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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of production of molecular mediator of immune response
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Accession:GO:0002701 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate, or extent of the production of molecular mediator of immune response.
Synonyms:exact_synonym: down regulation of production of molecular mediator of immune response;   downregulation of production of molecular mediator of immune response
 narrow_synonym: inhibition of production of molecular mediator of immune response


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negative regulation of antibacterial peptide production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Spink5 serine peptidase inhibitor, Kazal type 5 JBrowse link 18 35,118,300 35,190,458 RGD:1624291
negative regulation of cytokine secretion involved in immune response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Angpt1 angiopoietin 1 JBrowse link 7 81,338,327 81,592,459 RGD:1624291
RGD:1600115
G Apoa1 apolipoprotein A1 JBrowse link 8 50,525,091 50,526,875 RGD:1624291
RGD:1600115
G Apoa2 apolipoprotein A2 JBrowse link 13 89,596,872 89,598,805 RGD:1624291
RGD:1600115
G Il10 interleukin 10 JBrowse link 13 47,738,933 47,743,392 RGD:1624291
RGD:1600115
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:1624291
negative regulation of dendritic cell cytokine production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Jak3 Janus kinase 3 JBrowse link 16 20,107,471 20,120,678 RGD:1624291
RGD:1600115
negative regulation of immunoglobulin production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fcgr2b Fc fragment of IgG receptor IIb JBrowse link 13 89,329,298 89,343,916 RGD:1624291
G Il13ra2 interleukin 13 receptor subunit alpha 2 JBrowse link X 118,443,955 118,514,716 RGD:1624291
RGD:1600115
G Prkdc protein kinase, DNA-activated, catalytic subunit JBrowse link 11 89,293,547 89,510,948 RGD:8696027
negative regulation of immunoglobulin secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd22 CD22 molecule JBrowse link 1 89,313,475 89,329,902 RGD:1624291
G Il33 interleukin 33 JBrowse link 1 248,112,611 248,147,030 RGD:1624291
RGD:1600115
G Siglec10 sialic acid binding Ig-like lectin 10 JBrowse link 1 98,512,663 98,521,736 RGD:1600115
RGD:1624291
G Tmbim6 transmembrane BAX inhibitor motif containing 6 JBrowse link 7 141,039,433 141,070,269 RGD:1624291
negative regulation of isotype switching term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Parp3 poly (ADP-ribose) polymerase family, member 3 JBrowse link 8 115,173,440 115,179,543 RGD:1600115
RGD:1624291
negative regulation of isotype switching to IgA isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Da2-19 uncharacterized LOC302729 JBrowse link X 48,196,789 48,213,506 RGD:1600115
G Thoc1 THO complex 1 JBrowse link 18 1,142,540 1,177,084 RGD:1624291
negative regulation of isotype switching to IgE isotypes term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bcl6 BCL6, transcription repressor JBrowse link 11 80,255,790 80,279,075 RGD:1624291
RGD:1600115
G Foxp3 forkhead box P3 JBrowse link X 15,753,175 15,768,648 RGD:1624291
RGD:1600115
G Ndfip1 Nedd4 family interacting protein 1 JBrowse link 18 31,574,759 31,625,286 RGD:1624291
RGD:1600115
negative regulation of macrophage cytokine production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cuedc2 CUE domain containing 2 JBrowse link 1 266,078,107 266,087,057 RGD:1624291
RGD:1600115
G Irak3 interleukin-1 receptor-associated kinase 3 JBrowse link 7 64,922,830 64,982,224 RGD:1624291
RGD:1600115
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:1624291
RGD:1600115
G Tgfb2 transforming growth factor, beta 2 JBrowse link 13 105,039,639 105,142,010 RGD:1624291
RGD:1600115
G Tgfb3 transforming growth factor, beta 3 JBrowse link 6 109,913,757 109,936,217 RGD:1624291
RGD:1600115
negative regulation of mast cell cytokine production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bcl6 BCL6, transcription repressor JBrowse link 11 80,255,790 80,279,075 RGD:1624291
RGD:1600115
G Hmox1 heme oxygenase 1 JBrowse link 19 14,508,634 14,515,455 RGD:1601626
negative regulation of natural killer cell cytokine production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd96 CD96 molecule JBrowse link 11 57,108,757 57,183,855 RGD:1624291
G RT1-CE5 RT1 class I, locus CE5 JBrowse link 20 4,892,702 4,896,993 RGD:1624291
negative regulation of plasmacytoid dendritic cell cytokine production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bst2 bone marrow stromal cell antigen 2 JBrowse link 16 19,938,781 19,942,353 RGD:1624291
RGD:1600115
negative regulation of T cell cytokine production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Foxp3 forkhead box P3 JBrowse link X 15,753,175 15,768,648 RGD:1624291
RGD:1600115
G Hfe homeostatic iron regulator JBrowse link 17 43,661,276 43,669,327 RGD:1624291
RGD:1600115
G RT1-CE5 RT1 class I, locus CE5 JBrowse link 20 4,892,702 4,896,993 RGD:1624291
G Slamf1 signaling lymphocytic activation molecule family member 1 JBrowse link 13 90,184,545 90,219,170 RGD:1624291
RGD:1600115
G Smad7 SMAD family member 7 JBrowse link 18 71,395,830 71,424,164 RGD:1600115
RGD:1624291
G Vsir V-set immunoregulatory receptor JBrowse link 20 29,897,543 29,923,381 RGD:1624291
G Xcl1 X-C motif chemokine ligand 1 JBrowse link 13 83,199,402 83,202,845 RGD:1624291
negative regulation of T-helper 2 cell cytokine production term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arg1 arginase 1 JBrowse link 1 21,525,421 21,537,872 RGD:1624291
RGD:1600115
G Ifnb1 interferon beta 1 JBrowse link 5 106,865,192 106,865,746 RGD:1624291
G Tbx21 T-box transcription factor 21 JBrowse link 10 85,032,799 85,049,331 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19312
    immune system process 2646
      production of molecular mediator of immune response 361
        negative regulation of production of molecular mediator of immune response 37
          negative regulation of antimicrobial peptide production + 1
          negative regulation of cytokine production involved in immune response + 25
          negative regulation of granzyme A production 0
          negative regulation of granzyme B production 0
          negative regulation of immunoglobulin production + 13
Path 2
Term Annotations click to browse term
  biological_process 19312
    biological regulation 13339
      regulation of biological process 12655
        regulation of immune system process 1478
          negative regulation of immune system process 489
            negative regulation of immune effector process 139
              negative regulation of production of molecular mediator of immune response 37
                negative regulation of antimicrobial peptide production + 1
                negative regulation of cytokine production involved in immune response + 25
                negative regulation of granzyme A production 0
                negative regulation of granzyme B production 0
                negative regulation of immunoglobulin production + 13
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.