Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:heart induction
go back to main search page
Accession:GO:0003129 term browser browse the term
Definition:The close range interaction between mesoderm and endoderm or ectoderm that causes cells to change their fates and specify the development of the heart.


show annotations for term's descendants           Sort by:
 
BMP signaling pathway involved in heart induction term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp2 bone morphogenetic protein 2 ISO
ISS
(PMID:19736317)
GO_REF:0000024
RGD
UniProt
PMID:19736317 GO_REF:0000024 NCBI chr 3:126,335,963...126,346,771
Ensembl chr 3:126,335,863...126,346,318
JBrowse link
G Bmp4 bone morphogenetic protein 4 ISO
ISS
IEA
(PMID:20702560)
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:20702560 GO_REF:0000024, GO_REF:0000107 NCBI chr15:20,776,060...20,791,013
Ensembl chr15:20,776,054...20,822,740
JBrowse link
G Pou5f1 POU class 5 homeobox 1 ISO (PMID:19736317) RGD PMID:19736317 NCBI chr20:3,747,231...3,751,994
Ensembl chr20:3,747,221...3,751,994
JBrowse link
negative regulation of heart induction by canonical Wnt signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wnt3a Wnt family member 3A ISO (PMID:19736317) RGD PMID:19736317 NCBI chr10:45,598,898...45,643,151
Ensembl chr10:45,598,912...45,638,035
JBrowse link
positive regulation of heart induction by negative regulation of canonical Wnt signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 ISO (MGI:3835736|PMID:18297060) RGD PMID:18297060 MGI:3835736 NCBI chr 1:248,952,896...248,956,579
Ensembl chr 1:248,895,738...248,898,607
JBrowse link
G Mesp1 mesoderm posterior bHLH transcription factor 1 ISO (MGI:3835736|PMID:18297060) RGD PMID:18297060 MGI:3835736 NCBI chr 1:141,532,390...141,533,908
Ensembl chr 1:141,532,390...141,533,908
JBrowse link
G Wnt11 Wnt family member 11 ISO UniProtKB:P22725 (MGI:5424267|PMID:22569553) RGD PMID:22569553 MGI:5424267 NCBI chr 1:163,794,136...163,813,756
Ensembl chr 1:163,797,660...163,813,756
JBrowse link
G Wnt5a Wnt family member 5A IEA
ISO
GO_REF:0000107
UniProtKB:P48615 (MGI:5424267|PMID:22569553)
Ensembl
RGD
PMID:22569553 GO_REF:0000107, MGI:5424267 NCBI chr16:4,469,451...4,490,271
Ensembl chr16:4,469,468...4,489,860
JBrowse link
positive regulation of Notch signaling pathway involved in heart induction term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gata5 GATA binding protein 5 ISO (MGI:5286818|PMID:21633169) RGD PMID:21633169 MGI:5286818 NCBI chr 3:175,701,278...175,709,465
Ensembl chr 3:175,701,280...175,709,465
JBrowse link
G Mesp1 mesoderm posterior bHLH transcription factor 1 ISO (MGI:4441249|PMID:18593560) RGD PMID:18593560 MGI:4441249 NCBI chr 1:141,532,390...141,533,908
Ensembl chr 1:141,532,390...141,533,908
JBrowse link
G Robo1 roundabout guidance receptor 1 ISO (MGI:5913048|PMID:25691540) RGD PMID:25691540 MGI:5913048 NCBI chr11:9,079,291...10,146,302
Ensembl chr11:9,642,365...10,143,317
JBrowse link
G Robo2 roundabout guidance receptor 2 ISO (MGI:5913048|PMID:25691540) RGD PMID:25691540 MGI:5913048 NCBI chr11:11,062,866...12,618,793
Ensembl chr11:11,062,790...11,585,765
JBrowse link
regulation of heart induction by regulation of canonical Wnt signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pou5f1 POU class 5 homeobox 1 ISO (PMID:19736317) RGD PMID:19736317 NCBI chr20:3,747,231...3,751,994
Ensembl chr20:3,747,221...3,751,994
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20020
    developmental process 6826
      developmental induction 44
        organ induction 29
          heart induction 11
            Notch signaling pathway involved in heart induction + 4
            endodermal-mesodermal cell signaling involved in heart induction + 3
            fibroblast growth factor receptor signaling pathway involved in heart induction 0
            mesodermal-endodermal cell signaling involved in heart induction 0
            negative regulation of heart induction + 1
            positive regulation of heart induction + 4
            regulation of heart induction + 6
Path 2
Term Annotations click to browse term
  biological_process 20020
    developmental process 6826
      anatomical structure development 6268
        multicellular organism development 5743
          system development 5279
            animal organ development 4033
              animal organ morphogenesis 1151
                animal organ formation 76
                  regulation of animal organ formation 34
                    organ induction 29
                      heart induction 11
                        Notch signaling pathway involved in heart induction + 4
                        endodermal-mesodermal cell signaling involved in heart induction + 3
                        fibroblast growth factor receptor signaling pathway involved in heart induction 0
                        mesodermal-endodermal cell signaling involved in heart induction 0
                        negative regulation of heart induction + 1
                        positive regulation of heart induction + 4
                        regulation of heart induction + 6
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.