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ONTOLOGY REPORT - ANNOTATIONS


Term:cardioblast proliferation
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Accession:GO:0003263 term browser browse the term
Definition:The multiplication or reproduction of cardioblasts, resulting in the expansion of the population in the heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.


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Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Notch1 notch receptor 1 JBrowse link 3 3,905,562 3,951,015 RGD:1624291
RGD:1600115
positive regulation of cardioblast proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pim1 Pim-1 proto-oncogene, serine/threonine kinase JBrowse link 20 8,165,423 8,169,557 RGD:1624291
RGD:1600115
positive regulation of secondary heart field cardioblast proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Eya1 EYA transcriptional coactivator and phosphatase 1 JBrowse link 5 4,275,728 4,495,525 RGD:1624291
G Gng5 G protein subunit gamma 5 JBrowse link 2 252,359,976 252,368,473 RGD:1624291
G Six1 SIX homeobox 1 JBrowse link 6 95,929,060 95,934,296 RGD:1624291
RGD:1600115
G Tbx1 T-box transcription factor 1 JBrowse link 11 86,552,022 86,561,647 RGD:1624291
G Tbx5 T-box transcription factor 5 JBrowse link 12 42,059,688 42,148,226 RGD:1624291
RGD:1600115
regulation of cardioblast proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Notch1 notch receptor 1 JBrowse link 3 3,905,562 3,951,015 RGD:2325311
regulation of secondary heart field cardioblast proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ctnnb1 catenin beta 1 JBrowse link 8 129,601,511 129,628,378 RGD:1624291
RGD:1600115
G Hand2 heart and neural crest derivatives expressed 2 JBrowse link 16 36,371,489 36,373,551 RGD:1624291
G Hes1 hes family bHLH transcription factor 1 JBrowse link 11 74,312,837 74,315,249 RGD:1624291
RGD:1600115
G Isl1 ISL LIM homeobox 1 JBrowse link 2 48,488,911 48,501,217 RGD:1624291
RGD:1600115
smoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mks1 MKS transition zone complex subunit 1 JBrowse link 10 75,149,814 75,160,481 RGD:1600115
RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18008
    cell population proliferation 2090
      cell proliferation involved in heart morphogenesis 23
        cardioblast proliferation 12
          negative regulation of cardioblast proliferation 0
          positive regulation of cardioblast proliferation 1
          regulation of cardioblast proliferation + 12
Path 2
Term Annotations click to browse term
  biological_process 18008
    developmental process 6505
      anatomical structure development 5993
        multicellular organism development 5478
          system development 5028
            animal organ development 3848
              animal organ morphogenesis 1113
                animal organ formation 74
                  heart formation 31
                    cardioblast proliferation 12
                      negative regulation of cardioblast proliferation 0
                      positive regulation of cardioblast proliferation 1
                      regulation of cardioblast proliferation + 12
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.