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ONTOLOGY REPORT - ANNOTATIONS


Term:immune response-regulating signaling pathway
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Accession:GO:0002764 term browser browse the term
Definition:The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately leading to the activation, perpetuation, or inhibition of an immune response.
Synonyms:exact_synonym: immune response-regulating signalling pathway


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immune response-regulating signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ctsh cathepsin H JBrowse link 8 97,439,155 97,458,293 RGD:1600115
RGD:1624291
antigen receptor-mediated signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bcar1 BCAR1 scaffold protein, Cas family member JBrowse link 19 43,932,543 43,967,452 RGD:1624291
RGD:1600115
G Cd19 CD19 molecule JBrowse link 1 197,815,422 197,822,123 RGD:1624291
G Lax1 lymphocyte transmembrane adaptor 1 JBrowse link 13 50,164,563 50,175,119 RGD:1624291
RGD:13792537
G Sh2b2 SH2B adaptor protein 2 JBrowse link 12 23,471,477 23,501,043 RGD:1624291
RGD:13792537
B cell receptor apoptotic signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bax BCL2 associated X, apoptosis regulator JBrowse link 1 101,451,801 101,457,207 RGD:1624291
RGD:1600115
B cell receptor signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AABR07034739.1 Ig lambda-2 chain C region RGD:13792537
G AABR07065640.1 RGD:13792537
G AABR07065643.1 RGD:13792537
G AABR07065645.1 RGD:13792537
G AABR07065645.2 RGD:13792537
G AABR07065651.1 RGD:13792537
G AABR07065651.2 RGD:13792537
G AABR07065651.3 RGD:13792537
G AABR07065651.4 RGD:13792537
G AABR07065651.5 RGD:13792537
G AABR07065651.6 RGD:13792537
G AABR07065651.7 RGD:13792537
G AABR07065651.8 RGD:13792537
G AABR07065656.1 RGD:13792537
G AABR07065656.10 RGD:13792537
G AABR07065656.2 RGD:13792537
G AABR07065656.3 RGD:13792537
G AABR07065656.4 RGD:13792537
G AABR07065656.5 RGD:13792537
G AABR07065656.6 RGD:13792537
G AABR07065656.7 RGD:13792537
G AABR07065656.8 RGD:13792537
G AABR07065656.9 RGD:13792537
G AABR07065673.1 RGD:13792537
G AABR07065676.1 RGD:13792537
G AABR07065680.1 RGD:13792537
G AABR07065684.1 RGD:13792537
G AABR07065688.1 RGD:13792537
G AABR07065693.1 RGD:13792537
G AABR07065693.2 RGD:13792537
G AABR07065693.3 RGD:13792537
G AABR07065699.1 RGD:13792537
G AABR07065699.2 RGD:13792537
G AABR07065699.3 RGD:13792537
G AABR07065699.4 RGD:13792537
G AABR07065699.5 RGD:13792537
G AABR07065705.1 RGD:13792537
G AABR07065705.4 RGD:13792537
G AABR07065705.5 RGD:13792537
G AABR07065705.6 RGD:13792537
G AABR07065714.1 RGD:13792537
G AABR07065737.1 RGD:13792537
G AABR07065740.1 RGD:13792537
G AABR07065750.1 RGD:13792537
G AABR07065750.2 RGD:13792537
G AABR07065753.1 RGD:13792537
G AABR07065768.1 RGD:13792537
G AABR07065768.2 RGD:13792537
G AABR07065768.3 RGD:13792537
G AABR07065772.1 RGD:13792537
G AABR07065772.2 RGD:13792537
G AABR07065772.4 RGD:13792537
G AABR07065773.1 RGD:13792537
G AABR07065774.1 RGD:13792537
G AABR07065776.2 RGD:13792537
G AABR07065776.3 RGD:13792537
G AABR07065778.1 RGD:13792537
G AABR07065778.2 RGD:13792537
G AABR07065778.3 RGD:13792537
G AABR07065781.1 RGD:13792537
G AABR07065782.1 RGD:13792537
G AABR07065789.1 RGD:13792537
G AABR07065789.2 RGD:13792537
G AABR07065789.3 RGD:13792537
G AABR07065790.1 RGD:13792537
G AABR07065792.1 RGD:13792537
G AABR07065792.2 RGD:13792537
G AABR07065798.1 RGD:13792537
G AABR07065802.1 RGD:13792537
G AABR07065804.1 RGD:13792537
G AABR07065808.1 RGD:13792537
G AABR07065811.1 RGD:13792537
G AABR07065812.1 RGD:13792537
G AABR07065812.2 RGD:13792537
G AABR07065813.1 RGD:13792537
G AABR07065814.1 RGD:13792537
G AABR07065814.2 RGD:13792537
G AABR07065814.3 RGD:13792537
G AABR07065814.4 RGD:13792537
G AABR07065814.5 RGD:13792537
G AABR07065814.7 RGD:13792537
G AABR07065815.1 RGD:13792537
G AABR07065815.2 RGD:13792537
G AABR07065821.1 RGD:13792537
G AABR07065823.1 RGD:13792537
G AABR07065823.2 RGD:13792537
G AABR07065823.3 RGD:13792537
G AABR07065827.1 RGD:13792537
G AABR07065834.1 RGD:13792537
G AABR07065837.1 RGD:13792537
G AABR07065839.1 RGD:13792537
G AABR07065844.1 RGD:13792537
G AABR07065877.1 RGD:13792537
G AABR07065883.1 RGD:13792537
G AABR07065886.1 RGD:13792537
G AABR07065889.1 RGD:13792537
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase JBrowse link 3 10,041,820 10,145,076 RGD:1624291
G AC109737.1 RGD:13792537
G Bcar1 BCAR1 scaffold protein, Cas family member JBrowse link 19 43,932,543 43,967,452 RGD:1600115
RGD:1624291
G Bcl2 BCL2, apoptosis regulator JBrowse link 13 26,605,426 26,769,374 RGD:1600115
RGD:1624291
G Blk BLK proto-oncogene, Src family tyrosine kinase JBrowse link 15 46,555,552 46,593,778 RGD:1624291
G Blnk B-cell linker JBrowse link 1 260,187,023 260,254,490 RGD:1624291
G Bmx BMX non-receptor tyrosine kinase JBrowse link X 31,976,231 32,046,326 RGD:13792537
G Cd19 CD19 molecule JBrowse link 1 197,815,422 197,822,123 RGD:13792537
RGD:1624291
G Cd38 CD38 molecule JBrowse link 14 71,714,768 71,754,990 RGD:1624291
G Cd79a CD79a molecule JBrowse link 1 81,763,609 81,768,039 RGD:1624291
RGD:13792537
G Cd79al Cd79a molecule-like JBrowse link 9 16,793,811 16,795,994 RGD:13792537
G Cd79b CD79b molecule JBrowse link 10 94,497,445 94,500,591 RGD:1624291
RGD:13792537
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 JBrowse link 9 67,699,397 67,706,068 RGD:1624291
RGD:13792537
G IgG-2a gamma-2a immunoglobulin heavy chain RGD:13792537
G Igh-6 immunoglobulin heavy chain 6 RGD:13792537
G Ighe immunoglobulin heavy constant epsilon JBrowse link 6 138,066,728 138,068,606 RGD:13792537
G Ighg1 immunoglobulin heavy constant gamma 1 JBrowse link 6 139,140,572 139,784,388 RGD:13792537
G Ighm immunoglobulin heavy constant mu RGD:13792537
G Igkc immunoglobulin kappa constant RGD:13792537
G Igll1 immunoglobulin lambda-like polypeptide 1 JBrowse link 11 88,388,378 88,391,524 RGD:13792537
G Itk IL2-inducible T-cell kinase JBrowse link 10 31,431,820 31,493,413 RGD:13792537
G Klhl6 kelch-like family member 6 JBrowse link 11 84,745,958 84,785,315 RGD:1624291
G Lat2 linker for activation of T cells family, member 2 JBrowse link 12 25,114,099 25,128,381 RGD:1624291
RGD:1600115
G Lck LCK proto-oncogene, Src family tyrosine kinase JBrowse link 5 147,750,976 147,779,627 RGD:1624291
RGD:13792537
G Lime1 Lck interacting transmembrane adaptor 1 JBrowse link 3 176,881,881 176,888,230 RGD:1624291
RGD:13792537
G LOC100359530 rCG21044-like JBrowse link 6 138,930,894 138,931,525 RGD:13792537
G LOC100359684 mCG114411-like JBrowse link 6 140,406,777 140,407,357 RGD:13792537
G LOC100360344 hypothetical protein LOC100360344 JBrowse link 6 139,292,970 139,293,665 RGD:13792537
G LOC100360436 hypothetical LOC100360436 JBrowse link 6 139,345,463 139,346,007 RGD:13792537
G LOC100360761 rCG64219-like JBrowse link 6 140,979,689 140,980,243 RGD:13792537
G LOC100361105 Igh protein-like JBrowse link 6 141,146,691 141,147,268 RGD:13792537
G LOC100361706 lambda-chain C1-region-like JBrowse link 11 86,094,822 86,096,399 RGD:13792537
G LOC100361945 mCG129376-like JBrowse link 6 139,486,687 139,487,301 RGD:13792537
G LOC100365649 hypothetical LOC100365649 JBrowse link 6 138,743,974 138,744,542 RGD:13792537
G LOC100911906 uncharacterized LOC100911906 JBrowse link 6 138,954,101 138,954,839 RGD:13792537
G LOC362795 immunoglobulin G heavy chain JBrowse link 6 138,192,156 138,201,560 RGD:13792537
G LOC691815 Ig heavy chain V region PJ14-like JBrowse link 6 140,714,720 140,715,176 RGD:13792537
G Lyn LYN proto-oncogene, Src family tyrosine kinase JBrowse link 5 16,526,058 16,642,648 RGD:1624291
G Mapk1 mitogen activated protein kinase 1 JBrowse link 11 88,203,863 88,273,301 RGD:1624291
G Mef2c myocyte enhancer factor 2C JBrowse link 2 11,658,534 11,822,788 RGD:1600115
RGD:1624291
G Mnda myeloid cell nuclear differentiation antigen JBrowse link 13 92,073,664 92,091,335 RGD:1624291
G Ms4a1 membrane spanning 4-domains A1 JBrowse link 1 227,429,241 227,441,492 RGD:1624291
G Nckap1l NCK associated protein 1 like JBrowse link 7 145,068,239 145,113,507 RGD:1624291
RGD:1600115
G Nfam1 NFAT activating protein with ITAM motif 1 JBrowse link 7 123,856,718 123,893,790 RGD:1624291
G Nfatc2 nuclear factor of activated T-cells 2 JBrowse link 3 165,241,750 165,374,644 RGD:1624291
G Plcg2 phospholipase C, gamma 2 JBrowse link 19 50,039,410 50,173,543 RGD:1600115
RGD:1624291
G Plekha1 pleckstrin homology domain containing A1 JBrowse link 1 201,429,716 201,481,411 RGD:1624291
G Prkcb protein kinase C, beta JBrowse link 1 192,233,569 192,575,339 RGD:1600115
RGD:1624291
G Ptpn6 protein tyrosine phosphatase, non-receptor type 6 JBrowse link 4 157,239,141 157,263,890 RGD:1600115
RGD:1624291
G Ptprc protein tyrosine phosphatase, receptor type, C JBrowse link 13 55,061,561 55,174,150 RGD:1600115
RGD:1624291
G Rftn1 raftlin lipid raft linker 1 JBrowse link 9 12,740,885 12,942,358 RGD:1624291
G RGD1564318 similar to immunoglobulin light chain variable region RGD:13792537
G Sh2b2 SH2B adaptor protein 2 JBrowse link 12 23,471,477 23,501,043 RGD:1624291
G Syk spleen associated tyrosine kinase JBrowse link 17 12,614,311 12,669,568 RGD:1600115
RGD:13792537
RGD:1624291
G Tec tec protein tyrosine kinase JBrowse link 14 37,918,884 38,027,953 RGD:1624291
RGD:13792537
G Vav3 vav guanine nucleotide exchange factor 3 JBrowse link 2 212,247,061 212,585,818 RGD:1624291
cell surface pattern recognition receptor signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fcna ficolin A JBrowse link 3 2,850,006 2,853,230 RGD:1600115
G Fcnb ficolin B JBrowse link 3 6,617,816 6,626,193 RGD:1624291
G Ffar2 free fatty acid receptor 2 JBrowse link 1 89,268,197 89,271,942 RGD:1624291
RGD:1600115
G Tlr2 toll-like receptor 2 JBrowse link 2 182,840,171 182,846,061 RGD:1624291
complement component C5a signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G C5ar1 complement C5a receptor 1 JBrowse link 1 78,186,777 78,195,132 RGD:1624291
G C5ar2 complement component 5a receptor 2 JBrowse link 1 78,165,155 78,183,426 RGD:1600115
complement receptor mediated signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G C3ar1 complement C3a receptor 1 JBrowse link 4 155,681,767 155,691,240 RGD:1600115
RGD:13792537
RGD:1624291
G C5ar1 complement C5a receptor 1 JBrowse link 1 78,186,777 78,195,132 RGD:13792537
G C5ar2 complement component 5a receptor 2 JBrowse link 1 78,165,155 78,183,426 RGD:13792537
G Cmklr1 chemerin chemokine-like receptor 1 JBrowse link 12 48,743,556 48,796,582 RGD:13792537
G Cr2 complement C3d receptor 2 JBrowse link 13 113,890,274 113,927,824 RGD:1600115
G Fpr-rs3 formyl peptide receptor, related sequence 3 JBrowse link 1 59,902,308 59,903,339 RGD:13792537
G Fpr-rs4 formyl peptide receptor, related sequence 4 JBrowse link 1 86,073,435 86,074,406 RGD:13792537
G Fpr-rs6 formyl peptide receptor, related sequence 6 JBrowse link 1 86,262,503 86,263,534 RGD:13792537
G Fpr1 formyl peptide receptor 1 JBrowse link 1 59,759,025 59,767,258 RGD:13792537
G Fpr2 formyl peptide receptor 2 JBrowse link 1 59,800,558 59,809,507 RGD:13792537
G Fpr3 formyl peptide receptor 3 JBrowse link 1 116,152,526 116,161,873 RGD:13792537
G Gpld1 glycosylphosphatidylinositol specific phospholipase D1 JBrowse link 17 42,085,027 42,131,344 RGD:1600115
RGD:1624291
G Gpr33 G protein-coupled receptor 33 JBrowse link 6 72,804,843 72,805,848 RGD:13792537
Fc receptor mediated inhibitory signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lilrb2 leukocyte immunoglobulin like receptor B2 JBrowse link 1 63,734,135 63,741,986 RGD:1624291
G Lyn LYN proto-oncogene, Src family tyrosine kinase JBrowse link 5 16,526,058 16,642,648 RGD:1624291
RGD:1600115
Fc receptor mediated stimulatory signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Blk BLK proto-oncogene, Src family tyrosine kinase JBrowse link 15 46,555,552 46,593,778 RGD:13792537
G Fcer1g Fc fragment of IgE receptor Ig JBrowse link 13 89,601,894 89,606,326 RGD:1624291
RGD:13792537
G Lyn LYN proto-oncogene, Src family tyrosine kinase JBrowse link 5 16,526,058 16,642,648 RGD:1624291
RGD:13792537
RGD:1600115
Fc receptor signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fcar Fc fragment of IgA receptor JBrowse link 1 73,230,392 73,263,462 RGD:1624291
G Kit KIT proto-oncogene receptor tyrosine kinase JBrowse link 14 35,072,131 35,149,638 RGD:1624291
G Pigr polymeric immunoglobulin receptor JBrowse link 13 47,564,176 47,592,093 RGD:1600115
RGD:1624291
Fc-epsilon receptor signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fcer1a Fc fragment of IgE receptor Ia JBrowse link 13 91,727,253 91,737,106 RGD:1600115
G Fcer1g Fc fragment of IgE receptor Ig JBrowse link 13 89,601,894 89,606,326 RGD:1624291
G Fcgr3a Fc fragment of IgG receptor IIIa JBrowse link 13 89,385,775 89,396,047 RGD:1600115
G Fer FER tyrosine kinase JBrowse link 9 111,557,804 111,868,583 RGD:1600115
RGD:13792537
RGD:1624291
G Ms4a2 membrane spanning 4-domains A2 JBrowse link 1 227,957,363 227,965,312 RGD:1600115
Fc-gamma receptor signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Clec4d C-type lectin domain family 4, member D JBrowse link 4 156,253,084 156,264,766 RGD:1624291
RGD:1600115
G Clec4e C-type lectin domain family 4, member E JBrowse link 4 156,271,087 156,276,243 RGD:1624291
RGD:1600115
G Fcer1g Fc fragment of IgE receptor Ig JBrowse link 13 89,601,894 89,606,326 RGD:1624291
RGD:13792537
G Fcgr1a Fc fragment of IgG receptor Ia JBrowse link 2 198,430,536 198,439,453 RGD:1600115
G Fcgr2a Fc fragment of IgG receptor IIa JBrowse link 13 91,146,878 91,163,691 RGD:1600115
G Fcgr3a Fc fragment of IgG receptor IIIa JBrowse link 13 89,385,775 89,396,047 RGD:1600115
G Fcgrt Fc fragment of IgG receptor and transporter JBrowse link 1 101,086,872 101,096,159 RGD:1600115
G LOC100911825 low affinity immunoglobulin gamma Fc region receptor III-like JBrowse link 13 91,219,838 91,237,274 RGD:1600115
G LOC108348047 low affinity immunoglobulin gamma Fc region receptor III JBrowse link 13 89,420,835 89,440,644 RGD:1600115
G LOC498276 Fc gamma receptor II beta JBrowse link 13 91,168,972 91,181,937 RGD:1600115
G Oscar osteoclast associated Ig-like receptor JBrowse link 1 64,182,174 64,188,658 RGD:1624291
Fc-gamma receptor signaling pathway involved in phagocytosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fcgr2b Fc fragment of IgG receptor IIb JBrowse link 13 89,329,298 89,343,916 RGD:1624291
G Myo1g myosin IG JBrowse link 14 86,781,243 86,796,393 RGD:1624291
immune response-activating cell surface receptor signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bag6 BAG cochaperone 6 JBrowse link 20 5,124,512 5,138,084 RGD:1624291
G Micb MHC class I polypeptide-related sequence B JBrowse link 1 79,754,587 79,772,092 RGD:1624291
G Ncr3 natural cytotoxicity triggering receptor 3 JBrowse link 20 5,170,169 5,175,773 RGD:1600115
RGD:13792537
RGD:1624291
immune response-activating signal transduction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Zc3h12a zinc finger CCCH type containing 12A JBrowse link 5 143,111,342 143,120,131 RGD:1600115
RGD:1624291
immune response-inhibiting cell surface receptor signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lilrb2 leukocyte immunoglobulin like receptor B2 JBrowse link 1 63,734,135 63,741,986 RGD:1624291
immune response-inhibiting signal transduction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd33 CD33 molecule JBrowse link 1 98,388,811 98,403,539 RGD:1624291
G Il20rb interleukin 20 receptor subunit beta JBrowse link 8 108,745,906 108,778,561 RGD:1624291
immune response-regulating cell surface receptor signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Btla B and T lymphocyte associated JBrowse link 11 60,523,692 60,547,234 RGD:1624291
RGD:13792537
RGD:1600115
G Cd40 CD40 molecule JBrowse link 3 161,519,789 161,534,943 RGD:1624291
RGD:13792537
G Fpr2 formyl peptide receptor 2 JBrowse link 1 59,800,558 59,809,507 RGD:1624291
G Lyn LYN proto-oncogene, Src family tyrosine kinase JBrowse link 5 16,526,058 16,642,648 RGD:1624291
RGD:1600115
G Vav1 vav guanine nucleotide exchange factor 1 JBrowse link 9 9,617,551 9,675,167 RGD:2306006
innate immune response-activating signal transduction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Tlr4 toll-like receptor 4 JBrowse link 5 82,587,424 82,601,056 RGD:2312509
natural killer cell inhibitory signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Clec12b C-type lectin domain family 12, member B JBrowse link 4 163,140,883 163,157,996 RGD:1624291
RGD:13792537
negative regulation of B cell receptor signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd22 CD22 molecule JBrowse link 1 89,313,475 89,329,902 RGD:1624291
RGD:13792537
G Cd300a Cd300a molecule JBrowse link 10 103,437,978 103,451,170 RGD:1624291
G Fcgr2b Fc fragment of IgG receptor IIb JBrowse link 13 89,329,298 89,343,916 RGD:1624291
G Fcrl5 Fc receptor-like 5 JBrowse link 2 186,776,466 186,797,900 RGD:1624291
G Gps2 G protein pathway suppressor 2 JBrowse link 10 56,524,327 56,527,447 RGD:1624291
G Lpxn leupaxin JBrowse link 1 229,642,437 229,674,129 RGD:1624291
RGD:13792537
G Plcl2 phospholipase C-like 2 JBrowse link 9 1,782,536 1,984,654 RGD:1624291
negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Appl1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 JBrowse link 16 2,560,103 2,602,035 RGD:1624291
G Cd47 Cd47 molecule JBrowse link 11 53,511,485 53,575,754 RGD:13792533
negative regulation of T cell receptor signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AABR07035561.2 RGD:13792537
G Btn2a2 butyrophilin, subfamily 2, member A2 JBrowse link 17 43,867,243 43,878,734 RGD:1624291
G Btnl2 butyrophilin-like 2 JBrowse link 20 4,140,184 4,156,365 RGD:1624291
RGD:1600115
G Cblb Cbl proto-oncogene B JBrowse link 11 51,037,383 51,202,761 RGD:1624291
G Cd160 CD160 molecule JBrowse link 2 198,933,681 198,965,380 RGD:1624291
G Ceacam1 CEA cell adhesion molecule 1 JBrowse link 1 82,327,955 82,344,345 RGD:1624291
RGD:1600115
G Dgkz diacylglycerol kinase zeta JBrowse link 3 80,844,002 80,886,487 RGD:1600115
RGD:1624291
G Dusp22 dual specificity phosphatase 22 JBrowse link 17 34,986,589 35,037,297 RGD:1624291
G Dusp3 dual specificity phosphatase 3 JBrowse link 10 89,904,578 89,918,296 RGD:1624291
RGD:13792537
G Elf1 E74 like ETS transcription factor 1 JBrowse link 15 61,772,544 61,868,442 RGD:1624291
G Ezr ezrin JBrowse link 1 47,287,872 47,331,412 RGD:1624291
G Gbp1 guanylate binding protein 1 JBrowse link 2 248,343,334 248,423,402 RGD:1624291
RGD:1600115
G Lgals3 galectin 3 JBrowse link 15 24,153,602 24,165,537 RGD:1624291
G Lilrb4 leukocyte immunoglobulin like receptor B4 JBrowse link 1 73,393,854 73,399,448 RGD:1624291
G Pawr pro-apoptotic WT1 regulator JBrowse link 7 51,273,764 51,353,700 RGD:1624291
RGD:1600115
G Phpt1 phosphohistidine phosphatase 1 JBrowse link 3 2,797,037 2,798,436 RGD:1624291
G Prnp prion protein JBrowse link 3 124,515,917 124,531,320 RGD:1624291
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 JBrowse link 18 63,415,298 63,489,240 RGD:1624291
RGD:1600115
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 JBrowse link 2 206,342,066 206,390,348 RGD:1624291
G Ptpn6 protein tyrosine phosphatase, non-receptor type 6 JBrowse link 4 157,239,141 157,263,890 RGD:1624291
RGD:1600115
G Ptprj protein tyrosine phosphatase, receptor type, J JBrowse link 3 79,233,519 79,390,956 RGD:1624291
G Pvrig PVR related immunoglobulin domain containing JBrowse link 12 19,679,671 19,681,861 RGD:1624291
G Sh2d1a SH2 domain containing 1A JBrowse link X 128,897,053 128,925,408 RGD:1624291
G Sla2 Src-like-adaptor 2 JBrowse link 3 152,942,838 153,004,047 RGD:1624291
G Thy1 Thy-1 cell surface antigen JBrowse link 8 48,382,121 48,387,271 RGD:1624291
RGD:1600115
G Ubash3a ubiquitin associated and SH3 domain containing, A JBrowse link 20 9,941,102 9,986,012 RGD:1624291
RGD:13792537
positive regulation of antigen receptor-mediated signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ptprc protein tyrosine phosphatase, receptor type, C JBrowse link 13 55,061,561 55,174,150 RGD:1624291
RGD:1600115
positive regulation of B cell receptor signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd81 Cd81 molecule JBrowse link 1 216,237,663 216,253,460 RGD:1600115
RGD:1624291
G Cmtm3 CKLF-like MARVEL transmembrane domain containing 3 JBrowse link 19 830,874 838,528 RGD:1624291
G Foxp1 forkhead box P1 JBrowse link 4 131,362,178 131,963,466 RGD:1624291
G Nfam1 NFAT activating protein with ITAM motif 1 JBrowse link 7 123,856,718 123,893,790 RGD:1624291
G Prkcb protein kinase C, beta JBrowse link 1 192,233,569 192,575,339 RGD:1600115
RGD:1624291
G Prkch protein kinase C, eta JBrowse link 6 96,479,243 96,677,368 RGD:1624291
RGD:1600115
G Slc39a10 solute carrier family 39 member 10 JBrowse link 9 59,947,562 60,070,549 RGD:1624291
RGD:13792537
G Stap1 signal transducing adaptor family member 1 JBrowse link 14 23,575,400 23,604,984 RGD:1624291
positive regulation of Fc receptor mediated stimulatory signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AABR07032888.1 RGD:13792537
G Cd226 CD226 molecule JBrowse link 18 86,299,392 86,394,772 RGD:1624291
RGD:13792537
G Lyn LYN proto-oncogene, Src family tyrosine kinase JBrowse link 5 16,526,058 16,642,648 RGD:1578516
positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Appl2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 JBrowse link 7 26,256,179 26,306,128 RGD:1624291
G Ptprc protein tyrosine phosphatase, receptor type, C JBrowse link 13 55,061,561 55,174,150 RGD:1624291
G Ptprj protein tyrosine phosphatase, receptor type, J JBrowse link 3 79,233,519 79,390,956 RGD:1624291
G Rap1a RAP1A, member of RAS oncogene family JBrowse link 2 208,193,950 208,215,186 RGD:9835043
G Rapgef1 Rap guanine nucleotide exchange factor 1 JBrowse link 3 8,189,594 8,307,077 RGD:9835043
positive regulation of mast cell activation by Fc-epsilon receptor signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 JBrowse link 5 63,781,801 63,822,890 RGD:1624291
RGD:1600115
positive regulation of T cell receptor signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AABR07032888.1 RGD:13792537
G Ada adenosine deaminase JBrowse link 3 160,115,840 160,139,947 RGD:1624291
G Card11 caspase recruitment domain family, member 11 JBrowse link 12 15,700,600 15,844,512 RGD:1624291
G Ccr7 C-C motif chemokine receptor 7 JBrowse link 10 87,057,335 87,067,444 RGD:1624291
G Cd226 CD226 molecule JBrowse link 18 86,299,392 86,394,772 RGD:1624291
RGD:13792537
G Cd81 Cd81 molecule JBrowse link 1 216,237,663 216,253,460 RGD:1600115
RGD:1624291
G Cyld CYLD lysine 63 deubiquitinase JBrowse link 19 19,264,984 19,323,817 RGD:1624291
RGD:1600115
G Kcnn4 potassium calcium-activated channel subfamily N member 4 JBrowse link 1 81,227,855 81,245,986 RGD:1624291
RGD:1600115
G Nectin2 nectin cell adhesion molecule 2 JBrowse link 1 80,631,449 80,666,617 RGD:1624291
RGD:13792537
G Prkd2 protein kinase D2 JBrowse link 1 78,767,911 78,796,223 RGD:1624291
RGD:1600115
G Rab29 RAB29, member RAS oncogene family JBrowse link 13 48,644,575 48,650,229 RGD:1624291
G Rela RELA proto-oncogene, NF-kB subunit JBrowse link 1 220,992,770 221,003,249 RGD:1624291
G Rps3 ribosomal protein S3 JBrowse link 1 164,435,868 164,441,167 RGD:1624291
G Trat1 T cell receptor associated transmembrane adaptor 1 JBrowse link 11 54,619,169 54,661,284 RGD:1624291
regulation of B cell receptor signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Blk BLK proto-oncogene, Src family tyrosine kinase JBrowse link 15 46,555,552 46,593,778 RGD:13792537
G Cd19 CD19 molecule JBrowse link 1 197,815,422 197,822,123 RGD:1624291
G Gcsam germinal center-associated, signaling and motility JBrowse link 11 60,168,938 60,180,191 RGD:1624291
G Lyn LYN proto-oncogene, Src family tyrosine kinase JBrowse link 5 16,526,058 16,642,648 RGD:1624291
RGD:13792537
RGD:1600115
regulation of Fc receptor mediated stimulatory signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Csk C-terminal Src kinase JBrowse link 8 62,405,714 62,424,707 RGD:2303720
RGD:13792537
G Plscr1 phospholipid scramblase 1 JBrowse link 8 99,625,523 99,645,882 RGD:2303650
G Rabgef1 RAB guanine nucleotide exchange factor 1 JBrowse link 12 29,960,132 30,004,727 RGD:1624291
regulation of Fc-gamma receptor signaling pathway involved in phagocytosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fcgr2a Fc fragment of IgG receptor IIa JBrowse link 13 91,146,878 91,163,691 RGD:11041001
RGD:2293335
regulation of T cell receptor signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bcl10 BCL10, immune signaling adaptor JBrowse link 2 251,805,392 251,814,957 RGD:1624291
G Cacna1f calcium voltage-gated channel subunit alpha1 F JBrowse link X 15,712,709 15,741,135 RGD:1600115
G Cd300a Cd300a molecule JBrowse link 10 103,437,978 103,451,170 RGD:1624291
G Lck LCK proto-oncogene, Src family tyrosine kinase JBrowse link 5 147,750,976 147,779,627 RGD:1624291
G Malt1 MALT1 paracaspase JBrowse link 18 61,108,712 61,162,446 RGD:1624291
G Rc3h1 ring finger and CCCH-type domains 1 JBrowse link 13 78,723,028 78,794,663 RGD:1624291
stimulatory C-type lectin receptor signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Klre1 killer cell lectin-like receptor, family E, member 1 JBrowse link 4 163,346,684 163,355,050 RGD:1600115
G Klrk1 killer cell lectin like receptor K1 JBrowse link 4 163,392,652 163,403,735 RGD:1624291
T cell receptor signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AABR07049499.1 RGD:13792537
G AABR07049648.1 RGD:13792537
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase JBrowse link 3 10,041,820 10,145,076 RGD:1624291
G Bcl10 BCL10, immune signaling adaptor JBrowse link 2 251,805,392 251,814,957 RGD:1624291
RGD:1600115
G Braf B-Raf proto-oncogene, serine/threonine kinase JBrowse link 4 67,389,331 67,520,549 RGD:1624291
G Btn1a1 butyrophilin, subfamily 1, member A1 JBrowse link 17 43,899,155 43,909,042 RGD:13792537
G Btn2a2 butyrophilin, subfamily 2, member A2 JBrowse link 17 43,867,243 43,878,734 RGD:13792537
G Btnl10 butyrophilin like 10 JBrowse link 10 45,257,946 45,266,233 RGD:13792537
G Btnl2 butyrophilin-like 2 JBrowse link 20 4,140,184 4,156,365 RGD:13792537
G Btnl3 butyrophilin-like 3 JBrowse link 20 4,156,858 4,171,887 RGD:13792537
G Btnl5 butyrophilin-like 5 JBrowse link 20 2,723,576 2,733,181 RGD:13792537
G Btnl7 butyrophilin-like 7 JBrowse link 20 2,757,008 2,769,215 RGD:13792537
G Btnl8 butyrophilin-like 8 JBrowse link 20 2,845,720 2,863,449 RGD:13792537
G Btnl9 butyrophilin-like 9 JBrowse link 10 34,424,830 34,443,749 RGD:13792537
G Cacnb3 calcium voltage-gated channel auxiliary subunit beta 3 JBrowse link 7 140,311,120 140,324,902 RGD:1624291
G Cacnb4 calcium voltage-gated channel auxiliary subunit beta 4 JBrowse link 3 37,950,846 38,211,478 RGD:1624291
G Carmil2 capping protein regulator and myosin 1 linker 2 JBrowse link 19 37,652,383 37,665,333 RGD:1624291
G Cblb Cbl proto-oncogene B JBrowse link 11 51,037,383 51,202,761 RGD:1624291
G Cd247 Cd247 molecule JBrowse link 13 83,996,045 84,071,408 RGD:1624291
RGD:13792537
G Cd276 Cd276 molecule JBrowse link 8 63,312,060 63,350,411 RGD:13792537
G Cd28 Cd28 molecule JBrowse link 9 67,546,408 67,573,858 RGD:1624291
RGD:13792537
RGD:1600115
G Cd3e CD3e molecule JBrowse link 8 49,297,604 49,309,370 RGD:1624291
G Crkl CRK like proto-oncogene, adaptor protein JBrowse link 11 87,338,606 87,356,644 RGD:1624291
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 JBrowse link 9 67,699,397 67,706,068 RGD:13792537
G Dennd1b DENN domain containing 1B JBrowse link 13 56,015,813 56,242,041 RGD:1624291
RGD:13792537
G Eif2b1 eukaryotic translation initiation factor 2B subunit alpha JBrowse link 12 37,444,136 37,452,391 RGD:1600115
RGD:1624291
G Eif2b2 eukaryotic translation initiation factor 2B subunit beta JBrowse link 6 109,044,830 109,051,254 RGD:1600115
RGD:1624291
G Eif2b3 eukaryotic translation initiation factor 2B subunit gamma JBrowse link 5 135,882,946 135,949,276 RGD:1600115
RGD:1624291
G Eif2b4 eukaryotic translation initiation factor 2B subunit delta JBrowse link 6 26,546,917 26,552,474 RGD:1600115
RGD:1624291
G Eif2b5 eukaryotic translation initiation factor 2B subunit epsilon JBrowse link 11 84,080,273 84,090,259 RGD:1600115
RGD:1624291
G Ermap erythroblast membrane associated protein (Scianna blood group) JBrowse link 5 138,227,168 138,240,509 RGD:13792537
G Foxp3 forkhead box P3 JBrowse link X 15,753,175 15,768,648 RGD:1624291
G Fyb1 FYN binding protein 1 JBrowse link 2 55,834,904 55,983,805 RGD:13792537
G Fyb2 FYN binding protein 2 JBrowse link 5 124,442,386 124,561,766 RGD:1624291
G Fyn FYN proto-oncogene, Src family tyrosine kinase JBrowse link 20 44,436,354 44,630,316 RGD:1624291
RGD:13792537
G Gata3 GATA binding protein 3 JBrowse link 17 72,419,752 72,452,043 RGD:1624291
RGD:1600115
G Hras HRas proto-oncogene, GTPase JBrowse link 1 214,178,404 214,181,841 RGD:1624291
G Icoslg inducible T-cell co-stimulator ligand JBrowse link 20 11,330,000 11,340,307 RGD:13792537
G Ifng interferon gamma JBrowse link 7 61,337,383 61,341,419 RGD:1624291
G Itk IL2-inducible T-cell kinase JBrowse link 10 31,431,820 31,493,413 RGD:1624291
RGD:13792537
G Khdrbs1 KH RNA binding domain containing, signal transduction associated 1 JBrowse link 5 147,927,145 147,953,093 RGD:1624291
G Lcp2 lymphocyte cytosolic protein 2 JBrowse link 10 18,996,523 19,043,289 RGD:1624291
G Lime1 Lck interacting transmembrane adaptor 1 JBrowse link 3 176,881,881 176,888,230 RGD:1600115
G LOC100364500 RT1 class I, locus CE11-like JBrowse link 20 2,704,153 2,707,111 RGD:1624291
G LOC100911938 butyrophilin subfamily 3 member A3-like JBrowse link 20 2,813,330 2,825,537 RGD:13792537
G LOC100911983 butyrophilin subfamily 3 member A3-like JBrowse link 20 2,909,473 2,921,680 RGD:13792537
G LOC100912021 butyrophilin-like protein 1-like JBrowse link 20 2,937,876 2,939,080 RGD:13792537
G LOC689599 hypothetical protein LOC689599 JBrowse link 9 114,748,302 114,786,017 RGD:13792537
G Malt1 MALT1 paracaspase JBrowse link 18 61,108,712 61,162,446 RGD:1624291
RGD:13792537
G Mapk1 mitogen activated protein kinase 1 JBrowse link 11 88,203,863 88,273,301 RGD:1624291
G Mog myelin oligodendrocyte glycoprotein JBrowse link 20 2,003,871 2,014,284 RGD:13792537
G Nfkbid NFKB inhibitor delta JBrowse link 1 88,883,816 88,892,543 RGD:1624291
G Nfkbiz NFKB inhibitor zeta JBrowse link 11 47,243,342 47,271,487 RGD:1624291
G Nras NRAS proto-oncogene, GTPase JBrowse link 2 205,553,119 205,563,716 RGD:1624291
G Pde4b phosphodiesterase 4B JBrowse link 5 121,759,236 122,136,814 RGD:1624291
RGD:1600115
G Pde4d phosphodiesterase 4D JBrowse link 2 40,219,999 41,468,551 RGD:1624291
RGD:1600115
G Plcg1 phospholipase C, gamma 1 JBrowse link 3 156,727,642 156,758,307 RGD:1624291
RGD:1600115
G Plcg2 phospholipase C, gamma 2 JBrowse link 19 50,039,410 50,173,543 RGD:1624291
RGD:1600115
G Pram1 PML-RARA regulated adaptor molecule 1 JBrowse link 7 18,507,878 18,516,321 RGD:13792537
G Prkd2 protein kinase D2 JBrowse link 1 78,767,911 78,796,223 RGD:1624291
G Psen1 presenilin 1 JBrowse link 6 107,169,514 107,221,000 RGD:1624291
G Psen2 presenilin 2 JBrowse link 13 98,513,600 98,539,347 RGD:1624291
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 JBrowse link 2 206,342,066 206,390,348 RGD:1624291
RGD:13792537
G Ptprc protein tyrosine phosphatase, receptor type, C JBrowse link 13 55,061,561 55,174,150 RGD:1624291
RGD:1358565
RGD:1600115
G Rbck1 RANBP2-type and C3HC4-type zinc finger containing 1 JBrowse link 3 147,793,014 147,809,941 RGD:1600115
RGD:1624291
G Rc3h1 ring finger and CCCH-type domains 1 JBrowse link 13 78,723,028 78,794,663 RGD:1624291
G Rc3h2 ring finger and CCCH-type domains 2 JBrowse link 3 21,621,976 21,676,789 RGD:1624291
G Rftn1 raftlin lipid raft linker 1 JBrowse link 9 12,740,885 12,942,358 RGD:1624291
G RGD1624210 similar to butyrophilin-like 7 JBrowse link 20 4,269,526 4,283,089 RGD:13792537
G Ripk2 receptor-interacting serine-threonine kinase 2 JBrowse link 5 29,838,713 29,870,390 RGD:1624291
G Rnf31 ring finger protein 31 JBrowse link 15 34,270,037 34,282,385 RGD:1624291
G Shb SH2 domain containing adaptor protein B JBrowse link 5 60,970,650 61,077,881 RGD:1624291
G Skap1 src kinase associated phosphoprotein 1 JBrowse link 10 84,309,379 84,619,051 RGD:1624291
G Skint1 selection and upkeep of intraepithelial T cells 1 JBrowse link 5 131,915,266 131,944,842 RGD:13792537
G Skint10 selection and upkeep of intraepithelial T cells 10 JBrowse link 5 133,048,273 133,067,278 RGD:13792537
G Skint8 selection and upkeep of intraepithelial T cells 8 JBrowse link 5 131,867,780 131,902,258 RGD:13792537
G Spn sialophorin JBrowse link 1 198,572,999 198,585,664 RGD:1358565
G Sppl3 signal peptide peptidase like 3 JBrowse link 12 47,276,485 47,360,552 RGD:1624291
G Stk11 serine/threonine kinase 11 JBrowse link 7 12,440,751 12,457,513 RGD:1624291
RGD:1600115
G Stoml2 stomatin like 2 JBrowse link 5 58,472,561 58,476,158 RGD:1624291
RGD:1600115
G Tec tec protein tyrosine kinase JBrowse link 14 37,918,884 38,027,953 RGD:13792537
G Themis thymocyte selection associated JBrowse link 1 17,152,973 17,378,225 RGD:1624291
RGD:13792537
G Themis2 thymocyte selection associated family member 2 JBrowse link 5 150,971,795 150,986,596 RGD:1624291
RGD:13792537
G Thy1 Thy-1 cell surface antigen JBrowse link 8 48,382,121 48,387,271 RGD:8554466
RGD:13792537
G Tnfrsf21 TNF receptor superfamily member 21 JBrowse link 9 20,546,159 20,621,051 RGD:1624291
RGD:1600115
G Traf6 TNF receptor associated factor 6 JBrowse link 3 91,252,829 91,271,607 RGD:1624291
G Txk TXK tyrosine kinase JBrowse link 14 38,029,809 38,085,822 RGD:1624291
RGD:13792537
G Ube2n ubiquitin-conjugating enzyme E2N JBrowse link 7 36,610,147 36,640,190 RGD:1624291
G Vtcn1 V-set domain containing T cell activation inhibitor 1 JBrowse link 2 203,200,435 203,274,264 RGD:13792537
G Wnk1 WNK lysine deficient protein kinase 1 JBrowse link 4 152,452,211 152,578,469 RGD:1624291
G Zap70 zeta chain of T cell receptor associated protein kinase 70 JBrowse link 9 43,331,149 43,353,097 RGD:1624291
G Zc3h12a zinc finger CCCH type containing 12A JBrowse link 5 143,111,342 143,120,131 RGD:1600115
RGD:1624291
G Zfp683 zinc finger protein 683 JBrowse link 5 152,280,982 152,288,208 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19858
    signaling 7553
      signal transduction 6968
        immune response-regulating signaling pathway 343
          immune response-activating signal transduction + 320
          immune response-inhibiting signal transduction + 5
          immune response-regulating cell surface receptor signaling pathway + 339
Path 2
Term Annotations click to browse term
  biological_process 19858
    biological regulation 13636
      regulation of biological process 12959
        regulation of response to stimulus 4066
          regulation of immune response 863
            immune response-regulating signaling pathway 343
              immune response-activating signal transduction + 320
              immune response-inhibiting signal transduction + 5
              immune response-regulating cell surface receptor signaling pathway + 339
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.