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ONTOLOGY REPORT - ANNOTATIONS


Term:aortic valve morphogenesis
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Accession:GO:0003180 term browser browse the term
Definition:The process in which the structure of the aortic valve is generated and organized.


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aortic valve morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP4 bone morphogenetic protein 4 ISS BHF-UCL GO_REF:0000024 NCBI chr14:53,949,736...53,956,891
Ensembl chr14:53,949,736...53,958,761
JBrowse link
G DLL4 delta like canonical Notch ligand 4 IC (PMID:26491108) BHF-UCL PMID:26491108 NCBI chr15:40,929,340...40,939,073
Ensembl chr15:40,929,340...40,939,073
JBrowse link
G EFNA1 ephrin A1 ISS BHF-UCL GO_REF:0000024 NCBI chr 1:155,127,876...155,134,899
Ensembl chr 1:155,127,876...155,134,899
JBrowse link
G ELN elastin IC (PMID:8132745) BHF-UCL PMID:8132745 NCBI chr 7:74,027,772...74,069,907
Ensembl chr 7:74,027,789...74,069,907
JBrowse link
G EMILIN1 elastin microfibril interfacer 1 ISS BHF-UCL GO_REF:0000024 NCBI chr 2:27,078,615...27,086,403
Ensembl chr 2:27,078,615...27,086,403
JBrowse link
G GATA3 GATA binding protein 3 ISS UniProtKB GO_REF:0000024 NCBI chr10:8,045,420...8,075,198
Ensembl chr10:8,045,378...8,075,198
JBrowse link
G GATA4 GATA binding protein 4 IMP (PMID:29325903) BHF-UCL PMID:29325903 NCBI chr 8:11,676,931...11,760,002
Ensembl chr 8:11,676,959...11,760,002
JBrowse link
G GATA5 GATA binding protein 5 ISS
IMP
(PMID:22641149), (PMID:24638895) BHF-UCL PMID:22641149, PMID:24638895 GO_REF:0000024 NCBI chr20:62,463,497...62,475,995
Ensembl chr20:62,463,497...62,475,995
JBrowse link
G HEY2 hes related family bHLH transcription factor with YRPW motif 2 TAS (PMID:20951801) BHF-UCL PMID:20951801 NCBI chr 6:125,747,639...125,762,243
Ensembl chr 6:125,747,664...125,761,269
JBrowse link
G HEYL hes related family bHLH transcription factor with YRPW motif like TAS (PMID:20951801) BHF-UCL PMID:20951801 NCBI chr 1:39,623,435...39,639,643
Ensembl chr 1:39,623,435...39,639,643
JBrowse link
G JAG1 jagged canonical Notch ligand 1 NAS (PMID:20951801) BHF-UCL PMID:20951801 NCBI chr20:10,637,684...10,673,999
Ensembl chr20:10,637,684...10,673,999
JBrowse link
G NFATC1 nuclear factor of activated T cells 1 ISS BHF-UCL GO_REF:0000024 NCBI chr18:79,395,930...79,529,323
Ensembl chr18:79,395,856...79,529,325
JBrowse link
G NOS3 nitric oxide synthase 3 ISS BHF-UCL GO_REF:0000024 NCBI chr 7:150,991,017...151,014,588
Ensembl chr 7:150,991,017...151,014,588
JBrowse link
G NOTCH1 notch receptor 1 TAS
ISS
IMP
(PMID:20951801)
(PMID:16025100), (PMID:17662764), (PMID:18593716)
BHF-UCL PMID:16025100, PMID:17662764, PMID:18593716, PMID:20951801 GO_REF:0000024 NCBI chr 9:136,494,433...136,546,048
Ensembl chr 9:136,494,433...136,546,048
JBrowse link
G RB1 RB transcriptional corepressor 1 ISS BHF-UCL GO_REF:0000024 NCBI chr13:48,303,751...48,481,890
Ensembl chr13:48,303,744...48,599,436
Ensembl chr13:48,303,744...48,599,436
JBrowse link
G ROBO1 roundabout guidance receptor 1 ISS BHF-UCL GO_REF:0000024 NCBI chr 3:78,597,239...79,767,998
Ensembl chr 3:78,597,239...79,767,998
JBrowse link
G ROBO2 roundabout guidance receptor 2 ISS BHF-UCL GO_REF:0000024 NCBI chr 3:75,906,675...77,649,964
Ensembl chr 3:75,906,695...77,649,964
JBrowse link
G ROCK1 Rho associated coiled-coil containing protein kinase 1 ISS BHF-UCL GO_REF:0000024 NCBI chr18:20,946,906...21,111,813
Ensembl chr18:20,946,906...21,111,813
JBrowse link
G ROCK2 Rho associated coiled-coil containing protein kinase 2 ISS BHF-UCL GO_REF:0000024 NCBI chr 2:11,179,759...11,345,437
Ensembl chr 2:11,179,759...11,348,330
JBrowse link
G SLIT2 slit guidance ligand 2 ISS BHF-UCL GO_REF:0000024 NCBI chr 4:20,251,905...20,620,561
Ensembl chr 4:20,251,905...20,620,561
JBrowse link
G SLIT3 slit guidance ligand 3 ISS BHF-UCL GO_REF:0000024 NCBI chr 5:168,661,740...169,301,139
Ensembl chr 5:168,661,733...169,301,129
Ensembl chr 5:168,661,733...169,301,129
JBrowse link
G SMAD6 SMAD family member 6 IMP (PMID:22275001) BHF-UCL PMID:22275001 NCBI chr15:66,702,110...66,782,849
Ensembl chr15:66,702,236...66,782,849
JBrowse link
G SNAI1 snail family transcriptional repressor 1 TAS (PMID:20951801) BHF-UCL PMID:20951801 NCBI chr20:49,982,980...49,988,886
Ensembl chr20:49,982,980...49,988,886
JBrowse link
G SNAI2 snail family transcriptional repressor 2 TAS (PMID:20951801) BHF-UCL PMID:20951801 NCBI chr 8:48,917,598...48,921,429
Ensembl chr 8:48,917,598...48,921,740
JBrowse link
G SOX9 SRY-box transcription factor 9 IDA (PMID:22110751) BHF-UCL PMID:22110751 NCBI chr17:72,121,020...72,126,416
Ensembl chr17:72,121,020...72,126,416
JBrowse link
G TBX20 T-box transcription factor 20 IMP (PMID:18275040), (PMID:18834961) BHF-UCL PMID:18275040, PMID:18834961 NCBI chr 7:35,199,936...35,254,100
Ensembl chr 7:35,202,430...35,254,100
JBrowse link
G TGFB1 transforming growth factor beta 1 IMP
IEA
(PMID:26634652) BHF-UCL
Ensembl
PMID:26634652 GO_REF:0000107 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922
JBrowse link
G TWIST1 twist family bHLH transcription factor 1 IMP (PMID:20804746) BHF-UCL PMID:20804746 NCBI chr 7:19,113,047...19,117,636
Ensembl chr 7:19,020,991...19,117,636
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18670
    developmental process 7464
      anatomical structure morphogenesis 3095
        heart valve morphogenesis 53
          aortic valve morphogenesis 28
            aortic valve formation 0
Path 2
Term Annotations click to browse term
  biological_process 18670
    developmental process 7464
      anatomical structure development 6871
        multicellular organism development 6344
          system development 5748
            animal organ development 4412
              heart development 707
                heart valve development 63
                  semi-lunar valve development 38
                    aortic valve development 33
                      aortic valve morphogenesis 28
                        aortic valve formation 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.