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Term:aortic valve morphogenesis
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Accession:GO:0003180 term browser browse the term
Definition:The process in which the structure of the aortic valve is generated and organized.

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aortic valve morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 ISO (MGI:MGI:3039210|PMID:15070745), (MGI:MGI:3814273|PMID:18924235) BHF-UCL PMID:15070745, PMID:18924235 MGI:MGI:3039210, MGI:MGI:3814273 NCBI chrNW_004955409:9,432,835...9,439,680
Ensembl chrNW_004955409:9,432,841...9,440,303
JBrowse link
G Efna1 ephrin A1 ISO (MGI:MGI:4847981|PMID:20960543) BHF-UCL PMID:20960543 MGI:MGI:4847981 NCBI chrNW_004955545:1,610,929...1,617,217
Ensembl chrNW_004955545:1,610,929...1,617,460
JBrowse link
G Emilin1 elastin microfibril interfacer 1 ISO (MGI:MGI:5605894|PMID:25056700) BHF-UCL PMID:25056700 MGI:MGI:5605894 NCBI chrNW_004955469:9,049,666...9,057,692
Ensembl chrNW_004955469:9,049,662...9,057,684
JBrowse link
G Gata3 GATA binding protein 3 ISO (MGI:MGI:3832106|PMID:18955134) UniProtKB PMID:18955134 MGI:MGI:3832106 NCBI chrNW_004955421:24,448,446...24,477,885
Ensembl chrNW_004955421:24,457,496...24,478,744
JBrowse link
G Gata4 GATA binding protein 4 ISO (PMID:29325903) BHF-UCL PMID:29325903 NCBI chrNW_004955403:52,958,318...53,029,267
Ensembl chrNW_004955403:52,987,644...53,029,267
JBrowse link
G Gata5 GATA binding protein 5 ISO (MGI:MGI:5286818|PMID:21633169)
(PMID:22641149), (PMID:24638895)
BHF-UCL PMID:21633169, PMID:22641149, PMID:24638895 MGI:MGI:5286818 NCBI chrNW_004955528:1,595,231...1,604,979
Ensembl chrNW_004955528:1,595,231...1,604,979
JBrowse link
G Nfatc1 nuclear factor of activated T cells 1 ISO (MGI:MGI:1197815|PMID:9515964) MGI PMID:9515964 MGI:MGI:1197815 NCBI chrNW_004955402:62,558,392...62,674,347
Ensembl chrNW_004955402:62,558,286...62,674,457
JBrowse link
G Nos3 nitric oxide synthase 3 ISO (MGI:MGI:3609262|PMID:10821808), (MGI:MGI:6158885|PMID:23583836)
BHF-UCL PMID:10821808, PMID:23583836, PMID:27107132 MGI:MGI:3609262, MGI:MGI:6158784, MGI:MGI:6158885 NCBI chrNW_004955491:5,438,228...5,457,308
Ensembl chrNW_004955491:5,438,010...5,460,814
JBrowse link
G Notch1 notch receptor 1 ISO (MGI:MGI:6158728|PMID:26491108)
(MGI:MGI:6158784|PMID:27107132), (MGI:MGI:6158885|PMID:23583836)
(PMID:16025100), (PMID:17662764), (PMID:18593716)
BHF-UCL PMID:16025100, PMID:17662764, PMID:18593716, PMID:23583836, PMID:26491108, PMID:27107132 MGI:MGI:6158728, MGI:MGI:6158784, MGI:MGI:6158885 NCBI chrNW_004955513:4,225,939...4,264,875
Ensembl chrNW_004955513:4,225,956...4,263,259
JBrowse link
G Rb1 RB transcriptional corepressor 1 ISO (MGI:MGI:6112863|PMID:29304157) BHF-UCL PMID:29304157 MGI:MGI:6112863 NCBI chrNW_004955431:1,960,765...2,124,576
Ensembl chrNW_004955431:1,960,661...2,124,576
JBrowse link
G Robo1 roundabout guidance receptor 1 ISO (MGI:MGI:5913048|PMID:25691540) BHF-UCL PMID:25691540 MGI:MGI:5913048 NCBI chrNW_004955407:12,593,911...13,485,723
Ensembl chrNW_004955407:13,107,235...13,487,053
JBrowse link
G Robo2 roundabout guidance receptor 2 ISO (MGI:MGI:5913048|PMID:25691540) BHF-UCL PMID:25691540 MGI:MGI:5913048 NCBI chrNW_004955407:14,301,689...15,549,561
Ensembl chrNW_004955407:14,305,498...14,842,790
JBrowse link
G Rock1 Rho associated coiled-coil containing protein kinase 1 ISO (PMID:26634652) BHF-UCL PMID:26634652 NCBI chrNW_004955402:9,752,101...9,864,317
Ensembl chrNW_004955402:9,750,730...9,864,317
JBrowse link
G Rock2 Rho associated coiled-coil containing protein kinase 2 ISO (PMID:26634652) BHF-UCL PMID:26634652 NCBI chrNW_004955487:5,856,190...5,972,408
Ensembl chrNW_004955487:5,859,204...5,972,401
JBrowse link
G Slit2 slit guidance ligand 2 ISO (MGI:MGI:5913048|PMID:25691540) BHF-UCL PMID:25691540 MGI:MGI:5913048 NCBI chrNW_004955480:3,982,977...4,314,160
Ensembl chrNW_004955480:3,984,586...4,313,908
JBrowse link
G Slit3 slit guidance ligand 3 ISO (MGI:MGI:5913048|PMID:25691540) BHF-UCL PMID:25691540 MGI:MGI:5913048 NCBI chrNW_004955408:21,719,487...22,322,958
Ensembl chrNW_004955408:21,722,632...22,322,917
JBrowse link
G Smad6 SMAD family member 6 ISO (PMID:22275001) BHF-UCL PMID:22275001 NCBI chrNW_004955450:9,005,332...9,070,790 JBrowse link
G Sox9 SRY-box transcription factor 9 ISO (PMID:22110751) BHF-UCL PMID:22110751 NCBI chrNW_004955478:941,684...945,563
Ensembl chrNW_004955478:940,177...945,563
JBrowse link
G Tbx20 T-box transcription factor 20 ISO (PMID:18275040), (PMID:18834961) BHF-UCL PMID:18275040, PMID:18834961 NCBI chrNW_004955460:7,794,313...7,856,906
Ensembl chrNW_004955460:7,794,313...7,856,906
JBrowse link
G Tgfb1 transforming growth factor beta 1 ISO (PMID:26634652)
BHF-UCL PMID:26634652 MGI:MGI:5921830 NCBI chrNW_004955555:274,405...288,441
Ensembl chrNW_004955555:270,652...288,441
JBrowse link
G Twist1 twist family bHLH transcription factor 1 ISO (MGI:MGI:4838344|PMID:20804746)
BHF-UCL PMID:20804746 MGI:MGI:4838344 NCBI chrNW_004955410:22,003,981...22,005,483 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 11892
    developmental process 5616
      anatomical structure morphogenesis 2500
        heart valve morphogenesis 48
          aortic valve morphogenesis 21
            aortic valve formation 0
Path 2
Term Annotations click to browse term
  biological_process 11892
    developmental process 5616
      anatomical structure development 5254
        multicellular organism development 4812
          system development 4532
            animal organ development 3490
              heart development 620
                heart valve development 58
                  semi-lunar valve development 34
                    aortic valve development 26
                      aortic valve morphogenesis 21
                        aortic valve formation 0
paths to the root


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.