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ONTOLOGY REPORT - ANNOTATIONS


Term:T cell anergy
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Accession:GO:0002870 term browser browse the term
Definition:Any process contributing to anergy in T cells, a state of functional inactivation which is part of T cell tolerance induction.
Synonyms:exact_synonym: T lymphocyte anergy


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negative regulation of T cell anergy term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD86 CD86 molecule ISO RGD PMID:18424705 RGD:4892228 NCBI chr33:25,256,267...25,318,855
Ensembl chr33:25,256,267...25,318,087
JBrowse link
positive regulation of T cell anergy term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CBLB Cbl proto-oncogene B ISO (MGI:3038342|PMID:14973438) MGI PMID:14973438 MGI:3038342 NCBI chr33:11,255,453...11,665,755
Ensembl chr33:11,199,863...11,530,810
JBrowse link
G CD3E CD3e molecule IEA Ensembl GO_REF:0000107 NCBI chr 5:15,403,724...15,415,259
Ensembl chr 5:15,403,710...15,415,260
JBrowse link
G FOXP3 forkhead box P3 IEA Ensembl GO_REF:0000107 NCBI chr  X:42,331,229...42,362,841
Ensembl chr  X:42,344,108...42,350,758
JBrowse link
G ITCH itchy E3 ubiquitin protein ligase IEA Ensembl GO_REF:0000107 NCBI chr24:23,476,619...23,630,574
Ensembl chr24:23,476,736...23,627,469
JBrowse link
G LOC484306 leukocyte immunoglobulin-like receptor subfamily B member 3 ISO (PMID:16493035) ARUK-UCL PMID:16493035 NCBI chr 1:102,779,562...102,786,924 JBrowse link
regulation of T cell anergy term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DLA-64 MHC class I DLA-64 ISO (PMID:20008523) BHF-UCL PMID:20008523 NCBI chr12:983,573...986,969 JBrowse link
G FOXP3 forkhead box P3 ISO (MGI:3710039|PMID:17377532) UniProt PMID:17377532 MGI:3710039 NCBI chr  X:42,331,229...42,362,841
Ensembl chr  X:42,344,108...42,350,758
JBrowse link
G PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 IEA Ensembl GO_REF:0000107 NCBI chr 1:14,027,741...14,234,229
Ensembl chr 1:14,028,652...14,234,229
JBrowse link
G RUNX1 RUNX family transcription factor 1 ISO (MGI:3710039|PMID:17377532) UniProt PMID:17377532 MGI:3710039 NCBI chr31:30,170,859...30,420,344
Ensembl chr31:30,170,605...30,420,839
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16190
    immune system process 2290
      tolerance induction 32
        T cell tolerance induction 14
          T cell anergy 9
            negative regulation of T cell anergy 1
            positive regulation of T cell anergy 5
            regulation of T cell anergy + 9
Path 2
Term Annotations click to browse term
  biological_process 16190
    developmental process 6310
      anatomical structure development 5858
        multicellular organism development 5351
          system development 4984
            immune system development 1025
              tolerance induction 32
                T cell tolerance induction 14
                  T cell anergy 9
                    negative regulation of T cell anergy 1
                    positive regulation of T cell anergy 5
                    regulation of T cell anergy + 9
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.