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ONTOLOGY REPORT - ANNOTATIONS


Term:T cell anergy
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Accession:GO:0002870 term browser browse the term
Definition:Any process contributing to anergy in T cells, a state of functional inactivation which is part of T cell tolerance induction.
Synonyms:exact_synonym: T lymphocyte anergy


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negative regulation of T cell anergy term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD86 CD86 molecule ISO RGD PMID:18424705 RGD:4892228 NCBI chr 3:122,055,362...122,121,136
Ensembl chr 3:122,055,362...122,121,139
JBrowse link
positive regulation of T cell anergy term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CBLB Cbl proto-oncogene B ISO (MGI:3038342|PMID:14973438) MGI PMID:14973438 MGI:3038342 NCBI chr 3:105,655,461...105,869,552
Ensembl chr 3:105,655,461...105,869,552
JBrowse link
G CD3E CD3e molecule IEA Ensembl GO_REF:0000107 NCBI chr11:118,304,730...118,316,173
Ensembl chr11:118,304,730...118,316,175
Ensembl chr11:118,304,730...118,316,175
JBrowse link
G FOXP3 forkhead box P3 IEA Ensembl GO_REF:0000107 NCBI chr  X:49,250,436...49,264,932
Ensembl chr  X:49,250,438...49,270,477
Ensembl chr  X:49,250,438...49,270,477
JBrowse link
G ITCH itchy E3 ubiquitin protein ligase IEA Ensembl GO_REF:0000107 NCBI chr20:34,363,273...34,511,773
Ensembl chr20:34,363,241...34,540,748
JBrowse link
G LILRB4 leukocyte immunoglobulin like receptor B4 IMP (PMID:16493035) ARUK-UCL PMID:16493035 NCBI chr19:54,662,524...54,670,359
Ensembl chr19:54,643,889...54,670,359
JBrowse link
regulation of T cell anergy term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLC Charcot-Leyden crystal galectin IMP (PMID:17502455) UniProtKB PMID:17502455 NCBI chr19:39,731,255...39,738,029
Ensembl chr19:39,731,255...39,738,029
JBrowse link
G FOXP3 forkhead box P3 ISS UniProtKB GO_REF:0000024 NCBI chr  X:49,250,436...49,264,932
Ensembl chr  X:49,250,438...49,270,477
Ensembl chr  X:49,250,438...49,270,477
JBrowse link
G HLA-B major histocompatibility complex, class I, B IMP (PMID:20008523) BHF-UCL PMID:20008523 NCBI chr 6:31,353,875...31,357,179
Ensembl chr 6:31,269,491...31,357,188
JBrowse link
G PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 IEA Ensembl GO_REF:0000107 NCBI chr18:62,715,445...62,980,433
Ensembl chr18:62,715,541...62,980,433
JBrowse link
G RUNX1 RUNX family transcription factor 1 ISO (MGI:3710039|PMID:17377532) UniProt PMID:17377532 MGI:3710039 NCBI chr21:34,787,801...35,049,334
Ensembl chr21:34,787,801...36,004,667
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18672
    immune system process 3582
      tolerance induction 35
        T cell tolerance induction 17
          T cell anergy 10
            negative regulation of T cell anergy 1
            positive regulation of T cell anergy 5
            regulation of T cell anergy + 10
Path 2
Term Annotations click to browse term
  biological_process 18672
    developmental process 7466
      anatomical structure development 6873
        multicellular organism development 6346
          system development 5749
            immune system development 1221
              tolerance induction 35
                T cell tolerance induction 17
                  T cell anergy 10
                    negative regulation of T cell anergy 1
                    positive regulation of T cell anergy 5
                    regulation of T cell anergy + 10
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.