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ONTOLOGY REPORT - ANNOTATIONS


Term:aortic valve development
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Accession:GO:0003176 term browser browse the term
Definition:The progression of the aortic valve over time, from its formation to the mature structure.


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aortic valve development term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp2 bone morphogenetic protein 2 ISO (MGI:MGI:3640731|PMID:16730346) RGD PMID:16730346 MGI:MGI:3640731 NCBI chr 3:126,335,963...126,346,771
Ensembl chr 3:126,335,863...126,346,318
JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 ISO GO:1905314 (MGI:MGI:2429424|PMID:12441304) RGD PMID:12441304 MGI:MGI:2429424 NCBI chr 9:66,568,074...66,683,019
Ensembl chr 9:66,568,074...66,676,494
JBrowse link
G Nfatc1 nuclear factor of activated T-cells 1 ISO (MGI:MGI:5319103|PMID:22300732) RGD PMID:22300732 MGI:MGI:5319103 NCBI chr18:77,203,517...77,322,690
Ensembl chr18:77,203,525...77,322,690
JBrowse link
G Rbpj recombination signal binding protein for immunoglobulin kappa J region ISO (MGI:MGI:6158728|PMID:26491108) RGD PMID:26491108 MGI:MGI:6158728 NCBI chr14:59,657,738...59,865,427
Ensembl chr14:59,658,935...59,735,450
JBrowse link
G Tbx20 T-box transcription factor 20 ISO (MGI:MGI:3604925|PMID:15843409) RGD PMID:15843409 MGI:MGI:3604925 NCBI chr 8:25,849,394...25,904,570
Ensembl chr 8:25,850,962...25,904,570
JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A ISO
IEA
UniProtKB:P25119 (MGI:MGI:6158728|PMID:26491108)
GO_REF:0000107
RGD
Ensembl
PMID:26491108 GO_REF:0000107, MGI:MGI:6158728 NCBI chr 4:157,864,905...157,877,634
Ensembl chr 4:157,864,969...157,877,633
JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B ISO UniProtKB:P25118 (MGI:MGI:6158728|PMID:26491108) RGD PMID:26491108 MGI:MGI:6158728 NCBI chr 5:163,136,390...163,167,299
Ensembl chr 5:163,136,390...163,167,299
JBrowse link
aortic valve morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 IEA
ISO
GO_REF:0000107
(MGI:MGI:3039210|PMID:15070745), (MGI:MGI:3814273|PMID:18924235)
Ensembl
RGD
PMID:15070745, PMID:18924235 GO_REF:0000107, MGI:MGI:3039210, MGI:MGI:3814273 NCBI chr15:20,776,060...20,791,013
Ensembl chr15:20,776,054...20,822,740
JBrowse link
G Efna1 ephrin A1 ISO (MGI:MGI:4847981|PMID:20960543) RGD PMID:20960543 MGI:MGI:4847981 NCBI chr 2:188,588,808...188,596,156
Ensembl chr 2:188,588,796...188,596,222
JBrowse link
G Emilin1 elastin microfibril interfacer 1 ISO (MGI:MGI:5605894|PMID:25056700) RGD PMID:25056700 MGI:MGI:5605894 NCBI chr 6:26,821,249...26,829,013
Ensembl chr 6:26,821,255...26,828,972
JBrowse link
G Gata3 GATA binding protein 3 ISO
ISS
(MGI:MGI:3832106|PMID:18955134)
GO_REF:0000024
RGD
UniProt
PMID:18955134 GO_REF:0000024, MGI:MGI:3832106 NCBI chr17:72,419,752...72,452,043
Ensembl chr17:72,429,618...72,450,681
JBrowse link
G Gata4 GATA binding protein 4 ISO (PMID:29325903) RGD PMID:29325903 NCBI chr15:46,386,703...46,458,679
Ensembl chr15:46,386,712...46,432,965
JBrowse link
G Gata5 GATA binding protein 5 ISO (PMID:22641149), (PMID:24638895)
(MGI:MGI:5286818|PMID:21633169)
RGD PMID:21633169, PMID:22641149, PMID:24638895 MGI:MGI:5286818 NCBI chr 3:175,701,278...175,709,465
Ensembl chr 3:175,701,280...175,709,465
JBrowse link
G Nfatc1 nuclear factor of activated T-cells 1 ISO MGI:MGI:2181762 (MGI:MGI:1197815|PMID:9515964) RGD PMID:9515964 MGI:MGI:1197815 NCBI chr18:77,203,517...77,322,690
Ensembl chr18:77,203,525...77,322,690
JBrowse link
G Nos3 nitric oxide synthase 3 IEA
ISO
GO_REF:0000107
UniProtKB:Q01705 (MGI:MGI:3609262|PMID:10821808), (MGI:MGI:6158784|PMID:27107132), (MGI:MGI:6158885|PMID:23583836)
Ensembl
RGD
PMID:10821808, PMID:23583836, PMID:27107132 GO_REF:0000107, MGI:MGI:3609262, MGI:MGI:6158784, MGI:MGI:6158885 NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410
JBrowse link
G Notch1 notch receptor 1 ISO (PMID:16025100), (PMID:17662764), (PMID:18593716)
UniProtKB:P70313 (MGI:MGI:6158728|PMID:26491108), (MGI:MGI:6158784|PMID:27107132), (MGI:MGI:6158885|PMID:23583836)
RGD PMID:16025100, PMID:17662764, PMID:18593716, PMID:23583836, PMID:26491108, PMID:27107132 MGI:MGI:6158728, MGI:MGI:6158784, MGI:MGI:6158885 NCBI chr 3:3,905,562...3,951,015
Ensembl chr 3:3,905,453...3,951,025
JBrowse link
G Rb1 RB transcriptional corepressor 1 IEA
ISO
GO_REF:0000107
(MGI:MGI:6112863|PMID:29304157)
Ensembl
RGD
PMID:29304157 GO_REF:0000107, MGI:MGI:6112863 NCBI chr15:55,081,582...55,209,060
Ensembl chr15:55,083,140...55,209,342
JBrowse link
G Robo1 roundabout guidance receptor 1 ISO UniProtKB:Q7TPD3 (MGI:MGI:5913048|PMID:25691540) RGD PMID:25691540 MGI:MGI:5913048 NCBI chr11:9,079,291...10,146,302
Ensembl chr11:9,642,365...10,143,317
JBrowse link
G Robo2 roundabout guidance receptor 2 ISO UniProtKB:O89026 (MGI:MGI:5913048|PMID:25691540) RGD PMID:25691540 MGI:MGI:5913048 NCBI chr11:11,062,866...12,618,793
Ensembl chr11:11,062,790...11,585,765
JBrowse link
G Rock1 Rho-associated coiled-coil containing protein kinase 1 ISO UniProtKB:M3TYT0 (PMID:26634652) RGD PMID:26634652 NCBI chr18:1,273,490...1,390,790
Ensembl chr18:1,273,453...1,390,190
JBrowse link
G Rock2 Rho-associated coiled-coil containing protein kinase 2 ISO UniProtKB:I3LFH3 (PMID:26634652) RGD PMID:26634652 NCBI chr 6:42,180,864...42,289,910
Ensembl chr 6:42,180,894...42,289,908
JBrowse link
G Slit2 slit guidance ligand 2 ISO (MGI:MGI:5913048|PMID:25691540) RGD PMID:25691540 MGI:MGI:5913048 NCBI chr14:66,831,848...67,171,491
Ensembl chr14:66,831,848...67,170,361
JBrowse link
G Slit3 slit guidance ligand 3 IEA
ISO
GO_REF:0000107
(MGI:MGI:5913048|PMID:25691540)
Ensembl
RGD
PMID:25691540 GO_REF:0000107, MGI:MGI:5913048 NCBI chr10:19,924,200...20,517,918
Ensembl chr10:20,320,878...20,518,518
JBrowse link
G Smad6 SMAD family member 6 ISO (PMID:22275001) RGD PMID:22275001 NCBI chr 8:68,897,746...68,967,221
Ensembl chr 8:68,898,296...68,966,108
JBrowse link
G Sox9 SRY-box transcription factor 9 ISO (PMID:22110751) RGD PMID:22110751 NCBI chr10:101,288,528...101,294,030
Ensembl chr10:101,288,489...101,293,379
JBrowse link
G Tbx20 T-box transcription factor 20 ISO (PMID:18275040), (PMID:18834961) RGD PMID:18275040, PMID:18834961 NCBI chr 8:25,849,394...25,904,570
Ensembl chr 8:25,850,962...25,904,570
JBrowse link
G Tgfb1 transforming growth factor, beta 1 ISO (PMID:26634652)
(MGI:MGI:5921830|PMID:26634652)
RGD PMID:26634652 MGI:MGI:5921830 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Twist1 twist family bHLH transcription factor 1 ISO (MGI:MGI:4838344|PMID:20804746)
(PMID:20804746)
RGD PMID:20804746 MGI:MGI:4838344 NCBI chr 6:53,401,241...53,403,235
Ensembl chr 6:53,401,109...53,403,214
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20027
    developmental process 6827
      anatomical structure development 6269
        heart valve development 59
          semi-lunar valve development 34
            aortic valve development 26
              aortic valve morphogenesis + 21
Path 2
Term Annotations click to browse term
  biological_process 20027
    developmental process 6827
      anatomical structure development 6269
        multicellular organism development 5744
          system development 5280
            animal organ development 4035
              heart development 687
                heart valve development 59
                  semi-lunar valve development 34
                    aortic valve development 26
                      aortic valve morphogenesis + 21
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.