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ONTOLOGY REPORT - ANNOTATIONS


Term:heart induction
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Accession:GO:0003129 term browser browse the term
Definition:The close range interaction between mesoderm and endoderm or ectoderm that causes cells to change their fates and specify the development of the heart.


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BMP signaling pathway involved in heart induction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp2 bone morphogenetic protein 2 JBrowse link 3 126,335,963 126,346,771 RGD:1624291
RGD:1600115
G Bmp4 bone morphogenetic protein 4 JBrowse link 15 20,776,060 20,791,013 RGD:1624291
RGD:1600115
G Pou5f1 POU class 5 homeobox 1 JBrowse link 20 3,747,231 3,751,994 RGD:1624291
negative regulation of heart induction by canonical Wnt signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Wnt3a Wnt family member 3A JBrowse link 10 45,598,898 45,643,151 RGD:1624291
RGD:1600115
positive regulation of heart induction by negative regulation of canonical Wnt signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 JBrowse link 1 248,952,896 248,956,579 RGD:1624291
G Mesp1 mesoderm posterior bHLH transcription factor 1 JBrowse link 1 141,532,390 141,533,908 RGD:1624291
RGD:1600115
positive regulation of Notch signaling pathway involved in heart induction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gata5 GATA binding protein 5 JBrowse link 3 175,701,278 175,709,465 RGD:1600115
RGD:1624291
G Mesp1 mesoderm posterior bHLH transcription factor 1 JBrowse link 1 141,532,390 141,533,908 RGD:1624291
RGD:1600115
G Robo1 roundabout guidance receptor 1 JBrowse link 11 9,079,291 10,146,302 RGD:1624291
G Robo2 roundabout guidance receptor 2 JBrowse link 11 11,062,866 12,618,793 RGD:1624291
regulation of heart induction by regulation of canonical Wnt signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pou5f1 POU class 5 homeobox 1 JBrowse link 20 3,747,231 3,751,994 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19245
    developmental process 6597
      developmental induction 42
        organ induction 27
          heart induction 9
            Notch signaling pathway involved in heart induction + 4
            endodermal-mesodermal cell signaling involved in heart induction + 3
            fibroblast growth factor receptor signaling pathway involved in heart induction 0
            mesodermal-endodermal cell signaling involved in heart induction 0
            negative regulation of heart induction + 1
            positive regulation of heart induction + 5
            regulation of heart induction + 7
Path 2
Term Annotations click to browse term
  biological_process 19245
    developmental process 6597
      anatomical structure development 6063
        multicellular organism development 5534
          system development 5081
            animal organ development 3881
              animal organ morphogenesis 1123
                animal organ formation 74
                  regulation of animal organ formation 43
                    organ induction 27
                      heart induction 9
                        Notch signaling pathway involved in heart induction + 4
                        endodermal-mesodermal cell signaling involved in heart induction + 3
                        fibroblast growth factor receptor signaling pathway involved in heart induction 0
                        mesodermal-endodermal cell signaling involved in heart induction 0
                        negative regulation of heart induction + 1
                        positive regulation of heart induction + 5
                        regulation of heart induction + 7
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.