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ONTOLOGY REPORT - ANNOTATIONS


Term:T cell anergy
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Accession:GO:0002870 term browser browse the term
Definition:Any process contributing to anergy in T cells, a state of functional inactivation which is part of T cell tolerance induction.
Synonyms:exact_synonym: T lymphocyte anergy


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negative regulation of T cell anergy term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD86 CD86 molecule ISO RGD PMID:18424705 RGD:4892228 NCBI chr 3:119,151,884...119,217,641
Ensembl chr 3:126,059,008...126,124,339
JBrowse link
positive regulation of T cell anergy term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CBLB Cbl proto-oncogene B ISO (MGI:3038342|PMID:14973438) MGI PMID:14973438 MGI:3038342 NCBI chr 3:102,752,406...102,966,414
Ensembl chr 3:109,690,120...109,905,191
JBrowse link
G CD3E CD3e molecule ISO (MGI:3038342|PMID:14973438) MGI PMID:14973438 MGI:3038342 NCBI chr11:113,142,200...113,153,928
Ensembl chr11:117,074,041...117,085,625
JBrowse link
G FOXP3 forkhead box P3 ISO (MGI:3692513|PMID:16945588) MGI PMID:16945588 MGI:3692513 NCBI chr  X:41,550,462...41,567,492
Ensembl chr  X:49,402,652...49,417,029
JBrowse link
G ITCH itchy E3 ubiquitin protein ligase ISO (MGI:3038342|PMID:14973438) MGI PMID:14973438 MGI:3038342 NCBI chr20:30,690,172...30,840,504
Ensembl chr20:31,852,203...31,971,945
JBrowse link
G LILRB4 leukocyte immunoglobulin like receptor B4 ISO (PMID:16493035) ARUK-UCL PMID:16493035 NCBI chr19:51,606,681...51,612,751 JBrowse link
regulation of T cell anergy term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FOXP3 forkhead box P3 ISO (MGI:3710039|PMID:17377532) UniProt PMID:17377532 MGI:3710039 NCBI chr  X:41,550,462...41,567,492
Ensembl chr  X:49,402,652...49,417,029
JBrowse link
G LOC100982859 patr class I histocompatibility antigen, B-2 alpha chain ISO (PMID:20008523) BHF-UCL PMID:20008523 NCBI chr 6:31,106,562...31,109,933
Ensembl chr 6:31,997,381...32,000,067
JBrowse link
G PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 ISO (MGI:5013552|PMID:21498666) UniProt PMID:21498666 MGI:5013552 NCBI chr18:56,084,851...56,338,551 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12566
    immune system process 2073
      tolerance induction 29
        T cell tolerance induction 13
          T cell anergy 8
            negative regulation of T cell anergy 1
            positive regulation of T cell anergy 5
            regulation of T cell anergy + 8
Path 2
Term Annotations click to browse term
  biological_process 12566
    developmental process 5839
      anatomical structure development 5452
        multicellular organism development 4984
          system development 4688
            immune system development 968
              tolerance induction 29
                T cell tolerance induction 13
                  T cell anergy 8
                    negative regulation of T cell anergy 1
                    positive regulation of T cell anergy 5
                    regulation of T cell anergy + 8
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.