Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:outflow tract morphogenesis
go back to main search page
Accession:GO:0003151 term browser browse the term
Definition:The process in which the anatomical structures of the outflow tract are generated and organized. The outflow tract is the portion of the heart through which blood flows into the arteries.


show annotations for term's descendants           Sort by:
 
outflow tract morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf2 activating transcription factor 2 ISO MGI:MGI:1857283 (MGI:MGI:3759355|PMID:17767158) RGD PMID:17767158 MGI:MGI:3759355 NCBI chr 3:60,721,137...60,795,951
Ensembl chr 3:60,721,135...60,795,951
JBrowse link
G Bmp4 bone morphogenetic protein 4 ISO RNAcentral:URS00002075FA_10090|RNAcentral:URS0000574A2C_10090|RNAcentral:URS000075EEC2_10090 (MGI:MGI:4939577|PMID:21145505) RGD PMID:21145505 MGI:MGI:4939577 NCBI chr15:20,776,060...20,791,013
Ensembl chr15:20,776,054...20,822,740
JBrowse link
G Bmpr1a bone morphogenetic protein receptor type 1A ISO (MGI:MGI:3040576|PMID:15073157) RGD PMID:15073157 MGI:MGI:3040576 NCBI chr16:10,758,278...10,852,170
Ensembl chr16:10,758,527...10,802,512
JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 ISO (MGI:MGI:3851675|PMID:19409885) RGD PMID:19409885 MGI:MGI:3851675 NCBI chr 9:66,568,074...66,683,019
Ensembl chr 9:66,568,074...66,676,494
JBrowse link
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 ISO MGI:MGI:2179740 (MGI:MGI:2179743|PMID:11694877), (MGI:MGI:3054669|PMID:15475956) RGD PMID:11694877, PMID:15475956 MGI:MGI:2179743, MGI:MGI:3054669 NCBI chr 1:12,823,363...12,825,806
Ensembl chr 1:12,823,363...12,825,786
JBrowse link
G Crkl CRK like proto-oncogene, adaptor protein ISO MGI:MGI:5763397|MGI:MGI:5763398 (MGI:MGI:5755897|PMID:25658046) RGD PMID:25658046 MGI:MGI:5755897 NCBI chr11:87,338,606...87,356,644
Ensembl chr11:87,778,312...87,815,043
JBrowse link
G Dhrs3 dehydrogenase/reductase 3 ISO MGI:MGI:5007106 (MGI:MGI:5528782|PMID:24005908) RGD PMID:24005908 MGI:MGI:5528782 NCBI chr 5:162,809,090...162,843,385
Ensembl chr 5:162,808,646...162,843,383
JBrowse link
G Dvl2 dishevelled segment polarity protein 2 ISO (MGI:MGI:2446944|PMID:12464179) RGD PMID:12464179 MGI:MGI:2446944 NCBI chr10:56,609,810...56,619,269
Ensembl chr10:56,610,051...56,619,269
JBrowse link
G Eln elastin ISO
IEA
(PMID:8132745)
GO_REF:0000107
RGD
Ensembl
PMID:8132745 GO_REF:0000107 NCBI chr12:24,978,478...25,021,864
Ensembl chr12:24,978,483...25,021,863
JBrowse link
G Eya1 EYA transcriptional coactivator and phosphatase 1 ISO MGI:MGI:102780|MGI:MGI:98493|MGI:MGI:99604 (MGI:MGI:5002778|PMID:21364285) RGD PMID:21364285 MGI:MGI:5002778 NCBI chr 5:4,275,728...4,495,525
Ensembl chr 5:4,373,626...4,513,142
JBrowse link
G Fgf8 fibroblast growth factor 8 ISO MGI:MGI:102780|MGI:MGI:109344|MGI:MGI:98493 (MGI:MGI:5002778|PMID:21364285) RGD PMID:21364285 MGI:MGI:5002778 NCBI chr 1:265,492,949...265,498,965
Ensembl chr 1:265,493,124...265,498,831
JBrowse link
G Foxh1 forkhead box H1 ISO (MGI:MGI:3055632|PMID:15363409) RGD PMID:15363409 MGI:MGI:3055632 NCBI chr 7:117,730,307...117,733,076
Ensembl chr 7:117,730,307...117,732,387
JBrowse link
G Fzd1 frizzled class receptor 1 ISO
IEA
MGI:MGI:1888513 (MGI:MGI:4837757|PMID:20940229)
GO_REF:0000107
RGD
Ensembl
PMID:20940229 GO_REF:0000107, MGI:MGI:4837757 NCBI chr 4:26,470,864...26,475,262
Ensembl chr 4:26,470,864...26,475,262
JBrowse link
G Fzd2 frizzled class receptor 2 ISO
IEA
MGI:MGI:1196625 (MGI:MGI:4837757|PMID:20940229)
GO_REF:0000107
RGD
Ensembl
PMID:20940229 GO_REF:0000107, MGI:MGI:4837757 NCBI chr10:90,550,147...90,552,057
Ensembl chr10:90,550,147...90,552,057
JBrowse link
G Gja5 gap junction protein, alpha 5 ISO (PMID:22199024) RGD PMID:22199024 NCBI chr 2:199,162,745...199,184,942
Ensembl chr 2:199,162,745...199,184,939
JBrowse link
G Hes1 hes family bHLH transcription factor 1 ISO (MGI:MGI:4354447|PMID:19609448), (MGI:MGI:4453944|PMID:20122914) RGD PMID:19609448, PMID:20122914 MGI:MGI:4354447, MGI:MGI:4453944 NCBI chr11:74,312,837...74,315,249
Ensembl chr11:74,312,806...74,315,248
JBrowse link
G Hey1 hes-related family bHLH transcription factor with YRPW motif 1 ISO UniProtKB:Q9DBX7 (MGI:MGI:3783952|PMID:17303760) RGD PMID:17303760 MGI:MGI:3783952 NCBI chr 2:95,320,147...95,322,701
Ensembl chr 2:95,320,283...95,322,696
JBrowse link
G Hey2 hes-related family bHLH transcription factor with YRPW motif 2 ISO (MGI:MGI:2386835|PMID:12372254) RGD PMID:12372254 MGI:MGI:2386835 NCBI chr 1:29,191,170...29,201,257
Ensembl chr 1:29,191,192...29,201,531
JBrowse link
G Heyl hes-related family bHLH transcription factor with YRPW motif-like ISO UniProtKB:Q9WV93 (MGI:MGI:3783952|PMID:17303760) RGD PMID:17303760 MGI:MGI:3783952 NCBI chr 5:140,923,914...140,940,905
Ensembl chr 5:140,923,914...140,940,905
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha ISO
IEA
MGI:MGI:1857719 (MGI:MGI:1195604|PMID:9436976)
GO_REF:0000107
RGD
Ensembl
PMID:9436976 GO_REF:0000107, MGI:MGI:1195604 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Ilk integrin-linked kinase ISO (MGI:MGI:5619428|PMID:24131868) RGD PMID:24131868 MGI:MGI:5619428 NCBI chr 1:170,578,941...170,585,192
Ensembl chr 1:170,578,889...170,585,189
JBrowse link
G Isl1 ISL LIM homeobox 1 ISO UniProtKB:Q02248 (MGI:MGI:3829137|PMID:17519333) RGD PMID:17519333 MGI:MGI:3829137 NCBI chr 2:48,488,911...48,501,217
Ensembl chr 2:48,487,736...48,501,436
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit ISO MGI:MGI:2149630 (MGI:MGI:1338596|PMID:10352021) RGD PMID:10352021 MGI:MGI:1338596 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Mef2c myocyte enhancer factor 2C ISO
IEA
MGI:MGI:97350 (MGI:MGI:3820390|PMID:19035347)
GO_REF:0000107
RGD
Ensembl
PMID:19035347 GO_REF:0000107, MGI:MGI:3820390 NCBI chr 2:11,658,534...11,822,788
Ensembl chr 2:11,658,568...11,822,787
JBrowse link
G Msx2 msh homeobox 2 ISO MGI:MGI:97168 (MGI:MGI:3720542|PMID:17601530) RGD PMID:17601530 MGI:MGI:3720542 NCBI chr17:11,683,862...11,689,527
Ensembl chr17:11,683,862...11,689,527
JBrowse link
G Nedd4 NEDD4 E3 ubiquitin protein ligase ISO
IEA
MGI:MGI:3799317|MGI:MGI:98737 (MGI:MGI:4452597|PMID:20026598)
GO_REF:0000107
RGD
Ensembl
PMID:20026598 GO_REF:0000107, MGI:MGI:4452597 NCBI chr 8:79,323,408...79,408,842
Ensembl chr 8:79,323,408...79,408,833
JBrowse link
G Nipbl NIPBL, cohesin loading factor ISO (PMID:19242925) RGD PMID:19242925 NCBI chr 2:57,508,830...57,676,197
Ensembl chr 2:57,509,428...57,600,820
JBrowse link
G Nkx2-5 NK2 homeobox 5 ISO MGI:MGI:99458 (MGI:MGI:3773736|PMID:16510504), (MGI:MGI:3820390|PMID:19035347) RGD PMID:16510504, PMID:19035347 MGI:MGI:3773736, MGI:MGI:3820390 NCBI chr10:16,635,989...16,638,758
Ensembl chr10:16,635,989...16,638,764
JBrowse link
G Nog noggin ISO
IEA
(MGI:MGI:3783944|PMID:17218603)
GO_REF:0000107
RGD
Ensembl
PMID:17218603 GO_REF:0000107, MGI:MGI:3783944 NCBI chr10:76,811,759...76,813,386
Ensembl chr10:76,811,759...76,813,386
JBrowse link
G Notch1 notch receptor 1 ISO (PMID:18593716) RGD PMID:18593716 NCBI chr 3:3,905,562...3,951,015
Ensembl chr 3:3,905,453...3,951,025
JBrowse link
G Npy1r neuropeptide Y receptor Y1 ISO
IEA
(PMID:19593212)
GO_REF:0000107
RGD
Ensembl
PMID:19593212 GO_REF:0000107 NCBI chr16:24,779,480...24,789,131
Ensembl chr16:24,779,477...24,788,740
JBrowse link
G Npy2r neuropeptide Y receptor Y2 ISO (PMID:19593212) RGD PMID:19593212 NCBI chr 2:181,528,949...181,538,145
Ensembl chr 2:181,530,832...181,531,978
JBrowse link
G Npy5r neuropeptide Y receptor Y5 ISO (PMID:19593212) RGD PMID:19593212 NCBI chr16:24,796,685...24,805,730
Ensembl chr16:24,797,124...24,805,079
JBrowse link
G Plxnd1 plexin D1 ISO MGI:MGI:5544786 (MGI:MGI:5509072|PMID:23918385) RGD PMID:23918385 MGI:MGI:5509072 NCBI chr 4:147,854,309...147,894,170
Ensembl chr 4:147,854,309...147,893,992
JBrowse link
G Rbpj recombination signal binding protein for immunoglobulin kappa J region ISO (MGI:MGI:3027664|PMID:14701881) RGD PMID:14701881 MGI:MGI:3027664 NCBI chr14:59,657,738...59,865,427
Ensembl chr14:59,658,935...59,735,450
JBrowse link
G Ryr1 ryanodine receptor 1 IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(MGI:MGI:3764002|PMID:18003898)
Ensembl
UniProt
RGD
PMID:18003898 GO_REF:0000024, GO_REF:0000107, MGI:MGI:3764002 NCBI chr 1:87,959,596...88,066,252
Ensembl chr 1:87,959,712...88,066,101
JBrowse link
G Sec24b SEC24 homolog B, COPII coat complex component ISO MGI:MGI:4440621 (MGI:MGI:4439427|PMID:20215345) RGD PMID:20215345 MGI:MGI:4439427 NCBI chr 2:230,286,886...230,356,887
Ensembl chr 2:230,287,296...230,356,919
JBrowse link
G Sema3c semaphorin 3C ISO (PMID:19666519) RGD PMID:19666519 NCBI chr 4:14,318,276...14,490,438
Ensembl chr 4:14,318,274...14,490,446
JBrowse link
G Sfrp2 secreted frizzled-related protein 2 ISO (PMID:19593212) RGD PMID:19593212 NCBI chr 2:182,723,732...182,731,277
Ensembl chr 2:182,723,854...182,731,764
JBrowse link
G Six1 SIX homeobox 1 ISO MGI:MGI:109344|MGI:MGI:98493|MGI:MGI:99604 (MGI:MGI:5002778|PMID:21364285) RGD PMID:21364285 MGI:MGI:5002778 NCBI chr 6:95,929,060...95,934,296
Ensembl chr 6:95,929,060...95,934,296
JBrowse link
G Smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 ISO MGI:MGI:3605892 (MGI:MGI:5469230|PMID:23319608) RGD PMID:23319608 MGI:MGI:5469230 NCBI chr 8:22,648,323...22,739,468
Ensembl chr 8:22,648,323...22,739,468
JBrowse link
G Sox11 SRY-box transcription factor 11 ISO
ISS
(MGI:MGI:3052265|PMID:15254231)
GO_REF:0000024
RGD
UniProt
PMID:15254231 GO_REF:0000024, MGI:MGI:3052265 NCBI chr 6:46,629,967...46,631,988
Ensembl chr 6:46,629,974...46,631,983
JBrowse link
G Sox17 SRY-box transcription factor 17 ISO UniProtKB:P43680 (MGI:MGI:3716256|PMID:17610846) RGD PMID:17610846 MGI:MGI:3716256 NCBI chr 5:14,890,318...14,895,907
Ensembl chr 5:14,890,408...14,895,907
JBrowse link
G Tbx1 T-box transcription factor 1 ISS
ISO
GO_REF:0000024
MGI:MGI:102780|MGI:MGI:109344|MGI:MGI:2179190|MGI:MGI:3664784|MGI:MGI:99604 (MGI:MGI:3770747|PMID:17916582), (MGI:MGI:4353596|PMID:18583714), (MGI:MGI:5002778|PMID:21364285)
UniProt
RGD
PMID:17916582, PMID:18583714, PMID:21364285 GO_REF:0000024, MGI:MGI:3770747, MGI:MGI:4353596, MGI:MGI:5002778 NCBI chr11:86,552,022...86,561,647
Ensembl chr11:86,552,022...86,560,969
JBrowse link
G Tbx2 T-box transcription factor 2 ISO (MGI:MGI:3039059|PMID:15042700), (MGI:MGI:3487212|PMID:15459098) RGD PMID:15042700, PMID:15459098 MGI:MGI:3039059, MGI:MGI:3487212 NCBI chr10:73,278,932...73,290,764
Ensembl chr10:73,279,119...73,289,921
JBrowse link
G Tbx20 T-box transcription factor 20 ISO (MGI:MGI:3604925|PMID:15843409) RGD PMID:15843409 MGI:MGI:3604925 NCBI chr 8:25,849,394...25,904,570
Ensembl chr 8:25,850,962...25,904,570
JBrowse link
G Tbx3 T-box transcription factor 3 ISO MGI:MGI:2655214 (MGI:MGI:4412356|PMID:18723448) RGD PMID:18723448 MGI:MGI:4412356 NCBI chr12:42,479,518...42,494,588
Ensembl chr12:42,480,560...42,492,526
JBrowse link
G Tfap2a transcription factor AP-2 alpha ISO MGI:MGI:2176682 (MGI:MGI:2156913|PMID:11744375) RGD PMID:11744375 MGI:MGI:2156913 NCBI chr17:24,653,342...24,670,457
Ensembl chr17:24,654,902...24,670,457
JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 ISO (MGI:MGI:3801267|PMID:17050629) RGD PMID:17050629 MGI:MGI:3801267 NCBI chr 8:124,310,288...124,399,345
Ensembl chr 8:124,312,754...124,399,494
JBrowse link
G Tgfbr3 transforming growth factor beta receptor 3 ISO (MGI:MGI:3818140|PMID:17704211) RGD PMID:17704211 MGI:MGI:3818140 NCBI chr14:3,506,416...3,680,508
Ensembl chr14:3,506,339...3,682,545
JBrowse link
G Thbs1 thrombospondin 1 ISO MGI:MGI:97297 (MGI:MGI:4452597|PMID:20026598) RGD PMID:20026598 MGI:MGI:4452597 NCBI chr 3:109,862,120...109,873,466
Ensembl chr 3:109,862,117...109,873,466
JBrowse link
G Vegfa vascular endothelial growth factor A ISO (MGI:MGI:4461879|PMID:18093989) RGD PMID:18093989 MGI:MGI:4461879 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
G Wnt11 Wnt family member 11 ISO MGI:MGI:2665014 (MGI:MGI:3759355|PMID:17767158) RGD PMID:17767158 MGI:MGI:3759355 NCBI chr 1:163,794,136...163,813,756
Ensembl chr 1:163,797,660...163,813,756
JBrowse link
G Zfpm1 zinc finger protein, multitype 1 ISO (MGI:MGI:3583527|PMID:14614148) RGD PMID:14614148 MGI:MGI:3583527 NCBI chr19:55,094,585...55,150,994
Ensembl chr19:55,094,585...55,150,686
JBrowse link
canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctnnb1 catenin beta 1 ISO
IEA
(MGI:MGI:2446944|PMID:12464179)
GO_REF:0000107
RGD
Ensembl
PMID:12464179 GO_REF:0000107, MGI:MGI:2446944 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372
JBrowse link
G Lrp6 LDL receptor related protein 6 ISO MGI:MGI:2156191 (MGI:MGI:4413394|PMID:19705442) RGD PMID:19705442 MGI:MGI:4413394 NCBI chr 4:168,194,054...168,323,962
Ensembl chr 4:168,194,927...168,323,751
JBrowse link
cardiac neural crest cell development involved in outflow tract morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dicer1 dicer 1 ribonuclease III ISO MGI:MGI:3589208 (MGI:MGI:4849577|PMID:21098571) RGD PMID:21098571 MGI:MGI:4849577 NCBI chr 6:128,388,084...128,453,234
Ensembl chr 6:128,388,053...128,434,183
JBrowse link
G Hand2 heart and neural crest derivatives expressed 2 ISO (MGI:MGI:4413411|PMID:19008477) RGD PMID:19008477 MGI:MGI:4413411 NCBI chr16:36,371,489...36,373,551
Ensembl chr16:36,371,489...36,373,546
JBrowse link
G Hes1 hes family bHLH transcription factor 1 ISO
IEA
(MGI:MGI:4354447|PMID:19609448)
GO_REF:0000107
RGD
Ensembl
PMID:19609448 GO_REF:0000107, MGI:MGI:4354447 NCBI chr11:74,312,837...74,315,249
Ensembl chr11:74,312,806...74,315,248
JBrowse link
G Jag1 jagged canonical Notch ligand 1 ISO
IEA
(MGI:MGI:4359139|PMID:19509466)
GO_REF:0000107
RGD
Ensembl
PMID:19509466 GO_REF:0000107, MGI:MGI:4359139 NCBI chr 3:130,079,361...130,114,781
Ensembl chr 3:130,079,361...130,114,770
JBrowse link
G Twist1 twist family bHLH transcription factor 1 ISO MGI:MGI:1857265 (MGI:MGI:3805126|PMID:18539270) RGD PMID:18539270 MGI:MGI:3805126 NCBI chr 6:53,401,241...53,403,235
Ensembl chr 6:53,401,109...53,403,214
JBrowse link
cardiac neural crest cell migration involved in outflow tract morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Folr1 folate receptor alpha ISO (MGI:MGI:3721767|PMID:17286298) RGD PMID:17286298 MGI:MGI:3721767 NCBI chr 1:166,934,457...166,945,864
Ensembl chr 1:166,934,460...166,943,592
JBrowse link
G Hand2 heart and neural crest derivatives expressed 2 ISO
IEA
MGI:MGI:2386570|MGI:MGI:3803647 (MGI:MGI:4453274|PMID:20144608)
GO_REF:0000107
RGD
Ensembl
PMID:20144608 GO_REF:0000107, MGI:MGI:4453274 NCBI chr16:36,371,489...36,373,551
Ensembl chr16:36,371,489...36,373,546
JBrowse link
G Nrp1 neuropilin 1 NOT ISO (MGI:MGI:5693177|PMID:26053665) RGD PMID:26053665 MGI:MGI:5693177 NCBI chr19:61,332,351...61,486,166
Ensembl chr19:61,332,351...61,485,858
JBrowse link
G Pitx2 paired-like homeodomain 2 ISO (MGI:MGI:2446944|PMID:12464179) RGD PMID:12464179 MGI:MGI:2446944 NCBI chr 2:233,602,732...233,621,059
Ensembl chr 2:233,602,732...233,621,129
JBrowse link
G Twist1 twist family bHLH transcription factor 1 ISO MGI:MGI:1857265 (MGI:MGI:3805126|PMID:18539270) RGD PMID:18539270 MGI:MGI:3805126 NCBI chr 6:53,401,241...53,403,235
Ensembl chr 6:53,401,109...53,403,214
JBrowse link
cell proliferation involved in outflow tract morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hand2 heart and neural crest derivatives expressed 2 ISO
IEA
MGI:MGI:2386570|MGI:MGI:3803647 (MGI:MGI:4453274|PMID:20144608)
GO_REF:0000107
RGD
Ensembl
PMID:20144608 GO_REF:0000107, MGI:MGI:4453274 NCBI chr16:36,371,489...36,373,551
Ensembl chr16:36,371,489...36,373,546
JBrowse link
G Pitx2 paired-like homeodomain 2 ISO MGI:MGI:1857844|MGI:MGI:2445429 (MGI:MGI:2446944|PMID:12464179), (MGI:MGI:3701739|PMID:16836994) RGD PMID:12464179, PMID:16836994 MGI:MGI:2446944, MGI:MGI:3701739 NCBI chr 2:233,602,732...233,621,059
Ensembl chr 2:233,602,732...233,621,129
JBrowse link
negative regulation of apoptotic process involved in outflow tract morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxc1 forkhead box C1 ISO MGI:MGI:1347481 (MGI:MGI:3701735|PMID:16839542) RGD PMID:16839542 MGI:MGI:3701735 NCBI chr17:33,947,501...33,951,484
Ensembl chr17:33,947,506...33,951,484
JBrowse link
G Foxc2 forkhead box C2 ISO MGI:MGI:1347466 (MGI:MGI:3701735|PMID:16839542) RGD PMID:16839542 MGI:MGI:3701735 NCBI chr19:53,044,379...53,047,081
Ensembl chr19:53,044,379...53,047,081
JBrowse link
negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lrp6 LDL receptor related protein 6 ISO MGI:MGI:98958 (MGI:MGI:4830282|PMID:19056682) RGD PMID:19056682 MGI:MGI:4830282 NCBI chr 4:168,194,054...168,323,962
Ensembl chr 4:168,194,927...168,323,751
JBrowse link
outflow tract septum morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr1 activin A receptor type 1 NOT ISO (MGI:MGI:3610266|PMID:16140292) RGD PMID:16140292 MGI:MGI:3610266 NCBI chr 3:44,432,476...44,539,680
Ensembl chr 3:44,432,471...44,522,930
JBrowse link
G Bmp4 bone morphogenetic protein 4 IEA
ISO
GO_REF:0000107
(MGI:MGI:3039210|PMID:15070745), (MGI:MGI:3814273|PMID:18924235)
Ensembl
RGD
PMID:15070745, PMID:18924235 GO_REF:0000107, MGI:MGI:3039210, MGI:MGI:3814273 NCBI chr15:20,776,060...20,791,013
Ensembl chr15:20,776,054...20,822,740
JBrowse link
G Bmpr1a bone morphogenetic protein receptor type 1A ISO (MGI:MGI:3040576|PMID:15073157) RGD PMID:15073157 MGI:MGI:3040576 NCBI chr16:10,758,278...10,852,170
Ensembl chr16:10,758,527...10,802,512
JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 NOT ISO (MGI:MGI:2429424|PMID:12441304)
(MGI:MGI:3851675|PMID:19409885)
RGD PMID:12441304, PMID:19409885 MGI:MGI:2429424, MGI:MGI:3851675 NCBI chr 9:66,568,074...66,683,019
Ensembl chr 9:66,568,074...66,676,494
JBrowse link
G Dvl3 dishevelled segment polarity protein 3 ISO MGI:MGI:3831892 (MGI:MGI:3821448|PMID:19008950) RGD PMID:19008950 MGI:MGI:3821448 NCBI chr11:84,051,177...84,068,479
Ensembl chr11:84,051,078...84,068,302
JBrowse link
G Eng endoglin ISO UniProtKB:P97471 (MGI:MGI:3721185|PMID:17628518) RGD PMID:17628518 MGI:MGI:3721185 NCBI chr 3:11,679,530...11,717,486
Ensembl chr 3:11,679,530...11,717,485
JBrowse link
G Fgf8 fibroblast growth factor 8 ISO
ISS
UniProtKB:P70323 (MGI:MGI:5285152|PMID:20807544)
GO_REF:0000024
RGD
UniProt
PMID:20807544 GO_REF:0000024, MGI:MGI:5285152 NCBI chr 1:265,492,949...265,498,965
Ensembl chr 1:265,493,124...265,498,831
JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 ISO MGI:MGI:2153818 (MGI:MGI:3653131|PMID:16687131) RGD PMID:16687131 MGI:MGI:3653131 NCBI chr 1:200,590,951...200,696,946
Ensembl chr 1:200,590,953...200,696,928
JBrowse link
G Gata6 GATA binding protein 6 ISO
IEA
(PMID:19666519)
GO_REF:0000107
RGD
Ensembl
PMID:19666519 GO_REF:0000107 NCBI chr18:2,415,821...2,447,087
Ensembl chr18:2,416,552...2,446,338
JBrowse link
G Isl1 ISL LIM homeobox 1 ISO UniProtKB:Q02248 (MGI:MGI:3829137|PMID:17519333) RGD PMID:17519333 MGI:MGI:3829137 NCBI chr 2:48,488,911...48,501,217
Ensembl chr 2:48,487,736...48,501,436
JBrowse link
G Lrp2 LDL receptor related protein 2 IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(MGI:MGI:5770180|PMID:26822476)
Ensembl
UniProt
RGD
PMID:26822476 GO_REF:0000024, GO_REF:0000107, MGI:MGI:5770180 NCBI chr 3:55,665,153...55,822,484
Ensembl chr 3:55,665,145...55,822,551
JBrowse link
G Msx2 msh homeobox 2 ISO
IEA
MGI:MGI:97168 (MGI:MGI:3720542|PMID:17601530)
GO_REF:0000107
RGD
Ensembl
PMID:17601530 GO_REF:0000107, MGI:MGI:3720542 NCBI chr17:11,683,862...11,689,527
Ensembl chr17:11,683,862...11,689,527
JBrowse link
G Nkx2-5 NK2 homeobox 5 ISO
IEA
(PMID:20807224)
GO_REF:0000107
RGD
Ensembl
PMID:20807224 GO_REF:0000107 NCBI chr10:16,635,989...16,638,758
Ensembl chr10:16,635,989...16,638,764
JBrowse link
G Nrp1 neuropilin 1 ISO (MGI:MGI:5693177|PMID:26053665) RGD PMID:26053665 MGI:MGI:5693177 NCBI chr19:61,332,351...61,486,166
Ensembl chr19:61,332,351...61,485,858
JBrowse link
G Nrp2 neuropilin 2 ISO UniProtKB:Q62181 (MGI:MGI:5693177|PMID:26053665) RGD PMID:26053665 MGI:MGI:5693177 NCBI chr 9:69,496,875...69,609,802
Ensembl chr 9:69,497,121...69,612,087
JBrowse link
G Parva parvin, alpha IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(MGI:MGI:4368016|PMID:19798050)
Ensembl
UniProt
RGD
PMID:19798050 GO_REF:0000024, GO_REF:0000107, MGI:MGI:4368016 NCBI chr 1:177,249,302...177,408,160
Ensembl chr 1:177,249,226...177,408,205
JBrowse link
G Rara retinoic acid receptor, alpha ISO MGI:MGI:97857 (MGI:MGI:1270092|PMID:9659935) RGD PMID:9659935 MGI:MGI:1270092 NCBI chr10:86,838,819...86,884,224
Ensembl chr10:86,860,685...86,884,210
JBrowse link
G Rarb retinoic acid receptor, beta ISO MGI:MGI:97856 (MGI:MGI:1270092|PMID:9659935) RGD PMID:9659935 MGI:MGI:1270092 NCBI chr15:9,915,223...10,262,599
Ensembl chr15:10,120,206...10,262,599
JBrowse link
G Robo1 roundabout guidance receptor 1 ISO UniProtKB:Q7TPD3 (MGI:MGI:5913048|PMID:25691540) RGD PMID:25691540 MGI:MGI:5913048 NCBI chr11:9,079,291...10,146,302
Ensembl chr11:9,642,365...10,143,317
JBrowse link
G Robo2 roundabout guidance receptor 2 ISO UniProtKB:O89026 (MGI:MGI:5913048|PMID:25691540) RGD PMID:25691540 MGI:MGI:5913048 NCBI chr11:11,062,866...12,618,793
Ensembl chr11:11,062,790...11,585,765
JBrowse link
G Sema3c semaphorin 3C ISO UniProtKB:O35375|UniProtKB:P97333 (MGI:MGI:5693177|PMID:26053665) RGD PMID:26053665 MGI:MGI:5693177 NCBI chr 4:14,318,276...14,490,438
Ensembl chr 4:14,318,274...14,490,446
JBrowse link
G Smad4 SMAD family member 4 ISO
IEA
UniProtKB:Q63961 (MGI:MGI:3721185|PMID:17628518)
GO_REF:0000107
RGD
Ensembl
PMID:17628518 GO_REF:0000107, MGI:MGI:3721185 NCBI chr18:69,626,682...69,657,373
Ensembl chr18:69,627,757...69,671,199
JBrowse link
G Smad6 SMAD family member 6 ISO (MGI:MGI:1352979|PMID:10655064) RGD PMID:10655064 MGI:MGI:1352979 NCBI chr 8:68,897,746...68,967,221
Ensembl chr 8:68,898,296...68,966,108
JBrowse link
G Tbx1 T-box transcription factor 1 ISO
ISS
(MGI:MGI:5285152|PMID:20807544)
GO_REF:0000024
RGD
UniProt
PMID:20807544 GO_REF:0000024, MGI:MGI:5285152 NCBI chr11:86,552,022...86,561,647
Ensembl chr11:86,552,022...86,560,969
JBrowse link
G Tbx2 T-box transcription factor 2 ISO (MGI:MGI:3487212|PMID:15459098) RGD PMID:15459098 MGI:MGI:3487212 NCBI chr10:73,278,932...73,290,764
Ensembl chr10:73,279,119...73,289,921
JBrowse link
G Tbx20 T-box transcription factor 20 ISO (MGI:MGI:3604925|PMID:15843409)
(PMID:18275040), (PMID:18834961)
RGD PMID:15843409, PMID:18275040, PMID:18834961 MGI:MGI:3604925 NCBI chr 8:25,849,394...25,904,570
Ensembl chr 8:25,850,962...25,904,570
JBrowse link
G Tgfb2 transforming growth factor, beta 2 ISO (MGI:MGI:3609313|PMID:11390347), (MGI:MGI:894212|PMID:9217007) RGD PMID:9217007, PMID:11390347 MGI:MGI:3609313, MGI:MGI:894212 NCBI chr13:105,039,639...105,142,010
Ensembl chr13:105,039,853...105,141,030
JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 ISO (MGI:MGI:4821522|PMID:20652948) RGD PMID:20652948 MGI:MGI:4821522 NCBI chr 8:124,310,288...124,399,345
Ensembl chr 8:124,312,754...124,399,494
JBrowse link
G Zfpm2 zinc finger protein, multitype 2 ISO (PMID:20807224) RGD PMID:20807224 NCBI chr 7:79,471,277...79,964,405
Ensembl chr 7:79,638,046...79,964,405
JBrowse link
planar cell polarity pathway involved in outflow tract morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wnt5a Wnt family member 5A ISO
IEA
MGI:MGI:1857617 (MGI:MGI:4830282|PMID:19056682)
GO_REF:0000107
RGD
Ensembl
PMID:19056682 GO_REF:0000107, MGI:MGI:4830282 NCBI chr16:4,469,451...4,490,271
Ensembl chr16:4,469,468...4,489,860
JBrowse link
positive regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 IEA
ISO
GO_REF:0000107
UniProtKB:P23359 (MGI:MGI:5502250|PMID:23863481)
Ensembl
RGD
PMID:23863481 GO_REF:0000107, MGI:MGI:5502250 NCBI chr15:20,776,060...20,791,013
Ensembl chr15:20,776,054...20,822,740
JBrowse link
G Bmp7 bone morphogenetic protein 7 ISO UniProtKB:P21275 (MGI:MGI:5502250|PMID:23863481) RGD PMID:23863481 MGI:MGI:5502250 NCBI chr 3:170,879,972...170,955,820
Ensembl chr 3:170,879,973...170,955,399
JBrowse link
G Sema3c semaphorin 3C ISO (MGI:MGI:5693177|PMID:26053665) RGD PMID:26053665 MGI:MGI:5693177 NCBI chr 4:14,318,276...14,490,438
Ensembl chr 4:14,318,274...14,490,446
JBrowse link
positive regulation of cell proliferation involved in outflow tract morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 ISO
IEA
(MGI:MGI:3039210|PMID:15070745)
GO_REF:0000107
RGD
Ensembl
PMID:15070745 GO_REF:0000107, MGI:MGI:3039210 NCBI chr15:20,776,060...20,791,013
Ensembl chr15:20,776,054...20,822,740
JBrowse link
positive regulation of semaphorin-plexin signaling pathway involved in outflow tract morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hand2 heart and neural crest derivatives expressed 2 ISO
IEA
(MGI:MGI:4413411|PMID:19008477)
GO_REF:0000107
RGD
Ensembl
PMID:19008477 GO_REF:0000107, MGI:MGI:4413411 NCBI chr16:36,371,489...36,373,551
Ensembl chr16:36,371,489...36,373,546
JBrowse link
regulation of apoptotic process involved in outflow tract morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tgfb2 transforming growth factor, beta 2 ISO (MGI:MGI:3609313|PMID:11390347) RGD PMID:11390347 MGI:MGI:3609313 NCBI chr13:105,039,639...105,142,010
Ensembl chr13:105,039,853...105,141,030
JBrowse link
regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eng endoglin NOT ISO (MGI:MGI:3721185|PMID:17628518) RGD PMID:17628518 MGI:MGI:3721185 NCBI chr 3:11,679,530...11,717,486
Ensembl chr 3:11,679,530...11,717,485
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20027
    developmental process 6827
      anatomical structure morphogenesis 2877
        outflow tract morphogenesis 83
          apoptotic process involved in outflow tract morphogenesis + 3
          cardiac neural crest cell delamination involved in outflow tract morphogenesis 0
          cardiac neural crest cell development involved in outflow tract morphogenesis + 12
          cell proliferation involved in outflow tract morphogenesis + 5
          outflow tract septum morphogenesis 29
          planar cell polarity pathway involved in outflow tract morphogenesis + 2
          semaphorin-plexin signaling pathway involved in outflow tract morphogenesis + 1
Path 2
Term Annotations click to browse term
  biological_process 20027
    developmental process 6827
      anatomical structure development 6269
        multicellular organism development 5744
          system development 5280
            circulatory system development 1224
              heart development 687
                heart morphogenesis 280
                  outflow tract morphogenesis 83
                    apoptotic process involved in outflow tract morphogenesis + 3
                    cardiac neural crest cell delamination involved in outflow tract morphogenesis 0
                    cardiac neural crest cell development involved in outflow tract morphogenesis + 12
                    cell proliferation involved in outflow tract morphogenesis + 5
                    outflow tract septum morphogenesis 29
                    planar cell polarity pathway involved in outflow tract morphogenesis + 2
                    semaphorin-plexin signaling pathway involved in outflow tract morphogenesis + 1
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.