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ONTOLOGY REPORT - ANNOTATIONS


Term:endocardium development
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Accession:GO:0003157 term browser browse the term
Definition:The process whose specific outcome is the progression of the endocardium over time, from its formation to the mature structure. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers.


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endocardium development term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kdr kinase insert domain receptor ISO (MGI:MGI:74276|PMID:7596435) RGD PMID:7596435 MGI:MGI:74276 NCBI chr14:34,727,677...34,787,127
Ensembl chr14:34,727,623...34,787,183
JBrowse link
G Notch1 notch receptor 1 ISO (MGI:MGI:3701380|PMID:17336907) RGD PMID:17336907 MGI:MGI:3701380 NCBI chr 3:3,905,562...3,951,015
Ensembl chr 3:3,905,453...3,951,025
JBrowse link
G Rbpj recombination signal binding protein for immunoglobulin kappa J region ISO (MGI:MGI:3701380|PMID:17336907) RGD PMID:17336907 MGI:MGI:3701380 NCBI chr14:59,657,738...59,865,427
Ensembl chr14:59,658,935...59,735,450
JBrowse link
G Stk3 serine/threonine kinase 3 ISO
IEA
MGI:MGI:1929004 (MGI:MGI:4412133|PMID:19786569)
GO_REF:0000107
RGD
Ensembl
PMID:19786569 GO_REF:0000107, MGI:MGI:4412133 NCBI chr 7:73,617,926...73,883,896
Ensembl chr 7:73,618,644...73,883,812
JBrowse link
G Stk4 serine/threonine kinase 4 ISO MGI:MGI:1928487 (MGI:MGI:4412133|PMID:19786569) RGD PMID:19786569 MGI:MGI:4412133 NCBI chr 3:160,467,552...160,546,540
Ensembl chr 3:160,467,552...160,546,540
JBrowse link
endocardial cell differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Notch1 notch receptor 1 ISO (MGI:MGI:4837019|PMID:20890042) RGD PMID:20890042 MGI:MGI:4837019 NCBI chr 3:3,905,562...3,951,015
Ensembl chr 3:3,905,453...3,951,025
JBrowse link
G Nrg1 neuregulin 1 ISO
IEA
(PMID:17336907)
GO_REF:0000107
RGD
Ensembl
PMID:17336907 GO_REF:0000107 NCBI chr16:62,969,573...64,065,063
Ensembl chr16:63,837,216...64,057,434
JBrowse link
G Smad4 SMAD family member 4 ISO
IEA
(MGI:MGI:4946551|PMID:21330551)
GO_REF:0000107
RGD
Ensembl
PMID:21330551 GO_REF:0000107, MGI:MGI:4946551 NCBI chr18:69,626,682...69,657,373
Ensembl chr18:69,627,757...69,671,199
JBrowse link
G Sox17 SRY-box transcription factor 17 ISO MGI:MGI:103559 (MGI:MGI:3716256|PMID:17610846) RGD PMID:17610846 MGI:MGI:3716256 NCBI chr 5:14,890,318...14,895,907
Ensembl chr 5:14,890,408...14,895,907
JBrowse link
G Sox18 SRY-box transcription factor 18 ISO MGI:MGI:107543 (MGI:MGI:3716256|PMID:17610846) RGD PMID:17610846 MGI:MGI:3716256 NCBI chr 3:177,177,237...177,179,039
Ensembl chr 3:177,177,310...177,179,127
JBrowse link
endocardial cushion cell fate commitment term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr1 activin A receptor type 1 ISO
IEA
(PMID:19506109)
GO_REF:0000107
RGD
Ensembl
PMID:19506109 GO_REF:0000107 NCBI chr 3:44,432,476...44,539,680
Ensembl chr 3:44,432,471...44,522,930
JBrowse link
endocardium formation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ovol2 ovo-like zinc finger 2 ISO MGI:MGI:3777011 (MGI:MGI:3776202|PMID:17573777) RGD PMID:17573777 MGI:MGI:3776202 NCBI chr 3:138,433,990...138,464,511
Ensembl chr 3:138,433,990...138,462,063
JBrowse link
G Prox1 prospero homeobox 1 ISO (MGI:MGI:3830437|PMID:19091769) RGD PMID:19091769 MGI:MGI:3830437 NCBI chr13:108,382,536...108,444,107
Ensembl chr13:108,382,399...108,443,294
JBrowse link
G Sox17 SRY-box transcription factor 17 ISO MGI:MGI:103559 (MGI:MGI:3716256|PMID:17610846) RGD PMID:17610846 MGI:MGI:3716256 NCBI chr 5:14,890,318...14,895,907
Ensembl chr 5:14,890,408...14,895,907
JBrowse link
G Sox18 SRY-box transcription factor 18 ISO MGI:MGI:107543 (MGI:MGI:3716256|PMID:17610846) RGD PMID:17610846 MGI:MGI:3716256 NCBI chr 3:177,177,237...177,179,039
Ensembl chr 3:177,177,310...177,179,127
JBrowse link
endocardium morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Notch1 notch receptor 1 ISO (MGI:MGI:4837019|PMID:20890042), (PMID:16025100) RGD PMID:16025100, PMID:20890042 MGI:MGI:4837019 NCBI chr 3:3,905,562...3,951,015
Ensembl chr 3:3,905,453...3,951,025
JBrowse link
G Rbpj recombination signal binding protein for immunoglobulin kappa J region ISO (MGI:MGI:3027664|PMID:14701881) RGD PMID:14701881 MGI:MGI:3027664 NCBI chr14:59,657,738...59,865,427
Ensembl chr14:59,658,935...59,735,450
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20014
    developmental process 6812
      anatomical structure development 6256
        endocardium development 12
          endocardial cell differentiation + 6
          endocardial endothelium development 0
          endocardium morphogenesis + 6
          extracellular matrix organization involved in endocardium development 0
Path 2
Term Annotations click to browse term
  biological_process 20014
    developmental process 6812
      anatomical structure development 6256
        multicellular organism development 5735
          system development 5272
            animal organ development 4027
              heart development 687
                endocardium development 12
                  endocardial cell differentiation + 6
                  endocardial endothelium development 0
                  endocardium morphogenesis + 6
                  extracellular matrix organization involved in endocardium development 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.