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Term:aortic valve morphogenesis
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Accession:GO:0003180 term browser browse the term
Definition:The process in which the structure of the aortic valve is generated and organized.

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aortic valve morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 ISO (MGI:MGI:3039210|PMID:15070745), (MGI:MGI:3814273|PMID:18924235) BHF-UCL PMID:15070745, PMID:18924235 MGI:MGI:3039210, MGI:MGI:3814273 NCBI chrNW_004936697:1,054,237...1,061,468 JBrowse link
G Efna1 ephrin A1 ISO (MGI:MGI:4847981|PMID:20960543) BHF-UCL PMID:20960543 MGI:MGI:4847981 NCBI chrNW_004936580:4,654,503...4,660,950 JBrowse link
G Emilin1 elastin microfibril interfacer 1 ISO (MGI:MGI:5605894|PMID:25056700) BHF-UCL PMID:25056700 MGI:MGI:5605894 NCBI chrNW_004936493:5,455,369...5,463,205 JBrowse link
G Gata3 GATA binding protein 3 ISO (MGI:MGI:3832106|PMID:18955134) UniProtKB PMID:18955134 MGI:MGI:3832106 NCBI chrNW_004936484:6,780,692...6,800,883 JBrowse link
G Gata4 GATA binding protein 4 ISO (PMID:29325903) BHF-UCL PMID:29325903 NCBI chrNW_004936675:3,408,549...3,420,828 JBrowse link
G Gata5 GATA binding protein 5 ISO (PMID:22641149), (PMID:24638895)
BHF-UCL PMID:21633169, PMID:22641149, PMID:24638895 MGI:MGI:5286818 NCBI chrNW_004936514:10,061,675...10,070,541 JBrowse link
G Nfatc1 nuclear factor of activated T cells 1 ISO (MGI:MGI:1197815|PMID:9515964) MGI PMID:9515964 MGI:MGI:1197815 NCBI chrNW_004936616:484,062...584,950 JBrowse link
G Nos3 nitric oxide synthase 3 ISO (MGI:MGI:3609262|PMID:10821808), (MGI:MGI:6158885|PMID:23583836)
BHF-UCL PMID:10821808, PMID:23583836, PMID:27107132 MGI:MGI:3609262, MGI:MGI:6158784, MGI:MGI:6158885 NCBI chrNW_004936527:6,427,147...6,445,770 JBrowse link
G Notch1 notch receptor 1 ISO (MGI:MGI:6158728|PMID:26491108)
(MGI:MGI:6158784|PMID:27107132), (MGI:MGI:6158885|PMID:23583836)
(PMID:16025100), (PMID:17662764), (PMID:18593716)
BHF-UCL PMID:16025100, PMID:17662764, PMID:18593716, PMID:23583836, PMID:26491108, PMID:27107132 MGI:MGI:6158728, MGI:MGI:6158784, MGI:MGI:6158885 NCBI chrNW_004936669:1,292,016...1,334,061 JBrowse link
G Rb1 RB transcriptional corepressor 1 ISO (MGI:MGI:6112863|PMID:29304157) BHF-UCL PMID:29304157 MGI:MGI:6112863 NCBI chrNW_004936565:1,596,227...1,746,706 JBrowse link
G Robo1 roundabout guidance receptor 1 ISO (MGI:MGI:5913048|PMID:25691540) BHF-UCL PMID:25691540 MGI:MGI:5913048 NCBI chrNW_004936505:4,329,428...4,711,310 JBrowse link
G Robo2 roundabout guidance receptor 2 ISO (MGI:MGI:5913048|PMID:25691540) BHF-UCL PMID:25691540 MGI:MGI:5913048 NCBI chrNW_004936505:5,544,011...6,747,417 JBrowse link
G Rock1 Rho associated coiled-coil containing protein kinase 1 ISO (PMID:26634652) BHF-UCL PMID:26634652 NCBI chrNW_004936550:730,462...874,601 JBrowse link
G Rock2 Rho associated coiled-coil containing protein kinase 2 ISO (PMID:26634652) BHF-UCL PMID:26634652 NCBI chrNW_004936532:7,142,580...7,284,722 JBrowse link
G Slit2 slit guidance ligand 2 ISO (MGI:MGI:5913048|PMID:25691540) BHF-UCL PMID:25691540 MGI:MGI:5913048 NCBI chrNW_004936477:8,111,212...8,448,567 JBrowse link
G Slit3 slit guidance ligand 3 ISO (MGI:MGI:5913048|PMID:25691540) BHF-UCL PMID:25691540 MGI:MGI:5913048 NCBI chrNW_004936622:191,165...756,552 JBrowse link
G Smad6 SMAD family member 6 ISO (PMID:22275001) BHF-UCL PMID:22275001 NCBI chrNW_004936471:26,781,420...26,856,556 JBrowse link
G Sox9 SRY-box transcription factor 9 ISO (PMID:22110751) BHF-UCL PMID:22110751 NCBI chrNW_004936655:1,849,044...1,852,648 JBrowse link
G Tbx20 T-box transcription factor 20 ISO (PMID:18275040), (PMID:18834961) BHF-UCL PMID:18275040, PMID:18834961 NCBI chrNW_004936478:10,887,900...10,939,510 JBrowse link
G Tgfb1 transforming growth factor beta 1 ISO (PMID:26634652)
BHF-UCL PMID:26634652 MGI:MGI:5921830 NCBI chrNW_004936661:3,742,080...3,758,266 JBrowse link
G Twist1 twist family bHLH transcription factor 1 ISO (MGI:MGI:4838344|PMID:20804746)
BHF-UCL PMID:20804746 MGI:MGI:4838344 NCBI chrNW_004936546:5,331,220...5,332,669 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12001
    developmental process 5648
      anatomical structure morphogenesis 2519
        heart valve morphogenesis 47
          aortic valve morphogenesis 21
            aortic valve formation 0
Path 2
Term Annotations click to browse term
  biological_process 12001
    developmental process 5648
      anatomical structure development 5286
        multicellular organism development 4845
          system development 4567
            animal organ development 3514
              heart development 629
                heart valve development 57
                  semi-lunar valve development 34
                    aortic valve development 26
                      aortic valve morphogenesis 21
                        aortic valve formation 0
paths to the root


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.