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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of systemic arterial blood pressure
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Accession:GO:0003085 term browser browse the term
Definition:The process that reduces the force with which blood travels through the systemic arterial circulatory system.


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negative regulation of systemic arterial blood pressure term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora1 adenosine A1 receptor IDA RGD PMID:9597368 RGD:1625365 NCBI chr13:51,042,111...51,076,913
Ensembl chr13:51,042,248...51,076,852
JBrowse link
G Ahr aryl hydrocarbon receptor ISO (MGI:MGI:3760685|PMID:14644620) RGD PMID:14644620 MGI:MGI:3760685 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Arhgap42 Rho GTPase activating protein 42 ISO MGI:MGI:1096342 (MGI:MGI:5638847|PMID:24335996) RGD PMID:24335996 MGI:MGI:5638847 NCBI chr 8:7,210,999...7,446,215
Ensembl chr 8:7,213,822...7,426,611
JBrowse link
G Bbs4 Bardet-Biedl syndrome 4 ISO MGI:MGI:3045473 (MGI:MGI:3794515|PMID:18317593) RGD PMID:18317593 MGI:MGI:3794515 NCBI chr 8:64,115,005...64,154,432
Ensembl chr 8:64,121,392...64,154,396
JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 ISO (PMID:18364108) RGD PMID:18364108 NCBI chr 9:66,568,074...66,683,019
Ensembl chr 9:66,568,074...66,676,494
JBrowse link
G Cd36 CD36 molecule IMP RGD PMID:22128087 RGD:6893560 NCBI chr 4:14,150,309...14,191,498
Ensembl chr 4:14,001,761...14,249,749
JBrowse link
G Crh corticotropin releasing hormone IDA RGD PMID:7477349 RGD:70047 NCBI chr 2:104,459,999...104,461,863
Ensembl chr 2:104,459,999...104,461,863
JBrowse link
G Gpr37l1 G protein-coupled receptor 37-like 1 ISS
ISO
IEA
GO_REF:0000024
(MGI:MGI:6150990|PMID:29625592)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:29625592 GO_REF:0000024, GO_REF:0000107, MGI:MGI:6150990 NCBI chr13:51,985,698...51,992,547
Ensembl chr13:51,985,684...51,992,693
JBrowse link
G Ier3 immediate early response 3 ISO MGI:MGI:3773690 (MGI:MGI:3772966|PMID:16166241) RGD PMID:16166241 MGI:MGI:3772966 NCBI chr20:3,438,798...3,440,002
Ensembl chr20:3,438,798...3,440,769
JBrowse link
G Kcnk6 potassium two pore domain channel subfamily K member 6 ISO MGI:MGI:2155245 (MGI:MGI:5499932|PMID:23637138) RGD PMID:23637138 MGI:MGI:5499932 NCBI chr 1:88,168,438...88,176,610
Ensembl chr 1:88,169,378...88,176,610
JBrowse link
G Kl Klotho IMP RGD PMID:20086041 RGD:10403068 NCBI chr12:942,974...987,206
Ensembl chr12:943,006...987,551
JBrowse link
G Nedd4l NEDD4 like E3 ubiquitin protein ligase ISO MGI:MGI:3846431 (MGI:MGI:3846015|PMID:18524855) RGD PMID:18524855 MGI:MGI:3846015 NCBI chr18:60,392,376...60,719,720
Ensembl chr18:60,392,376...60,719,720
JBrowse link
G Nppa natriuretic peptide A IDA
IBA
PMID:21873635 RGD
GO_Central
PMID:2136863, PMID:21873635 RGD:7247720, RGD:13792537 NCBI chr 5:164,808,407...164,809,716
Ensembl chr 5:164,808,323...164,809,705
JBrowse link
G Nppb natriuretic peptide B IDA
IBA
PMID:21873635 RGD
GO_Central
PMID:8289999, PMID:21403100, PMID:21873635 RGD:7247315, RGD:5685657, RGD:13792537 NCBI chr 5:164,796,176...164,797,538
Ensembl chr 5:164,796,185...164,797,531
JBrowse link
G Ntsr1 neurotensin receptor 1 IMP RGD PMID:22211865 RGD:9727449 NCBI chr 3:175,982,313...176,046,345
Ensembl chr 3:175,885,894...176,046,345
JBrowse link
G Prcp prolylcarboxypeptidase ISO
IBA
MGI:MGI:4123993 (MGI:MGI:5009114|PMID:21297000)
PMID:21873635
RGD PMID:21297000, PMID:21873635 MGI:MGI:5009114, RGD:13792537 NCBI chr 1:157,701,089...157,750,177
Ensembl chr 1:157,701,089...157,750,169
JBrowse link
G Smtn smoothelin ISO MGI:MGI:3613293 (MGI:MGI:4437553|PMID:18678771) RGD PMID:18678771 MGI:MGI:4437553 NCBI chr14:83,755,141...83,776,871
Ensembl chr14:83,755,142...83,776,863
JBrowse link
G Tac1 tachykinin, precursor 1 ISO (PMID:12716968) RGD PMID:12716968 NCBI chr 4:33,638,853...33,646,819
Ensembl chr 4:33,638,709...33,646,819
JBrowse link
G Tac4 tachykinin precursor 4 ISO (PMID:12716968) RGD PMID:12716968 NCBI chr10:83,081,168...83,089,487
Ensembl chr10:83,081,168...83,089,481
JBrowse link
G Tnf tumor necrosis factor IMP RGD PMID:7875478 RGD:14975128 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 IMP RGD PMID:27335281 RGD:13792700 NCBI chr10:59,799,123...59,824,208
Ensembl chr10:59,799,123...59,824,679
JBrowse link
acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sod2 superoxide dismutase 2 ISO MGI:MGI:1857129|MGI:MGI:1857480 (MGI:MGI:3765405|PMID:16873728) RGD PMID:16873728 MGI:MGI:3765405 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
angiotensin-mediated vasodilation involved in regulation of systemic arterial blood pressure term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agtr2 angiotensin II receptor, type 2 ISO MGI:MGI:1857123 (MGI:MGI:1342129|PMID:10425188) RGD PMID:10425188 MGI:MGI:1342129 NCBI chr  X:119,389,480...119,393,845
Ensembl chr  X:119,390,013...119,393,842
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase ISO MGI:MGI:2182739 (MGI:MGI:3694178|PMID:15998684) RGD PMID:15998684 MGI:MGI:3694178 NCBI chr  X:156,274,800...156,293,935
Ensembl chr  X:156,274,800...156,293,926
JBrowse link
artery vasodilation involved in baroreceptor response to increased systemic arterial blood pressure term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Calca calcitonin-related polypeptide alpha ISO MGI:MGI:2445489 (MGI:MGI:2445452|PMID:11717154) RGD PMID:11717154 MGI:MGI:2445452 NCBI chr 1:184,184,018...184,188,922
Ensembl chr 1:184,184,020...184,188,911
JBrowse link
negative regulation of heart rate involved in baroreceptor response to increased systemic arterial blood pressure term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adra1a adrenoceptor alpha 1A ISO MGI:MGI:2387663 (MGI:MGI:2182494|PMID:12093905) RGD PMID:12093905 MGI:MGI:2182494 NCBI chr15:43,296,997...43,398,314
Ensembl chr15:43,298,794...43,392,451
JBrowse link
negative regulation of the force of heart contraction involved in baroreceptor response to increased systemic arterial blood pressure term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adra1d adrenoceptor alpha 1D ISO (MGI:MGI:2656483|PMID:12595294) RGD PMID:12595294 MGI:MGI:2656483 NCBI chr 3:124,129,558...124,145,566
Ensembl chr 3:124,129,558...124,145,566
JBrowse link
norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrb1 adrenoceptor beta 1 IEA
IBA
ISO
GO_REF:0000107
PMID:21873635
MGI:MGI:1857120|MGI:MGI:87938 (MGI:MGI:1338641|PMID:10358009), (MGI:MGI:3608195|PMID:11641423)
Ensembl
RGD
PMID:10358009, PMID:11641423, PMID:21873635 GO_REF:0000107, MGI:MGI:1338641, MGI:MGI:3608195, RGD:13792537 NCBI chr 1:277,537,585...277,538,985
Ensembl chr 1:277,537,585...277,538,985
JBrowse link
G Adrb2 adrenoceptor beta 2 IEA
IBA
ISO
GO_REF:0000107
PMID:21873635
MGI:MGI:1859675|MGI:MGI:87937 (MGI:MGI:1338641|PMID:10358009), (MGI:MGI:3608195|PMID:11641423)
Ensembl
RGD
PMID:10358009, PMID:11641423, PMID:21873635 GO_REF:0000107, MGI:MGI:1338641, MGI:MGI:3608195, RGD:13792537 NCBI chr18:57,513,792...57,515,834
Ensembl chr18:57,513,793...57,515,834
JBrowse link
G Adrb3 adrenoceptor beta 3 ISO
IBA
(MGI:MGI:1338641|PMID:10358009)
PMID:21873635
RGD PMID:10358009, PMID:21873635 MGI:MGI:1338641, RGD:13792537 NCBI chr16:69,003,541...69,006,632
Ensembl chr16:69,003,868...69,006,632
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20014
    biological regulation 13759
      regulation of biological quality 4284
        regulation of blood pressure 219
          regulation of systemic arterial blood pressure 124
            negative regulation of systemic arterial blood pressure 30
              acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure 1
              angiotensin-mediated vasodilation involved in regulation of systemic arterial blood pressure 2
              baroreceptor response to increased systemic arterial blood pressure + 3
              norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure 3
              regulation of systemic arterial blood pressure by stress relaxation 0
Path 2
Term Annotations click to browse term
  biological_process 20014
    multicellular organismal process 9055
      system process 3445
        circulatory system process 578
          blood circulation 550
            regulation of blood pressure 219
              negative regulation of blood pressure 66
                negative regulation of systemic arterial blood pressure 30
                  acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure 1
                  angiotensin-mediated vasodilation involved in regulation of systemic arterial blood pressure 2
                  baroreceptor response to increased systemic arterial blood pressure + 3
                  norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure 3
                  regulation of systemic arterial blood pressure by stress relaxation 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.