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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of heart rate by chemical signal
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Accession:GO:0003062 term browser browse the term
Definition:The regulation of the rate of heart contraction mediated by chemical signaling, hormonal, autocrine or paracrine.
Synonyms:exact_synonym: chemical cardiac chronotropy;   chemical signal regulation of heart rate
 related_synonym: chemical signal regulation of heart contraction rate


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regulation of heart rate by chemical signal term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ffar3 free fatty acid receptor 3 ISO MGI:MGI:5013799 (MGI:MGI:5009064|PMID:21518883) RGD PMID:21518883 MGI:MGI:5009064 NCBI chr 1:89,302,035...89,304,064
Ensembl chr 1:89,302,039...89,303,968
JBrowse link
G Nos1ap nitric oxide synthase 1 adaptor protein ISO (PMID:19247217) RGD PMID:19247217 NCBI chr13:88,653,123...88,943,976 JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 ISO MGI:MGI:2177773 (MGI:MGI:3772404|PMID:18060044) RGD PMID:18060044 MGI:MGI:3772404 NCBI chr10:46,570,996...46,593,021
Ensembl chr10:46,570,996...46,593,009
JBrowse link
adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pde4d phosphodiesterase 4D IC PMID:19801680 BHF-UCL PMID:19801680 RGD:7327160 NCBI chr 2:40,219,999...41,468,551
Ensembl chr 2:40,554,146...41,464,264
JBrowse link
negative regulation of heart rate by acetylcholine term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrm3 cholinergic receptor, muscarinic 3 IMP RGD PMID:9316844 RGD:2303391 NCBI chr17:63,990,599...64,463,222
Ensembl chr17:63,990,599...63,994,169
JBrowse link
positive regulation of heart rate by epinephrine term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tpm1 tropomyosin 1 ISO
IEA
(MGI:MGI:3802907|PMID:17556658)
GO_REF:0000107
RGD
Ensembl
PMID:17556658 GO_REF:0000107, MGI:MGI:3802907 NCBI chr 8:72,814,737...72,841,496
Ensembl chr 8:72,814,740...72,842,228
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20017
    biological regulation 13767
      regulation of biological quality 4283
        regulation of heart rate 109
          regulation of heart rate by chemical signal 6
            adenylate cyclase-activating adrenergic receptor signaling pathway involved in regulation of heart rate + 1
            negative regulation of heart rate by acetylcholine + 1
            positive regulation of heart rate by epinephrine + 1
            positive regulation of heart rate by norepinephrine + 0
            regulation of heart rate by hormone 0
Path 2
Term Annotations click to browse term
  biological_process 20017
    multicellular organismal process 9055
      system process 3445
        circulatory system process 578
          blood circulation 550
            heart contraction 246
              regulation of heart contraction 200
                regulation of heart rate 109
                  regulation of heart rate by chemical signal 6
                    adenylate cyclase-activating adrenergic receptor signaling pathway involved in regulation of heart rate + 1
                    negative regulation of heart rate by acetylcholine + 1
                    positive regulation of heart rate by epinephrine + 1
                    positive regulation of heart rate by norepinephrine + 0
                    regulation of heart rate by hormone 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.