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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of type 2 immune response
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Accession:GO:0002828 term browser browse the term
Definition:Any process that modulates the frequency, rate, or extent of a type 2 immune response.
Synonyms:narrow_synonym: regulation of T-helper 2 type immune response;   regulation of Th2 immune response


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regulation of type 2 immune response term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ecm1 extracellular matrix protein 1 ISO MGI:MGI:4940879 (MGI:MGI:4887510|PMID:21217760) RGD PMID:21217760 MGI:MGI:4887510 NCBI chr 2:197,855,468...197,860,973
Ensembl chr 2:197,855,460...197,860,699
JBrowse link
negative regulation of T-helper 2 cell cytokine production term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arg1 arginase 1 ISO (MGI:MGI:5908339|PMID:19360123) RGD PMID:19360123 MGI:MGI:5908339 NCBI chr 1:21,525,421...21,537,872
Ensembl chr 1:21,525,421...21,537,863
JBrowse link
G Ifnb1 interferon beta 1 ISO (PMID:20554961) RGD PMID:20554961 NCBI chr 5:106,865,192...106,865,746
Ensembl chr 5:106,865,192...106,865,746
JBrowse link
G Tbx21 T-box transcription factor 21 ISO (MGI:MGI:5543347|PMID:23616576) RGD PMID:23616576 MGI:MGI:5543347 NCBI chr10:85,032,799...85,049,331
Ensembl chr10:85,032,799...85,049,331
JBrowse link
negative regulation of T-helper 2 cell differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa1 annexin A1 ISO
IBA
ISS
(PMID:17008549)
PMID:21873635
GO_REF:0000024
RGD
UniProt
PMID:17008549, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 1:237,893,983...237,910,002
Ensembl chr 1:237,893,966...237,910,012
JBrowse link
G Bcl6 BCL6, transcription repressor ISO MGI:MGI:96559 (MGI:MGI:2450484|PMID:12594267) RGD PMID:12594267 MGI:MGI:2450484 NCBI chr11:80,255,790...80,279,075
Ensembl chr11:80,255,790...80,279,075
JBrowse link
G Hlx H2.0-like homeobox ISO MGI:MGI:105367|MGI:MGI:2182089 (MGI:MGI:3761239|PMID:16424184) RGD PMID:16424184 MGI:MGI:3761239 NCBI chr13:102,637,967...102,643,376
Ensembl chr13:102,637,769...102,643,223
JBrowse link
G Socs5 suppressor of cytokine signaling 5 ISO (MGI:MGI:3687909|PMID:12242343) RGD PMID:12242343 MGI:MGI:3687909 NCBI chr 6:10,671,311...10,705,610
Ensembl chr 6:10,674,371...10,704,977
JBrowse link
G Zfp35 zinc finger protein 35 ISO MGI:MGI:4398896 (MGI:MGI:4366385|PMID:19783676) RGD PMID:19783676 MGI:MGI:4366385 NCBI chr18:15,883,182...15,898,803
Ensembl chr18:15,883,182...15,898,821
JBrowse link
negative regulation of type 2 immune response term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arg2 arginase 2 IEA
ISO
GO_REF:0000107
(MGI:MGI:5810834|PMID:27214549)
Ensembl
RGD
PMID:27214549 GO_REF:0000107, MGI:MGI:5810834 NCBI chr 6:102,311,097...102,338,406
Ensembl chr 6:102,311,116...102,338,520
JBrowse link
G Bcl6 BCL6, transcription repressor ISO MGI:MGI:103034 (MGI:MGI:1342381|PMID:10438949) RGD PMID:10438949 MGI:MGI:1342381 NCBI chr11:80,255,790...80,279,075
Ensembl chr11:80,255,790...80,279,075
JBrowse link
G Ccr2 C-C motif chemokine receptor 2 ISO
ISS
(MGI:MGI:3699670|PMID:14662900)
GO_REF:0000024
RGD
BHF-UCL
PMID:14662900 GO_REF:0000024, MGI:MGI:3699670
G Ifnl1 interferon, lambda 1 ISO (PMID:19346497) RGD PMID:19346497 NCBI chr 1:85,252,103...85,253,635
Ensembl chr 1:85,252,103...85,253,635
JBrowse link
G Il27ra interleukin 27 receptor subunit alpha ISO MGI:MGI:3525439 (MGI:MGI:1926579|PMID:11057672) RGD PMID:11057672 MGI:MGI:1926579 NCBI chr19:25,151,835...25,163,995
Ensembl chr19:25,149,897...25,164,086
JBrowse link
G Ndfip1 Nedd4 family interacting protein 1 ISO MGI:MGI:3695433 (MGI:MGI:3694584|PMID:17137798) RGD PMID:17137798 MGI:MGI:3694584 NCBI chr18:31,574,759...31,625,286
Ensembl chr18:31,574,821...31,625,274
JBrowse link
G Stat6 signal transducer and activator of transcription 6 ISO MGI:MGI:107187 (MGI:MGI:1342381|PMID:10438949) RGD PMID:10438949 MGI:MGI:1342381 NCBI chr 7:70,946,228...70,963,542
Ensembl chr 7:70,946,228...70,964,484
JBrowse link
G Zfp35 zinc finger protein 35 ISO MGI:MGI:4398896 (MGI:MGI:4366385|PMID:19783676) RGD PMID:19783676 MGI:MGI:4366385 NCBI chr18:15,883,182...15,898,803
Ensembl chr18:15,883,182...15,898,821
JBrowse link
positive regulation of T-helper 2 cell cytokine production term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd81 Cd81 molecule ISS
ISO
IEA
GO_REF:0000024
(MGI:MGI:1926561|PMID:11046035)
(PMID:8766544)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:8766544, PMID:11046035 GO_REF:0000024, GO_REF:0000107, MGI:MGI:1926561 NCBI chr 1:216,237,663...216,253,460
Ensembl chr 1:216,237,697...216,253,311
JBrowse link
G Gata3 GATA binding protein 3 ISO (MGI:MGI:3046385|PMID:15087456) RGD PMID:15087456 MGI:MGI:3046385 NCBI chr17:72,419,752...72,452,043
Ensembl chr17:72,429,618...72,450,681
JBrowse link
G Il6 interleukin 6 ISO (MGI:MGI:5795829|PMID:11159963) RGD PMID:11159963 MGI:MGI:5795829 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 ISO (MGI:MGI:5689221|PMID:26098997) RGD PMID:26098997 MGI:MGI:5689221 NCBI chr10:45,884,324...45,918,290
Ensembl chr10:45,893,018...45,918,254
JBrowse link
G Prkcz protein kinase C, zeta ISO
ISS
(MGI:MGI:3584076|PMID:15987782)
GO_REF:0000024
RGD
UniProt
PMID:15987782 GO_REF:0000024, MGI:MGI:3584076 NCBI chr 5:172,658,071...172,769,492
Ensembl chr 5:172,658,748...172,769,421
JBrowse link
G Rsad2 radical S-adenosyl methionine domain containing 2 IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(MGI:MGI:3844206|PMID:19047684)
Ensembl
UniProt
RGD
PMID:19047684 GO_REF:0000024, GO_REF:0000107, MGI:MGI:3844206 NCBI chr 6:45,655,947...45,669,083
Ensembl chr 6:45,655,954...45,669,148
JBrowse link
G Xcl1 X-C motif chemokine ligand 1 ISO
IEA
(MGI:MGI:5009207|PMID:9973465)
GO_REF:0000107
RGD
Ensembl
PMID:9973465 GO_REF:0000107, MGI:MGI:5009207 NCBI chr13:83,199,402...83,202,845
Ensembl chr13:83,199,264...83,202,864
JBrowse link
positive regulation of T-helper 2 cell differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il18 interleukin 18 ISO
IEA
(MGI:MGI:3608083|PMID:12829194)
GO_REF:0000107
RGD
Ensembl
PMID:12829194 GO_REF:0000107, MGI:MGI:3608083 NCBI chr 8:55,009,666...55,016,286
Ensembl chr 8:54,993,859...55,016,299
JBrowse link
G Il4r interleukin 4 receptor ISO MGI:MGI:96109 (MGI:MGI:3761239|PMID:16424184) RGD PMID:16424184 MGI:MGI:3761239 NCBI chr 1:196,942,343...196,967,221
Ensembl chr 1:196,942,364...196,967,220
JBrowse link
G Il6 interleukin 6 ISO (MGI:MGI:2450484|PMID:12594267) RGD PMID:12594267 MGI:MGI:2450484 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 ISO (MGI:MGI:5689221|PMID:26098997) RGD PMID:26098997 MGI:MGI:5689221 NCBI chr10:45,884,324...45,918,290
Ensembl chr10:45,893,018...45,918,254
JBrowse link
G Prkcz protein kinase C, zeta ISO
ISS
(MGI:MGI:3584076|PMID:15987782)
GO_REF:0000024
RGD
UniProt
PMID:15987782 GO_REF:0000024, MGI:MGI:3584076 NCBI chr 5:172,658,071...172,769,492
Ensembl chr 5:172,658,748...172,769,421
JBrowse link
G Rara retinoic acid receptor, alpha ISO (PMID:18416830) RGD PMID:18416830 NCBI chr10:86,838,819...86,884,224
Ensembl chr10:86,860,685...86,884,210
JBrowse link
G Tnfsf4 TNF superfamily member 4 ISO (MGI:MGI:4943387|PMID:18354165) RGD PMID:18354165 MGI:MGI:4943387 NCBI chr13:79,269,973...79,293,775
Ensembl chr13:79,269,973...79,293,778
JBrowse link
positive regulation of type 2 immune response term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd74 CD74 molecule ISO
IBA
(MGI:MGI:2158514|PMID:11823488)
PMID:21873635
RGD PMID:11823488, PMID:21873635 MGI:MGI:2158514, RGD:13792537 NCBI chr18:56,071,420...56,080,851
Ensembl chr18:56,071,478...56,080,849
JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 ISO
IEA
MGI:MGI:3505776 (MGI:MGI:3789443|PMID:18436652)
GO_REF:0000107
RGD
Ensembl
PMID:18436652 GO_REF:0000107, MGI:MGI:3789443 NCBI chr16:72,216,326...72,228,098
Ensembl chr16:72,216,326...72,228,098
JBrowse link
G Il33 interleukin 33 ISO
IEA
UniProtKB:P08226 (MGI:MGI:3775141|PMID:18268038), (MGI:MGI:5543337|PMID:23630360)
GO_REF:0000107
RGD
Ensembl
PMID:18268038, PMID:23630360 GO_REF:0000107, MGI:MGI:3775141, MGI:MGI:5543337 NCBI chr 1:248,112,611...248,147,030
Ensembl chr 1:248,132,090...248,147,029
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 ISO (MGI:MGI:5689221|PMID:26098997) RGD PMID:26098997 MGI:MGI:5689221 NCBI chr10:45,884,324...45,918,290
Ensembl chr10:45,893,018...45,918,254
JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 ISO (PMID:21172192) RGD PMID:21172192 NCBI chr19:19,342,061...19,389,366
Ensembl chr19:19,332,594...19,377,492
JBrowse link
G Tnfsf4 TNF superfamily member 4 ISO (MGI:MGI:3763508|PMID:12496423), (MGI:MGI:4355816|PMID:17785785), (MGI:MGI:4943387|PMID:18354165) RGD PMID:12496423, PMID:17785785, PMID:18354165 MGI:MGI:3763508, MGI:MGI:4355816, MGI:MGI:4943387 NCBI chr13:79,269,973...79,293,775
Ensembl chr13:79,269,973...79,293,778
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20028
    immune system process 2843
      immune response 1746
        type 2 immune response 35
          regulation of type 2 immune response 30
            negative regulation of type 2 immune response + 14
            positive regulation of type 2 immune response + 15
            regulation of T-helper 2 cell cytokine production + 10
            regulation of T-helper 2 cell differentiation + 12
Path 2
Term Annotations click to browse term
  biological_process 20028
    biological regulation 13773
      regulation of biological process 13075
        regulation of immune system process 1482
          regulation of immune response 839
            regulation of type 2 immune response 30
              negative regulation of type 2 immune response + 14
              positive regulation of type 2 immune response + 15
              regulation of T-helper 2 cell cytokine production + 10
              regulation of T-helper 2 cell differentiation + 12
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.