse link 14 66,831,848 67,171,491 RGD:1624291
RGD:1600115
negative regulation of natural killer cell chemotaxis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ccl2 C-C motif chemokine ligand 2 JBrowse link 10 69,412,065 69,413,863 RGD:1624291
G Klrk1 killer cell lectin like receptor K1 JBrowse link 4 163,392,652 163,403,735 RGD:1624291
RGD:1600115
negative regulation of neutrophil chemotaxis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G C5ar2 complement component 5a receptor 2 JBrowse link 1 78,165,155 78,183,426 RGD:1624291
RGD:1600115
G Slit2 slit guidance ligand 2 JBrowse link 14 66,831,848 67,171,491 RGD:1600115
RGD:1624291
negative regulation of neutrophil migration term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Slamf8 SLAM family member 8 JBrowse link 13 90,967,862 90,978,752 RGD:1624291
negative regulation of T cell extravasation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Il27ra interleukin 27 receptor subunit alpha JBrowse link 19 25,151,835 25,163,995 RGD:1600115
RGD:1624291
negative regulation of T cell migration term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Apod apolipoprotein D JBrowse link 11 72,705,204 72,726,263 RGD:1600115
RGD:1624291
G Cd200 Cd200 molecule JBrowse link 11 60,371,617 60,398,450 RGD:13792521
G Cd200r1 CD200 receptor 1 JBrowse link 11 60,848,161 60,882,470 RGD:13792521
G Lrch1 leucine rich repeats and calponin homology domain containing 1 JBrowse link 15 56,778,738 56,970,439 RGD:1624291
RGD:13792537
G Ripor2 RHO family interacting cell polarization regulator 2 JBrowse link 17 42,324,594 42,549,907 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17928
    negative regulation of biological process 5361
      negative regulation of immune system process 482
        negative regulation of leukocyte migration 43
          negative regulation of cellular extravasation + 9
          negative regulation of eosinophil migration + 2
          negative regulation of leukocyte chemotaxis + 17
          negative regulation of lymphocyte migration + 14
          negative regulation of macrophage migration + 10
          negative regulation of mononuclear cell migration + 7
          negative regulation of neutrophil migration + 3
Path 2
Term Annotations click to browse term
  biological_process 17928
    biological regulation 12623
      regulation of biological process 11965
        regulation of cellular process 11300
          regulation of cellular component movement 1053
            regulation of cell motility 967
              regulation of cell migration 917
                regulation of leukocyte migration 212
                  negative regulation of leukocyte migration 43
                    negative regulation of cellular extravasation + 9
                    negative regulation of eosinophil migration + 2
                    negative regulation of leukocyte chemotaxis + 17
                    negative regulation of lymphocyte migration + 14
                    negative regulation of macrophage migration + 10
                    negative regulation of mononuclear cell migration + 7
                    negative regulation of neutrophil migration + 3
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.